iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Laf-053498

UUCD1 version

UUC-LoA-00927

Ensembl Protein ID

ENSLAFP00000027736.1

UniProt Accession

G3UIS8; G3UIS8_LOXAF

Protein Name

Uncharacterized protein

Gene Name

KLHL25

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLAFG00000010540.3	ENSLAFT00000010539.3	ENSLAFP00000027736.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	4.50e-20	72.2	46	114
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	5.60e-09	35.2	146	177

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikd.vqpevfrallkFlYtgkldene 69
           +Dv+l  g++ f++h++vLaasS++F+a+f+++l+es+  ++v+++d + pev++ ll+F Y++++ +ne
   Q: 46   TDVTLWAGDRAFPCHRAVLAASSRYFEAMFSHGLRESR-DDTVNFQDnLHPEVLELLLDFAYSSRIAINE 114
           7*************************************.*******99*****************99987 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfilkhFk 32
           ++Nclg++ ++d+++c++L+++  +++l hF+
   Q: 146  PSNCLGMMLLSDAHQCRRLYEFSWRMCLVHFE 177
           89*****************************5 PP

Organism

Loxodonta africana

Protein Sequence
(Fasta)

MSVSVHETRK SRSSTGSMNI TLFHKASHPD CVLAHLNTLR KHRMFTDVTL WAGDRAFPCH 60
RAVLAASSRY FEAMFSHGLR ESRDDTVNFQ DNLHPEVLEL LLDFAYSSRI AINEENAESL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCCGTCA GCGTCCACGA GACCCGCAAG TCGCGGAGCA GCACAGGCTC CATGAACATC 60
ACGCTCTTCC ACAAGGCCTC CCACCCCGAC TGTGTGCTGG CCCACCTCAA CACGCTGCGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015916--Gal_Oxidase_b-propeller
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR030565--KLHL25
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0005737--C:cytoplasm
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0006446--P:regulation of translational initiation

KEGG

lav:100677287

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002373	Ailuropoda melanoleuca	96.26	0.00e+00	1189.00
IUUC-Apl-003543	Anas platyrhynchos	90.68	0.00e+00	1094.00
IUUC-Aca-004729	Anolis carolinensis	87.44	0.00e+00	1073.00
IUUC-Ame-011020	Astyanax mexicanus	84.55	0.00e+00	1027.00
IUUC-Bta-012955	Bos taurus	95.25	0.00e+00	1182.00
IUUC-Cja-018839	Callithrix jacchus	95.42	0.00e+00	1181.00
IUUC-Cfa-020224	Canis familiaris	96.94	0.00e+00	1200.00
IUUC-Cpo-021593	Cavia porcellus	92.87	0.00e+00	1110.00
IUUC-Csa-023276	Chlorocebus sabaeus	96.10	0.00e+00	1188.00
IUUC-Dre-028053	Danio rerio	85.06	0.00e+00	1005.00
IUUC-Dno-029287	Dasypus novemcinctus	93.89	0.00e+00	1164.00
IUUC-Dor-030908	Dipodomys ordii	87.61	0.00e+00	1064.00
IUUC-Dse-031490	Dothistroma septosporum	28.37	2.00e-05	42.40
IUUC-Fca-035897	Felis catus	96.10	0.00e+00	1188.00
IUUC-Fal-037036	Ficedula albicollis	90.83	0.00e+00	1100.00
IUUC-Gmo-039345	Gadus morhua	84.55	0.00e+00	999.00
IUUC-Gga-040404	Gallus gallus	90.66	0.00e+00	1101.00
IUUC-Gac-042447	Gasterosteus aculeatus	84.89	0.00e+00	1020.00
IUUC-Ggo-045060	Gorilla gorilla	95.93	0.00e+00	1186.00
IUUC-Hsa-046494	Homo sapiens	95.93	0.00e+00	1186.00
IUUC-Itr-047993	Ictidomys tridecemlineatus	96.94	0.00e+00	1199.00
IUUC-Lch-050211	Latimeria chalumnae	86.22	0.00e+00	1046.00
IUUC-Loc-052578	Lepisosteus oculatus	84.89	0.00e+00	1036.00
IUUC-Lma-053168	Leptosphaeria maculans	29.79	6.00e-05	41.60
IUUC-Mcc-055033	Macaca mulatta	96.26	0.00e+00	1189.00
IUUC-Meu-056893	Macropus eugenii	92.70	0.00e+00	1145.00
IUUC-Mga-060025	Meleagris gallopavo	90.83	0.00e+00	1100.00
IUUC-Mmr-060658	Microcebus murinus	95.59	0.00e+00	1185.00
IUUC-Mdo-062667	Monodelphis domestica	92.70	0.00e+00	1147.00
IUUC-Mmu-063125	Mus musculus	93.72	0.00e+00	1126.00
IUUC-Mpu-066209	Mustela putorius furo	96.10	0.00e+00	1190.00
IUUC-Mlu-068237	Myotis lucifugus	93.21	0.00e+00	1126.00
IUUC-Nle-069454	Nomascus leucogenys	95.88	0.00e+00	1172.00
IUUC-Ont-072138	Oreochromis niloticus	85.06	0.00e+00	1008.00
IUUC-Oan-073320	Ornithorhynchus anatinus	86.25	0.00e+00	1071.00
IUUC-Ocu-073765	Oryctolagus cuniculus	89.64	0.00e+00	1098.00
IUUC-Oga-088002	Otolemur garnettii	95.76	0.00e+00	1183.00
IUUC-Oar-089481	Ovis aries	94.57	0.00e+00	1176.00
IUUC-Ptr-091200	Pan troglodytes	95.76	0.00e+00	1181.00
IUUC-Psi-093884	Pelodiscus sinensis	89.98	0.00e+00	1088.00
IUUC-Pno-095143	Phaeosphaeria nodorum	26.83	4.00e-14	72.00
IUUC-Pab-098588	Pongo abelii	85.06	0.00e+00	1020.00
IUUC-Pva-102321	Pteropus vampyrus	95.25	0.00e+00	1184.00
IUUC-Rno-104835	Rattus norvegicus	93.04	0.00e+00	1123.00
IUUC-Sha-107528	Sarcophilus harrisii	92.19	0.00e+00	1142.00
IUUC-Ssc-116161	Sus scrofa	95.76	0.00e+00	1182.00
IUUC-Tgu-116569	Taeniopygia guttata	90.66	0.00e+00	1096.00
IUUC-Tni-120525	Tetraodon nigroviridis	75.80	0.00e+00	881.00
IUUC-Ttr-129297	Tursiops truncatus	95.76	0.00e+00	1187.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence