iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Nle-069973

Ensembl Protein ID

ENSNLEP00000014913.1

UniProt Accession

G1RNU9; G1RNU9_NOMLE

Genbank Protein ID

ENSNLEP00000014913

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ADFV01176106

Gene Name

OPTN

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSNLEG00000012276.2	ENSNLET00000015658.2	ENSNLEP00000014913.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/Alpha-Helix/UBAN	1.10e-25	89.4	454	513

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/UBAN

   S: 1    keelletvevLkqQveiYkeDFqaERadRErlneekeeLqeqveklqkqvsklndslkas 60
           +ee+let++vL++Q+e+Y++DF+aERa+RE+++e+ke+L+ q+++l+k++++++d++++s
   Q: 454  QEEDLETMTVLRAQMEVYCSDFHAERAAREKIHEQKEQLALQLAVLLKENDAFEDGGRQS 513
           79********************************************************98 PP

Organism

Nomascus leucogenys

Protein Sequence
(Fasta)

MSHQPLSCLT EKGDSPSEST GNGPPHLAHP NLDTFTPEEL LQQMKELLTE NHQLKEAMKL 60
NNQAMKGRFE ELSAWTEKQK EERQFFEIQS KEAKERLMAL SHENEKLKEE LGKLKGKSER 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCCTTGTGGG GCGGGGGACA GCTCTATTTT CAACAGGTGA CTTTTCCACA GGAACTTCTG 60
CAATGTCCCA TCAACCTCTC AGCTGCCTCA CTGAAAAGGG GGACAGCCCC AGTGAAAGCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR032419--CC2-LZ_dom
IPR021063--NEMO_N
IPR032939--Optineurin
IPR034735--ZF_CCHC_NOA

PROSITE

PS51801--ZF_CCHC_NOA

Pfam

PF16516--CC2-LZ
PF11577--NEMO

Gene Ontology

GO:0031410--C:cytoplasmic vesicle
GO:0005829--C:cytosol
GO:0005802--C:trans-Golgi network
GO:0050829--P:defense response to Gram-negative bacterium
GO:0090161--P:Golgi ribbon formation
GO:0043001--P:Golgi to plasma membrane protein transport
GO:0016236--P:macroautophagy
GO:0001920--P:negative regulation of receptor recycling
GO:0061734--P:parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization
GO:1904417--P:positive regulation of xenophagy
GO:0000042--P:protein targeting to Golgi

KEGG

nle:100597487

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002037	Ailuropoda melanoleuca	80.94	0.00e+00	779.00
IUUC-Apl-003812	Anas platyrhynchos	56.16	2.00e-147	515.00
IUUC-Aca-004625	Anolis carolinensis	55.71	3.00e-147	514.00
IUUC-Aly-005781	Arabidopsis lyrata	55.00	2.00e-02	33.50
IUUC-Ame-011116	Astyanax mexicanus	37.48	1.00e-70	260.00
IUUC-Bta-013240	Bos taurus	82.76	0.00e+00	891.00
IUUC-Cja-019911	Callithrix jacchus	93.41	0.00e+00	962.00
IUUC-Cfa-020330	Canis familiaris	84.83	0.00e+00	844.00
IUUC-Cpo-021753	Cavia porcellus	80.96	0.00e+00	817.00
IUUC-Csa-023662	Chlorocebus sabaeus	96.53	0.00e+00	985.00
IUUC-Cho-024574	Choloepus hoffmanni	67.68	8.00e-128	449.00
IUUC-Cme-027299	Cyanidioschyzon merolae	35.96	2.00e-03	37.00
IUUC-Dre-027720	Danio rerio	40.21	2.00e-90	326.00
IUUC-Dno-029079	Dasypus novemcinctus	79.48	0.00e+00	772.00
IUUC-Dor-030890	Dipodomys ordii	81.72	0.00e+00	837.00
IUUC-Ete-032568	Echinops telfairi	81.14	0.00e+00	744.00
IUUC-Eca-033528	Equus caballus	83.76	0.00e+00	845.00
IUUC-Eeu-035219	Erinaceus europaeus	74.44	0.00e+00	808.00
IUUC-Fca-035852	Felis catus	83.95	0.00e+00	838.00
IUUC-Fal-036862	Ficedula albicollis	58.57	2.00e-145	509.00
IUUC-Gmo-038735	Gadus morhua	40.22	1.00e-74	273.00
IUUC-Gga-040939	Gallus gallus	55.69	6.00e-148	517.00
IUUC-Gac-041580	Gasterosteus aculeatus	42.66	5.00e-95	341.00
IUUC-Ggo-045034	Gorilla gorilla	86.14	0.00e+00	909.00
IUUC-Hsa-046624	Homo sapiens	96.71	0.00e+00	1025.00
IUUC-Itr-048288	Ictidomys tridecemlineatus	78.18	0.00e+00	809.00
IUUC-Lch-049720	Latimeria chalumnae	49.87	4.00e-82	298.00
IUUC-Loc-052185	Lepisosteus oculatus	46.05	6.00e-104	371.00
IUUC-Laf-054079	Loxodonta africana	82.32	0.00e+00	821.00
IUUC-Mcc-055674	Macaca mulatta	95.84	0.00e+00	960.00
IUUC-Meu-056769	Macropus eugenii	55.42	5.00e-76	278.00
IUUC-Mga-060203	Meleagris gallopavo	56.36	7.00e-141	493.00
IUUC-Mmr-061492	Microcebus murinus	86.21	0.00e+00	851.00
IUUC-Mdo-063051	Monodelphis domestica	74.79	0.00e+00	788.00
IUUC-Mmu-063409	Mus musculus	76.65	0.00e+00	849.00
IUUC-Mpu-065907	Mustela putorius furo	78.11	0.00e+00	810.00
IUUC-Mlu-066957	Myotis lucifugus	82.76	0.00e+00	789.00
IUUC-Opr-071049	Ochotona princeps	79.10	0.00e+00	751.00
IUUC-Ont-071915	Oreochromis niloticus	43.53	8.00e-93	334.00
IUUC-Oan-072965	Ornithorhynchus anatinus	72.68	0.00e+00	760.00
IUUC-Ocu-074029	Oryctolagus cuniculus	75.70	0.00e+00	691.00
IUUC-Ola-087019	Oryzias latipes	41.21	2.00e-88	319.00
IUUC-Oga-088613	Otolemur garnettii	87.95	0.00e+00	899.00
IUUC-Oar-090386	Ovis aries	82.41	0.00e+00	884.00
IUUC-Ptr-091619	Pan troglodytes	96.53	0.00e+00	1022.00
IUUC-Pan-092178	Papio anubis	95.52	0.00e+00	962.00
IUUC-Psi-093214	Pelodiscus sinensis	63.21	5.00e-168	583.00
IUUC-Pfo-096901	Poecilia formosa	41.20	1.00e-84	306.00
IUUC-Pab-097560	Pongo abelii	87.69	0.00e+00	882.00
IUUC-Pca-100853	Procavia capensis	76.81	7.00e-130	457.00
IUUC-Pva-102255	Pteropus vampyrus	83.77	0.00e+00	791.00
IUUC-Rno-105812	Rattus norvegicus	79.39	0.00e+00	849.00
IUUC-Sha-107225	Sarcophilus harrisii	79.14	6.00e-156	543.00
IUUC-Sar-113736	Sorex araneus	73.22	1.00e-128	453.00
IUUC-Ssc-115422	Sus scrofa	83.62	0.00e+00	877.00
IUUC-Tgu-116924	Taeniopygia guttata	59.13	7.00e-147	513.00
IUUC-Tru-117695	Takifugu rubripes	38.45	3.00e-88	318.00
IUUC-Tsy-119090	Tarsius syrichta	86.59	3.00e-160	557.00
IUUC-Tni-120645	Tetraodon nigroviridis	41.74	1.00e-92	333.00
IUUC-Tbe-127970	Tupaia belangeri	69.08	0.00e+00	669.00
IUUC-Ttr-129244	Tursiops truncatus	83.07	0.00e+00	823.00
IUUC-Vpa-130313	Vicugna pacos	81.69	0.00e+00	788.00
IUUC-Xtr-132115	Xenopus tropicalis	45.07	2.00e-101	362.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence