iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mpu-066459

Ensembl Protein ID

ENSMPUP00000007387.1

UniProt Accession

M3Y7T0; M3Y7T0_MUSPF

Genbank Protein ID

ENSMPUP00000007387

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEYP01024700

Gene Name

SOCS2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMPUG00000007443.1	ENSMPUT00000007507.1	ENSMPUP00000007387.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box	1.70e-16	59.8	152	197

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box

   S: 3    klwllrseprSLqhLCRlaIrrclgsqrlkaidkLPLPksLkdYLlyedyq 53
            +++l + +r+LqhLCRl+I++c+g+     i++LPLP +LkdYL+++++q
   Q: 152  LTKPLYTAVRPLQHLCRLTINKCTGT-----IWGLPLPTRLKDYLEEYKFQ 197
           5678999*******************.....8***************9886 PP

Organism

Mustela putorius furo

Protein Sequence
(Fasta)

MTLRCLEPSG NGAEGTQSQW GTAGSAEEPS PEAARLAKAL RELSQTGWYW GSMTVNEAKE 60
KLKEAPEGTF LIRDSSHSDY LLTISVKTSA GPTNLRIEYQ DGKFRLDSII CVKSKLKQFD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGACCCTGC GGTGCCTCGA GCCCTCCGGG AATGGCGCGG AAGGGACGCA GAGCCAGTGG 60
GGGACCGCGG GATCCGCGGA GGAGCCGTCC CCCGAAGCAG CGCGTTTGGC GAAGGCCCTA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000980--SH2
IPR028410--SOCS2
IPR001496--SOCS_box

PROSITE

PS50001--SH2
PS50225--SOCS

Pfam

PF00017--SH2
PF07525--SOCS_box

PRINTS

PR00401--SH2DOMAIN

SMART

SM00252--SH2
SM00253--SOCS
SM00969--SOCS_box

Gene Ontology

GO:0005737--C:cytoplasm
GO:0060396--P:growth hormone receptor signaling pathway
GO:0035556--P:intracellular signal transduction
GO:0046426--P:negative regulation of JAK-STAT cascade
GO:0016567--P:protein ubiquitination
GO:0001558--P:regulation of cell growth
GO:0032355--P:response to estradiol

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002075	Ailuropoda melanoleuca	97.47	2.00e-106	377.00
IUUC-Apl-003484	Anas platyrhynchos	77.78	3.00e-70	256.00
IUUC-Aca-004253	Anolis carolinensis	70.12	2.00e-69	254.00
IUUC-Ath-007106	Arabidopsis thaliana	35.59	2.50e-02	33.10
IUUC-Ame-011267	Astyanax mexicanus	62.28	1.00e-58	218.00
IUUC-Bta-013183	Bos taurus	95.96	6.00e-100	355.00
IUUC-Bra-017915	Brassica rapa	33.90	4.80e-02	32.00
IUUC-Cja-018862	Callithrix jacchus	95.45	2.00e-99	354.00
IUUC-Cfa-020226	Canis familiaris	95.43	4.00e-97	347.00
IUUC-Cpo-022414	Cavia porcellus	94.95	3.00e-103	367.00
IUUC-Csa-023758	Chlorocebus sabaeus	94.95	1.00e-103	368.00
IUUC-Cho-024471	Choloepus hoffmanni	84.62	5.00e-71	259.00
IUUC-Dre-028288	Danio rerio	56.48	2.00e-62	231.00
IUUC-Dno-029036	Dasypus novemcinctus	96.97	6.00e-106	375.00
IUUC-Dor-030447	Dipodomys ordii	96.69	2.00e-85	307.00
IUUC-Ete-033023	Echinops telfairi	92.42	2.00e-108	384.00
IUUC-Fca-036469	Felis catus	97.47	3.00e-101	360.00
IUUC-Fal-036642	Ficedula albicollis	71.60	2.00e-68	251.00
IUUC-Gmo-039331	Gadus morhua	61.54	2.00e-35	140.00
IUUC-Gga-040809	Gallus gallus	74.84	1.00e-70	258.00
IUUC-Gac-041398	Gasterosteus aculeatus	60.12	1.00e-58	219.00
IUUC-Ggo-045341	Gorilla gorilla	95.96	1.00e-99	354.00
IUUC-Hsa-046557	Homo sapiens	95.45	5.00e-112	396.00
IUUC-Itr-049013	Ictidomys tridecemlineatus	80.77	4.00e-91	327.00
IUUC-Lch-050160	Latimeria chalumnae	61.07	1.00e-48	185.00
IUUC-Loc-051825	Lepisosteus oculatus	55.21	3.00e-60	224.00
IUUC-Laf-053560	Loxodonta africana	94.44	6.00e-97	346.00
IUUC-Mcc-055890	Macaca mulatta	94.95	2.00e-98	351.00
IUUC-Meu-056218	Macropus eugenii	80.81	2.00e-95	340.00
IUUC-Mga-059755	Meleagris gallopavo	67.76	3.00e-69	254.00
IUUC-Mmr-061387	Microcebus murinus	96.46	1.00e-104	371.00
IUUC-Mdo-062383	Monodelphis domestica	81.31	5.00e-95	339.00
IUUC-Mmu-063443	Mus musculus	93.43	1.00e-100	358.00
IUUC-Mlu-068040	Myotis lucifugus	96.46	3.00e-106	377.00
IUUC-Nle-069016	Nomascus leucogenys	90.91	5.00e-97	346.00
IUUC-Opr-071087	Ochotona princeps	88.89	6.00e-103	366.00
IUUC-Ont-072340	Oreochromis niloticus	55.21	9.00e-58	216.00
IUUC-Oan-073443	Ornithorhynchus anatinus	77.78	4.00e-89	320.00
IUUC-Ocu-074539	Oryctolagus cuniculus	95.43	1.00e-99	355.00
IUUC-Ola-087004	Oryzias latipes	59.49	4.00e-54	203.00
IUUC-Oga-088438	Otolemur garnettii	94.95	2.00e-103	367.00
IUUC-Oar-089932	Ovis aries	95.96	1.00e-99	355.00
IUUC-Ptr-091037	Pan troglodytes	95.96	1.00e-99	354.00
IUUC-Pan-092767	Papio anubis	95.96	1.00e-99	355.00
IUUC-Psi-093099	Pelodiscus sinensis	75.47	4.00e-72	263.00
IUUC-Pma-094671	Petromyzon marinus	45.51	1.00e-34	139.00
IUUC-Pfo-097073	Poecilia formosa	50.52	5.00e-55	207.00
IUUC-Pab-098319	Pongo abelii	95.45	8.00e-105	372.00
IUUC-Pca-101117	Procavia capensis	93.43	4.00e-99	353.00
IUUC-Pva-102117	Pteropus vampyrus	95.45	7.00e-98	349.00
IUUC-Rno-105913	Rattus norvegicus	92.93	3.00e-100	357.00
IUUC-Sha-106500	Sarcophilus harrisii	81.22	1.00e-93	334.00
IUUC-Ssc-115252	Sus scrofa	97.47	2.00e-106	377.00
IUUC-Tgu-117524	Taeniopygia guttata	73.58	1.00e-67	248.00
IUUC-Tsy-119335	Tarsius syrichta	92.05	2.00e-82	297.00
IUUC-Tni-120263	Tetraodon nigroviridis	54.26	2.00e-55	208.00
IUUC-Tbe-127915	Tupaia belangeri	95.45	7.00e-97	345.00
IUUC-Ttr-128372	Tursiops truncatus	96.97	6.00e-106	375.00
IUUC-Vpa-130422	Vicugna pacos	98.01	7.00e-87	311.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence