iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPPYG00000020290.2	ENSPPYT00000023670.1	ENSPPYP00000022708.1
ENSPPYG00000020290.2	ENSPPYT00000023671.2	ENSPPYP00000022709.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	2.00e-107	359.4	277	876

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgye 88
           +Gl+NlgNtC+mNS+LQcLsn+p+l+e++l+  + e+ln +np ++kge+++++++l+++ w+++++++ p+ ++++++++a++f gy+
   Q: 277  CGLTNLGNTCFMNSALQCLSNVPQLTEYFLNnCYLEELNFRNPLGMKGEIAEAYADLVKQAWSGHHRSIVPHVFKNKVGHFASQFLGYQ 365
           7******************************99******************************************************** PP
   S: 89   qqDaqEflaflldqleeelkkeknkpkeeeeeedkselsde...aeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlsl 174
           q+D+qE+l+flld+l+e+l++ k+k++ e+++++ +  ++    a++++k++n+s+i+d F+g +ks+++c++c+nvs++++pf++ls+
   Q: 366  QHDSQELLSFLLDGLHEDLNRVKKKEYVELCDAAGRPDQEVaqeAWQNHKRRNDSVIVD-FHGLFKSTLVCPDCGNVSVTFDPFCYLSV 453
           *****************************998874333322555**************9.9**************************** PP
   S: 175  pvpgkeetkke.............................................................................. 185
           p+p ++++ +e                                                                              
   Q: 454  PLPISHKRVLEvffipmdprrkpeqvwavgawgdddghiemsgwgsqrrvreslgalqvcllstphsyevsgrieaiegsredivvpvy 542
           ******99888****************************************************************************** PP
   S: 186  ......................................................................................... 185
                                                                                                    
   Q: 543  rertpardynnsyyglmlfghpllgisapgtaspgkglynvmyrlsryvtkpnsddeddgdekeddeedkddvpgstggslrdpepeqa 631
           ***************************************************************************************** PP
   S: 186  ......................................................................................... 185
                                                                                                    
   Q: 632  gpssgvtnrcpflldnclgtsqwpprrrrkqlftlqtvnsngtsdrttspeevhaqpyiaidwepemkkryydeveaegyvhdtcvgyv 720
           ***************************************************************************************** PP
   S: 186  ......slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefple.Ldlspfcts 267
                  lq+c+e ft+ e+le+en +yc++ck++q a+kkl+l+ lPe+Li+hLkRfs+++   srek+++ vefp++ Ld s+f+++
   Q: 721  mkkapvRLQECIELFTTVETLEKENPWYCPSCKQHQLATKKLDLWMLPEILIIHLKRFSYTK--FSREKLDTLVEFPIRdLDFSEFVIQ 807
           **********************************************************8866..89********************999 PP
   S: 268  peekqke.kkkYeLiavvvHsGslssGHYvayvknekgkWllfdDskVtevkeeevleetgstaYvlfYkrr 338
           p+++++   +kY+Liav +H+G+++ GHY++++ + +g+W +fdD++V +  e++++    + aYvlfY+r+
   Q: 808  PQNDSNPeLYKYDLIAVSNHYGGMRDGHYTTFACKGSGQWHYFDDNSVYVN-ENQIEV--LKAAYVLFYQRQ 876
           9887654489**************************************977.455555..269*******96 PP

Organism

Pongo abelii

Protein Sequence
(Fasta)

SCVGCRGERT AMATVAANPA AAAAAVAAAA AVAEDKEPQH EELPGLDSQW RQIENGESGR 60
ERPLRAGESW FLVEKHWYKQ WEAYVQGGDQ DSSTFPGCIN NATLFQDEIN WRLKEGLVEG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCAGTAG CCCCGCGACT GTTTGGGGGG CTCTGCTTCC GTTTCCGGGA CCAGAATCCG 60
GAAGTGGCTG TTGAGGGGCG TCTTCCAATC TCGCACAGCT GCGTTGGCTG TAGAGGAGAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR006615--Pept_C19_DUSP
IPR001394--Peptidase_C19_UCH
IPR028135--Ub_USP-typ
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS51283--DUSP
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF06337--DUSP
PF14836--Ubiquitin_3
PF00443--UCH

SMART

SM00695--DUSP

Gene Ontology

GO:0005829--C:cytosol
GO:0005654--C:nucleoplasm
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001760	Ailuropoda melanoleuca	75.78	0.00e+00	1278.00
IUUC-Aca-004532	Anolis carolinensis	59.66	0.00e+00	956.00
IUUC-Bta-013284	Bos taurus	74.67	0.00e+00	1266.00
IUUC-Cja-019746	Callithrix jacchus	88.00	0.00e+00	1470.00
IUUC-Cfa-020134	Canis familiaris	76.85	0.00e+00	1323.00
IUUC-Cpo-022535	Cavia porcellus	75.41	0.00e+00	1324.00
IUUC-Csa-023828	Chlorocebus sabaeus	90.89	0.00e+00	1554.00
IUUC-Dno-028853	Dasypus novemcinctus	75.03	0.00e+00	1071.00
IUUC-Dor-030384	Dipodomys ordii	77.53	0.00e+00	1311.00
IUUC-Eca-033271	Equus caballus	76.27	0.00e+00	1293.00
IUUC-Fca-036012	Felis catus	76.27	0.00e+00	1314.00
IUUC-Hsa-046551	Homo sapiens	91.21	0.00e+00	1554.00
IUUC-Itr-048915	Ictidomys tridecemlineatus	77.83	0.00e+00	1339.00
IUUC-Kpa-049332	Komagataella pastoris	37.80	9.00e-67	248.00
IUUC-Laf-054561	Loxodonta africana	73.84	0.00e+00	1298.00
IUUC-Mcc-054881	Macaca mulatta	90.46	0.00e+00	1549.00
IUUC-Meu-056749	Macropus eugenii	67.47	0.00e+00	714.00
IUUC-Mmr-061400	Microcebus murinus	83.50	0.00e+00	1444.00
IUUC-Mdo-062470	Monodelphis domestica	77.02	0.00e+00	660.00
IUUC-Mmu-063241	Mus musculus	74.55	0.00e+00	1297.00
IUUC-Mpu-066507	Mustela putorius furo	76.19	0.00e+00	1319.00
IUUC-Mlu-066961	Myotis lucifugus	69.99	0.00e+00	1168.00
IUUC-Nle-069284	Nomascus leucogenys	91.00	0.00e+00	1547.00
IUUC-Ont-071847	Oreochromis niloticus	52.32	0.00e+00	854.00
IUUC-Oan-073387	Ornithorhynchus anatinus	63.24	0.00e+00	1048.00
IUUC-Ocu-074066	Oryctolagus cuniculus	81.83	0.00e+00	1387.00
IUUC-Oga-088424	Otolemur garnettii	82.93	0.00e+00	1431.00
IUUC-Oar-089732	Ovis aries	71.60	0.00e+00	1238.00
IUUC-Pan-092292	Papio anubis	89.82	0.00e+00	1547.00
IUUC-Pca-100851	Procavia capensis	80.27	0.00e+00	754.00
IUUC-Pva-103244	Pteropus vampyrus	74.64	0.00e+00	1264.00
IUUC-Rno-105100	Rattus norvegicus	74.89	0.00e+00	1295.00
IUUC-Sha-107502	Sarcophilus harrisii	66.73	0.00e+00	714.00
IUUC-Ssc-116345	Sus scrofa	76.07	0.00e+00	1316.00
IUUC-Tru-117788	Takifugu rubripes	51.46	0.00e+00	783.00
IUUC-Tsy-119414	Tarsius syrichta	76.53	0.00e+00	1014.00
IUUC-Tbe-128081	Tupaia belangeri	79.04	0.00e+00	826.00
IUUC-Ttr-128502	Tursiops truncatus	72.54	0.00e+00	1222.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence