iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Aml-002107

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Putative uncharacterized protein

Genbank Nucleotide ID

ACTA01011920

Gene Name

UBE3B; PANDA_010178

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMEG00000016602.1	ENSAMET00000018265.1	ENSAMEP00000017552.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	2.00e-113	379.3	703	1068

Active Site

Position(s)	Description	Evidence
1036	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 2    ksdlkkrlevefvg.....EegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalq 83
           ++++k +++v+fv+     E+g+d++Gv++efl++++k++++p l+lf+++++d++ l+p+p+s++++ ++l+lFef+G++lgka++
   Q: 703  QHAMKGVIRVKFVNdlgvdEAGIDQDGVFKEFLEEIIKRVFDPALNLFKTTSGDER-LYPSPTSYIHE-NYLQLFEFVGKMLGKAVY 787
           7899********************************************99987665.59*******76.****************** PP
   S: 84   dgrlldlplsksfyklllgk.....klsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipV 165
           +g ++d+p++++f+++llg+       s+++l+++d+e+yk+l++ik++ + di +lgl+l++  +e+++g+  ++eL+pgG++ipV
   Q: 788  EGIVVDVPFASFFLSQLLGHhhsifYSSVDELPSLDSEFYKNLTSIKRY-DGDIADLGLTLSY--DEDVMGQLVCHELIPGGKTIPV 871
           ********************777777999********************.6788887777766..6999****************** PP
   S: 166  tneNkeeYvklvveyrlkegikeqveafreGfneviplellslFteeelellicGe.eeidvedlkketkykggytedspaiqwFwe 251
           tneNk +Y++l++++r++++ik+q++a+ +Gf+++i++e+ ++F++ el+ li+G+ +eid+edlkk+t y gg++ ++++i+w+w+
   Q: 872  TNENKISYIHLMAHFRMHTQIKNQTAALISGFRSIIKPEWTRMFSTPELQRLISGDnAEIDLEDLKKHTVYYGGFHGSHRVIIWLWD 958
           ********************************************************9****************************** PP
   S: 252  vl.eefsseerkafLqFvTgssrlPlgGfaelk........................prlfvirkdasddrlPssnTCfnyLkLPeY 313
           +l ++f+ +er++fL+FvT++sr Pl Gfa+lk                        + +f+irk +   rlP+s+TCfn+LkLP+Y
   Q: 959  ILaSDFTPDERAMFLKFVTSCSRPPLLGFAYLKppfsircvevsddqdtgdtlgsvlRGFFTIRKREPGGRLPTSSTCFNLLKLPNY 1045
           **99*************************************************************8888****************** PP
   S: 314  sskeilkekLlyAieetkgFels 336
           s+k++l+ekL+yAi++++gFels
   Q: 1046 SKKSVLREKLRYAISMNTGFELS 1068
           ********************985 PP

Organism

Ailuropoda melanoleuca

Protein Sequence
(Fasta)

MFTVSQTSRA WFIDRARQAR EERLVQKERE RAAVEIQAHV RSFLCRSRLQ REIRREIDEF 60
FKADDAESSK RSALCIFKIA RKLLFLFRIK EDNERFEKLC RCVLSSMDAE NEPKVWYVSL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTTCACCG TTTCTCAGAC CTCGAGAGCA TGGTTCATCG ATCGGGCCCG TCAGGCTCGA 60
GAGGAAAGGC TTGTGCAGAA GGAGCGGGAG CGGGCGGCTG TTGAGATCCA GGCCCACGTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000569--HECT_dom
IPR000048--IQ_motif_EF-hand-BS
IPR027401--Myosin-like_IQ_dom

PROSITE

PS50237--HECT
PS50096--IQ

Pfam

PF00632--HECT

SMART

SM00119--HECTc

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

KEGG

aml:100475409

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000128	Aegilops tauschii	36.09	2.00e-105	377.00
IUUC-Atr-003017	Amborella trichopoda	38.30	2.00e-109	390.00
IUUC-Apl-003328	Anas platyrhynchos	88.77	0.00e+00	1865.00
IUUC-Aly-005794	Arabidopsis lyrata	38.93	1.00e-108	388.00
IUUC-Ath-007269	Arabidopsis thaliana	39.29	3.00e-111	396.00
IUUC-Bta-013547	Bos taurus	96.44	0.00e+00	2114.00
IUUC-Bdi-014502	Brachypodium distachyon	38.97	3.00e-109	390.00
IUUC-Bol-015093	Brassica oleracea	40.00	1.00e-112	401.00
IUUC-Bra-016722	Brassica rapa	40.00	2.00e-113	403.00
IUUC-Cel-018447	Caenorhabditis elegans	38.04	0.00e+00	690.00
IUUC-Cja-019855	Callithrix jacchus	96.91	0.00e+00	2094.00
IUUC-Cfa-020066	Canis familiaris	98.49	0.00e+00	2115.00
IUUC-Cpo-021504	Cavia porcellus	95.32	0.00e+00	2085.00
IUUC-Csa-023579	Chlorocebus sabaeus	96.72	0.00e+00	2095.00
IUUC-Cho-024430	Choloepus hoffmanni	86.32	0.00e+00	1556.00
IUUC-Cin-025750	Ciona intestinalis	47.16	0.00e+00	971.00
IUUC-Csv-026016	Ciona savignyi	48.00	0.00e+00	1023.00
IUUC-Dre-028271	Danio rerio	81.68	0.00e+00	1765.00
IUUC-Dno-029054	Dasypus novemcinctus	96.82	0.00e+00	2097.00
IUUC-Dor-030938	Dipodomys ordii	88.11	0.00e+00	1872.00
IUUC-Dme-031602	Drosophila melanogaster	48.15	0.00e+00	967.00
IUUC-Ete-033041	Echinops telfairi	77.14	0.00e+00	1380.00
IUUC-Eca-034411	Equus caballus	97.57	0.00e+00	2088.00
IUUC-Eeu-035201	Erinaceus europaeus	85.34	0.00e+00	811.00
IUUC-Fca-036594	Felis catus	96.72	0.00e+00	2079.00
IUUC-Fal-037317	Ficedula albicollis	85.02	0.00e+00	1873.00
IUUC-Gmo-039412	Gadus morhua	77.56	0.00e+00	1725.00
IUUC-Gga-040149	Gallus gallus	88.69	0.00e+00	1900.00
IUUC-Gac-042088	Gasterosteus aculeatus	80.49	0.00e+00	1815.00
IUUC-Gma-042728	Glycine max	40.67	7.00e-111	395.00
IUUC-Ggo-045279	Gorilla gorilla	97.00	0.00e+00	2101.00
IUUC-Hsa-045660	Homo sapiens	96.72	0.00e+00	2095.00
IUUC-Hvu-047102	Hordeum vulgare	35.95	6.00e-105	375.00
IUUC-Itr-048021	Ictidomys tridecemlineatus	94.31	0.00e+00	1059.00
IUUC-Kpa-049307	Komagataella pastoris	32.29	4.00e-64	239.00
IUUC-Lch-050664	Latimeria chalumnae	82.73	0.00e+00	1831.00
IUUC-Lpe-050755	Leersia perrieri	37.04	3.00e-98	353.00
IUUC-Loc-052791	Lepisosteus oculatus	83.05	0.00e+00	1793.00
IUUC-Laf-053902	Loxodonta africana	97.19	0.00e+00	2109.00
IUUC-Mcc-054730	Macaca mulatta	96.63	0.00e+00	2095.00
IUUC-Meu-056527	Macropus eugenii	79.94	0.00e+00	1678.00
IUUC-Mtr-057671	Medicago truncatula	39.79	4.00e-111	396.00
IUUC-Mga-059260	Meleagris gallopavo	88.34	0.00e+00	1895.00
IUUC-Mmr-060804	Microcebus murinus	95.04	0.00e+00	2010.00
IUUC-Mdo-062575	Monodelphis domestica	84.13	0.00e+00	1795.00
IUUC-Mmu-063636	Mus musculus	91.68	0.00e+00	1939.00
IUUC-Mac-064989	Musa acuminata	39.36	8.00e-107	382.00
IUUC-Mpu-066677	Mustela putorius furo	98.21	0.00e+00	1999.00
IUUC-Mlu-067952	Myotis lucifugus	96.54	0.00e+00	2019.00
IUUC-Nle-069153	Nomascus leucogenys	96.91	0.00e+00	2095.00
IUUC-Opr-070554	Ochotona princeps	94.48	0.00e+00	1875.00
IUUC-Ont-071372	Oreochromis niloticus	81.67	0.00e+00	1795.00
IUUC-Oan-073327	Ornithorhynchus anatinus	71.78	0.00e+00	742.00
IUUC-Ocu-074183	Oryctolagus cuniculus	95.05	0.00e+00	2040.00
IUUC-Oba-075213	Oryza barthii	38.65	5.00e-106	379.00
IUUC-Obr-076320	Oryza brachyantha	34.95	5.00e-109	389.00
IUUC-Ogl-077093	Oryza glaberrima	38.82	1.00e-108	387.00
IUUC-Ogu-078947	Oryza glumaepatula	36.65	1.00e-108	388.00
IUUC-Oin-080058	Oryza indica	38.92	2.00e-108	387.00
IUUC-Olo-080742	Oryza longistaminata	38.65	2.00e-107	384.00
IUUC-Ome-081741	Oryza meridionalis	38.39	5.00e-101	362.00
IUUC-Oni-082385	Oryza nivara	36.65	1.00e-108	388.00
IUUC-Opu-083529	Oryza punctata	35.64	1.00e-108	387.00
IUUC-Oru-085128	Oryza rufipogon	37.18	5.00e-95	342.00
IUUC-Osa-085557	Oryza sativa	39.18	5.00e-108	385.00
IUUC-Ola-087337	Oryzias latipes	80.73	0.00e+00	1729.00
IUUC-Oga-088342	Otolemur garnettii	95.98	0.00e+00	1989.00
IUUC-Oar-090234	Ovis aries	96.50	0.00e+00	2088.00
IUUC-Ptr-091661	Pan troglodytes	97.00	0.00e+00	2100.00
IUUC-Pan-092728	Papio anubis	96.45	0.00e+00	2088.00
IUUC-Psi-093251	Pelodiscus sinensis	88.18	0.00e+00	1763.00
IUUC-Pma-094195	Petromyzon marinus	70.20	0.00e+00	1453.00
IUUC-Ppa-095544	Physcomitrella patens	37.87	1.00e-109	391.00
IUUC-Pfo-097472	Poecilia formosa	81.10	0.00e+00	1800.00
IUUC-Pab-098570	Pongo abelii	97.00	0.00e+00	2102.00
IUUC-Pca-100110	Procavia capensis	84.27	0.00e+00	1758.00
IUUC-Ppe-101281	Prunus persica	39.01	6.00e-107	382.00
IUUC-Pva-102887	Pteropus vampyrus	92.14	0.00e+00	1960.00
IUUC-Rno-106028	Rattus norvegicus	88.52	0.00e+00	1842.00
IUUC-Sha-107331	Sarcophilus harrisii	85.26	0.00e+00	1820.00
IUUC-Smo-109488	Selaginella moellendorffii	36.79	3.00e-105	376.00
IUUC-Sit-109811	Setaria italica	35.19	9.00e-110	391.00
IUUC-Sly-111013	Solanum lycopersicum	39.03	4.00e-102	366.00
IUUC-Sar-113287	Sorex araneus	85.71	0.00e+00	736.00
IUUC-Sbi-114433	Sorghum bicolor	35.09	2.00e-109	390.00
IUUC-Ssc-116103	Sus scrofa	97.47	0.00e+00	2080.00
IUUC-Tgu-117275	Taeniopygia guttata	88.22	0.00e+00	1883.00
IUUC-Tru-118681	Takifugu rubripes	80.17	0.00e+00	1810.00
IUUC-Tsy-118985	Tarsius syrichta	92.24	0.00e+00	1041.00
IUUC-Tni-120850	Tetraodon nigroviridis	91.48	0.00e+00	775.00
IUUC-Tca-121770	Theobroma cacao	39.01	5.00e-111	395.00
IUUC-Tae-125466	Triticum aestivum	36.51	6.00e-107	382.00
IUUC-Tur-126086	Triticum urartu	39.43	1.00e-104	375.00
IUUC-Tbe-127461	Tupaia belangeri	91.67	0.00e+00	1907.00
IUUC-Ttr-129269	Tursiops truncatus	96.82	0.00e+00	2066.00
IUUC-Vpa-130523	Vicugna pacos	78.27	2.00e-130	460.00
IUUC-Vvi-131524	Vitis vinifera	39.04	1.00e-108	388.00
IUUC-Xtr-132146	Xenopus tropicalis	84.14	0.00e+00	1850.00
IUUC-Xma-133526	Xiphophorus maculatus	81.01	0.00e+00	1796.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence