iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSDARG00000070470.6	ENSDART00000050559.6	ENSDARP00000050558.5
ENSDARG00000070470.6	ENSDART00000160292.1	ENSDARP00000132378.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	3.20e-08	34.9	25	66
UBD/SH3	7.20e-46	154.9	454	509

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C++Cle+++   +vlpC+H+f++ Cl  +      s++e rCP Cr
   Q: 25   CPVCLERLDATAKVLPCQHTFCRRCLLGI----VGSRGELRCPECR 66
           ********999**************9777....899*********8 PP

UBD/SH3

   S: 6    vqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
             ++++y++ ++deL+l+kG++ lv+ + +   gW kg++  +gk G+fP n++  ++
   Q: 454  YVAMFPYSPRKEDELELRKGEMFLVL-ERC-QDGWFKGTSMHTGKIGVFPGNYMSPVS 509
           6799**********************.555.569*******************99875 PP

Organism

Danio rerio

Protein Sequence
(Fasta)

MNEYAEKDCA SVKMDESALL DLLECPVCLE RLDATAKVLP CQHTFCRRCL LGIVGSRGEL 60
RCPECRTLVE SGVDELPSNI LLVRLLDGIK QRPRRTGSVH GTCANGSAVA GVRAQGAGGS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGCTGCGGTG TCCCACAGAA TCAACGCGGC TCGTCATGGC GCTCGGACGC AAGAACTCGC 60
TTCTCCTGTT TTTCTCTGCT TTCTTCTGAA TTGACTCCAT CTGACTCTCT TGGACTGGGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001452--SH3_domain
IPR028502--SH3RF1
IPR018957--Znf_C3HC4_RING-type
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50002--SH3
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF14604--SH3_9
PF00097--zf-C3HC4

PRINTS

PR00452--SH3DOMAIN

SMART

SM00184--RING
SM00326--SH3

Gene Ontology

GO:0008270--F:zinc ion binding
GO:0006915--P:apoptotic process
GO:0046328--P:regulation of JNK cascade

KEGG

dre:556523

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001528	Ailuropoda melanoleuca	61.79	0.00e+00	857.00
IUUC-Apl-003961	Anas platyrhynchos	62.25	0.00e+00	919.00
IUUC-Aca-004386	Anolis carolinensis	61.94	0.00e+00	879.00
IUUC-Ame-010659	Astyanax mexicanus	80.71	0.00e+00	1236.00
IUUC-Bta-012563	Bos taurus	66.67	3.00e-142	499.00
IUUC-Cja-019730	Callithrix jacchus	74.20	9.00e-149	521.00
IUUC-Cfa-020992	Canis familiaris	61.16	0.00e+00	890.00
IUUC-Cpo-021304	Cavia porcellus	60.33	0.00e+00	879.00
IUUC-Csa-023925	Chlorocebus sabaeus	75.27	2.00e-150	526.00
IUUC-Cho-024630	Choloepus hoffmanni	58.12	3.00e-108	386.00
IUUC-Cin-025274	Ciona intestinalis	46.77	3.00e-73	268.00
IUUC-Csv-026136	Ciona savignyi	43.85	1.00e-73	270.00
IUUC-Cme-027278	Cyanidioschyzon merolae	33.85	5.00e-07	50.10
IUUC-Dno-029083	Dasypus novemcinctus	68.17	0.00e+00	715.00
IUUC-Dor-030388	Dipodomys ordii	76.52	8.00e-145	508.00
IUUC-Dme-032207	Drosophila melanogaster	46.62	2.00e-66	248.00
IUUC-Ete-032809	Echinops telfairi	52.90	4.00e-142	498.00
IUUC-Eca-034185	Equus caballus	53.79	2.00e-108	386.00
IUUC-Eeu-034816	Erinaceus europaeus	67.74	1.00e-126	447.00
IUUC-Fca-036439	Felis catus	60.55	0.00e+00	881.00
IUUC-Fal-037074	Ficedula albicollis	62.84	0.00e+00	877.00
IUUC-Gmo-039443	Gadus morhua	69.52	4.00e-141	495.00
IUUC-Gga-040749	Gallus gallus	67.95	0.00e+00	733.00
IUUC-Gac-042360	Gasterosteus aculeatus	50.13	2.00e-97	350.00
IUUC-Ggo-045215	Gorilla gorilla	75.00	3.00e-150	526.00
IUUC-Hsa-046315	Homo sapiens	74.73	5.00e-150	525.00
IUUC-Itr-048409	Ictidomys tridecemlineatus	52.16	3.00e-103	369.00
IUUC-Lch-049453	Latimeria chalumnae	62.06	0.00e+00	763.00
IUUC-Loc-052248	Lepisosteus oculatus	35.61	1.00e-66	248.00
IUUC-Laf-053651	Loxodonta africana	74.46	5.00e-149	521.00
IUUC-Mcc-054688	Macaca mulatta	75.00	2.00e-150	526.00
IUUC-Meu-056291	Macropus eugenii	53.36	6.00e-147	514.00
IUUC-Mga-059944	Meleagris gallopavo	62.07	0.00e+00	904.00
IUUC-Mmr-061553	Microcebus murinus	76.61	3.00e-150	526.00
IUUC-Mdo-062313	Monodelphis domestica	58.99	0.00e+00	867.00
IUUC-Mmu-063516	Mus musculus	60.46	0.00e+00	901.00
IUUC-Mpu-066064	Mustela putorius furo	66.09	0.00e+00	699.00
IUUC-Mlu-067312	Myotis lucifugus	65.72	0.00e+00	706.00
IUUC-Nle-069035	Nomascus leucogenys	75.00	2.00e-150	526.00
IUUC-Opr-070690	Ochotona princeps	88.71	7.00e-64	238.00
IUUC-Ont-071484	Oreochromis niloticus	78.42	0.00e+00	1148.00
IUUC-Oan-073305	Ornithorhynchus anatinus	69.05	0.00e+00	746.00
IUUC-Ocu-074936	Oryctolagus cuniculus	76.34	2.00e-151	530.00
IUUC-Ola-086675	Oryzias latipes	73.21	0.00e+00	794.00
IUUC-Oga-087933	Otolemur garnettii	58.39	0.00e+00	698.00
IUUC-Oar-090408	Ovis aries	56.93	1.00e-178	619.00
IUUC-Ptr-090865	Pan troglodytes	75.00	2.00e-150	526.00
IUUC-Pan-092362	Papio anubis	75.00	7.00e-150	525.00
IUUC-Psi-093876	Pelodiscus sinensis	61.32	0.00e+00	892.00
IUUC-Pfo-097116	Poecilia formosa	77.35	0.00e+00	1149.00
IUUC-Pab-098127	Pongo abelii	75.00	3.00e-150	526.00
IUUC-Pca-100485	Procavia capensis	67.55	0.00e+00	708.00
IUUC-Pva-102661	Pteropus vampyrus	74.73	7.00e-148	518.00
IUUC-Pte-104349	Pyrenophora teres	25.58	8.00e-10	60.10
IUUC-Pyt-104695	Pyrenophora triticirepentis	26.36	3.00e-10	61.60
IUUC-Rno-105728	Rattus norvegicus	75.73	6.00e-149	521.00
IUUC-Sha-106515	Sarcophilus harrisii	66.72	0.00e+00	675.00
IUUC-Sar-113161	Sorex araneus	75.76	4.00e-144	505.00
IUUC-Ssc-115314	Sus scrofa	67.86	0.00e+00	685.00
IUUC-Tgu-117012	Taeniopygia guttata	65.24	0.00e+00	767.00
IUUC-Tru-118467	Takifugu rubripes	80.48	0.00e+00	763.00
IUUC-Tsy-119566	Tarsius syrichta	71.47	2.00e-133	470.00
IUUC-Tni-120830	Tetraodon nigroviridis	67.97	0.00e+00	775.00
IUUC-Tbe-128070	Tupaia belangeri	75.95	2.00e-149	523.00
IUUC-Ttr-128161	Tursiops truncatus	80.38	2.00e-116	413.00
IUUC-Vpa-130075	Vicugna pacos	68.03	1.00e-48	187.00
IUUC-Xtr-132628	Xenopus tropicalis	64.73	0.00e+00	727.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence