iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Laf-053752

UUCD1 version

UUC-LoA-01106

Ensembl Protein ID

ENSLAFP00000011296.3

UniProt Accession

G3TBE7; G3TBE7_LOXAF

Protein Name

Uncharacterized protein

Gene Name

USP30

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000013502.3	ENSLAFT00000013502.3	ENSLAFP00000011296.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	3.80e-70	237.1	42	474

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelw...kskkkavsprellkalkkeaeefsgy 87
           Gl NlgNtC+mNS+LQ Ls++p + + l e +++ +++ +++ p++ l+ +l +l+++l     +++++ + + ll++l+++  ++s++
   Q: 42   GLLNLGNTCFMNSLLQGLSACPTFIKWLEEFTSQYTRDPKEPPPHQYLSLTLLHLLKALScqeVTDDEVLDASCLLDVLRMYRWQISSF 130
           9*****************************6666667777788999*************888899999********************* PP
   S: 88   eqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsde..........aeekkkkknkslisdlFqgqlksqikclecdnvs.sr 165
           e+qDa+E+++++ ++le+e    ++ +++++++ ++ e+++e          + + ++++++   ++ F+g+l+s+++c++c+++s +r
   Q: 131  EEQDAHELFHVITSSLEDER--DRQPRVTHLFDVHSLEQQSEitpkqitcrtRGSPHPTSGHWKSQHPFHGRLTSNMVCKHCEHQSpVR 217
           *******************9..6688888899988888888889999999999999********************************* PP
   S: 166  eepfldlslpvpgkeetkkeslqdcLesftkeeelegenkyycekck...............kkqeaekklklkklPevLilhLkRfsf 239
           +++f +lsl++p  +  ++++l++cL++f + e++++   + c++c+               ++++ +k+lkl klP++L++hL+R s+
   Q: 218  FDTFDSLSLSIPAATWGHPLTLDHCLHHFISSESVRD---VVCDNCTkieakgvlngekvehQRTTFVKQLKLGKLPQCLCIHLQRLSW 303
           ***********************************97...9******8888888888888777777*********************** PP
   S: 240  seeqksrekinkkvefple..Ldlspfcts..................................peekqke.................. 274
           s++ + + k +++v+f++   Ld+ ++                                     p                        
   Q: 304  SSH-GTPLKRHEHVQFNEFliLDIYKYRLLghkpgqrkpvlsdgtgpasepqdgpaapkpvlnqP-----Gapktqvfmngacspsllp 386
           998.8888*********773366666554466766666666666666666655555555555550.....0555555555566666666 PP
   S: 275  ...................kkkYeLiavvvHsGslssGHYvayvkn.........ekgkWllfdDskVtevkeeevleetgstaYvlfY 335
                              ++ ++L+avvvH+G ++sGH+v+y ++         ++ +Wl ++D++V++ + +evl+   s+aY+lfY
   Q: 387  tlptpmtfplpvvpdysssTYLFRLMAVVVHHGDMHSGHFVTYRRSppsaknplsTSSQWLWISDDTVRKASLQEVLS---SSAYLLFY 472
           66666666666666666559999***********************9988888877888*******************...******** PP
   S: 336  kr 337
           +r
   Q: 473  ER 474
           98 PP

Organism

Loxodonta africana

Protein Sequence
(Fasta)

RYKVMKNWGV IGGIAAALAA GIYVIWGPIT ERKKRRKGLV PGLLNLGNTC FMNSLLQGLS 60
ACPTFIKWLE EFTSQYTRDP KEPPPHQYLS LTLLHLLKAL SCQEVTDDEV LDASCLLDVL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGATACAAAG TCATGAAGAA CTGGGGAGTT ATTGGTGGTA TTGCCGCTGC GCTTGCAGCA 60
GGAATATATG TTATTTGGGG GCCCATTACA GAAAGAAAGA AGCGTAGAAA AGGTAAGAAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0016021--C:integral component of membrane
GO:0005741--C:mitochondrial outer membrane
GO:0004197--F:cysteine-type endopeptidase activity
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0008053--P:mitochondrial fusion
GO:0000422--P:mitophagy
GO:0035871--P:protein K11-linked deubiquitination
GO:0044313--P:protein K6-linked deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000204	Aegilops tauschii	26.76	7.00e-18	85.10
IUUC-Aml-001733	Ailuropoda melanoleuca	91.28	0.00e+00	829.00
IUUC-Atr-002510	Amborella trichopoda	25.00	2.00e-21	97.10
IUUC-Apl-003645	Anas platyrhynchos	71.12	3.00e-105	374.00
IUUC-Aca-004583	Anolis carolinensis	68.42	2.00e-24	103.00
IUUC-Aly-005754	Arabidopsis lyrata	25.83	2.00e-25	110.00
IUUC-Ath-007622	Arabidopsis thaliana	26.04	1.00e-23	103.00
IUUC-Ani-009286	Aspergillus nidulans	21.36	9.00e-12	65.50
IUUC-Ame-010896	Astyanax mexicanus	61.81	1.00e-154	539.00
IUUC-Bta-012321	Bos taurus	91.43	0.00e+00	833.00
IUUC-Bdi-014795	Brachypodium distachyon	26.65	1.00e-15	77.40
IUUC-Bol-015637	Brassica oleracea	27.09	3.00e-23	103.00
IUUC-Bra-016801	Brassica rapa	26.51	1.00e-24	107.00
IUUC-Cel-018308	Caenorhabditis elegans	28.39	1.00e-35	144.00
IUUC-Cja-018826	Callithrix jacchus	92.46	0.00e+00	881.00
IUUC-Cfa-021206	Canis familiaris	91.89	0.00e+00	835.00
IUUC-Cpo-021343	Cavia porcellus	91.22	0.00e+00	824.00
IUUC-Csa-023419	Chlorocebus sabaeus	92.65	0.00e+00	883.00
IUUC-Cho-024475	Choloepus hoffmanni	88.73	2.00e-135	475.00
IUUC-Cgl-026621	Colletotrichum gloeosporioides	22.58	2.00e-13	71.20
IUUC-Cne-027061	Cryptococcus neoformans	24.71	5.00e-10	59.70
IUUC-Dre-027563	Danio rerio	59.79	8.00e-153	533.00
IUUC-Dno-029929	Dasypus novemcinctus	91.84	0.00e+00	845.00
IUUC-Dor-030166	Dipodomys ordii	80.82	0.00e+00	708.00
IUUC-Dse-031517	Dothistroma septosporum	22.72	2.00e-11	63.90
IUUC-Dme-031627	Drosophila melanogaster	33.21	4.00e-34	139.00
IUUC-Ete-032634	Echinops telfairi	80.20	0.00e+00	674.00
IUUC-Eca-033968	Equus caballus	92.86	0.00e+00	836.00
IUUC-Eeu-035279	Erinaceus europaeus	81.71	1.00e-58	220.00
IUUC-Fca-036525	Felis catus	92.24	0.00e+00	860.00
IUUC-Fal-036606	Ficedula albicollis	74.74	5.00e-160	556.00
IUUC-Gmo-038726	Gadus morhua	57.63	2.00e-138	485.00
IUUC-Gga-040718	Gallus gallus	74.56	9.00e-160	556.00
IUUC-Gac-042645	Gasterosteus aculeatus	58.06	2.00e-146	512.00
IUUC-Gma-042890	Glycine max	25.93	2.00e-27	117.00
IUUC-Ggo-045021	Gorilla gorilla	92.65	0.00e+00	881.00
IUUC-Hsa-045832	Homo sapiens	92.65	0.00e+00	881.00
IUUC-Itr-048392	Ictidomys tridecemlineatus	93.47	0.00e+00	850.00
IUUC-Lch-050662	Latimeria chalumnae	70.55	1.00e-179	622.00
IUUC-Lpe-051078	Leersia perrieri	27.70	2.00e-30	126.00
IUUC-Loc-052611	Lepisosteus oculatus	67.08	2.00e-174	605.00
IUUC-Lma-053048	Leptosphaeria maculans	20.24	1.00e-15	78.20
IUUC-Mcc-054892	Macaca mulatta	93.06	0.00e+00	886.00
IUUC-Meu-056673	Macropus eugenii	74.67	3.00e-161	561.00
IUUC-Mtr-057976	Medicago truncatula	26.80	2.00e-34	140.00
IUUC-Mla-058970	Melampsora laricipopulina	22.56	5.00e-19	89.00
IUUC-Mga-059543	Meleagris gallopavo	75.60	0.00e+00	657.00
IUUC-Mmr-061534	Microcebus murinus	92.24	0.00e+00	853.00
IUUC-Mdo-062140	Monodelphis domestica	69.17	5.00e-167	580.00
IUUC-Mmu-063673	Mus musculus	88.57	0.00e+00	804.00
IUUC-Mpu-066328	Mustela putorius furo	91.84	0.00e+00	842.00
IUUC-Mlu-067938	Myotis lucifugus	92.24	0.00e+00	855.00
IUUC-Nle-069426	Nomascus leucogenys	91.63	0.00e+00	813.00
IUUC-Opr-070796	Ochotona princeps	85.21	3.00e-122	431.00
IUUC-Ont-072248	Oreochromis niloticus	61.63	3.00e-152	531.00
IUUC-Oan-072916	Ornithorhynchus anatinus	82.04	0.00e+00	754.00
IUUC-Ocu-074459	Oryctolagus cuniculus	87.18	0.00e+00	661.00
IUUC-Oba-075765	Oryza barthii	26.69	5.00e-28	119.00
IUUC-Obr-076005	Oryza brachyantha	27.08	1.00e-31	131.00
IUUC-Ogl-077916	Oryza glaberrima	27.79	2.00e-31	130.00
IUUC-Ogu-078263	Oryza glumaepatula	26.83	8.00e-29	121.00
IUUC-Oin-080096	Oryza indica	26.42	3.00e-22	99.80
IUUC-Ome-081928	Oryza meridionalis	27.43	1.00e-29	124.00
IUUC-Oni-082424	Oryza nivara	26.69	8.00e-29	121.00
IUUC-Oru-085117	Oryza rufipogon	26.69	8.00e-29	121.00
IUUC-Ola-087429	Oryzias latipes	57.23	6.00e-140	490.00
IUUC-Oga-087981	Otolemur garnettii	92.24	0.00e+00	848.00
IUUC-Oar-089927	Ovis aries	91.22	0.00e+00	830.00
IUUC-Ptr-090878	Pan troglodytes	92.65	0.00e+00	881.00
IUUC-Pan-092698	Papio anubis	93.06	0.00e+00	886.00
IUUC-Psi-093451	Pelodiscus sinensis	77.13	0.00e+00	714.00
IUUC-Ppa-096015	Physcomitrella patens	27.13	1.00e-10	61.60
IUUC-Pfo-096096	Poecilia formosa	58.73	6.00e-150	523.00
IUUC-Pab-098676	Pongo abelii	91.22	0.00e+00	858.00
IUUC-Pca-100418	Procavia capensis	95.79	4.00e-129	454.00
IUUC-Ppe-101898	Prunus persica	24.85	4.00e-26	112.00
IUUC-Pva-103018	Pteropus vampyrus	90.82	0.00e+00	818.00
IUUC-Pgr-103686	Puccinia graminis	21.55	6.00e-13	69.30
IUUC-Ptt-103779	Puccinia triticina	20.88	4.00e-13	70.50
IUUC-Pte-104330	Pyrenophora teres	22.12	4.00e-16	79.70
IUUC-Pyt-104518	Pyrenophora triticirepentis	21.46	5.00e-18	86.30
IUUC-Rno-105708	Rattus norvegicus	87.76	0.00e+00	793.00
IUUC-Sha-106971	Sarcophilus harrisii	81.95	0.00e+00	759.00
IUUC-Sit-110442	Setaria italica	26.88	6.00e-29	122.00
IUUC-Ssc-116397	Sus scrofa	90.61	0.00e+00	822.00
IUUC-Tgu-117446	Taeniopygia guttata	70.10	0.00e+00	642.00
IUUC-Tru-118268	Takifugu rubripes	59.54	3.00e-139	488.00
IUUC-Tsy-119484	Tarsius syrichta	88.98	7.00e-53	201.00
IUUC-Tni-119735	Tetraodon nigroviridis	56.79	2.00e-119	422.00
IUUC-Tca-121660	Theobroma cacao	25.70	7.00e-30	125.00
IUUC-Tae-125383	Triticum aestivum	27.52	9.00e-28	118.00
IUUC-Tur-126458	Triticum urartu	26.52	1.00e-20	94.70
IUUC-Tbe-127740	Tupaia belangeri	85.71	0.00e+00	759.00
IUUC-Ttr-129273	Tursiops truncatus	89.59	0.00e+00	805.00
IUUC-Vda-129789	Verticillium dahliae	23.49	7.00e-10	59.30
IUUC-Vvi-131177	Vitis vinifera	24.86	1.00e-26	114.00
IUUC-Xtr-132374	Xenopus tropicalis	66.87	2.00e-172	598.00
IUUC-Xma-133267	Xiphophorus maculatus	61.19	1.00e-152	532.00
IUUC-Yli-134571	Yarrowia lipolytica	24.09	2.00e-11	64.30
IUUC-Zma-135796	Zea mays	26.95	3.00e-26	112.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence