iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Details
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Basic Information

Integrated Annotations

Tag

Content

iUUCD ID

IUUC-Spo-108246

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Multicopy suppressor of chk1 protein 1

Genbank Nucleotide ID

CU329670

Gene Name

msc1; SPAC343.11c

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
SPAC343.11c	SPAC343.11c.1	SPAC343.11c.1:pep

Annotation

mRNA Expression
GEO
Protein-protein Interaction
iRefIndex	Mentha
Protein Expression/Proteomics

Status

Reviewed

Details

Family	Domain	References (PMIDs)
E3 activity/RING/PHD	PHD	17456468

Classification

Family	E-value	Score	Start	End
E3 activity/RING/PHD	9.70e-28	94.2	1172	1218

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedekslveCekCrewfHpaClklsveeelpnsekwiCpkCr 52
           ++C +C+++++++  ++eCe C+ew+H++C+k+s +++l+ +ek+iCp C+
   Q: 1172 HYC-FCRQPEAGM--MIECELCHEWYHAKCMKMS-KKKLRADEKFICPICD 1218
           69*.*******86..*******************.***************7 PP

Organism

Schizosaccharomyces pombe

Functional Description
(View)

Has a role in regulating chromatin structure via global deacetylation of histone H3. This function is associated with the activity of a histone deacetylase.

Protein Sequence
(Fasta)

MRKNSSHENQ SSENIIEFPY VDFEELNVHS NIFSELEHAK PSTQQQQQQQ NISNETTSTG 60
PRICISRDEF KAVNLLTKEE INVRVTPKKE EFSRGLDFIS DLYDQTARKS GAVRVIPPDN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AAGTTCTGCC ACCACCACTG AATCCTTCAT TATAGAGACA CAATTTTGGG ATTTACCAGG 60
GAGATAAAAT TACCAACGCT GTAAATTGAA TCACCTTGGT AAAGCATGCG GAAAAATTCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR003347--JmjC_dom
IPR003349--JmjN
IPR013637--Lys_sp_deMease-like_dom
IPR019786--Zinc_finger_PHD-type_CS
IPR004198--Znf_C5HC2
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51184--JMJC
PS51183--JMJN
PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF02373--JmjC
PF00628--PHD
PF08429--PLU-1
PF02928--zf-C5HC2

SMART

SM00558--JmjC
SM00545--JmjN
SM00249--PHD

Gene Ontology

GO:0000118--C:histone deacetylase complex
GO:0000790--C:nuclear chromatin
GO:0000812--C:Swr1 complex
GO:0016706--F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
GO:0008270--F:zinc ion binding
GO:0006338--P:chromatin remodeling
GO:0016573--P:histone acetylation
GO:0043486--P:histone exchange

KEGG

spo:SPAC343.11c

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aly-005443	Arabidopsis lyrata	36.07	2.00e-09	53.50
IUUC-Ath-007631	Arabidopsis thaliana	33.96	2.00e-08	50.80
IUUC-Bol-015887	Brassica oleracea	35.85	3.00e-09	53.10
IUUC-Bra-018030	Brassica rapa	35.85	3.00e-09	53.50
IUUC-Cpo-022221	Cavia porcellus	21.25	7.00e-34	137.00
IUUC-Cre-022831	Chlamydomonas reinhardtii	33.33	2.00e-07	49.70
IUUC-Ete-032760	Echinops telfairi	19.93	2.00e-07	50.40
IUUC-Fox-037694	Fusarium oxysporum	26.74	1.00e-104	373.00
IUUC-Hvu-047723	Hordeum vulgare	33.33	5.00e-08	49.30
IUUC-Lma-053234	Leptosphaeria maculans	35.19	2.00e-05	42.70
IUUC-Mac-064463	Musa acuminata	33.82	3.00e-09	53.10
IUUC-Ogl-077260	Oryza glaberrima	31.82	4.00e-09	52.80
IUUC-Oin-079894	Oryza indica	35.19	3.00e-09	53.10
IUUC-Olo-080411	Oryza longistaminata	35.19	2.00e-09	53.50
IUUC-Osa-086057	Oryza sativa	35.19	3.00e-09	53.10
IUUC-Olu-087633	Ostreococcus lucimarinus	34.29	4.00e-09	54.30
IUUC-Ppa-095639	Physcomitrella patens	36.76	4.00e-12	62.80
IUUC-Pop-098853	Populus trichocarpa	31.94	9.00e-08	48.10
IUUC-Pca-100123	Procavia capensis	20.60	8.00e-21	94.70
IUUC-Sja-107734	Schizosaccharomyces japonicus	45.23	0.00e+00	1134.00
IUUC-Smo-109649	Selaginella moellendorffii	44.90	2.00e-10	57.40
IUUC-Stu-112123	Solanum tuberosum	29.59	2.00e-10	57.40

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence