iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cfa-020789

Ensembl Protein ID

ENSCAFP00000008036.4

UniProt Accession

E2RHY5; E2RHY5_CANLF

Genbank Protein ID

ENSCAFP00000008036

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAEX03000947

Gene Name

MAP3K10

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCAFG00000005393.4	ENSCAFT00000008670.4	ENSCAFP00000008036.4

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	1.10e-14	54.4	22	77

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 7    qvlydyeaqnddeLtlkkGdvvlvieke...eqdegWlkgvkelegkrGlfPenFve 60
            + +dyea+ d+eLtl++Gd v+v++++   + degW+ g+   +g+ G+fP+n+v+
   Q: 22   TAVFDYEAAGDEELTLRRGDRVQVLSQDcavSGDEGWWTGQ-LPSGRVGVFPSNYVA 77
           589**********************77622257*******7.99***********96 PP

Organism

Canis familiaris

Protein Sequence
(Fasta)

MEEEEGGTAK EWGTTPTGPV WTAVFDYEAA GDEELTLRRG DRVQVLSQDC AVSGDEGWWT 60
GQLPSGRVGV FPSNYVAPGA PAAPAGLQLP QEIPFHELQL EEIIGVGGFG KVYRALWRGE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGAGGAGG AGGAGGGGGG GACGGCCAAG GAGTGGGGCA CGACCCCCAC GGGGCCCGTC 60
TGGACCGCGG TGTTCGACTA CGAGGCGGCG GGCGATGAGG AGCTGACCCT GCGGAGGGGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR011009--Kinase-like_dom
IPR015785--MAP3K10
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR008271--Ser/Thr_kinase_AS
IPR001452--SH3_domain

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST
PS50002--SH3

Pfam

PF00069--Pkinase
PF14604--SH3_9

PRINTS

PR00452--SH3DOMAIN

SMART

SM00220--S_TKc
SM00326--SH3

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005524--F:ATP binding
GO:0004706--F:JUN kinase kinase kinase activity
GO:0003714--F:transcription corepressor activity
GO:0007257--P:activation of JUN kinase activity
GO:0043433--P:negative regulation of sequence-specific DNA binding transcription factor activity
GO:0045892--P:negative regulation of transcription, DNA-templated
GO:0018105--P:peptidyl-serine phosphorylation
GO:0018107--P:peptidyl-threonine phosphorylation
GO:0043065--P:positive regulation of apoptotic process
GO:0007224--P:smoothened signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Cja-019696	Callithrix jacchus	76.87	0.00e+00	1035.00
IUUC-Cpo-021993	Cavia porcellus	75.12	0.00e+00	756.00
IUUC-Csa-024243	Chlorocebus sabaeus	79.10	0.00e+00	1095.00
IUUC-Cho-024961	Choloepus hoffmanni	94.29	8.00e-109	387.00
IUUC-Dno-029095	Dasypus novemcinctus	77.27	0.00e+00	994.00
IUUC-Gma-043854	Glycine max	35.53	3.00e-21	97.10
IUUC-Ggo-045471	Gorilla gorilla	71.88	0.00e+00	702.00
IUUC-Hsa-046936	Homo sapiens	79.35	0.00e+00	1097.00
IUUC-Itr-048231	Ictidomys tridecemlineatus	77.04	0.00e+00	759.00
IUUC-Lpe-050717	Leersia perrieri	31.77	2.00e-20	94.40
IUUC-Mcc-055733	Macaca mulatta	77.37	0.00e+00	1087.00
IUUC-Meu-056131	Macropus eugenii	84.45	8.00e-132	464.00
IUUC-Mmr-061768	Microcebus murinus	96.73	9.00e-147	512.00
IUUC-Mmu-064082	Mus musculus	82.05	0.00e+00	634.00
IUUC-Mpu-065934	Mustela putorius furo	83.88	0.00e+00	1136.00
IUUC-Mlu-068137	Myotis lucifugus	68.01	0.00e+00	1008.00
IUUC-Ocu-074350	Oryctolagus cuniculus	76.36	0.00e+00	963.00
IUUC-Oba-075616	Oryza barthii	35.00	6.00e-21	96.30
IUUC-Obr-076215	Oryza brachyantha	35.03	5.00e-22	99.80
IUUC-Ogl-077159	Oryza glaberrima	35.00	6.00e-21	96.30
IUUC-Ogu-078228	Oryza glumaepatula	35.50	2.00e-21	97.80
IUUC-Oin-079079	Oryza indica	35.05	2.00e-21	98.20
IUUC-Olo-080309	Oryza longistaminata	35.20	2.00e-20	94.40
IUUC-Ome-081104	Oryza meridionalis	35.50	2.00e-21	97.80
IUUC-Oni-082428	Oryza nivara	35.00	7.00e-21	96.30
IUUC-Opu-083527	Oryza punctata	35.50	5.00e-21	96.30
IUUC-Oru-084678	Oryza rufipogon	35.05	2.00e-21	98.20
IUUC-Osa-086117	Oryza sativa	35.05	2.00e-21	98.20
IUUC-Oga-088351	Otolemur garnettii	78.66	0.00e+00	1104.00
IUUC-Ptr-091607	Pan troglodytes	79.45	0.00e+00	1099.00
IUUC-Pan-092403	Papio anubis	77.12	0.00e+00	747.00
IUUC-Pab-098396	Pongo abelii	77.94	0.00e+00	771.00
IUUC-Pop-100071	Populus trichocarpa	32.00	2.00e-19	91.30
IUUC-Ppe-101208	Prunus persica	34.52	2.00e-22	100.00
IUUC-Pva-103086	Pteropus vampyrus	86.26	1.00e-150	527.00
IUUC-Rno-105688	Rattus norvegicus	76.02	0.00e+00	1151.00
IUUC-Sit-110427	Setaria italica	34.67	3.00e-21	97.40
IUUC-Sly-111849	Solanum lycopersicum	35.35	9.00e-21	95.90
IUUC-Stu-112224	Solanum tuberosum	35.35	2.00e-20	94.70
IUUC-Sbi-113963	Sorghum bicolor	34.67	9.00e-22	99.00
IUUC-Tsy-119412	Tarsius syrichta	94.12	3.00e-65	243.00
IUUC-Tca-121565	Theobroma cacao	35.18	3.00e-22	100.00
IUUC-Tbe-127643	Tupaia belangeri	88.34	3.00e-153	535.00
IUUC-Xtr-132108	Xenopus tropicalis	53.17	0.00e+00	764.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence