iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Fal-037106

Ensembl Protein ID

ENSFALP00000000746.1

UniProt Accession

U3JD92; U3JD92_FICAL

Genbank Protein ID

ENSFALP00000000746

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGTO01001442

Gene Name

IFIH1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFALG00000000721.1	ENSFALT00000000750.1	ENSFALP00000000746.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/CARD	2.40e-17	62.9	116	188

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/CARD

   S: 2    deeyrlllstlqdrvrklLdvtdvldkylseflleeekel.ilaaaetkgnmqaaelLLktLvqkegWfrefl 73
           ++  ++l+++l  ++++++   +v +k+l+    + e+   i+    + gn ++a++LL+++vqk+ Wf+ fl
   Q: 116  HDLCVQLVQLLHGTLVDRMRALQVAGKCLEMGIFQDEDMDrIQTVTDNRGNRDGARELLSRIVQKKDWFSSFL 188
           57889************************98666666655055556899*********************996 PP

Organism

Ficedula albicollis

Protein Sequence
(Fasta)

GVRAAAMAEG TRDERFLYMI SCFRPRLKQF IQVQPVLDRL PSLSAEDRDR VRAAAEQRGA 60
AAGAEELLRA LERGPRGRGR PREFLQALEQ GGCGLAACYA NPSLSLLPSP AQEAEHDLCV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGGGTTCGCG CTGCCGCCAT GGCAGAGGGC ACCCGGGACG AGCGGTTCCT CTACATGATC 60
TCGTGCTTCA GGCCGCGGCT GAAGCAGTTC ATCCAGGTGC AGCCCGTGCT GGACCGGCTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome

Interpro

IPR031964--CARD_dom
IPR011029--DEATH-like_dom
IPR006935--Helicase/UvrB_N
IPR014001--Helicase_ATP-bd
IPR001650--Helicase_C
IPR027417--P-loop_NTPase
IPR021673--RLR_CTR

PROSITE

PS51192--HELICASE_ATP_BIND_1
PS51194--HELICASE_CTER
PS51789--RLR_CTR

Pfam

PF16739--CARD_2
PF00271--Helicase_C
PF04851--ResIII
PF11648--RIG-I_C-RD

SMART

SM00487--DEXDc
SM00490--HELICc

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005524--F:ATP binding
GO:0003677--F:DNA binding
GO:0003725--F:double-stranded RNA binding
GO:0016817--F:hydrolase activity, acting on acid anhydrides
GO:0043021--F:ribonucleoprotein complex binding
GO:0003727--F:single-stranded RNA binding
GO:0008270--F:zinc ion binding
GO:0045087--P:innate immune response
GO:0039530--P:MDA-5 signaling pathway
GO:0032727--P:positive regulation of interferon-alpha production
GO:0032728--P:positive regulation of interferon-beta production
GO:0016925--P:protein sumoylation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001336	Ailuropoda melanoleuca	59.83	0.00e+00	1119.00
IUUC-Apl-003900	Anas platyrhynchos	80.31	0.00e+00	1571.00
IUUC-Aca-005329	Anolis carolinensis	63.33	0.00e+00	1144.00
IUUC-Ame-011305	Astyanax mexicanus	49.46	0.00e+00	879.00
IUUC-Bta-012361	Bos taurus	59.92	0.00e+00	1095.00
IUUC-Bdi-014006	Brachypodium distachyon	21.23	5.20e-01	30.00
IUUC-Cja-018760	Callithrix jacchus	59.38	0.00e+00	1064.00
IUUC-Cfa-020321	Canis familiaris	59.42	0.00e+00	1103.00
IUUC-Cpo-022450	Cavia porcellus	59.51	0.00e+00	1104.00
IUUC-Cre-022916	Chlamydomonas reinhardtii	29.06	4.00e-10	60.50
IUUC-Csa-024194	Chlorocebus sabaeus	60.73	0.00e+00	1083.00
IUUC-Cho-024364	Choloepus hoffmanni	55.20	0.00e+00	764.00
IUUC-Dre-028305	Danio rerio	55.57	0.00e+00	733.00
IUUC-Dno-029831	Dasypus novemcinctus	60.00	0.00e+00	1133.00
IUUC-Dor-030410	Dipodomys ordii	66.17	0.00e+00	815.00
IUUC-Ete-032950	Echinops telfairi	61.57	8.00e-150	524.00
IUUC-Eca-034279	Equus caballus	60.64	0.00e+00	1121.00
IUUC-Eeu-034678	Erinaceus europaeus	58.30	0.00e+00	1092.00
IUUC-Fca-035618	Felis catus	64.56	0.00e+00	725.00
IUUC-Fso-038398	Fusarium solani	28.31	4.00e-32	133.00
IUUC-Gmo-038598	Gadus morhua	51.91	0.00e+00	719.00
IUUC-Gga-040467	Gallus gallus	82.24	0.00e+00	1607.00
IUUC-Gac-042316	Gasterosteus aculeatus	47.57	0.00e+00	851.00
IUUC-Ggo-045461	Gorilla gorilla	60.54	0.00e+00	1077.00
IUUC-Hsa-045771	Homo sapiens	60.35	0.00e+00	1071.00
IUUC-Itr-048762	Ictidomys tridecemlineatus	59.00	0.00e+00	1099.00
IUUC-Lch-049913	Latimeria chalumnae	65.80	0.00e+00	952.00
IUUC-Loc-052768	Lepisosteus oculatus	53.54	0.00e+00	996.00
IUUC-Laf-053933	Loxodonta africana	59.79	0.00e+00	1091.00
IUUC-Mcc-054695	Macaca mulatta	60.73	0.00e+00	1087.00
IUUC-Meu-056829	Macropus eugenii	62.07	0.00e+00	943.00
IUUC-Mga-059205	Meleagris gallopavo	81.70	0.00e+00	1603.00
IUUC-Mvi-060497	Microbotryum violaceum	32.59	2.00e-15	78.60
IUUC-Mmr-060703	Microcebus murinus	59.78	0.00e+00	1090.00
IUUC-Mdo-063079	Monodelphis domestica	60.65	0.00e+00	1177.00
IUUC-Mmu-064066	Mus musculus	59.40	0.00e+00	1129.00
IUUC-Mpu-066261	Mustela putorius furo	59.15	0.00e+00	1116.00
IUUC-Mlu-068196	Myotis lucifugus	58.58	0.00e+00	1074.00
IUUC-Nle-069479	Nomascus leucogenys	59.63	0.00e+00	1072.00
IUUC-Opr-070717	Ochotona princeps	54.62	0.00e+00	773.00
IUUC-Ont-071702	Oreochromis niloticus	48.51	0.00e+00	885.00
IUUC-Oan-073639	Ornithorhynchus anatinus	60.87	0.00e+00	1051.00
IUUC-Ocu-074521	Oryctolagus cuniculus	59.51	0.00e+00	1113.00
IUUC-Ola-086351	Oryzias latipes	46.35	0.00e+00	787.00
IUUC-Oga-088539	Otolemur garnettii	58.24	0.00e+00	1089.00
IUUC-Oar-090186	Ovis aries	60.16	0.00e+00	1087.00
IUUC-Ptr-090575	Pan troglodytes	59.24	0.00e+00	1064.00
IUUC-Pan-092371	Papio anubis	60.83	0.00e+00	1087.00
IUUC-Psi-093072	Pelodiscus sinensis	73.58	0.00e+00	1474.00
IUUC-Pma-094345	Petromyzon marinus	44.36	4.00e-99	354.00
IUUC-Pfo-096401	Poecilia formosa	53.78	0.00e+00	711.00
IUUC-Pab-097623	Pongo abelii	60.06	0.00e+00	1063.00
IUUC-Pca-100993	Procavia capensis	53.46	0.00e+00	876.00
IUUC-Pva-102227	Pteropus vampyrus	56.31	0.00e+00	1006.00
IUUC-Pgr-103529	Puccinia graminis	30.80	1.00e-15	79.00
IUUC-Rno-105198	Rattus norvegicus	58.54	0.00e+00	1099.00
IUUC-Sha-107622	Sarcophilus harrisii	61.78	0.00e+00	1191.00
IUUC-Sar-113625	Sorex araneus	68.10	5.00e-126	445.00
IUUC-Tgu-117486	Taeniopygia guttata	88.14	0.00e+00	1689.00
IUUC-Tru-118445	Takifugu rubripes	46.12	0.00e+00	831.00
IUUC-Tsy-119512	Tarsius syrichta	58.08	0.00e+00	1013.00
IUUC-Tni-120711	Tetraodon nigroviridis	45.96	0.00e+00	832.00
IUUC-Tre-122194	Trichoderma reesei	24.87	2.00e-19	91.70
IUUC-Tbe-127644	Tupaia belangeri	52.74	0.00e+00	956.00
IUUC-Ttr-128989	Tursiops truncatus	54.73	0.00e+00	1019.00
IUUC-Vpa-130587	Vicugna pacos	56.69	0.00e+00	910.00
IUUC-Xtr-132127	Xenopus tropicalis	51.90	0.00e+00	1008.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence