iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPSIG00000011298.1	ENSPSIT00000012695.1	ENSPSIP00000012634.1
ENSPSIG00000011298.1	ENSPSIT00000012707.1	ENSPSIP00000012646.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	3.60e-12	46.1	37	94

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 3    kekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
            +++ +lyd+ a+ d++L+++kG++++v+  ++q+++W +     ++ +G +P+n+++ ++
   Q: 37   PNLFVALYDFVASGDNTLSITKGEKLRVL-GYNQNGEWSEV--CSKNGQGWVPSNYITPVN 94
           67899************************.*********87..578889*********997 PP

Organism

Pelodiscus sinensis

Protein Sequence
(Fasta)

PEALHRPYGC DVEPQALTEA IRWSSKENLL GATESDPNLF VALYDFVASG DNTLSITKGE 60
KLRVLGYNQN GEWSEVCSKN GQGWVPSNYI TPVNSLEKHS WYHGPVSRSA AEYLLSSLIN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGCTGGGAGC TGGCATGTAA CCTTTACGTT CATGCTTATA GGTAACCATA TAAACAGTTA 60
CTCTGTTACA TCCCTAATCC CGTGTAGTAC TTTACATCTG GAAGATTCAG TGACCCACAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0728--SH3 domain
KW-0808--Transferase
KW-0829--Tyrosine-protein kinase

Interpro

IPR015015--F-actin_binding
IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR000980--SH2
IPR001452--SH3_domain
IPR008266--Tyr_kinase_AS
IPR020635--Tyr_kinase_cat_dom

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00109--PROTEIN_KINASE_TYR
PS50001--SH2
PS50002--SH3

Pfam

PF08919--F_actin_bind
PF07714--Pkinase_Tyr
PF00017--SH2
PF00018--SH3_1

PRINTS

PR00401--SH2DOMAIN
PR00109--TYRKINASE

SMART

SM00808--FABD
SM00252--SH2
SM00326--SH3
SM00219--TyrKc

Gene Ontology

GO:0005623--C:cell
GO:0005524--F:ATP binding
GO:0000287--F:magnesium ion binding
GO:0030145--F:manganese ion binding
GO:0004715--F:non-membrane spanning protein tyrosine kinase activity
GO:0071300--P:cellular response to retinoic acid
GO:0007204--P:positive regulation of cytosolic calcium ion concentration
GO:0010976--P:positive regulation of neuron projection development
GO:0051353--P:positive regulation of oxidoreductase activity
GO:0010863--P:positive regulation of phospholipase C activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002263	Ailuropoda melanoleuca	88.05	0.00e+00	1826.00
IUUC-Apl-003389	Anas platyrhynchos	89.95	0.00e+00	1834.00
IUUC-Ame-010629	Astyanax mexicanus	58.83	0.00e+00	1060.00
IUUC-Bta-013370	Bos taurus	88.69	0.00e+00	1815.00
IUUC-Cja-018894	Callithrix jacchus	88.12	0.00e+00	1829.00
IUUC-Cfa-020398	Canis familiaris	96.43	0.00e+00	1222.00
IUUC-Cpo-022367	Cavia porcellus	83.91	0.00e+00	1707.00
IUUC-Csa-023386	Chlorocebus sabaeus	88.14	0.00e+00	1826.00
IUUC-Cho-024714	Choloepus hoffmanni	91.85	0.00e+00	1365.00
IUUC-Dre-027741	Danio rerio	68.48	0.00e+00	1379.00
IUUC-Dno-029246	Dasypus novemcinctus	88.41	0.00e+00	1830.00
IUUC-Dor-030416	Dipodomys ordii	82.47	0.00e+00	1139.00
IUUC-Ete-032899	Echinops telfairi	67.48	0.00e+00	740.00
IUUC-Eca-033387	Equus caballus	87.97	0.00e+00	1795.00
IUUC-Eeu-035058	Erinaceus europaeus	80.77	0.00e+00	1692.00
IUUC-Fca-036578	Felis catus	82.05	0.00e+00	1642.00
IUUC-Fal-037491	Ficedula albicollis	92.68	0.00e+00	1969.00
IUUC-Gmo-038509	Gadus morhua	72.39	0.00e+00	1184.00
IUUC-Gga-040638	Gallus gallus	92.29	0.00e+00	1924.00
IUUC-Gac-042550	Gasterosteus aculeatus	68.83	0.00e+00	1361.00
IUUC-Ggo-044487	Gorilla gorilla	88.24	0.00e+00	1825.00
IUUC-Hsa-046636	Homo sapiens	88.15	0.00e+00	1825.00
IUUC-Itr-048685	Ictidomys tridecemlineatus	88.24	0.00e+00	1813.00
IUUC-Lch-049530	Latimeria chalumnae	79.73	0.00e+00	1611.00
IUUC-Loc-051933	Lepisosteus oculatus	71.18	0.00e+00	1438.00
IUUC-Laf-053802	Loxodonta africana	87.81	0.00e+00	1858.00
IUUC-Mcc-054836	Macaca mulatta	88.42	0.00e+00	1845.00
IUUC-Mga-059277	Meleagris gallopavo	92.93	0.00e+00	1936.00
IUUC-Mmr-061206	Microcebus murinus	87.52	0.00e+00	1737.00
IUUC-Mdo-062281	Monodelphis domestica	97.56	0.00e+00	1212.00
IUUC-Mmu-063847	Mus musculus	86.82	0.00e+00	1733.00
IUUC-Mpu-066309	Mustela putorius furo	95.79	0.00e+00	1217.00
IUUC-Mlu-068070	Myotis lucifugus	87.96	0.00e+00	1816.00
IUUC-Nle-070062	Nomascus leucogenys	95.95	0.00e+00	1219.00
IUUC-Opr-070534	Ochotona princeps	81.44	0.00e+00	949.00
IUUC-Ont-072440	Oreochromis niloticus	65.83	0.00e+00	1326.00
IUUC-Oan-073526	Ornithorhynchus anatinus	88.89	0.00e+00	1789.00
IUUC-Ocu-074051	Oryctolagus cuniculus	86.62	0.00e+00	1732.00
IUUC-Ola-086752	Oryzias latipes	95.29	0.00e+00	913.00
IUUC-Oga-088767	Otolemur garnettii	82.26	0.00e+00	1630.00
IUUC-Oar-089800	Ovis aries	88.51	0.00e+00	1810.00
IUUC-Ptr-090857	Pan troglodytes	95.95	0.00e+00	1218.00
IUUC-Pan-092279	Papio anubis	88.14	0.00e+00	1822.00
IUUC-Pfo-096543	Poecilia formosa	65.65	0.00e+00	1282.00
IUUC-Pab-097949	Pongo abelii	88.14	0.00e+00	1786.00
IUUC-Pca-100370	Procavia capensis	85.91	0.00e+00	1326.00
IUUC-Pva-103220	Pteropus vampyrus	81.44	0.00e+00	1569.00
IUUC-Rno-105924	Rattus norvegicus	86.34	0.00e+00	1737.00
IUUC-Sha-107114	Sarcophilus harrisii	87.56	0.00e+00	1357.00
IUUC-Smo-109661	Selaginella moellendorffii	29.50	1.00e-22	100.00
IUUC-Sit-110219	Setaria italica	30.03	6.00e-20	92.80
IUUC-Ssc-115968	Sus scrofa	88.33	0.00e+00	1857.00
IUUC-Tgu-117301	Taeniopygia guttata	92.13	0.00e+00	1882.00
IUUC-Tru-118410	Takifugu rubripes	67.94	0.00e+00	1368.00
IUUC-Tni-119991	Tetraodon nigroviridis	67.80	0.00e+00	1364.00
IUUC-Tbe-127362	Tupaia belangeri	85.55	0.00e+00	1684.00
IUUC-Ttr-129291	Tursiops truncatus	88.32	0.00e+00	1820.00
IUUC-Vpa-130800	Vicugna pacos	91.09	0.00e+00	1452.00
IUUC-Xtr-132965	Xenopus tropicalis	76.75	0.00e+00	1274.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence