iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Eca-034394

UUCD1 version

UUC-EqC-00073

Ensembl Protein ID

ENSECAP00000010144.1

UniProt Accession

F6QQI1; F6QQI1_HORSE

Protein Name

Uncharacterized protein

Gene Name

CUL9

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000011751.1	ENSECAT00000012837.1	ENSECAP00000010144.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/Cullin	7.50e-133	444.6	1299	1819

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/Cullin

   S: 65   lLktynreWekfreqlkvlrkifayldrtyvkkskkvsevrkLaldlwrkeivedikkrllelllklieaeRkgeavdrrllsgvve 151
           +L    ++W+ freql++ +++f      y+ +           +++w+++i+ed +krll+l+ +l++ +R+++++++r+l+++++
   Q: 1299 VLGPKATFWPLFREQLCRRTCLF------YTIR-----------AQAWSQDIAED-RKRLLQLCPRLNRVLRHEQNFADRFLPDDEA 1367
           6666789****************......9999...........***********.******************************* PP
   S: 152  slveLslnklaiykesFEakfleatqefykaesaeflqe.nevdeYlkkvearlneeeeraaryleestetkLlevvekeliakhle 237
           +        +a++k+++Ea++++ +q++++++++ +++  + +d+Yl+++e++ n+ +++a+++++++++++Ll++ve+   +    
   Q: 1368 A--------QALGKTCWEALVSPLVQNITSPDAEGVSSLgWLLDQYLEHRESSRNPLSRAASFASRVRRLCHLLVHVEPPPGP---- 1442
           *........**************************************************************************.... PP
   S: 238  sllaelvallrdkktedlsrmykLlsrvln..gleellkeleshikeqgkaaltaeekekdpkkyVerllelknklqklvseaFnnd 322
              ++ +++   +k+++ ++ + + s vl+  +l+++++++ s+++eq++++l+a++++ d   +V+r++el+++lq++ se+F+++
   Q: 1443 ---SPEPSTRPFSKNSKGRDRSPVPSPVLPssSLRNITQCWLSVVQEQVSRFLAAAWRAPD---FVPRYCELYEHLQRAGSELFGPR 1523
           ...***************************99*****************************...*********************** PP
   S: 323  akFlkaldkafetfvnknsvlkaakspEllAryiDqlLrks.skglteeeleaqldkvllvfkyisekdv...FekyYkkhLakRLl 405
           a+F+ al+++f+ +++++s+l+aa+++E++Ar+iDq+++++ ++g+ + e++ +l+++l+ ++++s++++   Fe++Y++++a+RLl
   Q: 1524 AAFTLALRSGFSGALLQQSFLTAAHMSEQFARHIDQQIQGGlMGGAPGVEVLGRLQRHLEPIMVLSGLELattFEHFYQHYMADRLL 1610
           *************************************************************************************** PP
   S: 406  sgksasseaEesviekLkeecgaeftskL.erMfqdlkvSedlnrqFk..................................eeken 457
           s    s ++E++v+e++    g++f+++L ++M+++l++Se+l+rqF+                                  +eke 
   Q: 1611 S--LGSRWLEGAVLEQI----GLCFPNRLpQQMLRSLSTSEELQRQFHlfqlqwfdkllldkeddeeqgleedevrarekkeAEKEL 1691
           *..**************....***********************************************************9999999 PP
   S: 458  teesesvelsvlvLsagaWpta..set..ekvsLPaelektiekfeefY........lekhsgRkLqWqhtlgraelkaelkkgkye 532
             e++s+++svlvLs+++Wp++  + +  ++ +LP+el+++++ f++fY        l+++++R+L+W++ lgrael++    g ++
   Q: 1692 FIEDPSPAVSVLVLSPRCWPVSplCYMyhPRKCLPTELCDALDCFSNFYsqsqnhpvLDMGPHRRLKWTW-LGRAELHF----GDQT 1773
           9*********************9987788*****************************************.********....**** PP
   S: 533  lqVstfQmavLLafnnsekvsveelkkatelpeeeLrrtlqsLvssk 579
           l+Vst+Qm++LL fn+ e+vsve+l k++ l +e+L ++l +L+s +
   Q: 1774 LHVSTVQMWLLLNFNQMEEVSVETLLKSS-LTPELLLQALLPLTSEN 1819
           *************************9865.788889999****9976 PP

Organism

Equus caballus

Protein Sequence
(Fasta)

MVGERRTGDL MVPLGPRLQA YPEELIRQRP GHDGRPEYLI RWSVLKCGEV GRVGVEEGKA 60
EHILMWLSAP EVYANCPMLL GEPAVSKGPQ HEPAGGSGSF PRDPGGLDDV AMGEMEADVR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGTGGGGG AACGGCGCAC TGGGGACCTC ATGGTGCCCC TGGGGCCCCG GCTGCAGGCA 60
TATCCTGAAG AACTTATTCG ACAGCGGCCT GGGCACGATG GACGTCCTGA ATACCTGATC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR004939--APC_su10/DOC_dom
IPR011989--ARM-like
IPR016024--ARM-type_fold
IPR016150--Casein_kin_II_reg-sub_b-sht
IPR021097--CPH_domain
IPR031222--CUL9
IPR016157--Cullin_CS
IPR016158--Cullin_homology
IPR001373--Cullin_N
IPR019559--Cullin_neddylation_domain
IPR008979--Galactose-bd-like
IPR002867--IBR_dom
IPR014722--Rib_L2_dom2
IPR011991--WHTH_DNA-bd_dom
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS01256--CULLIN_1
PS50069--CULLIN_2
PS51284--DOC
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF03256--ANAPC10
PF11515--Cul7
PF00888--Cullin
PF10557--Cullin_Nedd8
PF01485--IBR

SMART

SM01337--APC10
SM00884--Cullin_Nedd8
SM00647--IBR

Gene Ontology

GO:0031461--C:cullin-RING ubiquitin ligase complex
GO:0005829--C:cytosol
GO:0008270--F:zinc ion binding
GO:0000226--P:microtubule cytoskeleton organization
GO:0016567--P:protein ubiquitination
GO:0007088--P:regulation of mitotic nuclear division
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001405	Ailuropoda melanoleuca	92.38	0.00e+00	4408.00
IUUC-Apl-003458	Anas platyrhynchos	63.17	0.00e+00	757.00
IUUC-Aca-004815	Anolis carolinensis	56.29	0.00e+00	2537.00
IUUC-Ame-010611	Astyanax mexicanus	50.23	0.00e+00	2244.00
IUUC-Bta-012877	Bos taurus	90.43	0.00e+00	4148.00
IUUC-Cja-019255	Callithrix jacchus	90.90	0.00e+00	4224.00
IUUC-Cfa-020119	Canis familiaris	92.83	0.00e+00	4370.00
IUUC-Cpo-022473	Cavia porcellus	83.45	0.00e+00	3776.00
IUUC-Csa-024157	Chlorocebus sabaeus	91.02	0.00e+00	4201.00
IUUC-Cho-024879	Choloepus hoffmanni	84.55	0.00e+00	917.00
IUUC-Cin-025402	Ciona intestinalis	31.32	7.00e-107	382.00
IUUC-Dno-028904	Dasypus novemcinctus	88.89	0.00e+00	4151.00
IUUC-Dor-030112	Dipodomys ordii	86.55	0.00e+00	1342.00
IUUC-Ete-032516	Echinops telfairi	80.46	0.00e+00	1325.00
IUUC-Eeu-035166	Erinaceus europaeus	88.91	0.00e+00	2173.00
IUUC-Fca-035740	Felis catus	92.79	0.00e+00	4335.00
IUUC-Fal-036672	Ficedula albicollis	51.41	0.00e+00	1538.00
IUUC-Gga-040154	Gallus gallus	59.55	0.00e+00	876.00
IUUC-Ggo-045570	Gorilla gorilla	90.94	0.00e+00	4167.00
IUUC-Hsa-046690	Homo sapiens	90.98	0.00e+00	4151.00
IUUC-Itr-048680	Ictidomys tridecemlineatus	90.47	0.00e+00	4261.00
IUUC-Loc-052706	Lepisosteus oculatus	54.56	0.00e+00	1796.00
IUUC-Mcc-055727	Macaca mulatta	91.06	0.00e+00	4249.00
IUUC-Meu-056074	Macropus eugenii	75.43	0.00e+00	1493.00
IUUC-Mga-059683	Meleagris gallopavo	54.39	2.00e-103	369.00
IUUC-Mmr-060869	Microcebus murinus	90.94	0.00e+00	4278.00
IUUC-Mdo-062902	Monodelphis domestica	73.79	0.00e+00	3289.00
IUUC-Mmu-063991	Mus musculus	85.18	0.00e+00	3936.00
IUUC-Mpu-065974	Mustela putorius furo	91.96	0.00e+00	4304.00
IUUC-Nle-069292	Nomascus leucogenys	91.89	0.00e+00	2701.00
IUUC-Opr-071020	Ochotona princeps	85.68	0.00e+00	2133.00
IUUC-Ont-071953	Oreochromis niloticus	50.71	0.00e+00	2179.00
IUUC-Oan-073534	Ornithorhynchus anatinus	58.34	0.00e+00	2044.00
IUUC-Ocu-074244	Oryctolagus cuniculus	88.44	0.00e+00	4120.00
IUUC-Ola-087072	Oryzias latipes	53.87	0.00e+00	1708.00
IUUC-Oga-088310	Otolemur garnettii	88.13	0.00e+00	4186.00
IUUC-Oar-090174	Ovis aries	89.47	0.00e+00	4080.00
IUUC-Ptr-091410	Pan troglodytes	91.06	0.00e+00	4138.00
IUUC-Pan-091856	Papio anubis	91.45	0.00e+00	2674.00
IUUC-Pma-094192	Petromyzon marinus	45.12	0.00e+00	1405.00
IUUC-Pfo-096773	Poecilia formosa	54.91	0.00e+00	949.00
IUUC-Pab-098635	Pongo abelii	91.50	0.00e+00	2904.00
IUUC-Pca-100539	Procavia capensis	90.18	0.00e+00	1353.00
IUUC-Pva-102813	Pteropus vampyrus	86.88	0.00e+00	1691.00
IUUC-Rno-106105	Rattus norvegicus	85.26	0.00e+00	3949.00
IUUC-Sha-106896	Sarcophilus harrisii	76.94	0.00e+00	1157.00
IUUC-Ssl-108406	Sclerotinia sclerotiorum	26.83	3.00e-07	50.10
IUUC-Sar-113132	Sorex araneus	80.44	0.00e+00	1264.00
IUUC-Ssc-116000	Sus scrofa	91.16	0.00e+00	4224.00
IUUC-Tgu-116915	Taeniopygia guttata	63.23	2.00e-143	502.00
IUUC-Tru-118013	Takifugu rubripes	54.65	0.00e+00	1546.00
IUUC-Tsy-119037	Tarsius syrichta	80.77	0.00e+00	1105.00
IUUC-Tni-120062	Tetraodon nigroviridis	53.78	0.00e+00	1689.00
IUUC-Ttr-128780	Tursiops truncatus	88.12	0.00e+00	2715.00
IUUC-Vpa-130086	Vicugna pacos	86.11	0.00e+00	658.00
IUUC-Xtr-132882	Xenopus tropicalis	50.12	0.00e+00	1845.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence