iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ocu-074957

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAGW02027790

Gene Name

KLHL3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOCUG00000007560.3	ENSOCUT00000007561.3	ENSOCUP00000006538.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	6.30e-22	77.8	68	134
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	1.10e-08	34.3	168	194

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgklden 68
           +Dv++v +++e++ah++vLaa+S++F a+f+++++esk  +++eikdv+ + ++ l++++Yt +++ +
   Q: 68   CDVMIVAEDVEIEAHRVVLAACSPYFCAMFTGDMSESK-AKKIEIKDVDGQTLSKLIDYIYTAEIEVT 134
           8*************************************.************************99876 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfi 27
           + Nclgi++fAd ++c+dL ++a+ ++
   Q: 168  PTNCLGIRAFADVHTCTDLLQQANAYA 194
           78**********************997 PP

Organism

Oryctolagus cuniculus

Protein Sequence
(Fasta)

MLDLRTASRL YGFYPDWQRW HLSVKPGSQP PIQAGDDEKN QRTVTVNPAH MGKAFKVMNE 60
LRSKQLLCDV MIVAEDVEIE AHRVVLAACS PYFCAMFTGD MSESKAKKIE IKDVDGQTLS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GATCTATAAA ATAGACTATA TTTGGAATCC AGGCAGCAAA GTAAAACAGA TTTCAGGTAA 60
ATTAGGCTGT ACACATAGCC AAACCAAGCA CTGCTATATG TGATGGGTCT GCAGAAAATT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015916--Gal_Oxidase_b-propeller
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0005829--C:cytosol
GO:0072156--P:distal tubule morphogenesis
GO:0050801--P:ion homeostasis
GO:0070936--P:protein K48-linked ubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0070294--P:renal sodium ion absorption

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001632	Ailuropoda melanoleuca	97.44	0.00e+00	1164.00
IUUC-Apl-003965	Anas platyrhynchos	93.69	0.00e+00	1089.00
IUUC-Aca-004912	Anolis carolinensis	93.68	0.00e+00	1082.00
IUUC-Ame-010670	Astyanax mexicanus	80.24	0.00e+00	929.00
IUUC-Bta-013354	Bos taurus	97.78	0.00e+00	1165.00
IUUC-Bra-017771	Brassica rapa	29.55	9.00e-13	68.90
IUUC-Cel-018136	Caenorhabditis elegans	42.64	1.00e-129	457.00
IUUC-Cja-019183	Callithrix jacchus	93.59	0.00e+00	1019.00
IUUC-Cfa-020465	Canis familiaris	96.74	0.00e+00	1156.00
IUUC-Cpo-022115	Cavia porcellus	97.95	0.00e+00	1167.00
IUUC-Csa-024219	Chlorocebus sabaeus	97.95	0.00e+00	1163.00
IUUC-Csv-026032	Ciona savignyi	60.40	0.00e+00	692.00
IUUC-Cgl-026620	Colletotrichum gloeosporioides	30.42	1.00e-24	107.00
IUUC-Dre-028524	Danio rerio	74.64	0.00e+00	943.00
IUUC-Dno-029075	Dasypus novemcinctus	98.23	0.00e+00	1125.00
IUUC-Dor-030156	Dipodomys ordii	88.56	0.00e+00	744.00
IUUC-Ete-033064	Echinops telfairi	82.58	0.00e+00	850.00
IUUC-Eca-033887	Equus caballus	97.40	0.00e+00	1145.00
IUUC-Eeu-035244	Erinaceus europaeus	78.29	0.00e+00	914.00
IUUC-Fca-035375	Felis catus	97.10	0.00e+00	1158.00
IUUC-Fal-037119	Ficedula albicollis	95.33	0.00e+00	1053.00
IUUC-Fso-038219	Fusarium solani	40.32	2.00e-10	57.00
IUUC-Gga-041094	Gallus gallus	95.12	0.00e+00	1088.00
IUUC-Gac-042585	Gasterosteus aculeatus	76.18	0.00e+00	897.00
IUUC-Ggo-045485	Gorilla gorilla	97.96	0.00e+00	1161.00
IUUC-Hsa-046717	Homo sapiens	98.29	0.00e+00	1165.00
IUUC-Itr-048605	Ictidomys tridecemlineatus	98.29	0.00e+00	1165.00
IUUC-Lch-050246	Latimeria chalumnae	86.01	0.00e+00	985.00
IUUC-Laf-053700	Loxodonta africana	96.25	0.00e+00	1146.00
IUUC-Mcc-054732	Macaca mulatta	98.82	0.00e+00	1011.00
IUUC-Mga-059994	Meleagris gallopavo	94.14	0.00e+00	982.00
IUUC-Mdo-062923	Monodelphis domestica	96.07	0.00e+00	1144.00
IUUC-Mmu-063842	Mus musculus	97.10	0.00e+00	1152.00
IUUC-Mpu-066380	Mustela putorius furo	96.92	0.00e+00	1154.00
IUUC-Mlu-067922	Myotis lucifugus	97.40	0.00e+00	1143.00
IUUC-Nle-069761	Nomascus leucogenys	97.95	0.00e+00	1163.00
IUUC-Opr-070287	Ochotona princeps	89.23	0.00e+00	1036.00
IUUC-Ont-071654	Oreochromis niloticus	79.15	0.00e+00	945.00
IUUC-Ola-086853	Oryzias latipes	77.78	0.00e+00	897.00
IUUC-Oga-088559	Otolemur garnettii	97.27	0.00e+00	1159.00
IUUC-Oar-089925	Ovis aries	97.95	0.00e+00	1166.00
IUUC-Ptr-091487	Pan troglodytes	98.29	0.00e+00	1165.00
IUUC-Pan-091705	Papio anubis	97.95	0.00e+00	1163.00
IUUC-Psi-093478	Pelodiscus sinensis	91.18	0.00e+00	1043.00
IUUC-Pfo-097450	Poecilia formosa	78.95	0.00e+00	888.00
IUUC-Pab-097618	Pongo abelii	98.12	0.00e+00	1163.00
IUUC-Pca-100739	Procavia capensis	88.00	0.00e+00	652.00
IUUC-Sha-106935	Sarcophilus harrisii	98.13	0.00e+00	748.00
IUUC-Ssc-115599	Sus scrofa	97.77	0.00e+00	1162.00
IUUC-Tgu-117001	Taeniopygia guttata	94.89	0.00e+00	1072.00
IUUC-Tru-118078	Takifugu rubripes	78.18	0.00e+00	936.00
IUUC-Tsy-119161	Tarsius syrichta	85.98	0.00e+00	896.00
IUUC-Tni-120888	Tetraodon nigroviridis	76.00	0.00e+00	876.00
IUUC-Tbe-127285	Tupaia belangeri	84.30	0.00e+00	665.00
IUUC-Ttr-128884	Tursiops truncatus	83.14	1.00e-151	530.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence