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Tag Content
UUCD2 ID IUUC-Cfa-021088
UUCD1 version UUC-CaF-00501
Ensembl Protein ID ENSCAFP00000021058.3
UniProt Accession E2RRJ5; E2RRJ5_CANLF
Genbank Protein ID ENSCAFP00000021058
Protein Name Uncharacterized protein
Genbank Nucleotide ID AAEX03005193
Gene Name RFWD2
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSCAFG00000014263.3 ENSCAFT00000022674.3 ENSCAFP00000021058.3
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 7.00e-24 83.2 472 501
E3 activity/RING/RING 2.50e-06 28.2 138 176
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 3    tdsvtclaf..sd.tllvsGsdDgtikvWD 29
           +++++c+++     +ll+s+ + gt+ +WD
   Q: 472  NSKISCISWssYHkNLLASSDYEGTVILWD 501
           689******9622599************** PP
   

   E3 activity/RING/RING
   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C+iC++++++  + + CgH f+ +C+++          + rCP C+
   Q: 138  CPICFDMIEE-AYMTKCGHSFCYKCIHQS------LEDNNRCPKCN 176
           ********99.888***********9555......999999****6 PP
   
Organism Canis familiaris
Protein Sequence
(Fasta)
MSGSRQVGSG SAGTSLGSSA ASSVTSASSS LSSSPSPPSV AAAVAVAAAS GGSAQAAGSG 60
GLGGPVARPV LVAAAVSVSG DGAVSASQSR LSCAARPSAG VGGSSSGLGS GSRKRPLLAP 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Cfa-021088|E3,WD_repeat;E3,RING|Canis familiaris
Please wait for a moment...
Nucleotide Sequence
(Fasta)
CTCCCCCTTC CCCCCTTCCC CCCGTACGTC ACCCGCCGCT CGGCTGCGGA CGAGCGCAGC 60
CCGCGTTGCT AGGCCGCCGC CGGGGGCGCG CCGCGCGCGT CCCAGCCGCC CTCGAGGTTG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Cfa-021088|E3,WD_repeat;E3,RING|Canis familiaris
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat
Interpro

IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS
PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
PS00518--ZF_RING_1
PS50089--ZF_RING_2
Pfam

PF00400--WD40
SMART

SM00184--RING
SM00320--WD40
Gene Ontology

GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0032436--P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0010212--P:response to ionizing radiation
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000885 Aegilops tauschii 39.84 2.00e-126 446.00
IUUC-Aml-001265 Ailuropoda melanoleuca 99.51 0.00e+00 1249.00
IUUC-Atr-002460 Amborella trichopoda 38.98 3.00e-126 446.00
IUUC-Apl-003796 Anas platyrhynchos 98.11 0.00e+00 1160.00
IUUC-Aca-005078 Anolis carolinensis 97.26 0.00e+00 1212.00
IUUC-Aly-006014 Arabidopsis lyrata 40.12 1.00e-130 460.00
IUUC-Ath-007636 Arabidopsis thaliana 40.12 8.00e-131 461.00
IUUC-Ame-011176 Astyanax mexicanus 95.87 7.00e-69 254.00
IUUC-Bta-012595 Bos taurus 97.19 0.00e+00 1264.00
IUUC-Bdi-014152 Brachypodium distachyon 39.14 3.00e-129 455.00
IUUC-Bol-016380 Brassica oleracea 40.65 8.00e-131 461.00
IUUC-Bra-017690 Brassica rapa 39.81 2.00e-125 442.00
IUUC-Cja-018926 Callithrix jacchus 98.91 0.00e+00 1258.00
IUUC-Cpo-022442 Cavia porcellus 98.10 0.00e+00 1224.00
IUUC-Cre-022579 Chlamydomonas reinhardtii 33.45 3.00e-33 135.00
IUUC-Csa-024119 Chlorocebus sabaeus 97.23 0.00e+00 1249.00
IUUC-Cho-024883 Choloepus hoffmanni 66.56 2.00e-106 380.00
IUUC-Cin-025375 Ciona intestinalis 54.74 0.00e+00 679.00
IUUC-Cme-027350 Cyanidioschyzon merolae 41.62 8.00e-80 291.00
IUUC-Dre-028453 Danio rerio 87.40 0.00e+00 1084.00
IUUC-Dno-029887 Dasypus novemcinctus 98.75 0.00e+00 1253.00
IUUC-Dor-031110 Dipodomys ordii 80.17 0.00e+00 927.00
IUUC-Ete-033016 Echinops telfairi 84.19 0.00e+00 1042.00
IUUC-Eca-034403 Equus caballus 99.31 0.00e+00 1164.00
IUUC-Eeu-034690 Erinaceus europaeus 82.02 0.00e+00 963.00
IUUC-Fca-036475 Felis catus 98.62 0.00e+00 1165.00
IUUC-Fal-037189 Ficedula albicollis 98.66 0.00e+00 1196.00
IUUC-Gmo-039245 Gadus morhua 86.46 0.00e+00 1057.00
IUUC-Gga-040806 Gallus gallus 98.23 0.00e+00 1241.00
IUUC-Gac-042177 Gasterosteus aculeatus 88.00 0.00e+00 1103.00
IUUC-Gma-044187 Glycine max 40.92 2.00e-127 449.00
IUUC-Ggo-044430 Gorilla gorilla 98.09 0.00e+00 930.00
IUUC-Hsa-045853 Homo sapiens 98.91 0.00e+00 1258.00
IUUC-Hvu-047750 Hordeum vulgare 38.79 1.00e-95 345.00
IUUC-Itr-048238 Ictidomys tridecemlineatus 100.00 5.00e-145 506.00
IUUC-Lch-050420 Latimeria chalumnae 92.04 0.00e+00 1152.00
IUUC-Lpe-051219 Leersia perrieri 38.82 1.00e-124 440.00
IUUC-Loc-052728 Lepisosteus oculatus 91.13 0.00e+00 1106.00
IUUC-Laf-053775 Loxodonta africana 98.28 0.00e+00 1259.00
IUUC-Meu-056595 Macropus eugenii 77.70 3.00e-177 615.00
IUUC-Mtr-058555 Medicago truncatula 40.71 3.00e-134 472.00
IUUC-Mga-059646 Meleagris gallopavo 97.77 0.00e+00 1159.00
IUUC-Mmr-060990 Microcebus murinus 98.90 0.00e+00 1258.00
IUUC-Mdo-062287 Monodelphis domestica 98.71 0.00e+00 1248.00
IUUC-Mmu-064097 Mus musculus 98.61 0.00e+00 1264.00
IUUC-Mac-065240 Musa acuminata 41.22 4.00e-136 478.00
IUUC-Mpu-066612 Mustela putorius furo 98.63 0.00e+00 1167.00
IUUC-Mlu-067967 Myotis lucifugus 96.82 0.00e+00 1168.00
IUUC-Nle-069543 Nomascus leucogenys 99.07 0.00e+00 1262.00
IUUC-Opr-070366 Ochotona princeps 83.18 0.00e+00 712.00
IUUC-Ont-071522 Oreochromis niloticus 84.04 0.00e+00 1093.00
IUUC-Oan-073409 Ornithorhynchus anatinus 98.45 0.00e+00 1162.00
IUUC-Ocu-073756 Oryctolagus cuniculus 98.72 0.00e+00 1229.00
IUUC-Oba-075149 Oryza barthii 38.91 2.00e-127 451.00
IUUC-Obr-076563 Oryza brachyantha 39.48 1.00e-127 450.00
IUUC-Ogl-077701 Oryza glaberrima 38.94 4.00e-128 452.00
IUUC-Ogu-078383 Oryza glumaepatula 38.94 4.00e-128 452.00
IUUC-Oin-079965 Oryza indica 37.05 4.00e-114 405.00
IUUC-Olo-080639 Oryza longistaminata 38.80 1.00e-125 443.00
IUUC-Ome-081821 Oryza meridionalis 38.86 9.00e-116 411.00
IUUC-Oni-082622 Oryza nivara 38.94 4.00e-128 452.00
IUUC-Opu-083295 Oryza punctata 38.64 7.00e-128 451.00
IUUC-Oru-084661 Oryza rufipogon 38.94 4.00e-128 452.00
IUUC-Osa-085766 Oryza sativa 38.94 4.00e-128 452.00
IUUC-Ola-086727 Oryzias latipes 87.50 0.00e+00 1108.00
IUUC-Olu-087702 Ostreococcus lucimarinus 42.86 3.00e-69 254.00
IUUC-Oga-088215 Otolemur garnettii 97.05 0.00e+00 1237.00
IUUC-Oar-089880 Ovis aries 98.58 0.00e+00 1238.00
IUUC-Ptr-090597 Pan troglodytes 98.91 0.00e+00 1258.00
IUUC-Pan-091987 Papio anubis 99.07 0.00e+00 1263.00
IUUC-Psi-094033 Pelodiscus sinensis 98.31 0.00e+00 1173.00
IUUC-Pma-094587 Petromyzon marinus 70.20 0.00e+00 802.00
IUUC-Ppa-095256 Physcomitrella patens 39.64 1.00e-133 470.00
IUUC-Pfo-097388 Poecilia formosa 86.52 0.00e+00 1071.00
IUUC-Pab-098029 Pongo abelii 98.91 0.00e+00 1259.00
IUUC-Pop-099319 Populus trichocarpa 39.38 1.00e-131 463.00
IUUC-Pca-100846 Procavia capensis 90.48 0.00e+00 1143.00
IUUC-Ppe-101250 Prunus persica 38.25 4.00e-121 428.00
IUUC-Pva-102407 Pteropus vampyrus 98.91 0.00e+00 1251.00
IUUC-Rno-105312 Rattus norvegicus 98.60 0.00e+00 1260.00
IUUC-Sha-106514 Sarcophilus harrisii 98.92 0.00e+00 777.00
IUUC-Smo-109418 Selaginella moellendorffii 39.85 3.00e-130 459.00
IUUC-Sit-110248 Setaria italica 38.87 9.00e-129 454.00
IUUC-Sly-110964 Solanum lycopersicum 40.64 1.00e-131 463.00
IUUC-Stu-112882 Solanum tuberosum 40.80 7.00e-133 468.00
IUUC-Sar-113230 Sorex araneus 71.86 0.00e+00 801.00
IUUC-Sbi-113962 Sorghum bicolor 37.01 7.00e-124 437.00
IUUC-Ssc-115987 Sus scrofa 98.52 2.00e-180 624.00
IUUC-Tgu-116471 Taeniopygia guttata 98.22 0.00e+00 1235.00
IUUC-Tru-118231 Takifugu rubripes 87.36 0.00e+00 1055.00
IUUC-Tsy-119415 Tarsius syrichta 98.66 0.00e+00 1175.00
IUUC-Tni-120893 Tetraodon nigroviridis 87.52 0.00e+00 1063.00
IUUC-Tca-121703 Theobroma cacao 41.42 1.00e-130 460.00
IUUC-Tae-125317 Triticum aestivum 40.90 1.00e-134 473.00
IUUC-Tur-126557 Triticum urartu 40.53 2.00e-129 456.00
IUUC-Tbe-127253 Tupaia belangeri 70.94 0.00e+00 852.00
IUUC-Ttr-129100 Tursiops truncatus 97.31 0.00e+00 1143.00
IUUC-Vpa-130613 Vicugna pacos 92.61 0.00e+00 1098.00
IUUC-Vvi-130880 Vitis vinifera 40.97 9.00e-124 437.00
IUUC-Xtr-132033 Xenopus tropicalis 95.33 0.00e+00 1236.00
IUUC-Xma-133421 Xiphophorus maculatus 83.64 0.00e+00 1070.00
Created Date 25-Jun-2017

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