iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
RAID2
Protein-protein Interaction
IID
Post-translational Modifications (PTMs)
CPLM
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	97.56	0.00e+00	637.00	IUUC-Hsa-046501

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

MDHTDNELQG TNSSGSLGGL DVRRRIPIKL ISKQANKVKP APRTQRTVSR MPAKAAQGDE 60
EGFDYNEEQR YDCKGGELFG NQRRFPGHLF WDFKINILGE KDDTPVHFCD KCGLPIKVYG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTGTCCCCTC TCTTCCTGCC TCAGTCCTGC CTATGTGTGA CTCCCTCACC AAAGTCGGAT 60
GGTGCGGTTA GGAAGGGAAG CCAGTGAGAG CAGTCCCAGC GCACTTCCGC CTCTGCGCTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS00518--ZF_RING_1
PS50089--ZF_RING_2

Gene Ontology

GO:0016607--C:nuclear speck
GO:0003676--F:nucleic acid binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0007162--P:negative regulation of cell adhesion
GO:0030335--P:positive regulation of cell migration
GO:0045807--P:positive regulation of endocytosis
GO:0030155--P:regulation of cell adhesion
GO:0016337--P:single organismal cell-cell adhesion

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001549	Ailuropoda melanoleuca	93.65	2.00e-175	608.00
IUUC-Apl-003352	Anas platyrhynchos	87.14	6.00e-159	553.00
IUUC-Aca-005084	Anolis carolinensis	79.73	2.00e-143	502.00
IUUC-Bta-013383	Bos taurus	96.75	1.00e-179	622.00
IUUC-Bol-015734	Brassica oleracea	36.17	7.00e-13	69.30
IUUC-Cja-019505	Callithrix jacchus	97.96	0.00e+00	636.00
IUUC-Cfa-020255	Canis familiaris	97.15	0.00e+00	628.00
IUUC-Cpo-022545	Cavia porcellus	91.84	3.00e-144	504.00
IUUC-Cre-022922	Chlamydomonas reinhardtii	41.18	5.00e-06	45.80
IUUC-Csa-023318	Chlorocebus sabaeus	97.76	0.00e+00	633.00
IUUC-Cho-024701	Choloepus hoffmanni	91.10	5.00e-79	287.00
IUUC-Dre-028785	Danio rerio	55.27	9.00e-103	367.00
IUUC-Dor-030317	Dipodomys ordii	97.76	3.00e-175	608.00
IUUC-Eca-033554	Equus caballus	96.54	1.00e-179	622.00
IUUC-Fca-035864	Felis catus	96.51	2.00e-175	608.00
IUUC-Fal-037144	Ficedula albicollis	86.48	1.00e-154	539.00
IUUC-Gmo-039139	Gadus morhua	70.47	4.00e-79	288.00
IUUC-Gga-040912	Gallus gallus	86.41	8.00e-162	563.00
IUUC-Ggo-044818	Gorilla gorilla	97.56	0.00e+00	632.00
IUUC-Hsa-046501	Homo sapiens	97.56	0.00e+00	631.00
IUUC-Itr-048234	Ictidomys tridecemlineatus	98.17	0.00e+00	635.00
IUUC-Lch-049697	Latimeria chalumnae	83.37	3.00e-130	457.00
IUUC-Loc-052013	Lepisosteus oculatus	69.09	6.00e-126	444.00
IUUC-Laf-054485	Loxodonta africana	95.70	1.00e-168	585.00
IUUC-Mcc-054964	Macaca mulatta	53.35	3.00e-85	308.00
IUUC-Meu-056453	Macropus eugenii	59.55	3.00e-96	345.00
IUUC-Mga-060082	Meleagris gallopavo	86.06	8.00e-157	546.00
IUUC-Mmr-061363	Microcebus murinus	97.56	0.00e+00	630.00
IUUC-Mdo-062085	Monodelphis domestica	94.30	6.00e-176	610.00
IUUC-Mmu-063370	Mus musculus	99.39	0.00e+00	644.00
IUUC-Mpu-066221	Mustela putorius furo	96.54	2.00e-179	622.00
IUUC-Mlu-067612	Myotis lucifugus	96.54	2.00e-179	621.00
IUUC-Nle-069315	Nomascus leucogenys	97.01	7.00e-161	559.00
IUUC-Opr-070202	Ochotona princeps	94.44	1.00e-153	536.00
IUUC-Ont-071478	Oreochromis niloticus	60.00	5.00e-102	364.00
IUUC-Oan-073158	Ornithorhynchus anatinus	83.18	3.00e-130	458.00
IUUC-Ocu-074385	Oryctolagus cuniculus	96.65	2.00e-161	562.00
IUUC-Oin-079075	Oryza indica	34.04	1.00e-11	64.70
IUUC-Oni-083087	Oryza nivara	34.04	1.00e-11	64.70
IUUC-Opu-083232	Oryza punctata	34.04	5.00e-12	65.90
IUUC-Osa-085908	Oryza sativa	34.04	1.00e-11	64.70
IUUC-Oar-089223	Ovis aries	96.72	9.00e-177	612.00
IUUC-Ptr-091633	Pan troglodytes	97.56	0.00e+00	631.00
IUUC-Pan-092923	Papio anubis	96.95	1.00e-178	619.00
IUUC-Ppa-095417	Physcomitrella patens	37.62	9.00e-14	71.60
IUUC-Pfo-097005	Poecilia formosa	57.81	4.00e-90	325.00
IUUC-Pab-098077	Pongo abelii	97.50	4.00e-170	590.00
IUUC-Pgr-103634	Puccinia graminis	21.76	4.00e-06	44.70
IUUC-Sha-106599	Sarcophilus harrisii	93.89	9.00e-176	609.00
IUUC-Sar-113753	Sorex araneus	95.03	6.00e-146	510.00
IUUC-Sbi-114064	Sorghum bicolor	23.29	1.00e-03	38.90
IUUC-Ssc-116446	Sus scrofa	94.29	0.00e+00	651.00
IUUC-Tgu-117363	Taeniopygia guttata	86.31	1.00e-156	545.00
IUUC-Tru-118121	Takifugu rubripes	63.27	2.00e-114	405.00
IUUC-Tsy-119618	Tarsius syrichta	95.75	5.00e-122	431.00
IUUC-Tni-119858	Tetraodon nigroviridis	61.55	1.00e-103	369.00
IUUC-Ttr-129190	Tursiops truncatus	96.74	2.00e-180	624.00
IUUC-Vpa-130418	Vicugna pacos	47.74	4.00e-14	72.40
IUUC-Vvi-131653	Vitis vinifera	30.33	7.00e-15	75.50

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence