iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Tru-118467

UUCD1 version

UUC-TaR-00778

Ensembl Protein ID

ENSTRUP00000036599.1

UniProt Accession

H2UI28; H2UI28_TAKRU

Protein Name

Uncharacterized protein

Gene Name

sh3rf1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTRUG00000014310.1	ENSTRUT00000036728.1	ENSTRUP00000036597.1
ENSTRUG00000014310.1	ENSTRUT00000036729.1	ENSTRUP00000036598.1
ENSTRUG00000014310.1	ENSTRUT00000036730.1	ENSTRUP00000036599.1
ENSTRUG00000014310.1	ENSTRUT00000036731.1	ENSTRUP00000036600.1
ENSTRUG00000014310.1	ENSTRUT00000036732.1	ENSTRUP00000036601.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	4.30e-08	34.8	12	53
UBD/SH3	5.20e-45	152.5	598	653

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C++Cle+++   +vlpC+H+f++ Clq +      s++e rCP Cr
   Q: 12   CPVCLERLDASAKVLPCQHTFCRRCLQGI----LGSRGELRCPECR 53
           **********9***************999....99**********8 PP

UBD/SH3

   S: 6    vqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
             ++++y++ ++deL+l+kG++ lv+ + +   gW kg++  +gk G+fP n++  ++
   Q: 598  YVAMFPYTPRKEDELELRKGEMFLVL-ERC-QDGWFKGTSMHTGKIGVFPGNYMSPVS 653
           6799**********************.555.569*******************99875 PP

Organism

Takifugu rubripes

Protein Sequence
(Fasta)

MDESVLLDLL ECPVCLERLD ASAKVLPCQH TFCRRCLQGI LGSRGELRCP ECRTLVECAV 60
DELPSNILLV RLLDGIKQRP RKAGPGAGVC TNGTSGAVAR SHNSGTRDQG TPGTQPQRAQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAGAGAATGG ATGAATCTGT ACTGTTGGAC TTGCTCGAGT GCCCCGTGTG TCTCGAGCGG 60
CTGGACGCCT CGGCAAAAGT GCTCCCCTGT CAGCACACCT TTTGTCGCCG CTGTCTCCAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001452--SH3_domain
IPR028502--SH3RF1
IPR027370--Znf-RING_LisH
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50002--SH3
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF14604--SH3_9
PF13445--zf-RING_UBOX

PRINTS

PR00452--SH3DOMAIN

SMART

SM00184--RING
SM00326--SH3

Gene Ontology

GO:0008270--F:zinc ion binding
GO:0006915--P:apoptotic process
GO:0046328--P:regulation of JNK cascade

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001528	Ailuropoda melanoleuca	63.96	7.00e-153	534.00
IUUC-Apl-003961	Anas platyrhynchos	63.69	6.00e-169	587.00
IUUC-Aca-004386	Anolis carolinensis	57.27	0.00e+00	697.00
IUUC-Ame-010659	Astyanax mexicanus	73.71	0.00e+00	915.00
IUUC-Bta-012563	Bos taurus	77.12	2.00e-94	340.00
IUUC-Cja-019730	Callithrix jacchus	65.38	5.00e-152	531.00
IUUC-Cfa-020992	Canis familiaris	59.76	4.00e-153	535.00
IUUC-Cpo-021304	Cavia porcellus	78.28	5.00e-103	369.00
IUUC-Csa-023925	Chlorocebus sabaeus	64.51	9.00e-151	527.00
IUUC-Cho-024630	Choloepus hoffmanni	55.99	5.00e-106	379.00
IUUC-Cin-025274	Ciona intestinalis	50.57	9.00e-45	173.00
IUUC-Csv-026136	Ciona savignyi	45.41	4.00e-46	178.00
IUUC-Cme-027278	Cyanidioschyzon merolae	38.30	4.00e-06	46.60
IUUC-Dre-028290	Danio rerio	79.09	0.00e+00	790.00
IUUC-Dno-029083	Dasypus novemcinctus	63.55	1.00e-153	537.00
IUUC-Dor-030388	Dipodomys ordii	77.87	3.00e-97	349.00
IUUC-Dme-032207	Drosophila melanogaster	46.92	1.00e-34	141.00
IUUC-Ete-032809	Echinops telfairi	54.18	5.00e-139	488.00
IUUC-Eca-034185	Equus caballus	63.22	8.00e-155	540.00
IUUC-Eeu-034816	Erinaceus europaeus	64.75	1.00e-77	284.00
IUUC-Fal-037074	Ficedula albicollis	66.00	2.00e-159	556.00
IUUC-Gmo-039443	Gadus morhua	68.38	3.00e-141	496.00
IUUC-Gga-040749	Gallus gallus	66.33	6.00e-164	571.00
IUUC-Gac-041420	Gasterosteus aculeatus	75.94	0.00e+00	671.00
IUUC-Ggo-045215	Gorilla gorilla	62.85	5.00e-151	528.00
IUUC-Hsa-046315	Homo sapiens	62.66	2.00e-151	529.00
IUUC-Lch-049453	Latimeria chalumnae	64.85	4.00e-169	588.00
IUUC-Laf-053651	Loxodonta africana	56.76	0.00e+00	647.00
IUUC-Mcc-054688	Macaca mulatta	64.26	3.00e-150	525.00
IUUC-Meu-056291	Macropus eugenii	49.64	2.00e-128	453.00
IUUC-Mga-059944	Meleagris gallopavo	63.62	4.00e-170	591.00
IUUC-Mmr-061553	Microcebus murinus	64.49	4.00e-148	518.00
IUUC-Mdo-062313	Monodelphis domestica	54.91	2.00e-180	626.00
IUUC-Mmu-063516	Mus musculus	60.49	1.00e-159	556.00
IUUC-Mpu-066064	Mustela putorius furo	62.85	3.00e-152	532.00
IUUC-Mlu-067312	Myotis lucifugus	65.38	4.00e-148	518.00
IUUC-Nle-069035	Nomascus leucogenys	64.40	5.00e-151	528.00
IUUC-Opr-070690	Ochotona princeps	88.71	3.00e-63	236.00
IUUC-Ont-071484	Oreochromis niloticus	83.58	0.00e+00	1034.00
IUUC-Oan-073305	Ornithorhynchus anatinus	65.99	4.00e-159	555.00
IUUC-Ocu-074936	Oryctolagus cuniculus	64.74	6.00e-155	541.00
IUUC-Ola-086675	Oryzias latipes	77.90	0.00e+00	666.00
IUUC-Oga-087933	Otolemur garnettii	60.62	2.00e-152	532.00
IUUC-Oar-090408	Ovis aries	60.11	3.00e-137	482.00
IUUC-Ptr-090865	Pan troglodytes	62.29	1.00e-150	527.00
IUUC-Pan-092362	Papio anubis	64.51	5.00e-150	525.00
IUUC-Psi-093876	Pelodiscus sinensis	61.57	2.00e-160	559.00
IUUC-Ppa-095766	Physcomitrella patens	38.89	3.00e-07	48.50
IUUC-Pfo-097116	Poecilia formosa	82.63	0.00e+00	1039.00
IUUC-Pab-098127	Pongo abelii	62.92	4.00e-151	528.00
IUUC-Pca-100485	Procavia capensis	65.14	2.00e-152	533.00
IUUC-Pva-102661	Pteropus vampyrus	64.02	3.00e-147	515.00
IUUC-Rno-105728	Rattus norvegicus	62.05	3.00e-147	515.00
IUUC-Sha-106515	Sarcophilus harrisii	65.81	6.00e-143	501.00
IUUC-Sar-113161	Sorex araneus	77.87	2.00e-93	337.00
IUUC-Ssc-115314	Sus scrofa	64.85	2.00e-147	516.00
IUUC-Tgu-117012	Taeniopygia guttata	63.09	2.00e-169	589.00
IUUC-Tsy-119566	Tarsius syrichta	73.61	5.00e-102	365.00
IUUC-Tni-120830	Tetraodon nigroviridis	80.26	0.00e+00	759.00
IUUC-Tbe-128070	Tupaia belangeri	78.28	1.00e-101	364.00
IUUC-Ttr-128161	Tursiops truncatus	88.06	2.00e-65	244.00
IUUC-Vpa-130075	Vicugna pacos	67.21	6.00e-48	185.00
IUUC-Xtr-132628	Xenopus tropicalis	61.86	1.00e-154	540.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence