iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Xma-133176

Ensembl Protein ID

ENSXMAP00000011813.1

UniProt Accession

M4ABG9; M4ABG9_XIPMA

Genbank Protein ID

ENSXMAP00000011813

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGAJ01045394

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSXMAG00000011719.1	ENSXMAT00000011829.1	ENSXMAP00000011813.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	7.40e-115	383.8	249	902
ULD/UDP/UBQ/UBQ_Other	6.50e-11	42.0	96	166

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgye 88
           +Gl+NlgNtC+mNS+LQcLsn+++l+e++l+ +++ ++n+enp ++ ge+++++++l++++w s++++v+pr+++++++++a++fsgy+
   Q: 249  CGLSNLGNTCFMNSALQCLSNVSPLTEYFLTdQYEAEINRENPLGMRGEIAEAYADLVKQMWMSRSSYVAPRTFKTQVGRFAPQFSGYQ 337
           7*****************************999******************************************************** PP
   S: 89   qqDaqEflaflldqleeelkkeknkpkeeeeeedkselsde.....aeekkkkknkslisdlFqgqlksqikclecdnvssreepfldl 172
           qqD+qE+laflld+l+e+l++ k+kp+  +++++   ++d+     a+ ++  +n+s+i+d+F+g +ks+++c+ec +vs++++pf++l
   Q: 338  QQDSQELLAFLLDGLHEDLNRVKKKPYLALRDAE--GRPDDivakeAWTNHRLRNDSVIVDIFHGLFKSTLVCPECSKVSVTFDPFCYL 424
           ****************************998888..6666667888******************************************* PP
   S: 173  slpvpgkeetkke............................................................................ 185
           +lp+p+k+++ +e                                                                            
   Q: 425  TLPLPMKKDRTMEvflvqsdpqskptqfrvvvpklgavtdlcsalsrlcgipsekmvvadvynhrfhkiyrrddalnqimekddifvye 513
           ********99999**************************************************************************** PP
   S: 186  ......................................................................................... 185
                                                                                                    
   Q: 514  vqeedsermnlpvyfrerhskhvgsssstllfgqpllisvprhnlladvlydkilerigryvkqqhspnsesrasasatlssssqtpec 602
           ***************************************************************************************** PP
   S: 186  ......................................................................................... 185
                                                                                                    
   Q: 603  stsstlnaslggcgspqsdgascsasssngsnhsgtcneanglydgeeeamdhqvspepengpseeeeessdlengskgnaaklftfsi 691
           ***************************************************************************************** PP
   S: 186  ................................................................slqdcLesftkeeelegenkyycek 210
                                                                            l++c+e ft+ e+l +++ +yc++
   Q: 692  vnsygtvnisplpcdgnvlklnphstvaidwdteskkqfydeqeaevyekhdsmlqpqkkkttvALKECIELFTTMETLGEHDPWYCPT 780
           ***************************************************************************************** PP
   S: 211  ckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefple.LdlspfctspeekqkekkkYeLiavvvHsGslssGHYvay 298
           ckk+q+a+kk++l++lP++L++hLkRfs+++  + r k+++ v+fp++ L++s+f+++p+ +   ++ Y+Liav +H+G++++GHY+ay
   Q: 781  CKKHQQATKKFDLWSLPRILVVHLKRFSYNR--CWRDKLDTLVDFPIRdLNMSEFVCDPKAG---PYVYDLIAVSNHYGGMGGGHYTAY 864
           ***************************9966..6778*********************9987...8*********************** PP
   S: 299  vkne.kgkWllfdDskVtevkeeevleetgstaYvlfYkrr 338
            kn+ +gkW++fdDs+V++ +e+++++   + aYvlfY+rr
   Q: 865  GKNKmDGKWYYFDDSSVSSASEDQIVT---KAAYVLFYQRR 902
           ***62566*******************...*********96 PP

ULD/UDP/UBQ/UBQ_Other

   S: 12   eltlkvnpsdtVaeLKekiekklgip.peqqrLiyk.....GkiL.eddktLadyglkdgstihllekksg 75
           + t++++++dt+ ++ ++++++++ip + + rL++k      + L ++d t++d gl++g+++++++k+++
   Q: 96   VITRHFSKADTIDTIEKEMRTLFNIPsEKETRLWNKymsntYEQLnKPDSTVQDAGLFQGQVLVIERKNED 166
           77899*********************777*****999987744457*******************999876 PP

Organism

Xiphophorus maculatus

Protein Sequence
(Fasta)

MYNVGERSLY PGPIDNSGLF SDQETQALKE HLIDELDYVL VPTEAWNKLV SWYSCLEGQR 60
PIVRKVVEHG MFVKHCKVEV YLLELSLCEN DNMENVITRH FSKADTIDTI EKEMRTLFNI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AAAACTGACT CTTTTCTGAC TGGCTCTGTG GTAACTTCTG ACTTTTAATC AATTTTGTCT 60
GTCTTAGGTA TCTTATAGAC AGTCGATGGT TCAAACAGTG GAAAAAGTAT GTGGGATATG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR006615--Pept_C19_DUSP
IPR001394--Peptidase_C19_UCH
IPR028135--Ub_USP-typ
IPR029346--USP_C
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS51283--DUSP
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF06337--DUSP
PF14836--Ubiquitin_3
PF00443--UCH
PF14533--USP7_C2

SMART

SM00695--DUSP

Gene Ontology

GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0034122--P:negative regulation of toll-like receptor signaling pathway
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000058	Aegilops tauschii	55.23	3.00e-77	283.00
IUUC-Ago-007911	Ashbya gossypii	40.46	4.00e-63	237.00
IUUC-Acl-008284	Aspergillus clavatus	37.20	4.00e-55	210.00
IUUC-Afl-008507	Aspergillus flavus	39.36	1.00e-56	216.00
IUUC-Afu-008878	Aspergillus fumigatus	34.96	1.00e-58	222.00
IUUC-Ang-009562	Aspergillus niger	38.26	8.00e-57	216.00
IUUC-Aor-009949	Aspergillus oryzae	35.96	3.00e-56	214.00
IUUC-Ate-010323	Aspergillus terreus	38.73	3.00e-58	221.00
IUUC-Ame-011064	Astyanax mexicanus	77.73	0.00e+00	1068.00
IUUC-Bgr-012277	Blumeria graminis	45.52	2.00e-65	245.00
IUUC-Bta-012929	Bos taurus	65.93	0.00e+00	1182.00
IUUC-Bci-013993	Botrytis cinerea	45.70	3.00e-66	247.00
IUUC-Cfa-020599	Canis familiaris	66.70	0.00e+00	1168.00
IUUC-Cpo-022144	Cavia porcellus	64.10	0.00e+00	1158.00
IUUC-Cgl-026741	Colletotrichum gloeosporioides	37.11	9.00e-65	243.00
IUUC-Cme-027338	Cyanidioschyzon merolae	58.46	4.00e-67	249.00
IUUC-Dre-027869	Danio rerio	81.06	0.00e+00	1397.00
IUUC-Dno-029316	Dasypus novemcinctus	67.07	0.00e+00	1173.00
IUUC-Ete-032970	Echinops telfairi	62.02	0.00e+00	758.00
IUUC-Fal-037634	Ficedula albicollis	65.40	0.00e+00	1113.00
IUUC-Fso-038291	Fusarium solani	47.10	2.00e-67	251.00
IUUC-Gmo-038866	Gadus morhua	86.36	0.00e+00	918.00
IUUC-Ggr-039740	Gaeumannomyces graminis	45.05	2.00e-64	241.00
IUUC-Gac-042631	Gasterosteus aculeatus	91.95	0.00e+00	1061.00
IUUC-Loc-051800	Lepisosteus oculatus	75.60	0.00e+00	1442.00
IUUC-Mor-056985	Magnaporthe oryzae	42.39	8.00e-62	233.00
IUUC-Mpo-057486	Magnaporthe poae	45.79	2.00e-64	241.00
IUUC-Mpu-066920	Mustela putorius furo	67.03	0.00e+00	1170.00
IUUC-Nfi-068330	Neosartorya fischeri	29.64	1.00e-59	226.00
IUUC-Ont-072573	Oreochromis niloticus	91.61	0.00e+00	1600.00
IUUC-Oan-073363	Ornithorhynchus anatinus	61.17	0.00e+00	820.00
IUUC-Ola-086553	Oryzias latipes	86.50	0.00e+00	1522.00
IUUC-Oar-090439	Ovis aries	66.67	0.00e+00	1173.00
IUUC-Psi-093942	Pelodiscus sinensis	63.23	0.00e+00	1099.00
IUUC-Pfo-097060	Poecilia formosa	97.64	0.00e+00	1682.00
IUUC-Pca-100161	Procavia capensis	69.71	0.00e+00	787.00
IUUC-Ptt-103847	Puccinia triticina	37.44	2.00e-62	234.00
IUUC-Sly-111746	Solanum lycopersicum	40.52	2.00e-103	370.00
IUUC-Sar-113542	Sorex araneus	71.11	0.00e+00	830.00
IUUC-Ssc-115637	Sus scrofa	71.26	0.00e+00	824.00
IUUC-Tgu-117267	Taeniopygia guttata	62.59	0.00e+00	1086.00
IUUC-Tru-118634	Takifugu rubripes	88.91	0.00e+00	980.00
IUUC-Tni-120107	Tetraodon nigroviridis	80.99	0.00e+00	1059.00
IUUC-Tre-121888	Trichoderma reesei	42.32	2.00e-64	241.00
IUUC-Tvi-122422	Trichoderma virens	41.88	2.00e-59	225.00
IUUC-Uma-129498	Ustilago maydis	40.90	4.00e-71	263.00
IUUC-Vpa-130571	Vicugna pacos	71.94	0.00e+00	823.00
IUUC-Xtr-132305	Xenopus tropicalis	64.46	0.00e+00	1163.00
IUUC-Yli-134392	Yarrowia lipolytica	43.88	1.00e-63	238.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence