iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oar-090330

Ensembl Protein ID

ENSOARP00000000970.1

UniProt Accession

W5NS30; W5NS30_SHEEP

Genbank Protein ID

ENSOARP00000000970

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AMGL01103869

Gene Name

SOCS4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOARG00000000938.1	ENSOART00000001003.1	ENSOARP00000000970.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box	5.00e-17	61.7	378	425

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box

   S: 3    klwllrseprSLqhLCRlaIrrclgsqrlkaidkLPLPksLkdYLlyedyq 53
           +++l+r+ p+SLqh+CR +I++c++++++   d+LP+P+s+k YL++++y+
   Q: 378  STPLIRTFPFSLQHICRTVICNCTTYDGI---DALPIPSSMKLYLKEYHYK 425
           678899***********************...****************985 PP

Organism

Ovis aries

Protein Sequence
(Fasta)

MAENSESNSK NVDVRPKTSR SRSADRKDGY VWSGKKLSWS KKSESCSDAE TVSAIEKTEV 60
PLRSQERKHS CSSIELDLDH SCGHRFLGRS LKQKLQDAVG QCFPIKNCSS RHSSGLPSKR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCAGAAA ATAGTGAAAG TAATAGTAAA AATGTAGATG TAAGGCCCAA AACTAGCCGG 60
AGTCGAAGTG CTGACAGAAA GGATGGTTAT GTGTGGAGTG GAAAGAAGTT ATCTTGGTCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000980--SH2
IPR028416--SOCS4
IPR022252--SOCS4/SOCS5_dom
IPR001496--SOCS_box

PROSITE

PS50001--SH2
PS50225--SOCS

Pfam

PF00017--SH2
PF12610--SOCS
PF07525--SOCS_box

SMART

SM00252--SH2
SM00253--SOCS
SM00969--SOCS_box

Gene Ontology

GO:0005622--C:intracellular
GO:0035556--P:intracellular signal transduction
GO:0007175--P:negative regulation of epidermal growth factor-activated receptor activity
GO:0032436--P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0016567--P:protein ubiquitination

KEGG

oas:101117935

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001789	Ailuropoda melanoleuca	94.75	0.00e+00	799.00
IUUC-Apl-003839	Anas platyrhynchos	81.09	0.00e+00	652.00
IUUC-Aca-004840	Anolis carolinensis	77.68	0.00e+00	699.00
IUUC-Ame-010732	Astyanax mexicanus	79.65	1.00e-85	310.00
IUUC-Bta-012503	Bos taurus	99.32	0.00e+00	834.00
IUUC-Bol-016597	Brassica oleracea	29.11	1.90e-01	30.80
IUUC-Cja-019284	Callithrix jacchus	92.73	0.00e+00	778.00
IUUC-Cfa-020890	Canis familiaris	93.86	0.00e+00	793.00
IUUC-Cpo-022081	Cavia porcellus	79.15	0.00e+00	684.00
IUUC-Csa-023076	Chlorocebus sabaeus	92.27	0.00e+00	780.00
IUUC-Cho-024700	Choloepus hoffmanni	93.88	0.00e+00	830.00
IUUC-Dno-029961	Dasypus novemcinctus	94.33	0.00e+00	828.00
IUUC-Dor-030273	Dipodomys ordii	92.74	0.00e+00	789.00
IUUC-Ete-032972	Echinops telfairi	92.31	6.00e-170	589.00
IUUC-Eca-034289	Equus caballus	94.33	0.00e+00	793.00
IUUC-Eeu-035208	Erinaceus europaeus	91.26	0.00e+00	755.00
IUUC-Fal-036829	Ficedula albicollis	80.87	0.00e+00	647.00
IUUC-Gga-040725	Gallus gallus	79.27	0.00e+00	669.00
IUUC-Ggo-044886	Gorilla gorilla	93.20	0.00e+00	783.00
IUUC-Hsa-046322	Homo sapiens	92.97	0.00e+00	781.00
IUUC-Itr-048585	Ictidomys tridecemlineatus	94.25	0.00e+00	790.00
IUUC-Lch-049459	Latimeria chalumnae	57.99	2.00e-138	485.00
IUUC-Loc-052058	Lepisosteus oculatus	44.52	9.00e-92	330.00
IUUC-Laf-053484	Loxodonta africana	94.25	0.00e+00	786.00
IUUC-Mcc-054890	Macaca mulatta	92.05	0.00e+00	778.00
IUUC-Meu-056532	Macropus eugenii	84.05	0.00e+00	645.00
IUUC-Mtr-057670	Medicago truncatula	36.67	2.00e+00	26.60
IUUC-Mvi-060418	Microbotryum violaceum	32.10	1.50e-02	32.70
IUUC-Mmr-061714	Microcebus murinus	94.33	0.00e+00	791.00
IUUC-Mmu-063161	Mus musculus	87.02	0.00e+00	737.00
IUUC-Mac-064598	Musa acuminata	31.71	3.50e-01	28.10
IUUC-Mpu-066499	Mustela putorius furo	94.32	0.00e+00	816.00
IUUC-Mlu-066945	Myotis lucifugus	93.20	0.00e+00	780.00
IUUC-Nle-069976	Nomascus leucogenys	92.97	0.00e+00	780.00
IUUC-Opr-070255	Ochotona princeps	88.41	0.00e+00	763.00
IUUC-Ocu-074764	Oryctolagus cuniculus	94.78	0.00e+00	801.00
IUUC-Oga-088910	Otolemur garnettii	87.56	0.00e+00	764.00
IUUC-Ptr-090709	Pan troglodytes	93.20	0.00e+00	783.00
IUUC-Pan-092540	Papio anubis	92.27	0.00e+00	780.00
IUUC-Psi-093678	Pelodiscus sinensis	81.55	0.00e+00	721.00
IUUC-Pfo-097139	Poecilia formosa	80.81	4.00e-87	315.00
IUUC-Pab-097970	Pongo abelii	91.18	0.00e+00	637.00
IUUC-Pop-098820	Populus trichocarpa	41.18	1.30e-01	30.80
IUUC-Pca-100211	Procavia capensis	83.22	0.00e+00	674.00
IUUC-Rno-106014	Rattus norvegicus	84.74	0.00e+00	727.00
IUUC-Sha-106822	Sarcophilus harrisii	84.51	0.00e+00	721.00
IUUC-Ssc-115821	Sus scrofa	96.15	0.00e+00	809.00
IUUC-Tgu-117117	Taeniopygia guttata	81.09	0.00e+00	650.00
IUUC-Tsy-118979	Tarsius syrichta	96.17	8.00e-125	439.00
IUUC-Tca-121131	Theobroma cacao	30.77	2.00e-03	36.60
IUUC-Vpa-130626	Vicugna pacos	96.15	0.00e+00	817.00
IUUC-Vvi-131327	Vitis vinifera	43.24	1.00e-01	31.20
IUUC-Xtr-132138	Xenopus tropicalis	70.62	2.00e-177	615.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence