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Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Hsa-046459
Ensembl Protein ID ENSP00000384269.1
UniProt Accession Q96HL8; A8K8E7; B7WNJ4; B7WPL6; Q8NEL2; Q9H5X4; Q9Y3V5; SH3Y1_HUMAN
Genbank Protein ID BAB15493.1; BAF85001.1; CAG33642.1; CAB43679.2; AAY14957.1; AAH08374.1; AAH08375.1; AAH30778.1; AAH34974.1
Protein Name SH3 domain-containing YSC84-like protein 1
Genbank Nucleotide ID AK026507; AK292312; CR457361; AL050373; AC079779; BC008374; BC008375; BC030778; BC034974
Gene Name SH3YL1
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSG00000035115.21 ENST00000403712.6 ENSP00000384276.1
ENSG00000035115.21 ENST00000626873.2 ENSP00000485824.1
ENSG00000035115.21 ENST00000403657.5 ENSP00000385668.1
ENSG00000035115.21 ENST00000405430.5 ENSP00000384269.1
ENSG00000035115.21 ENST00000479739.6 ENSP00000441266.1
ENSG00000035115.21 ENST00000451005.5 ENSP00000416312.1
ENSG00000035115.21 ENST00000431160.5 ENSP00000399519.1
ENSG00000035115.21 ENST00000481932.1 ENSP00000474411.1
ENSG00000035115.21 ENST00000402632.5 ENSP00000384910.1
Annotation
Cancer Mutation
TCGAICGCCOSMICCGAP
IntOGen
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressTCGAICGC
COSMICTHPAHPM
DNA & RNA Element
UTRdbAREsitecircBasecircRNADb
CircNetmicroRNATRANSFACRepTar
miRcodeRAID2
Protein-protein Interaction
IIDPINAHINTMentha
InWeb_IM
Protein 3D Structure
PDBMMDB
Disease-associated Variation
ClinVarGWASdbGWAS CentralOMIM
Post-translational Modifications (PTMs)
dbPAFPhosphositePlus
DNA Methylation
TCGAICGCCOSMIC
Protein Expression/Proteomics
THPAHPMGPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
UBD/SH3 6.20e-15 56.5 287 340
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   UBD/SH3
   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFve 60
            v +ly++e+q+ ++L++++Gd ++vi+k++   +W++g  +l+g+ G+fP+n+v+
   Q: 287  EVTALYSFEGQQPGDLNFQAGDRITVISKTDSHFDWWEG--KLRGQTGIFPANYVT 340
           689************************************..8************96 PP
   
Organism Homo sapiens
Protein Sequence
(Fasta)
MNNPIPSNLK SEAKKAAKIL REFTEITSRN GPDKIIPAHV IAKAKGLAIL SVIKAGFLVT 60
ARGGSGIVVA RLPDGKWSAP SAIGIAGLGG GFEIGIEVSD LVIILNYDRA VEAFAKGGNL 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Hsa-046459|UBD,SH3|Homo sapiens
Please wait for a moment...
Nucleotide Sequence
(Fasta)
AACCATCCTT AACCAAACTA CTGTTTAATA AACTTATTGA TTTCATCATT CAGCCTTCAA 60
TGAGTCTTAA AAATCAAATG ATGCCCACTA CCAATGTGAA ACAAGGTAAG CCTTCTAATT 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Hsa-046459|UBD,SH3|Homo sapiens
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0002--3D-structure
KW-0025--Alternative splicing
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0728--SH3 domain
Interpro

IPR001452--SH3_domain
IPR033643--SYLF_SH3YL1-like
IPR007461--Ysc84_actin-binding
PROSITE

PS50002--SH3
Pfam

PF00018--SH3_1
PF04366--Ysc84
PRINTS

PR00452--SH3DOMAIN
SMART

SM00326--SH3
Gene Ontology

GO:0032587--C:ruffle membrane
GO:0019902--F:phosphatase binding
GO:0035091--F:phosphatidylinositol binding
GO:0006661--P:phosphatidylinositol biosynthetic process
GO:1900027--P:regulation of ruffle assembly
KEGG hsa:26751
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002343 Ailuropoda melanoleuca 93.86 1.00e-170 592.00
IUUC-Aca-004771 Anolis carolinensis 73.84 2.00e-129 455.00
IUUC-Ago-007765 Ashbya gossypii 52.13 2.00e-49 190.00
IUUC-Acl-008368 Aspergillus clavatus 38.02 3.00e-59 222.00
IUUC-Afl-008637 Aspergillus flavus 38.31 3.00e-60 226.00
IUUC-Afu-008887 Aspergillus fumigatus 39.04 2.00e-56 213.00
IUUC-Ani-009449 Aspergillus nidulans 38.48 6.00e-55 208.00
IUUC-Ang-009628 Aspergillus niger 53.08 2.00e-50 193.00
IUUC-Aor-010189 Aspergillus oryzae 38.77 2.00e-62 233.00
IUUC-Ate-010327 Aspergillus terreus 38.33 3.00e-60 226.00
IUUC-Ame-011024 Astyanax mexicanus 61.67 1.00e-81 296.00
IUUC-Bgr-012270 Blumeria graminis 54.12 2.00e-49 189.00
IUUC-Bta-013425 Bos taurus 89.84 6.00e-116 409.00
IUUC-Bci-013975 Botrytis cinerea 52.61 2.00e-53 203.00
IUUC-Cja-019933 Callithrix jacchus 95.61 2.00e-163 568.00
IUUC-Cfa-021042 Canis familiaris 90.35 2.00e-157 548.00
IUUC-Cpo-021899 Cavia porcellus 90.94 4.00e-177 613.00
IUUC-Cre-022770 Chlamydomonas reinhardtii 32.88 4.00e-12 66.60
IUUC-Csa-023749 Chlorocebus sabaeus 98.83 0.00e+00 627.00
IUUC-Cho-024894 Choloepus hoffmanni 85.63 3.00e-150 524.00
IUUC-Cgl-026405 Colletotrichum gloeosporioides 56.20 3.00e-19 89.70
IUUC-Cne-026909 Cryptococcus neoformans 52.94 9.00e-14 71.60
IUUC-Dre-027389 Danio rerio 65.69 1.00e-111 396.00
IUUC-Dno-029825 Dasypus novemcinctus 92.03 2.00e-128 451.00
IUUC-Dor-030694 Dipodomys ordii 71.26 2.00e-118 419.00
IUUC-Dse-031500 Dothistroma septosporum 54.98 1.00e-56 213.00
IUUC-Ete-032586 Echinops telfairi 87.68 6.00e-152 530.00
IUUC-Eca-033681 Equus caballus 94.15 2.00e-175 608.00
IUUC-Eeu-034867 Erinaceus europaeus 71.55 2.00e-118 418.00
IUUC-Fca-036171 Felis catus 91.33 4.00e-158 550.00
IUUC-Fox-037771 Fusarium oxysporum 53.55 4.00e-49 188.00
IUUC-Fso-038400 Fusarium solani 41.37 1.00e-67 250.00
IUUC-Gmo-038717 Gadus morhua 79.38 9.00e-60 224.00
IUUC-Ggr-040121 Gaeumannomyces graminis 52.61 1.00e-48 187.00
IUUC-Gga-041004 Gallus gallus 75.51 1.00e-125 442.00
IUUC-Gac-041302 Gasterosteus aculeatus 76.34 7.00e-88 317.00
IUUC-Ggo-044549 Gorilla gorilla 99.42 9.00e-172 595.00
IUUC-Itr-048669 Ictidomys tridecemlineatus 90.64 5.00e-162 563.00
IUUC-Kpa-049247 Komagataella pastoris 53.55 7.00e-56 211.00
IUUC-Lch-050422 Latimeria chalumnae 71.85 9.00e-129 452.00
IUUC-Loc-052712 Lepisosteus oculatus 60.56 6.00e-118 417.00
IUUC-Lma-053013 Leptosphaeria maculans 56.00 6.00e-49 188.00
IUUC-Laf-054458 Loxodonta africana 91.52 6.00e-167 580.00
IUUC-Mcc-055578 Macaca mulatta 89.42 1.00e-176 612.00
IUUC-Meu-056108 Macropus eugenii 78.95 9.00e-113 399.00
IUUC-Mor-057225 Magnaporthe oryzae 54.55 4.00e-55 208.00
IUUC-Mpo-057361 Magnaporthe poae 55.77 2.00e-13 68.20
IUUC-Mla-059054 Melampsora laricipopulina 37.68 2.00e-56 213.00
IUUC-Mga-060137 Meleagris gallopavo 75.00 3.00e-127 447.00
IUUC-Mvi-060248 Microbotryum violaceum 47.62 2.00e-51 197.00
IUUC-Mmr-060795 Microcebus murinus 82.11 2.00e-146 511.00
IUUC-Mdo-062948 Monodelphis domestica 85.38 5.00e-161 560.00
IUUC-Mmu-064051 Mus musculus 92.40 2.00e-176 611.00
IUUC-Mpu-066445 Mustela putorius furo 73.10 9.00e-129 452.00
IUUC-Mlu-067480 Myotis lucifugus 79.65 7.00e-135 473.00
IUUC-Nfi-068379 Neosartorya fischeri 39.35 1.00e-59 223.00
IUUC-Ncr-068631 Neurospora crassa 57.82 1.00e-57 216.00
IUUC-Nle-069760 Nomascus leucogenys 97.66 2.00e-179 621.00
IUUC-Opr-071072 Ochotona princeps 96.02 5.00e-73 268.00
IUUC-Ont-072262 Oreochromis niloticus 62.95 5.00e-115 407.00
IUUC-Ocu-074467 Oryctolagus cuniculus 74.93 4.00e-127 448.00
IUUC-Ola-086444 Oryzias latipes 62.25 3.00e-105 374.00
IUUC-Oga-088940 Otolemur garnettii 89.47 3.00e-158 550.00
IUUC-Oar-090295 Ovis aries 89.77 2.00e-151 528.00
IUUC-Ptr-090699 Pan troglodytes 99.59 2.00e-137 481.00
IUUC-Pan-091846 Papio anubis 93.60 5.00e-179 620.00
IUUC-Psi-093789 Pelodiscus sinensis 76.74 3.00e-137 481.00
IUUC-Pno-094914 Phaeosphaeria nodorum 55.45 6.00e-56 211.00
IUUC-Pfo-096809 Poecilia formosa 60.94 1.00e-104 372.00
IUUC-Pab-097579 Pongo abelii 98.83 0.00e+00 627.00
IUUC-Pca-101063 Procavia capensis 89.74 4.00e-168 583.00
IUUC-Ppe-101359 Prunus persica 28.57 5.60e+00 25.40
IUUC-Pva-102694 Pteropus vampyrus 80.41 8.00e-142 496.00
IUUC-Pgr-103300 Puccinia graminis 59.26 5.00e-15 75.90
IUUC-Ptt-103914 Puccinia triticina 62.26 6.00e-15 75.90
IUUC-Pte-104291 Pyrenophora teres 56.19 4.00e-52 199.00
IUUC-Pyt-104786 Pyrenophora triticirepentis 56.70 1.00e-52 200.00
IUUC-Rno-105549 Rattus norvegicus 92.40 3.00e-169 587.00
IUUC-Sce-106404 Saccharomyces cerevisiae 49.78 5.00e-50 191.00
IUUC-Sha-106863 Sarcophilus harrisii 86.80 1.00e-163 569.00
IUUC-Sja-107910 Schizosaccharomyces japonicus 52.13 2.00e-53 203.00
IUUC-Spo-108148 Schizosaccharomyces pombe 50.88 8.00e-56 211.00
IUUC-Ssl-108415 Sclerotinia sclerotiorum 40.59 1.00e-68 253.00
IUUC-Sar-113360 Sorex araneus 97.74 6.00e-59 221.00
IUUC-Sre-115017 Sporisorium reilianum 49.77 6.00e-38 152.00
IUUC-Ssc-115998 Sus scrofa 84.21 5.00e-152 530.00
IUUC-Tgu-116679 Taeniopygia guttata 74.34 2.00e-125 442.00
IUUC-Tru-117723 Takifugu rubripes 61.32 1.00e-97 349.00
IUUC-Tsy-118940 Tarsius syrichta 84.75 5.00e-164 570.00
IUUC-Tni-120501 Tetraodon nigroviridis 63.85 3.00e-100 358.00
IUUC-Tre-121953 Trichoderma reesei 43.49 9.00e-62 230.00
IUUC-Tvi-122297 Trichoderma virens 42.63 2.00e-60 226.00
IUUC-Tme-127198 Tuber melanosporum 54.03 6.00e-57 214.00
IUUC-Tbe-127864 Tupaia belangeri 89.62 4.00e-78 285.00
IUUC-Ttr-128774 Tursiops truncatus 92.98 1.00e-162 565.00
IUUC-Uma-129514 Ustilago maydis 49.30 3.00e-48 186.00
IUUC-Vda-129999 Verticillium dahliae 55.24 2.00e-48 186.00
IUUC-Vpa-130789 Vicugna pacos 90.23 3.00e-123 434.00
IUUC-Xtr-132228 Xenopus tropicalis 66.95 2.00e-117 415.00
IUUC-Xma-134070 Xiphophorus maculatus 62.94 3.00e-108 385.00
IUUC-Yli-134463 Yarrowia lipolytica 51.89 4.00e-55 209.00
Created Date 25-Jun-2017

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