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Basic Information Integrated Annotations
Tag Content
UUCD2 ID IUUC-Hsa-045856
UUCD1 version UUC-HoS-00792
Ensembl Protein ID ENSP00000436262.1
UniProt Accession Q8NAB2; Q6N066; Q86X38; Q96NK5; KBTB3_HUMAN
Genbank Protein ID BAC04012.1; CAE45804.1; EAW67073.1; AAI17467.1
Protein Name Kelch repeat and BTB domain-containing protein 3; BTB and kelch domain-containing protein 3
Genbank Nucleotide ID AK092993; BX640672; AP001001; BC117466
Gene Name KBTBD3; BKLHD3
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSG00000182359.14 ENST00000526793.5 ENSP00000436262.1
ENSG00000182359.14 ENST00000531482.2 ENSP00000475836.1
Annotation
Cancer Mutation
TCGAICGCCOSMICCGAP
IntOGen
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressTCGAICGC
COSMICTHPAHPM
DNA & RNA Element
UTRdbAREsitemiRTarBasemicroRNA
TRANSFACRepTarSomamiRmiRcode
RAID2
Protein-protein Interaction
IIDMentha
Disease-associated Variation
GWASdb
Post-translational Modifications (PTMs)
CPLMdbPAFPhosphositePlusdbPTM
BioGRIDmUbiSiDa
DNA Methylation
TCGAICGCCOSMIC
Protein Expression/Proteomics
THPAHPMGPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/BCR/BTB_Other: BTB 8.30e-17 63.0 53 117
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/BCR/BTB_Other: BTB
   S: 2    DvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgklde 67
           D  ++ ++e +++h++vLaa+S++F+a+f+ +++e++  + v+i  ++ ++++a+l++ Ytgk ++
   Q: 53   DFKIIMKDEIIPCHRCVLAACSDFFRAMFEVNMKERD-DGSVTITNLSSKAVKAFLDYAYTGKTKI 117
           7788999*****************************9.9***********************9876 PP
   
Organism Homo sapiens
Protein Sequence
(Fasta)
MELAMDNSYA FNQRSTCNGI PSEKKNNFLV SEDHGQKILS VLQNFREQNV FYDFKIIMKD 60
EIIPCHRCVL AACSDFFRAM FEVNMKERDD GSVTITNLSS KAVKAFLDYA YTGKTKITDD 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Hsa-045856|E3,BTB_Other|Homo sapiens
Please wait for a moment...
Nucleotide Sequence
(Fasta)
AGCGCACGCC CTCCATGGAT GGCACCAAGC AGAACCGTTT GGCAGGGAAA ACCATACACT 60
GAAAGCGGAC CTCGCCGCTA TCTCGGGCCT GATGGCGCGG ACGCAAACGT GGCCCCACCC 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Hsa-045856|E3,BTB_Other|Homo sapiens
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-0621--Polymorphism
KW-1185--Reference proteome
KW-0677--Repeat
Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR011333--SKP1/BTB/POZ
PROSITE

PS50097--BTB
Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1
SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch
Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0016567--P:protein ubiquitination
KEGG hsa:143879
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001820 Ailuropoda melanoleuca 93.75 0.00e+00 1171.00
IUUC-Apl-004123 Anas platyrhynchos 80.49 0.00e+00 934.00
IUUC-Aca-005246 Anolis carolinensis 78.89 0.00e+00 972.00
IUUC-Ame-011104 Astyanax mexicanus 60.30 0.00e+00 791.00
IUUC-Bta-012410 Bos taurus 94.91 0.00e+00 1183.00
IUUC-Cja-019776 Callithrix jacchus 97.71 0.00e+00 1227.00
IUUC-Cfa-020821 Canis familiaris 91.87 0.00e+00 1138.00
IUUC-Cpo-022132 Cavia porcellus 94.09 0.00e+00 1174.00
IUUC-Csa-023977 Chlorocebus sabaeus 99.51 0.00e+00 1240.00
IUUC-Cho-024321 Choloepus hoffmanni 92.48 0.00e+00 1159.00
IUUC-Dre-028355 Danio rerio 56.61 0.00e+00 715.00
IUUC-Dno-029781 Dasypus novemcinctus 93.28 0.00e+00 1009.00
IUUC-Dor-030247 Dipodomys ordii 93.94 0.00e+00 1204.00
IUUC-Eca-033508 Equus caballus 94.71 0.00e+00 1172.00
IUUC-Fca-035763 Felis catus 93.88 0.00e+00 1140.00
IUUC-Fal-036819 Ficedula albicollis 82.59 0.00e+00 1025.00
IUUC-Gmo-039621 Gadus morhua 56.40 0.00e+00 703.00
IUUC-Gac-041878 Gasterosteus aculeatus 59.33 0.00e+00 757.00
IUUC-Ggo-045140 Gorilla gorilla 99.84 0.00e+00 1244.00
IUUC-Itr-047879 Ictidomys tridecemlineatus 95.87 0.00e+00 1184.00
IUUC-Lch-050633 Latimeria chalumnae 77.81 0.00e+00 997.00
IUUC-Loc-052764 Lepisosteus oculatus 72.61 0.00e+00 898.00
IUUC-Laf-053837 Loxodonta africana 94.75 0.00e+00 1182.00
IUUC-Mcc-054786 Macaca mulatta 99.51 0.00e+00 1240.00
IUUC-Meu-056272 Macropus eugenii 86.58 0.00e+00 1098.00
IUUC-Mga-059623 Meleagris gallopavo 82.89 0.00e+00 1022.00
IUUC-Mdo-062546 Monodelphis domestica 88.58 0.00e+00 1101.00
IUUC-Mmu-063765 Mus musculus 91.40 0.00e+00 1137.00
IUUC-Mpu-065937 Mustela putorius furo 93.06 0.00e+00 1162.00
IUUC-Mlu-067218 Myotis lucifugus 92.43 0.00e+00 1190.00
IUUC-Nle-069590 Nomascus leucogenys 99.67 0.00e+00 1242.00
IUUC-Opr-070861 Ochotona princeps 94.61 0.00e+00 1186.00
IUUC-Ont-071884 Oreochromis niloticus 59.63 0.00e+00 762.00
IUUC-Oan-073097 Ornithorhynchus anatinus 71.31 0.00e+00 915.00
IUUC-Ocu-074426 Oryctolagus cuniculus 96.06 0.00e+00 1195.00
IUUC-Ola-086530 Oryzias latipes 58.80 0.00e+00 734.00
IUUC-Oga-088376 Otolemur garnettii 94.55 0.00e+00 1147.00
IUUC-Oar-090447 Ovis aries 94.75 0.00e+00 1180.00
IUUC-Ptr-091236 Pan troglodytes 100.00 0.00e+00 1244.00
IUUC-Pan-092642 Papio anubis 99.35 0.00e+00 1238.00
IUUC-Psi-093488 Pelodiscus sinensis 82.64 0.00e+00 1061.00
IUUC-Pfo-097337 Poecilia formosa 57.21 0.00e+00 753.00
IUUC-Pab-097762 Pongo abelii 97.40 0.00e+00 1199.00
IUUC-Pva-102185 Pteropus vampyrus 94.61 0.00e+00 1181.00
IUUC-Rno-104997 Rattus norvegicus 90.91 0.00e+00 1128.00
IUUC-Sha-106916 Sarcophilus harrisii 88.85 0.00e+00 1092.00
IUUC-Smo-109044 Selaginella moellendorffii 29.41 1.00e-15 75.90
IUUC-Ssc-115954 Sus scrofa 94.21 0.00e+00 1164.00
IUUC-Tgu-116522 Taeniopygia guttata 81.38 0.00e+00 1021.00
IUUC-Tru-118659 Takifugu rubripes 54.77 0.00e+00 669.00
IUUC-Tsy-119038 Tarsius syrichta 95.16 0.00e+00 1135.00
IUUC-Tni-120710 Tetraodon nigroviridis 56.53 0.00e+00 687.00
IUUC-Ttr-128430 Tursiops truncatus 93.09 0.00e+00 1104.00
IUUC-Vpa-130473 Vicugna pacos 94.56 0.00e+00 1029.00
IUUC-Xtr-132150 Xenopus tropicalis 76.79 0.00e+00 972.00
Created Date 25-Jun-2017

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