iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress	GXD
DNA & RNA Element
microRNA	TRANSFAC	RepTar	RAID2
Protein-protein Interaction
IID
Post-translational Modifications (PTMs)
dbPTM
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	1.50e-17	64.8	35	98
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	1.40e-12	46.6	134	165

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgkl 65
           +D+il vg+++++ahk+vLa+ S++F+a+f+++l+e++ +++ve++ ++  +++a++++ Ytg++
   Q: 35   CDIILRVGDVKIHAHKVVLASISPYFKAMFTGNLSEKE-NSEVEFQCIDEAALQAIVEYAYTGTV 98
           8***********************************97.************************87 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfilkhFk 32
           + Nc+gi rfA++y+c+dL++aa +fi+++F+
   Q: 134  PGNCIGISRFAETYGCHDLYLAATKFICQNFE 165
           56*****************************5 PP

Organism

Mus musculus

Protein Sequence
(Fasta)

MDHTAPTYML ANLTHLHSEQ LLQGLNLLRQ HHELCDIILR VGDVKIHAHK VVLASISPYF 60
KAMFTGNLSE KENSEVEFQC IDEAALQAIV EYAYTGTVFI SQDTVESLLP AANLLQIKLV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGGGCGGAAG TTTTCCACCC CACCCATAAG AGTTGAGGTT TGACGGGAGC AAGAGAGGAT 60
CCCATCCCGG GTTCCAGTTT TCCGTGGCTC CTCCTCCTGT TGCTGCAGGT GTTATTCCTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0025--Alternative splicing
KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR011043--Gal_Oxase/kelch_b-propeller
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR030569--KLHL28
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0016567--P:protein ubiquitination

KEGG

mmu:66689

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001581	Ailuropoda melanoleuca	97.20	0.00e+00	1176.00
IUUC-Apl-003577	Anas platyrhynchos	91.71	0.00e+00	1081.00
IUUC-Aca-004320	Anolis carolinensis	86.37	0.00e+00	926.00
IUUC-Ame-011433	Astyanax mexicanus	84.24	0.00e+00	984.00
IUUC-Bta-012650	Bos taurus	97.37	0.00e+00	1177.00
IUUC-Cja-019878	Callithrix jacchus	96.85	0.00e+00	1177.00
IUUC-Cfa-020936	Canis familiaris	97.37	0.00e+00	1177.00
IUUC-Cpo-022212	Cavia porcellus	95.97	0.00e+00	1164.00
IUUC-Csa-023372	Chlorocebus sabaeus	97.20	0.00e+00	1177.00
IUUC-Cho-024885	Choloepus hoffmanni	97.32	5.00e-173	600.00
IUUC-Dno-029895	Dasypus novemcinctus	95.97	0.00e+00	1163.00
IUUC-Ete-032703	Echinops telfairi	95.97	0.00e+00	907.00
IUUC-Eca-034150	Equus caballus	97.20	0.00e+00	1176.00
IUUC-Eeu-035233	Erinaceus europaeus	95.45	0.00e+00	1158.00
IUUC-Fca-036445	Felis catus	97.02	0.00e+00	1173.00
IUUC-Fal-037156	Ficedula albicollis	81.61	0.00e+00	993.00
IUUC-Gmo-039158	Gadus morhua	84.59	0.00e+00	1018.00
IUUC-Gga-040855	Gallus gallus	91.59	0.00e+00	1113.00
IUUC-Gac-041294	Gasterosteus aculeatus	83.01	0.00e+00	1000.00
IUUC-Ggo-045399	Gorilla gorilla	97.02	0.00e+00	1172.00
IUUC-Hsa-046199	Homo sapiens	97.02	0.00e+00	1172.00
IUUC-Itr-048859	Ictidomys tridecemlineatus	96.85	0.00e+00	1169.00
IUUC-Lch-049445	Latimeria chalumnae	87.70	0.00e+00	811.00
IUUC-Loc-052737	Lepisosteus oculatus	86.16	0.00e+00	1015.00
IUUC-Laf-054173	Loxodonta africana	96.50	0.00e+00	1164.00
IUUC-Mcc-055000	Macaca mulatta	97.20	0.00e+00	1176.00
IUUC-Meu-056028	Macropus eugenii	87.29	1.00e-145	509.00
IUUC-Mga-059609	Meleagris gallopavo	91.43	0.00e+00	1109.00
IUUC-Mmr-060842	Microcebus murinus	97.37	0.00e+00	1176.00
IUUC-Mdo-062776	Monodelphis domestica	91.94	0.00e+00	1081.00
IUUC-Mpu-066594	Mustela putorius furo	67.01	0.00e+00	721.00
IUUC-Mlu-067403	Myotis lucifugus	95.80	0.00e+00	1157.00
IUUC-Nle-069242	Nomascus leucogenys	96.85	0.00e+00	1172.00
IUUC-Opr-070942	Ochotona princeps	97.99	6.00e-176	609.00
IUUC-Ont-072586	Oreochromis niloticus	84.59	0.00e+00	1015.00
IUUC-Oan-073070	Ornithorhynchus anatinus	92.32	0.00e+00	1074.00
IUUC-Ocu-074536	Oryctolagus cuniculus	97.02	0.00e+00	1171.00
IUUC-Ola-086669	Oryzias latipes	72.19	0.00e+00	830.00
IUUC-Oga-088974	Otolemur garnettii	97.37	0.00e+00	1177.00
IUUC-Oar-089544	Ovis aries	97.20	0.00e+00	1179.00
IUUC-Ptr-091478	Pan troglodytes	96.67	0.00e+00	1164.00
IUUC-Pan-092653	Papio anubis	97.37	0.00e+00	1177.00
IUUC-Psi-094014	Pelodiscus sinensis	92.29	0.00e+00	1123.00
IUUC-Pfo-097316	Poecilia formosa	84.06	0.00e+00	1009.00
IUUC-Pab-098609	Pongo abelii	96.85	0.00e+00	1170.00
IUUC-Pva-102527	Pteropus vampyrus	97.66	2.00e-174	605.00
IUUC-Rno-105188	Rattus norvegicus	98.42	0.00e+00	1183.00
IUUC-Sha-106543	Sarcophilus harrisii	92.47	0.00e+00	1087.00
IUUC-Sar-113507	Sorex araneus	94.75	0.00e+00	1153.00
IUUC-Ssc-115803	Sus scrofa	97.37	0.00e+00	1176.00
IUUC-Tgu-116661	Taeniopygia guttata	81.56	0.00e+00	912.00
IUUC-Tru-118738	Takifugu rubripes	81.22	0.00e+00	977.00
IUUC-Tsy-119570	Tarsius syrichta	89.49	0.00e+00	1062.00
IUUC-Tni-120041	Tetraodon nigroviridis	82.66	0.00e+00	999.00
IUUC-Tbe-127655	Tupaia belangeri	90.21	0.00e+00	1053.00
IUUC-Ttr-129249	Tursiops truncatus	97.37	0.00e+00	1178.00
IUUC-Vpa-130034	Vicugna pacos	97.02	0.00e+00	1174.00
IUUC-Xtr-132964	Xenopus tropicalis	86.51	0.00e+00	1053.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence