iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mga-059755

UUCD1 version

UUC-MeG-00518

Ensembl Protein ID

ENSMGAP00000011856.2

UniProt Accession

G1NFQ3; G1NFQ3_MELGA

Protein Name

Uncharacterized protein

Gene Name

SOCS2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMGAG00000011348.2	ENSMGAT00000012738.2	ENSMGAP00000011856.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box	9.90e-13	47.5	156	199

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box

   S: 5    wllrseprSLqhLCRlaIrrclgsqrlkaidkLPLPksLkdYLlyedyq 53
           ++l ++ +SLqh CR++I++c+ +     i++LPLP +Lk+YL+++ yq
   Q: 156  KPLYTSAPSLQHRCRITINKCTNQ-----IWELPLPTRLKEYLKEYRYQ 199
           5678999***************99.....8***************9886 PP

Organism

Meleagris gallopavo

Protein Sequence
(Fasta)

FLWQIKLYDA CRTPACEQHK KWVSADPSGE EQAVKQTAGS KSICAFSPSL PGWYWGNMSV 60
AEAKERLQDA PEGTFLVRDS SHSEYLLTIS VKTSAGPTNL RIEYQDGKFR LDSITCVRSR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTTCTATGGC AAATAAAACT TTATGATGCC TGCAGGACTC CAGCTTGCGA GCAGCACAAG 60
AAGTGGGTTA GTGCAGATCC GTCGGGCGAG GAGCAGGCTG TTAAACAGAC AGCCGGCAGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000980--SH2
IPR028410--SOCS2
IPR001496--SOCS_box

PROSITE

PS50001--SH2
PS50225--SOCS

Pfam

PF00017--SH2
PF07525--SOCS_box

PRINTS

PR00401--SH2DOMAIN

SMART

SM00252--SH2
SM00253--SOCS
SM00969--SOCS_box

Gene Ontology

GO:0005737--C:cytoplasm
GO:0060396--P:growth hormone receptor signaling pathway
GO:0035556--P:intracellular signal transduction
GO:0046426--P:negative regulation of JAK-STAT cascade
GO:0001558--P:regulation of cell growth
GO:0032355--P:response to estradiol

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002075	Ailuropoda melanoleuca	78.29	5.00e-70	256.00
IUUC-Apl-003484	Anas platyrhynchos	96.75	4.00e-87	312.00
IUUC-Aca-004253	Anolis carolinensis	85.53	1.00e-76	278.00
IUUC-Ame-011267	Astyanax mexicanus	61.29	8.00e-53	199.00
IUUC-Bta-013183	Bos taurus	78.29	1.00e-70	258.00
IUUC-Cja-018862	Callithrix jacchus	79.61	2.00e-71	261.00
IUUC-Cfa-020226	Canis familiaris	79.47	2.00e-70	257.00
IUUC-Cpo-022414	Cavia porcellus	79.61	2.00e-71	260.00
IUUC-Csa-023758	Chlorocebus sabaeus	78.95	7.00e-71	259.00
IUUC-Cho-024471	Choloepus hoffmanni	72.08	2.00e-58	218.00
IUUC-Dre-028288	Danio rerio	63.87	6.00e-56	209.00
IUUC-Dno-029565	Dasypus novemcinctus	79.08	7.00e-72	263.00
IUUC-Dor-030447	Dipodomys ordii	78.81	4.00e-70	255.00
IUUC-Ete-033023	Echinops telfairi	73.30	8.00e-73	265.00
IUUC-Fca-036469	Felis catus	78.95	9.00e-71	258.00
IUUC-Fal-036642	Ficedula albicollis	97.32	3.00e-85	306.00
IUUC-Gmo-039331	Gadus morhua	65.00	1.00e-29	120.00
IUUC-Gga-040809	Gallus gallus	100.00	2.00e-87	313.00
IUUC-Gac-041398	Gasterosteus aculeatus	51.30	4.00e-53	200.00
IUUC-Ggo-045341	Gorilla gorilla	79.61	2.00e-71	260.00
IUUC-Hsa-046557	Homo sapiens	79.61	1.00e-71	261.00
IUUC-Itr-049013	Ictidomys tridecemlineatus	79.08	1.00e-71	261.00
IUUC-Lch-050160	Latimeria chalumnae	55.03	2.00e-47	181.00
IUUC-Loc-051825	Lepisosteus oculatus	62.75	3.00e-56	210.00
IUUC-Laf-053560	Loxodonta africana	78.95	8.00e-71	258.00
IUUC-Mcc-055890	Macaca mulatta	78.29	3.00e-70	256.00
IUUC-Meu-056218	Macropus eugenii	69.19	5.00e-73	266.00
IUUC-Mmr-061387	Microcebus murinus	78.95	7.00e-71	259.00
IUUC-Mdo-062383	Monodelphis domestica	72.22	7.00e-74	269.00
IUUC-Mmu-063443	Mus musculus	77.63	1.00e-69	254.00
IUUC-Mpu-066459	Mustela putorius furo	76.97	6.00e-69	252.00
IUUC-Mlu-068040	Myotis lucifugus	78.95	6.00e-71	259.00
IUUC-Nle-069016	Nomascus leucogenys	79.74	5.00e-72	263.00
IUUC-Opr-071087	Ochotona princeps	65.61	2.00e-68	251.00
IUUC-Ont-072340	Oreochromis niloticus	58.49	1.00e-52	198.00
IUUC-Oan-073443	Ornithorhynchus anatinus	82.89	1.00e-74	271.00
IUUC-Ocu-074539	Oryctolagus cuniculus	77.48	1.00e-68	251.00
IUUC-Ola-087004	Oryzias latipes	56.96	2.00e-51	193.00
IUUC-Oga-088438	Otolemur garnettii	78.29	2.00e-70	257.00
IUUC-Oar-089932	Ovis aries	79.61	2.00e-71	261.00
IUUC-Ptr-091037	Pan troglodytes	79.61	2.00e-71	260.00
IUUC-Pan-092767	Papio anubis	78.95	7.00e-71	259.00
IUUC-Psi-093099	Pelodiscus sinensis	89.47	6.00e-78	281.00
IUUC-Pma-094671	Petromyzon marinus	43.33	2.00e-34	138.00
IUUC-Pfo-097073	Poecilia formosa	53.25	5.00e-48	183.00
IUUC-Pab-098319	Pongo abelii	79.61	2.00e-71	261.00
IUUC-Pca-101117	Procavia capensis	78.95	4.00e-70	256.00
IUUC-Pva-102117	Pteropus vampyrus	78.29	6.00e-70	256.00
IUUC-Rno-105913	Rattus norvegicus	76.97	8.00e-69	252.00
IUUC-Sha-106500	Sarcophilus harrisii	79.87	2.00e-72	264.00
IUUC-Ssc-115252	Sus scrofa	78.95	9.00e-71	258.00
IUUC-Tgu-117524	Taeniopygia guttata	95.97	1.00e-83	301.00
IUUC-Tsy-119335	Tarsius syrichta	77.48	7.00e-69	251.00
IUUC-Tni-120263	Tetraodon nigroviridis	56.60	8.00e-51	192.00
IUUC-Tbe-127915	Tupaia belangeri	78.95	2.00e-70	258.00
IUUC-Ttr-128372	Tursiops truncatus	78.95	1.00e-70	258.00
IUUC-Vpa-130422	Vicugna pacos	78.81	5.00e-70	255.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence