iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Apl-003260

Ensembl Protein ID

ENSAPLP00000003261.1

UniProt Accession

U3I7P0; U3I7P0_ANAPL

Genbank Protein ID

ENSAPLP00000003261

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ADON01051822

Gene Name

KLHL2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAPLG00000003706.1	ENSAPLT00000003861.1	ENSAPLP00000003261.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	1.00e-21	76.8	47	114
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	2.30e-11	42.8	147	176

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgkldene 69
           +Dv++v ++ e+ ah++vLaa+S++F+a+f++e++es+  ++v ik+v+   +r l++++Yt +++ +e
   Q: 47   CDVTIVAEDMEIAAHRVVLAACSPYFHAMFTGEMSESR-AKRVRIKEVDGWTLRMLIDYIYTAEIQVTE 114
           8*************************************.*************************99765 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 2    eNclgilrfAdlydcpdLkdaaldfilkhF 31
            Nclgi++fAd++ c+dL  +a++++++hF
   Q: 147  VNCLGIRAFADMHACTDLLNKANTYAEQHF 176
           6***************************** PP

Organism

Anas platyrhynchos

Protein Sequence
(Fasta)

CTKLCHQKPL DLKDDNTEIH CPVTVNPWHM KKAFKVMNEL RSQNLLCDVT IVAEDMEIAA 60
HRVVLAACSP YFHAMFTGEM SESRAKRVRI KEVDGWTLRM LIDYIYTAEI QVTEENVQVL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCACCAAA CTTTGCCATC AGAAGCCCTT GGATCTGAAA GATGATAACA CTGAAATTCA 60
CTGTCCTGTT ACAGTGAATC CGTGGCACAT GAAGAAAGCT TTTAAAGTTA TGAATGAATT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR011043--Gal_Oxase/kelch_b-propeller
IPR015916--Gal_Oxidase_b-propeller
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0015629--C:actin cytoskeleton
GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0005737--C:cytoplasm
GO:0016567--P:protein ubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002378	Ailuropoda melanoleuca	92.98	0.00e+00	1106.00
IUUC-Aca-005143	Anolis carolinensis	88.70	0.00e+00	1092.00
IUUC-Cja-018942	Callithrix jacchus	92.98	0.00e+00	1108.00
IUUC-Cfa-020886	Canis familiaris	93.32	0.00e+00	1111.00
IUUC-Cpo-022543	Cavia porcellus	93.15	0.00e+00	1110.00
IUUC-Csa-023088	Chlorocebus sabaeus	93.32	0.00e+00	1110.00
IUUC-Dre-028082	Danio rerio	82.53	0.00e+00	988.00
IUUC-Dno-029873	Dasypus novemcinctus	90.99	0.00e+00	1086.00
IUUC-Dor-030460	Dipodomys ordii	74.14	0.00e+00	811.00
IUUC-Dse-031229	Dothistroma septosporum	33.72	4.00e-08	50.80
IUUC-Dme-032172	Drosophila melanogaster	61.54	0.00e+00	674.00
IUUC-Eca-033798	Equus caballus	92.47	0.00e+00	1105.00
IUUC-Eeu-034824	Erinaceus europaeus	85.45	0.00e+00	923.00
IUUC-Fca-036455	Felis catus	93.32	0.00e+00	1111.00
IUUC-Fal-037293	Ficedula albicollis	98.92	0.00e+00	1088.00
IUUC-Gmo-038811	Gadus morhua	78.67	0.00e+00	870.00
IUUC-Gga-040805	Gallus gallus	99.14	0.00e+00	1155.00
IUUC-Gac-041979	Gasterosteus aculeatus	80.77	0.00e+00	870.00
IUUC-Ggo-044620	Gorilla gorilla	88.18	0.00e+00	1047.00
IUUC-Hsa-046265	Homo sapiens	93.15	0.00e+00	1110.00
IUUC-Lch-049939	Latimeria chalumnae	83.90	0.00e+00	982.00
IUUC-Loc-052780	Lepisosteus oculatus	87.16	0.00e+00	1039.00
IUUC-Laf-053800	Loxodonta africana	93.15	0.00e+00	1110.00
IUUC-Mcc-055732	Macaca mulatta	92.28	0.00e+00	1097.00
IUUC-Meu-056011	Macropus eugenii	93.17	0.00e+00	1028.00
IUUC-Mmr-061067	Microcebus murinus	91.62	0.00e+00	1092.00
IUUC-Mdo-062977	Monodelphis domestica	92.47	0.00e+00	1101.00
IUUC-Mmu-064035	Mus musculus	92.19	0.00e+00	1087.00
IUUC-Mpu-066726	Mustela putorius furo	93.49	0.00e+00	1112.00
IUUC-Mlu-067020	Myotis lucifugus	92.98	0.00e+00	1107.00
IUUC-Nle-069456	Nomascus leucogenys	93.15	0.00e+00	1109.00
IUUC-Opr-071130	Ochotona princeps	83.56	0.00e+00	968.00
IUUC-Ont-072219	Oreochromis niloticus	81.34	0.00e+00	926.00
IUUC-Oan-073699	Ornithorhynchus anatinus	91.73	0.00e+00	944.00
IUUC-Ocu-074045	Oryctolagus cuniculus	92.98	0.00e+00	1107.00
IUUC-Oga-088494	Otolemur garnettii	92.98	0.00e+00	1108.00
IUUC-Oar-089645	Ovis aries	92.98	0.00e+00	1107.00
IUUC-Ptr-091063	Pan troglodytes	93.15	0.00e+00	1110.00
IUUC-Psi-093946	Pelodiscus sinensis	93.52	0.00e+00	1124.00
IUUC-Pma-094177	Petromyzon marinus	75.69	0.00e+00	799.00
IUUC-Pfo-096817	Poecilia formosa	80.65	0.00e+00	941.00
IUUC-Pab-097768	Pongo abelii	93.15	0.00e+00	1109.00
IUUC-Pca-100607	Procavia capensis	76.47	0.00e+00	778.00
IUUC-Pva-102218	Pteropus vampyrus	87.50	0.00e+00	1029.00
IUUC-Rno-105250	Rattus norvegicus	92.47	0.00e+00	1102.00
IUUC-Sar-113249	Sorex araneus	92.70	0.00e+00	1086.00
IUUC-Sre-115091	Sporisorium reilianum	53.12	6.00e-01	29.60
IUUC-Ssc-115423	Sus scrofa	92.98	0.00e+00	1108.00
IUUC-Tgu-117050	Taeniopygia guttata	98.12	0.00e+00	1144.00
IUUC-Tru-118239	Takifugu rubripes	80.20	0.00e+00	964.00
IUUC-Tsy-119377	Tarsius syrichta	79.62	0.00e+00	949.00
IUUC-Tni-120122	Tetraodon nigroviridis	81.01	0.00e+00	869.00
IUUC-Ttr-128574	Tursiops truncatus	93.77	0.00e+00	664.00
IUUC-Vpa-130707	Vicugna pacos	89.27	0.00e+00	836.00
IUUC-Xtr-132035	Xenopus tropicalis	85.64	0.00e+00	1042.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence