iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Loc-051754

Ensembl Protein ID

ENSLOCP00000014924.1

UniProt Accession

W5N2R5; W5N2R5_LEPOC

Genbank Protein ID

ENSLOCP00000014924

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AHAT01017300

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLOCG00000012128.1	ENSLOCT00000014953.1	ENSLOCP00000014924.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	5.50e-50	167.3	241	291

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 6    vqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFve 60
            ++lyd+ a +++eL ++ Gd++++i  ++ + gWl+g    +g+rG+fP+ Fv+
   Q: 241  GIALYDFRALESGELDFNVGDKIHII--NTLEDGWLEG--AVNGRRGIFPHRFVK 291
           579***********************..88899*****..8************98 PP

Organism

Lepisosteus oculatus

Protein Sequence
(Fasta)

MEPGSVVRAV FEFRPSVSEE LPLFTGDVIE VLSVVDEFWL LGNKDGVTGQ FPSTFVEPVT 60
IPNTKRGEKL YVCINDYSSL SAGNLLLQRG DVVVGEDTVD SNWLRGRNCW GSKGVFPLSC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTGATGAGCG ATGGAGCCGG GCTCTGTGGT GCGTGCCGTG TTCGAGTTCC GCCCCAGTGT 60
ATCTGAGGAG CTGCCCCTCT TCACCGGTGA CGTCATCGAG GTGCTCAGTG TGGTGGATGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR027267--AH/BAR-dom
IPR004148--BAR_dom
IPR000219--DH-domain
IPR001452--SH3_domain

PROSITE

PS51021--BAR
PS50010--DH_2
PS50002--SH3

Pfam

PF03114--BAR
PF00621--RhoGEF
PF00018--SH3_1
PF14604--SH3_9

SMART

SM00721--BAR
SM00325--RhoGEF
SM00326--SH3

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005089--F:Rho guanyl-nucleotide exchange factor activity
GO:0060271--P:cilium assembly
GO:0001822--P:kidney development
GO:0035023--P:regulation of Rho protein signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002128	Ailuropoda melanoleuca	60.39	0.00e+00	1002.00
IUUC-Apl-003934	Anas platyrhynchos	71.43	0.00e+00	929.00
IUUC-Aca-005005	Anolis carolinensis	54.28	0.00e+00	1350.00
IUUC-Ame-011361	Astyanax mexicanus	72.67	0.00e+00	1218.00
IUUC-Bta-013210	Bos taurus	61.80	0.00e+00	984.00
IUUC-Cel-018396	Caenorhabditis elegans	23.96	8.00e-31	130.00
IUUC-Cja-019104	Callithrix jacchus	59.15	0.00e+00	959.00
IUUC-Cfa-020960	Canis familiaris	60.09	0.00e+00	1009.00
IUUC-Cpo-022440	Cavia porcellus	60.74	0.00e+00	1014.00
IUUC-Csa-023391	Chlorocebus sabaeus	61.87	0.00e+00	1021.00
IUUC-Cho-024795	Choloepus hoffmanni	50.65	0.00e+00	769.00
IUUC-Cin-025137	Ciona intestinalis	37.95	2.00e-34	138.00
IUUC-Dre-027932	Danio rerio	70.28	0.00e+00	1166.00
IUUC-Dno-029750	Dasypus novemcinctus	60.78	0.00e+00	1011.00
IUUC-Dor-031109	Dipodomys ordii	64.16	0.00e+00	911.00
IUUC-Ete-032660	Echinops telfairi	61.13	0.00e+00	743.00
IUUC-Eca-033433	Equus caballus	61.03	0.00e+00	998.00
IUUC-Eeu-034929	Erinaceus europaeus	61.52	7.00e-127	449.00
IUUC-Fca-035859	Felis catus	60.39	0.00e+00	1023.00
IUUC-Fal-036653	Ficedula albicollis	52.15	0.00e+00	1394.00
IUUC-Gmo-038948	Gadus morhua	72.43	0.00e+00	967.00
IUUC-Gga-040279	Gallus gallus	60.02	0.00e+00	972.00
IUUC-Gac-041641	Gasterosteus aculeatus	66.49	0.00e+00	1153.00
IUUC-Hsa-046063	Homo sapiens	61.43	0.00e+00	1018.00
IUUC-Itr-049071	Ictidomys tridecemlineatus	56.13	0.00e+00	1015.00
IUUC-Lch-049865	Latimeria chalumnae	54.69	0.00e+00	1340.00
IUUC-Laf-054037	Loxodonta africana	49.22	0.00e+00	1407.00
IUUC-Mcc-055002	Macaca mulatta	62.15	0.00e+00	1025.00
IUUC-Meu-056420	Macropus eugenii	54.95	0.00e+00	829.00
IUUC-Mga-059868	Meleagris gallopavo	62.17	0.00e+00	975.00
IUUC-Mmr-060767	Microcebus murinus	62.32	0.00e+00	1040.00
IUUC-Mdo-061939	Monodelphis domestica	61.04	0.00e+00	994.00
IUUC-Mmu-063980	Mus musculus	57.89	0.00e+00	926.00
IUUC-Mpu-065913	Mustela putorius furo	61.04	0.00e+00	1049.00
IUUC-Mlu-067340	Myotis lucifugus	49.87	0.00e+00	1314.00
IUUC-Nle-069343	Nomascus leucogenys	61.21	0.00e+00	1010.00
IUUC-Opr-070694	Ochotona princeps	60.28	0.00e+00	1009.00
IUUC-Ont-071844	Oreochromis niloticus	67.40	0.00e+00	1124.00
IUUC-Oan-073605	Ornithorhynchus anatinus	60.00	2.00e-22	100.00
IUUC-Ocu-074406	Oryctolagus cuniculus	61.69	0.00e+00	1036.00
IUUC-Ola-087343	Oryzias latipes	65.60	0.00e+00	770.00
IUUC-Oga-088847	Otolemur garnettii	61.72	0.00e+00	1021.00
IUUC-Oar-089817	Ovis aries	59.84	0.00e+00	966.00
IUUC-Pan-092104	Papio anubis	61.87	0.00e+00	1015.00
IUUC-Psi-094045	Pelodiscus sinensis	41.81	7.00e-96	345.00
IUUC-Pma-094663	Petromyzon marinus	45.03	3.00e-137	483.00
IUUC-Pfo-096714	Poecilia formosa	62.47	0.00e+00	1112.00
IUUC-Pab-097918	Pongo abelii	61.39	0.00e+00	1015.00
IUUC-Pca-101096	Procavia capensis	43.02	0.00e+00	630.00
IUUC-Pva-102490	Pteropus vampyrus	60.26	0.00e+00	1021.00
IUUC-Rno-105908	Rattus norvegicus	58.18	0.00e+00	956.00
IUUC-Sha-107509	Sarcophilus harrisii	61.69	0.00e+00	1015.00
IUUC-Ssc-115250	Sus scrofa	60.18	0.00e+00	982.00
IUUC-Tru-118279	Takifugu rubripes	65.94	0.00e+00	1149.00
IUUC-Tni-120459	Tetraodon nigroviridis	75.62	0.00e+00	898.00
IUUC-Tbe-127753	Tupaia belangeri	56.38	2.00e-92	334.00
IUUC-Ttr-129096	Tursiops truncatus	58.17	0.00e+00	975.00
IUUC-Vpa-130643	Vicugna pacos	61.09	0.00e+00	764.00
IUUC-Xtr-131979	Xenopus tropicalis	51.75	0.00e+00	1512.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence