iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ame-011640

Ensembl Protein ID

ENSAMXP00000018217.1

UniProt Accession

W5LEF5; W5LEF5_ASTMX

Genbank Protein ID

ENSAMXP00000018217

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

APWO01001276

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMXG00000017688.1	ENSAMXT00000018217.1	ENSAMXP00000018217.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	1.30e-08	35.5	341	379
UBD/Alpha-Helix/CUE	3.00e-12	46.5	456	497

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           CaiC++++    + lpCgH+fh +Cl  w        +  +CP+Cr
   Q: 341  CAICWDSMTS-ARKLPCGHLFHNSCLRSW------LEQDTSCPTCR 379
           ********88.99****************......9*********8 PP

UBD/Alpha-Helix/CUE

   S: 1    dletaleqLkeiFPnldysviqvvLeantgsleaavnnLLegs 43
           +l+t+++q++e+FP+++y ++ ++L ++t s+e +++n+Leg 
   Q: 456  QLNTMAHQIQEMFPQVPYHLVLQDL-QLTRSVEVTTDNILEGR 497
           689**********************.***************95 PP

Organism

Astyanax mexicanus

Protein Sequence
(Fasta)

MPLLFLERFP WPSLQTYTAL STVLLAGSIL SAYTAVTQIP EPAAPVAEDA RTEPIEDSKA 60
DQGEAIEHVA SNVLLYLIAD NLFVWVMVNT ACCVLMLIAK VIQCIVFGPL RVSEKQHLKD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCCCCTGT TGTTTCTGGA GAGGTTCCCC TGGCCCAGCC TGCAGACCTA CACTGCGCTT 60
AGCACAGTCC TGCTCGCTGG TTCGATCCTC AGTGCCTACA CCGCTGTAAC CCAGATCCCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR003892--CUE
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51140--CUE
PS50089--ZF_RING_2

Pfam

PF02845--CUE
PF13639--zf-RING_2

SMART

SM00546--CUE
SM00184--RING

Gene Ontology

GO:0016021--C:integral component of membrane
GO:0008270--F:zinc ion binding

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001300	Ailuropoda melanoleuca	73.85	0.00e+00	807.00
IUUC-Apl-003404	Anas platyrhynchos	76.28	0.00e+00	811.00
IUUC-Aca-004559	Anolis carolinensis	76.68	0.00e+00	762.00
IUUC-Bta-012980	Bos taurus	68.65	0.00e+00	829.00
IUUC-Cel-018598	Caenorhabditis elegans	24.60	1.00e-36	147.00
IUUC-Cja-019577	Callithrix jacchus	71.76	0.00e+00	886.00
IUUC-Cfa-020793	Canis familiaris	74.54	0.00e+00	797.00
IUUC-Cpo-022387	Cavia porcellus	69.86	0.00e+00	867.00
IUUC-Csa-023168	Chlorocebus sabaeus	71.76	0.00e+00	886.00
IUUC-Cho-024433	Choloepus hoffmanni	74.00	0.00e+00	645.00
IUUC-Cin-025215	Ciona intestinalis	45.21	3.00e-148	518.00
IUUC-Csv-026133	Ciona savignyi	48.71	6.00e-135	474.00
IUUC-Dre-027594	Danio rerio	80.76	0.00e+00	882.00
IUUC-Dno-029407	Dasypus novemcinctus	73.78	0.00e+00	780.00
IUUC-Dor-030961	Dipodomys ordii	73.77	0.00e+00	800.00
IUUC-Ete-032962	Echinops telfairi	68.89	0.00e+00	669.00
IUUC-Eca-033683	Equus caballus	69.16	0.00e+00	823.00
IUUC-Eeu-034515	Erinaceus europaeus	78.52	7.00e-63	234.00
IUUC-Fca-035398	Felis catus	76.37	0.00e+00	779.00
IUUC-Fal-036758	Ficedula albicollis	69.57	0.00e+00	749.00
IUUC-Gmo-039014	Gadus morhua	73.28	0.00e+00	827.00
IUUC-Gga-040575	Gallus gallus	71.66	0.00e+00	847.00
IUUC-Gac-041414	Gasterosteus aculeatus	74.66	0.00e+00	799.00
IUUC-Hsa-046272	Homo sapiens	71.91	0.00e+00	888.00
IUUC-Itr-047956	Ictidomys tridecemlineatus	73.78	0.00e+00	799.00
IUUC-Lch-050491	Latimeria chalumnae	74.46	0.00e+00	837.00
IUUC-Loc-052758	Lepisosteus oculatus	74.92	0.00e+00	894.00
IUUC-Laf-053452	Loxodonta africana	72.28	0.00e+00	806.00
IUUC-Mcc-055820	Macaca mulatta	75.27	0.00e+00	798.00
IUUC-Meu-056726	Macropus eugenii	69.79	0.00e+00	709.00
IUUC-Mga-059937	Meleagris gallopavo	75.14	0.00e+00	806.00
IUUC-Mmr-060730	Microcebus murinus	72.09	0.00e+00	858.00
IUUC-Mdo-062771	Monodelphis domestica	70.42	0.00e+00	865.00
IUUC-Mmu-064219	Mus musculus	73.27	0.00e+00	880.00
IUUC-Mac-065495	Musa acuminata	28.12	5.00e-30	125.00
IUUC-Mpu-066796	Mustela putorius furo	74.01	0.00e+00	789.00
IUUC-Mlu-068189	Myotis lucifugus	73.41	0.00e+00	788.00
IUUC-Nle-069239	Nomascus leucogenys	71.32	0.00e+00	850.00
IUUC-Opr-070702	Ochotona princeps	63.67	2.00e-94	339.00
IUUC-Ont-072033	Oreochromis niloticus	71.38	0.00e+00	862.00
IUUC-Oan-073717	Ornithorhynchus anatinus	72.82	0.00e+00	746.00
IUUC-Ocu-074145	Oryctolagus cuniculus	72.30	0.00e+00	875.00
IUUC-Ogl-077929	Oryza glaberrima	51.16	2.00e-11	62.00
IUUC-Ola-087152	Oryzias latipes	68.07	0.00e+00	816.00
IUUC-Oga-088486	Otolemur garnettii	74.00	0.00e+00	802.00
IUUC-Oar-089310	Ovis aries	74.72	0.00e+00	808.00
IUUC-Ptr-090649	Pan troglodytes	75.18	0.00e+00	820.00
IUUC-Pan-091692	Papio anubis	67.94	0.00e+00	820.00
IUUC-Psi-093064	Pelodiscus sinensis	83.92	0.00e+00	699.00
IUUC-Pma-094763	Petromyzon marinus	77.05	2.00e-97	348.00
IUUC-Ppa-095969	Physcomitrella patens	30.50	2.00e-38	154.00
IUUC-Pfo-096810	Poecilia formosa	71.71	0.00e+00	841.00
IUUC-Pab-097859	Pongo abelii	74.55	0.00e+00	797.00
IUUC-Pca-100344	Procavia capensis	70.27	0.00e+00	838.00
IUUC-Pva-103114	Pteropus vampyrus	50.23	1.00e-142	499.00
IUUC-Rno-105880	Rattus norvegicus	70.85	0.00e+00	825.00
IUUC-Sha-107015	Sarcophilus harrisii	76.34	0.00e+00	815.00
IUUC-Smo-109664	Selaginella moellendorffii	31.36	9.00e-36	144.00
IUUC-Sar-113397	Sorex araneus	83.29	0.00e+00	657.00
IUUC-Ssc-115988	Sus scrofa	63.35	3.00e-90	324.00
IUUC-Tgu-116717	Taeniopygia guttata	76.07	0.00e+00	800.00
IUUC-Tru-117805	Takifugu rubripes	68.03	0.00e+00	848.00
IUUC-Tsy-119442	Tarsius syrichta	69.01	0.00e+00	707.00
IUUC-Tni-119777	Tetraodon nigroviridis	70.11	2.00e-178	618.00
IUUC-Tbe-127322	Tupaia belangeri	54.22	1.00e-87	317.00
IUUC-Ttr-128181	Tursiops truncatus	74.65	0.00e+00	810.00
IUUC-Vpa-130483	Vicugna pacos	71.67	2.00e-160	558.00
IUUC-Xtr-132614	Xenopus tropicalis	68.72	0.00e+00	706.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence