iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Afu-008928

Ensembl Protein ID

CADAFUAP00009687

UniProt Accession

Q4WH28; Q4WH28_ASPFU

Genbank Protein ID

EAL86763.1

Protein Name

Pfs, NACHT and WD domain protein

Genbank Nucleotide ID

AAHF01000009

Gene Name

AFUA_7G07100

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
CADAFUAG00009687	CADAFUAT00009687	CADAFUAP00009687

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	6.10e-94	302.5	1108	1142
UBD/Beta-Prp	6.10e-122	405.4	895	1152

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtg 33
           gH+++v+++af +d  +++s+sdD+ti++WD  +g
   Q: 1108 GHQNWVRAVAFsPDgQTVASASDDKTIRLWDAASG 1142
           8***********99999**************7766 PP

UBD/Beta-Prp

   S: 4    tlkghhksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghe 94
           +l+gh+   +++v+fspd++ +a++s+d+ti++wd+ +g   + l+ghe+ v+av fspdg++ +++s+D+ti++wd  +g   ++lkghe
   Q: 895  VLEGHEN-SVNAVAFSPDGQTVASASDDKTIRLWDAASGAEKQVLKGHENWVNAVAFSPDGQTVASASNDMTIRLWDAASGAEKQVLKGHE 984
           5566665.6667******************************************************************************* PP
   S: 95   dsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvys 185
           +sv +++fsp+g++++s+s+d tir+wd  +g + + +l+gh+++vn v+++pdg+ ++s+s D+t+rlWd ++g   + l+g h++ v+ 
   Q: 985  KSVNAVAFSPDGQTVASASNDMTIRLWDAASGAEKQ-VLKGHEKSVNAVAFSPDGQTVASASFDTTIRLWDAASGAEKQVLEG-HENCVRA 1073
           ************************************.*********************************************9.******* PP
   S: 186  lsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhn 264
           ++f+++g+ ++s+s+d tv lwd  +g   + l+gh+++v+ v+fsp+++ ++s+s+D++ir+Wd  sg   ++l+ h+
   Q: 1074 VAFSPDGQTVASASDDMTVWLWDAASGAEKQVLEGHQNWVRAVAFSPDGQTVASASDDKTIRLWDAASGAEKQVLKAHK 1152
           *************************************************************************999997 PP

Organism

Aspergillus fumigatus

Protein Sequence
(Fasta)

MPTLDPHLYT VAWIAPLEIE VQAARHMLDK VHSGGFPVGP GDDYLFHAGE IHGHNVVIAT 60
FAAGQRYGTN SAASLASHIR KFFPNLWFGL LVGVAAGLPN HSCSPPRDIR LGDVIVAYSP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCCAACCC TCGACCCGCA CCTTTACACC GTCGCATGGA TCGCTCCACT CGAGATCGAG 60
GTACAAGCTG CCAGACATAT GCTGGATAAG GTGCATTCGG GAGGATTTCC TGTCGGCCCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0328--Glycosyltransferase
KW-1185--Reference proteome
KW-0677--Repeat
KW-0808--Transferase
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR007111--NACHT_NTPase
IPR000845--Nucleoside_phosphorylase_d
IPR018391--PQQ_beta_propeller_repeat
IPR011047--Quinoprotein_ADH-like_supfam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50837--NACHT
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00564--PQQ
SM00320--WD40

Gene Ontology

GO:0016757--F:transferase activity, transferring glycosyl groups
GO:0009116--P:nucleoside metabolic process

KEGG

afm:AFUA_7G07100

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ani-009347	Aspergillus nidulans	56.46	0.00e+00	844.00
IUUC-Aor-010043	Aspergillus oryzae	32.68	7.00e-175	606.00
IUUC-Cpo-021524	Cavia porcellus	28.88	2.00e-58	219.00
IUUC-Cre-022868	Chlamydomonas reinhardtii	41.39	2.00e-90	326.00
IUUC-Cin-025447	Ciona intestinalis	35.26	2.00e-62	231.00
IUUC-Ete-032871	Echinops telfairi	41.05	3.00e-47	179.00
IUUC-Eeu-034740	Erinaceus europaeus	38.87	4.00e-55	206.00
IUUC-Fal-037077	Ficedula albicollis	28.21	3.00e-58	219.00
IUUC-Fso-038216	Fusarium solani	41.18	0.00e+00	787.00
IUUC-Ggr-040024	Gaeumannomyces graminis	41.58	0.00e+00	673.00
IUUC-Lch-050200	Latimeria chalumnae	28.54	5.00e-59	221.00
IUUC-Lma-053208	Leptosphaeria maculans	40.08	1.00e-143	502.00
IUUC-Meu-056688	Macropus eugenii	26.91	3.00e-56	212.00
IUUC-Mpo-057480	Magnaporthe poae	37.14	0.00e+00	664.00
IUUC-Mdo-062913	Monodelphis domestica	26.31	1.00e-55	210.00
IUUC-Mlu-067276	Myotis lucifugus	28.54	4.00e-60	225.00
IUUC-Nfi-068459	Neosartorya fischeri	52.09	0.00e+00	1352.00
IUUC-Ont-072191	Oreochromis niloticus	39.14	2.00e-64	237.00
IUUC-Oan-072717	Ornithorhynchus anatinus	27.38	1.00e-56	213.00
IUUC-Psi-093430	Pelodiscus sinensis	28.28	2.00e-60	226.00
IUUC-Pfo-096971	Poecilia formosa	39.14	3.00e-64	237.00
IUUC-Pva-102870	Pteropus vampyrus	27.15	5.00e-58	218.00
IUUC-Ssl-108630	Sclerotinia sclerotiorum	45.25	0.00e+00	627.00
IUUC-Ssc-115654	Sus scrofa	27.35	2.00e-56	213.00
IUUC-Tsy-119007	Tarsius syrichta	27.38	2.00e-55	209.00
IUUC-Tre-122039	Trichoderma reesei	39.57	0.00e+00	717.00
IUUC-Tvi-122636	Trichoderma virens	41.93	0.00e+00	859.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence