iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Dre-027870

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Ubiquitin-specific peptidase 39

Genbank Nucleotide ID

BX537304

Gene Name

usp39

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSDARG00000041908.5	ENSDART00000061406.5	ENSDARP00000061405.5

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	5.00e-47	161.6	156	485

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelw..kskkkavsprellkalkkeaee.fsg 86
           +Gl+N+ +  Y N vLQ+Lsn+p+lr+++le+++ +  ++ p +    l++ + +l+++lw   + k +vsp+e+l+a+  ++++ f+ 
   Q: 156  VGLNNIKANDYANVVLQALSNVPPLRNYFLEEENYRGIRRPPGDIMFLLVQRFGELMRKLWnpRNFKAHVSPHEMLQAVVLCSKKtFQI 244
           6******************************99999999999*******************999999**************99999*** PP
   S: 87   yeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlk................sqikclec 159
           ++q Da +fl+++l++l+ +l                           +kk++s+i++ Fqg+++                + +  +e 
   Q: 245  TKQGDAVDFLSWFLNALHGAL-------------------------GGTKKKSSIITKAFQGSMRifskklphpdlppeekEALLLKEE 308
           *********************.........................4678888899999999999999999999999988799999999 PP
   S: 160  dnvssreepfldlslpvpgkeetkke.........slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsf 239
            ++  +e++fl+l+l++p     k e          l ++L +f  + e e    y++ k     +  k+++l+klP++Li+ +kRf  
   Q: 309  YQEEMSESTFLYLTLDLPTAPLYKDEkeqliipqvPLFNILGKFNGNTEKE----YKTYK----ENFLKRFQLTKLPPYLIFCIKRF-- 387
           9999**************777666664555666667777777777766666....44443....44899******************.. PP
   S: 240  seeqksrekinkkvefple.LdlspfctspeekqkekkkYeLiavvvHsGslssGHYvayvkn.ekgkWllfdDskVtevkeeevleet 326
           ++++ + ek+ + v+fp++ +dl++++t++ +  +++++Y+L+a vvH G++ +G Y  +v +  +gkW+++ D +V  +  + +    
   Q: 388  TKNNFFVEKNPTIVNFPITnVDLREYLTEEAQVTEKNTTYDLVANVVHDGKPTEGSYRIHVLHhGTGKWYELQDLQVIDILPQMITL-- 474
           88889**************************99999*************************9935666******************9.. PP
   S: 327  gstaYvlfYkrr 338
            s+aY+ ++kr+
   Q: 475  -SEAYIQIWKRQ 485
           .********986 PP

Organism

Danio rerio

Protein Sequence
(Fasta)

MIRGVKRERD FDEDEEKEVR VKVGRGYVED RRSRHCPYLD TINRSVLDFD FEKLCSISLS 60
HINVYACLIC GKYFQGRGQK SHAYIHSVQV AHHVFLNLHT LKFYCLPDNY EIIDSSLEDI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGGAAGTGCA AGCGGGAGTT TTGTAACGCG TTCACAGTGC GTTCATTCAG CGCTGAATTT 60
ACTTGATTTA TAGTTGTTAT TTACCTTAAA ATATGATCAG AGGCGTGAAA CGGGAGAGGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001394--Peptidase_C19_UCH
IPR033809--USP39
IPR028889--USP_dom
IPR013083--Znf_RING/FYVE/PHD
IPR001607--Znf_UBP

PROSITE

PS50235--USP_3
PS50271--ZF_UBP

Pfam

PF00443--UCH
PF02148--zf-UBP

SMART

SM00290--ZnF_UBP

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0008270--F:zinc ion binding
GO:0048855--P:adenohypophysis morphogenesis
GO:0016579--P:protein deubiquitination
GO:0043484--P:regulation of RNA splicing
GO:0000245--P:spliceosomal complex assembly

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000483	Aegilops tauschii	52.49	1.00e-126	446.00
IUUC-Aml-001846	Ailuropoda melanoleuca	87.45	0.00e+00	887.00
IUUC-Atr-002758	Amborella trichopoda	51.81	7.00e-131	461.00
IUUC-Apl-003336	Anas platyrhynchos	81.44	5.00e-156	543.00
IUUC-Aca-004846	Anolis carolinensis	89.29	0.00e+00	832.00
IUUC-Aly-005683	Arabidopsis lyrata	51.58	2.00e-123	436.00
IUUC-Ath-007661	Arabidopsis thaliana	50.32	5.00e-122	431.00
IUUC-Ago-007802	Ashbya gossypii	29.61	5.00e-59	222.00
IUUC-Acl-008304	Aspergillus clavatus	43.33	9.00e-96	344.00
IUUC-Afl-008735	Aspergillus flavus	60.50	3.00e-41	163.00
IUUC-Afu-009100	Aspergillus fumigatus	47.36	1.00e-94	340.00
IUUC-Ani-009138	Aspergillus nidulans	50.12	6.00e-98	351.00
IUUC-Ang-009661	Aspergillus niger	44.09	1.00e-99	357.00
IUUC-Aor-010235	Aspergillus oryzae	39.92	8.00e-84	304.00
IUUC-Ate-010346	Aspergillus terreus	38.61	5.00e-76	278.00
IUUC-Ame-011688	Astyanax mexicanus	95.35	0.00e+00	908.00
IUUC-Bgr-011998	Blumeria graminis	48.03	1.00e-116	413.00
IUUC-Bta-013407	Bos taurus	87.27	0.00e+00	876.00
IUUC-Bci-013977	Botrytis cinerea	48.70	1.00e-115	410.00
IUUC-Bdi-014361	Brachypodium distachyon	51.84	3.00e-131	462.00
IUUC-Bol-016317	Brassica oleracea	50.98	1.00e-120	427.00
IUUC-Bra-017952	Brassica rapa	50.83	4.00e-122	431.00
IUUC-Cel-018491	Caenorhabditis elegans	62.61	0.00e+00	628.00
IUUC-Cja-019134	Callithrix jacchus	87.25	0.00e+00	886.00
IUUC-Cfa-020098	Canis familiaris	87.25	0.00e+00	885.00
IUUC-Cpo-021595	Cavia porcellus	87.94	0.00e+00	877.00
IUUC-Cre-022886	Chlamydomonas reinhardtii	50.81	1.00e-30	124.00
IUUC-Csa-024121	Chlorocebus sabaeus	87.25	0.00e+00	886.00
IUUC-Cho-025057	Choloepus hoffmanni	71.43	2.00e-80	292.00
IUUC-Cin-025473	Ciona intestinalis	62.84	4.00e-63	234.00
IUUC-Csv-025815	Ciona savignyi	80.17	3.00e-119	422.00
IUUC-Cgl-026416	Colletotrichum gloeosporioides	44.14	1.00e-109	390.00
IUUC-Cne-026802	Cryptococcus neoformans	43.50	2.00e-102	366.00
IUUC-Dno-029655	Dasypus novemcinctus	87.06	0.00e+00	877.00
IUUC-Dor-030762	Dipodomys ordii	87.27	0.00e+00	876.00
IUUC-Dse-031441	Dothistroma septosporum	44.82	1.00e-109	390.00
IUUC-Dme-032101	Drosophila melanogaster	65.22	2.00e-180	625.00
IUUC-Ete-032841	Echinops telfairi	83.40	0.00e+00	843.00
IUUC-Eca-033463	Equus caballus	87.25	0.00e+00	883.00
IUUC-Eeu-034438	Erinaceus europaeus	75.17	4.00e-126	445.00
IUUC-Fca-035774	Felis catus	87.25	0.00e+00	885.00
IUUC-Fal-036988	Ficedula albicollis	87.39	0.00e+00	869.00
IUUC-Fox-037895	Fusarium oxysporum	46.15	4.00e-108	385.00
IUUC-Fso-038450	Fusarium solani	46.79	3.00e-109	389.00
IUUC-Gmo-038874	Gadus morhua	92.87	0.00e+00	867.00
IUUC-Ggr-040115	Gaeumannomyces graminis	44.40	6.00e-104	371.00
IUUC-Gac-041650	Gasterosteus aculeatus	91.65	0.00e+00	909.00
IUUC-Gma-043697	Glycine max	52.46	3.00e-132	465.00
IUUC-Ggo-044707	Gorilla gorilla	81.38	0.00e+00	809.00
IUUC-Hsa-046041	Homo sapiens	87.25	0.00e+00	885.00
IUUC-Hvu-047816	Hordeum vulgare	51.08	1.00e-120	426.00
IUUC-Itr-048945	Ictidomys tridecemlineatus	87.61	2.00e-176	611.00
IUUC-Lch-050419	Latimeria chalumnae	89.72	0.00e+00	882.00
IUUC-Lpe-051593	Leersia perrieri	53.59	1.00e-133	470.00
IUUC-Loc-052930	Lepisosteus oculatus	90.14	0.00e+00	897.00
IUUC-Lma-053256	Leptosphaeria maculans	47.53	5.00e-114	404.00
IUUC-Laf-053555	Loxodonta africana	87.04	0.00e+00	878.00
IUUC-Mcc-055630	Macaca mulatta	87.25	0.00e+00	886.00
IUUC-Meu-056579	Macropus eugenii	85.19	9.00e-160	556.00
IUUC-Mor-057078	Magnaporthe oryzae	45.40	2.00e-106	379.00
IUUC-Mpo-057607	Magnaporthe poae	38.78	1.00e-84	307.00
IUUC-Mtr-058644	Medicago truncatula	52.47	4.00e-131	461.00
IUUC-Mla-059120	Melampsora laricipopulina	43.13	1.00e-100	360.00
IUUC-Mvi-060429	Microbotryum violaceum	47.67	3.00e-71	262.00
IUUC-Mmr-061313	Microcebus murinus	87.22	0.00e+00	884.00
IUUC-Mdo-062801	Monodelphis domestica	87.45	0.00e+00	887.00
IUUC-Mmu-064424	Mus musculus	87.17	0.00e+00	895.00
IUUC-Mac-064694	Musa acuminata	51.12	1.00e-129	457.00
IUUC-Mpu-065980	Mustela putorius furo	88.60	0.00e+00	761.00
IUUC-Mlu-067007	Myotis lucifugus	87.45	0.00e+00	878.00
IUUC-Nfi-068274	Neosartorya fischeri	48.90	1.00e-94	340.00
IUUC-Ncr-068829	Neurospora crassa	47.84	8.00e-108	384.00
IUUC-Nle-069171	Nomascus leucogenys	88.03	0.00e+00	863.00
IUUC-Opr-070494	Ochotona princeps	80.29	0.00e+00	781.00
IUUC-Ont-072290	Oreochromis niloticus	90.56	0.00e+00	936.00
IUUC-Oan-073099	Ornithorhynchus anatinus	88.28	0.00e+00	866.00
IUUC-Ocu-074642	Oryctolagus cuniculus	87.25	0.00e+00	886.00
IUUC-Oba-075886	Oryza barthii	53.59	2.00e-133	469.00
IUUC-Obr-076220	Oryza brachyantha	53.16	2.00e-133	469.00
IUUC-Ogl-077682	Oryza glaberrima	53.59	1.00e-133	470.00
IUUC-Ogu-078492	Oryza glumaepatula	53.38	4.00e-133	468.00
IUUC-Oin-079956	Oryza indica	53.38	2.00e-133	469.00
IUUC-Olo-080239	Oryza longistaminata	47.10	3.00e-106	380.00
IUUC-Ome-081573	Oryza meridionalis	53.59	1.00e-133	470.00
IUUC-Oni-082975	Oryza nivara	53.38	2.00e-133	469.00
IUUC-Opu-083724	Oryza punctata	53.59	1.00e-133	470.00
IUUC-Oru-084566	Oryza rufipogon	53.59	1.00e-133	469.00
IUUC-Osa-086008	Oryza sativa	53.59	2.00e-133	469.00
IUUC-Ola-086967	Oryzias latipes	94.69	0.00e+00	905.00
IUUC-Olu-087614	Ostreococcus lucimarinus	43.70	2.00e-99	356.00
IUUC-Oga-088047	Otolemur garnettii	73.77	5.00e-168	583.00
IUUC-Oar-089393	Ovis aries	87.25	0.00e+00	885.00
IUUC-Ptr-090561	Pan troglodytes	87.25	0.00e+00	885.00
IUUC-Pan-091812	Papio anubis	87.25	0.00e+00	887.00
IUUC-Psi-093507	Pelodiscus sinensis	87.58	2.00e-150	525.00
IUUC-Pno-095104	Phaeosphaeria nodorum	46.51	1.00e-112	400.00
IUUC-Ppa-095995	Physcomitrella patens	53.20	3.00e-137	482.00
IUUC-Pfo-096754	Poecilia formosa	93.18	0.00e+00	921.00
IUUC-Pab-098053	Pongo abelii	87.25	0.00e+00	885.00
IUUC-Pop-099230	Populus trichocarpa	51.56	6.00e-136	478.00
IUUC-Pca-100407	Procavia capensis	79.96	0.00e+00	788.00
IUUC-Ppe-101699	Prunus persica	50.86	5.00e-131	461.00
IUUC-Pva-103159	Pteropus vampyrus	84.62	0.00e+00	837.00
IUUC-Pgr-103433	Puccinia graminis	43.24	2.00e-105	377.00
IUUC-Ptt-103701	Puccinia triticina	40.49	9.00e-94	337.00
IUUC-Pte-104281	Pyrenophora teres	47.61	7.00e-113	400.00
IUUC-Pyt-104714	Pyrenophora triticirepentis	47.61	1.00e-112	400.00
IUUC-Rno-105531	Rattus norvegicus	87.65	0.00e+00	900.00
IUUC-Sce-106368	Saccharomyces cerevisiae	30.04	4.00e-47	182.00
IUUC-Sha-107093	Sarcophilus harrisii	87.65	0.00e+00	883.00
IUUC-Sja-108004	Schizosaccharomyces japonicus	45.04	2.00e-117	416.00
IUUC-Spo-108018	Schizosaccharomyces pombe	46.83	4.00e-114	405.00
IUUC-Ssl-108460	Sclerotinia sclerotiorum	45.94	5.00e-107	381.00
IUUC-Smo-108892	Selaginella moellendorffii	54.07	3.00e-136	478.00
IUUC-Sit-110782	Setaria italica	53.33	1.00e-134	473.00
IUUC-Sly-111308	Solanum lycopersicum	51.98	2.00e-140	492.00
IUUC-Stu-112447	Solanum tuberosum	53.59	1.00e-140	493.00
IUUC-Sar-113352	Sorex araneus	81.43	0.00e+00	691.00
IUUC-Sbi-114806	Sorghum bicolor	53.88	8.00e-134	470.00
IUUC-Sre-115059	Sporisorium reilianum	49.82	2.00e-74	273.00
IUUC-Ssc-115677	Sus scrofa	86.27	0.00e+00	628.00
IUUC-Tru-118478	Takifugu rubripes	91.02	0.00e+00	916.00
IUUC-Tsy-119082	Tarsius syrichta	76.67	0.00e+00	647.00
IUUC-Tni-120419	Tetraodon nigroviridis	91.74	0.00e+00	895.00
IUUC-Tca-121294	Theobroma cacao	52.58	6.00e-140	491.00
IUUC-Tre-121962	Trichoderma reesei	46.88	1.00e-104	374.00
IUUC-Tvi-122280	Trichoderma virens	46.55	4.00e-112	398.00
IUUC-Tae-125873	Triticum aestivum	53.56	6.00e-133	468.00
IUUC-Tur-126551	Triticum urartu	53.56	1.00e-132	466.00
IUUC-Tme-126959	Tuber melanosporum	47.21	5.00e-116	411.00
IUUC-Tbe-127737	Tupaia belangeri	83.37	0.00e+00	828.00
IUUC-Ttr-129211	Tursiops truncatus	89.47	2.00e-143	503.00
IUUC-Uma-129591	Ustilago maydis	39.92	1.00e-97	350.00
IUUC-Vda-129674	Verticillium dahliae	44.16	1.00e-96	347.00
IUUC-Vpa-130793	Vicugna pacos	77.82	0.00e+00	761.00
IUUC-Xtr-132430	Xenopus tropicalis	86.10	0.00e+00	851.00
IUUC-Xma-133515	Xiphophorus maculatus	93.30	0.00e+00	913.00
IUUC-Yli-134488	Yarrowia lipolytica	38.38	1.00e-76	280.00
IUUC-Zma-134748	Zea mays	53.65	2.00e-134	472.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence