iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Laf-054046

Ensembl Protein ID

ENSLAFP00000004572.4

UniProt Accession

G3SW93; G3SW93_LOXAF

Protein Name

Uncharacterized protein

Gene Name

NSD1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000005450.4	ENSLAFT00000032567.1	ENSLAFP00000022951.1
ENSLAFG00000005450.4	ENSLAFT00000005453.4	ENSLAFP00000004572.4
ENSLAFG00000005450.4	ENSLAFT00000034875.1	ENSLAFP00000022032.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	7.90e-17	61.6	1359	1399

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 3    vClvCgeggedekslveCekCrewfHpaClklsveeelpnsekwiCpkCr 52
           +C vC egg+    l++C+ C  +fH +Cl++      p+ + w+C++C+
   Q: 1359 WCFVCSEGGS----LLCCDSCPAAFHRECLNID----IPEGN-WYCNDCK 1399
           8*********....*******************....99996.******8 PP

Organism

Loxodonta africana

Protein Sequence
(Fasta)

VSNRRPYRQY YVEAFGDPSE RAWVAGKAIV MFEGRHQFEE LPVLRRRGKQ KEKGYRHKVP 60
QKILSKWEAS VGLAEQYDVP KGPKNRKCVR SSIKLDSEED MPFEDCTNDP ESEHDLLLNG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGATCAGA CCTGTGAACT ACCCAGAAGA AATTGCCTGC TGCCCTTTTC CAATCCAGTG 60
AATTTAGATG CCCCAGAAGA CAAGGACAGC CCTTTCGGTA ATGGTCAATC CAATTTTTCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0489--Methyltransferase
KW-1185--Reference proteome
KW-0949--S-adenosyl-L-methionine
KW-0808--Transferase
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR006560--AWS_dom
IPR003616--Post-SET_dom
IPR000313--PWWP_dom
IPR001214--SET_dom
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51215--AWS
PS50868--POST_SET
PS50812--PWWP
PS50280--SET
PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF00855--PWWP
PF00856--SET

SMART

SM00570--AWS
SM00249--PHD
SM00508--PostSET
SM00293--PWWP
SM00317--SET

Gene Ontology

GO:0005634--C:nucleus
GO:0046975--F:histone methyltransferase activity (H3-K36 specific)
GO:0000979--F:RNA polymerase II core promoter sequence-specific DNA binding
GO:0003712--F:transcription cofactor activity
GO:0008270--F:zinc ion binding
GO:0045893--P:positive regulation of transcription, DNA-templated
GO:0000414--P:regulation of histone H3-K36 methylation
GO:0033135--P:regulation of peptidyl-serine phosphorylation
GO:1903025--P:regulation of RNA polymerase II regulatory region sequence-specific DNA binding

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001795	Ailuropoda melanoleuca	90.56	0.00e+00	4109.00
IUUC-Apl-003953	Anas platyrhynchos	57.73	0.00e+00	2205.00
IUUC-Aca-005339	Anolis carolinensis	51.57	0.00e+00	1767.00
IUUC-Bta-012966	Bos taurus	90.13	0.00e+00	4155.00
IUUC-Bdi-014781	Brachypodium distachyon	30.58	7.00e-13	69.30
IUUC-Bol-016001	Brassica oleracea	32.70	2.00e-16	81.60
IUUC-Bra-017864	Brassica rapa	32.08	5.00e-15	77.40
IUUC-Cja-018780	Callithrix jacchus	89.10	0.00e+00	3775.00
IUUC-Cfa-020975	Canis familiaris	90.05	0.00e+00	4076.00
IUUC-Cpo-021331	Cavia porcellus	86.71	0.00e+00	2680.00
IUUC-Csa-024226	Chlorocebus sabaeus	89.46	0.00e+00	4009.00
IUUC-Cho-024464	Choloepus hoffmanni	76.79	0.00e+00	1417.00
IUUC-Dre-028152	Danio rerio	62.55	0.00e+00	1256.00
IUUC-Dno-029230	Dasypus novemcinctus	88.25	0.00e+00	3949.00
IUUC-Dor-031016	Dipodomys ordii	81.29	0.00e+00	1308.00
IUUC-Dme-032193	Drosophila melanogaster	36.87	3.00e-122	433.00
IUUC-Eca-033591	Equus caballus	89.71	0.00e+00	4113.00
IUUC-Fca-035791	Felis catus	90.30	0.00e+00	4204.00
IUUC-Fal-037378	Ficedula albicollis	57.30	0.00e+00	2088.00
IUUC-Gmo-038919	Gadus morhua	71.20	0.00e+00	933.00
IUUC-Gga-040881	Gallus gallus	58.26	0.00e+00	2116.00
IUUC-Gac-041378	Gasterosteus aculeatus	77.71	0.00e+00	1068.00
IUUC-Hsa-046436	Homo sapiens	89.71	0.00e+00	4042.00
IUUC-Itr-048194	Ictidomys tridecemlineatus	88.57	0.00e+00	4081.00
IUUC-Lch-049684	Latimeria chalumnae	50.50	0.00e+00	1545.00
IUUC-Mcc-055593	Macaca mulatta	89.33	0.00e+00	4015.00
IUUC-Mga-059756	Meleagris gallopavo	56.85	0.00e+00	2183.00
IUUC-Mmr-061182	Microcebus murinus	88.56	0.00e+00	4052.00
IUUC-Mdo-061984	Monodelphis domestica	68.50	0.00e+00	2982.00
IUUC-Mmu-063605	Mus musculus	81.28	0.00e+00	3663.00
IUUC-Mpu-066446	Mustela putorius furo	89.96	0.00e+00	4158.00
IUUC-Mlu-067261	Myotis lucifugus	88.19	0.00e+00	4012.00
IUUC-Nle-069818	Nomascus leucogenys	89.71	0.00e+00	4044.00
IUUC-Opr-070842	Ochotona princeps	82.44	0.00e+00	2312.00
IUUC-Ont-072448	Oreochromis niloticus	75.67	0.00e+00	1147.00
IUUC-Oan-073496	Ornithorhynchus anatinus	74.75	0.00e+00	1664.00
IUUC-Ocu-074918	Oryctolagus cuniculus	88.69	0.00e+00	4110.00
IUUC-Obr-076753	Oryza brachyantha	54.84	1.00e-07	53.10
IUUC-Opu-083371	Oryza punctata	41.15	7.00e-45	176.00
IUUC-Ola-087518	Oryzias latipes	76.70	0.00e+00	1054.00
IUUC-Oga-088743	Otolemur garnettii	87.27	0.00e+00	4006.00
IUUC-Oar-090265	Ovis aries	89.92	0.00e+00	4138.00
IUUC-Ptr-090521	Pan troglodytes	89.84	0.00e+00	4058.00
IUUC-Psi-093245	Pelodiscus sinensis	58.49	0.00e+00	1977.00
IUUC-Pfo-096066	Poecilia formosa	61.94	0.00e+00	1219.00
IUUC-Pab-098644	Pongo abelii	89.41	0.00e+00	4007.00
IUUC-Pva-103094	Pteropus vampyrus	87.00	0.00e+00	2095.00
IUUC-Rno-105803	Rattus norvegicus	81.92	0.00e+00	3672.00
IUUC-Sha-107278	Sarcophilus harrisii	69.24	0.00e+00	2999.00
IUUC-Sar-113402	Sorex araneus	78.33	0.00e+00	2597.00
IUUC-Sbi-114400	Sorghum bicolor	37.50	2.00e-13	67.80
IUUC-Ssc-116193	Sus scrofa	89.45	0.00e+00	4025.00
IUUC-Tgu-116532	Taeniopygia guttata	89.70	0.00e+00	1247.00
IUUC-Tru-117988	Takifugu rubripes	77.86	0.00e+00	1199.00
IUUC-Tsy-118830	Tarsius syrichta	88.61	0.00e+00	3540.00
IUUC-Tca-121456	Theobroma cacao	30.33	2.00e-19	91.30

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence