iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Aml-001963

Ensembl Protein ID

ENSAMEP00000012770.1

UniProt Accession

G1M0B0; G1M0B0_AILME

Genbank Protein ID

ENSAMEP00000012770

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ACTA01000737

Gene Name

KDM5B

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMEG00000012088.1	ENSAMET00000013310.1	ENSAMEP00000012770.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	4.20e-22	78.2	243	289

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 3    vClvCgeggedekslveCekCrewfHpaClklsveeelpnsekwiCpkCr 52
           vCl+Cg+g +++  l+ C+ C++ +H  Cl ++   ++p+ + w CpkC 
   Q: 243  VCLLCGSGNDED-RLLLCDGCDDSYHTFCLIPP-LHDVPKGD-WRCPKCL 289
           8********988.6*******************.*******7.******5 PP

Organism

Ailuropoda melanoleuca

Protein Sequence
(Fasta)

DWQPPFACDV DKLHFTPRIQ RLNELEAQTR VKLNFLDQIA KYWELQGSTL KIPHVERKIL 60
DLFQLNKLVA EEGGFAVVCK DRKWTKIATK MGFAPGKAVG SHIRGHYERI LNPYNLFLSG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GATTGGCAGC CACCATTTGC ATGTGATGTT GATAAACTTC ATTTTACCCC ACGTATCCAG 60
AGGCTGAATG AATTGGAGGT AATATCTTAG CTGTTGTTCT GGTGGACTGT ATTCCAGAGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001606--ARID_dom
IPR003347--JmjC_dom
IPR013637--Lys_sp_deMease-like_dom
IPR019786--Zinc_finger_PHD-type_CS
IPR004198--Znf_C5HC2
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51011--ARID
PS51184--JMJC
PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF01388--ARID
PF02373--JmjC
PF00628--PHD
PF08429--PLU-1
PF02928--zf-C5HC2

SMART

SM00501--BRIGHT
SM00558--JmjC
SM00249--PHD

Gene Ontology

GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0003677--F:DNA binding
GO:0034648--F:histone demethylase activity (H3-dimethyl-K4 specific)
GO:0034647--F:histone demethylase activity (H3-trimethyl-K4 specific)
GO:0016706--F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
GO:0003714--F:transcription corepressor activity
GO:0008270--F:zinc ion binding
GO:0060444--P:branching involved in mammary gland duct morphogenesis
GO:0060763--P:mammary duct terminal end bud growth
GO:0045892--P:negative regulation of transcription, DNA-templated
GO:0010628--P:positive regulation of gene expression
GO:0033601--P:positive regulation of mammary gland epithelial cell proliferation
GO:0009791--P:post-embryonic development
GO:2000864--P:regulation of estradiol secretion
GO:0007338--P:single fertilization
GO:0061038--P:uterus morphogenesis

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000552	Aegilops tauschii	32.99	5.00e-102	366.00
IUUC-Apl-003770	Anas platyrhynchos	86.21	0.00e+00	2170.00
IUUC-Aca-004867	Anolis carolinensis	80.99	0.00e+00	2397.00
IUUC-Ath-007218	Arabidopsis thaliana	35.16	2.00e-09	59.30
IUUC-Acl-008162	Aspergillus clavatus	31.41	8.00e-114	405.00
IUUC-Ame-010620	Astyanax mexicanus	62.03	0.00e+00	1846.00
IUUC-Bta-012733	Bos taurus	91.88	0.00e+00	2655.00
IUUC-Bol-015336	Brassica oleracea	36.11	2.00e-14	76.30
IUUC-Bra-017998	Brassica rapa	34.75	4.00e-13	72.00
IUUC-Cja-019050	Callithrix jacchus	96.07	0.00e+00	2808.00
IUUC-Cfa-021015	Canis familiaris	98.51	0.00e+00	2835.00
IUUC-Cpo-022340	Cavia porcellus	95.60	0.00e+00	2727.00
IUUC-Csa-023441	Chlorocebus sabaeus	96.68	0.00e+00	2778.00
IUUC-Cho-024823	Choloepus hoffmanni	98.24	0.00e+00	1627.00
IUUC-Cgl-026613	Colletotrichum gloeosporioides	29.93	5.00e-107	383.00
IUUC-Cne-026851	Cryptococcus neoformans	28.98	1.00e-110	395.00
IUUC-Dre-027707	Danio rerio	60.81	0.00e+00	1764.00
IUUC-Dno-028978	Dasypus novemcinctus	95.94	0.00e+00	2757.00
IUUC-Dor-030854	Dipodomys ordii	85.82	0.00e+00	1908.00
IUUC-Ete-032760	Echinops telfairi	90.60	0.00e+00	1847.00
IUUC-Eca-034370	Equus caballus	96.55	0.00e+00	2708.00
IUUC-Eeu-035012	Erinaceus europaeus	77.21	0.00e+00	1892.00
IUUC-Fca-035494	Felis catus	98.10	0.00e+00	2803.00
IUUC-Fal-037631	Ficedula albicollis	83.25	0.00e+00	2421.00
IUUC-Gmo-039522	Gadus morhua	58.01	0.00e+00	1643.00
IUUC-Gga-040802	Gallus gallus	83.29	0.00e+00	2356.00
IUUC-Gac-041563	Gasterosteus aculeatus	61.33	0.00e+00	1779.00
IUUC-Gma-042675	Glycine max	33.04	7.00e-102	366.00
IUUC-Ggo-044856	Gorilla gorilla	79.34	0.00e+00	2150.00
IUUC-Hsa-045888	Homo sapiens	94.51	0.00e+00	2789.00
IUUC-Hvu-047583	Hordeum vulgare	42.50	1.00e-15	79.00
IUUC-Itr-048297	Ictidomys tridecemlineatus	96.61	0.00e+00	2749.00
IUUC-Lch-050483	Latimeria chalumnae	66.05	0.00e+00	1971.00
IUUC-Lpe-051537	Leersia perrieri	31.51	4.00e-92	333.00
IUUC-Loc-052550	Lepisosteus oculatus	70.83	0.00e+00	2038.00
IUUC-Laf-053761	Loxodonta africana	94.58	0.00e+00	2717.00
IUUC-Mcc-055505	Macaca mulatta	94.51	0.00e+00	2786.00
IUUC-Mga-059358	Meleagris gallopavo	82.63	0.00e+00	2419.00
IUUC-Mmr-060863	Microcebus murinus	96.41	0.00e+00	2766.00
IUUC-Mdo-061957	Monodelphis domestica	89.03	0.00e+00	2623.00
IUUC-Mmu-063944	Mus musculus	93.43	0.00e+00	2674.00
IUUC-Mac-065069	Musa acuminata	36.61	1.00e-08	57.00
IUUC-Mpu-066719	Mustela putorius furo	96.74	0.00e+00	2819.00
IUUC-Mlu-068086	Myotis lucifugus	87.68	0.00e+00	2542.00
IUUC-Nle-069256	Nomascus leucogenys	94.65	0.00e+00	2790.00
IUUC-Ont-071756	Oreochromis niloticus	61.97	0.00e+00	1821.00
IUUC-Oan-073568	Ornithorhynchus anatinus	89.88	0.00e+00	2613.00
IUUC-Ocu-073961	Oryctolagus cuniculus	92.69	0.00e+00	2682.00
IUUC-Ogl-077886	Oryza glaberrima	39.42	5.00e-17	83.20
IUUC-Oin-079273	Oryza indica	40.54	6.00e-14	70.10
IUUC-Olo-080668	Oryza longistaminata	39.42	2.00e-16	82.80
IUUC-Opu-083164	Oryza punctata	31.95	2.00e-88	321.00
IUUC-Osa-085487	Oryza sativa	39.42	5.00e-17	83.20
IUUC-Ola-086448	Oryzias latipes	61.54	0.00e+00	1774.00
IUUC-Oga-088501	Otolemur garnettii	92.23	0.00e+00	2378.00
IUUC-Oar-090162	Ovis aries	91.06	0.00e+00	2643.00
IUUC-Ptr-090816	Pan troglodytes	94.58	0.00e+00	2793.00
IUUC-Pan-092764	Papio anubis	96.82	0.00e+00	2781.00
IUUC-Psi-093918	Pelodiscus sinensis	83.06	0.00e+00	2234.00
IUUC-Pfo-096672	Poecilia formosa	61.60	0.00e+00	1749.00
IUUC-Pab-097854	Pongo abelii	93.73	0.00e+00	2124.00
IUUC-Pca-100241	Procavia capensis	91.08	0.00e+00	1795.00
IUUC-Pva-103035	Pteropus vampyrus	85.36	0.00e+00	2215.00
IUUC-Rno-105574	Rattus norvegicus	91.89	0.00e+00	2610.00
IUUC-Sce-106207	Saccharomyces cerevisiae	35.51	3.00e-74	273.00
IUUC-Sly-111298	Solanum lycopersicum	42.34	6.00e-103	369.00
IUUC-Sar-113477	Sorex araneus	91.52	0.00e+00	2442.00
IUUC-Ssc-116132	Sus scrofa	95.15	0.00e+00	2373.00
IUUC-Tgu-117452	Taeniopygia guttata	83.57	0.00e+00	2418.00
IUUC-Tru-117561	Takifugu rubripes	62.91	0.00e+00	1649.00
IUUC-Tsy-119271	Tarsius syrichta	94.43	0.00e+00	2175.00
IUUC-Tni-119650	Tetraodon nigroviridis	60.91	0.00e+00	1747.00
IUUC-Tur-126632	Triticum urartu	33.12	2.00e-101	364.00
IUUC-Tbe-127890	Tupaia belangeri	90.09	0.00e+00	1549.00
IUUC-Ttr-128546	Tursiops truncatus	90.96	0.00e+00	1949.00
IUUC-Vpa-130432	Vicugna pacos	90.24	0.00e+00	1582.00
IUUC-Xtr-132008	Xenopus tropicalis	70.90	0.00e+00	2078.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence