iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mpu-065852

Ensembl Protein ID

ENSMPUP00000011349.1

UniProt Accession

M3YJ42; M3YJ42_MUSPF

Genbank Protein ID

ENSMPUP00000011349

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEYP01025061

Gene Name

HGS

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMPUG00000011441.1	ENSMPUT00000011537.1	ENSMPUP00000011349.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/Alpha-Helix/VHS	4.20e-51	172.4	15	143

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/VHS

   S: 1    atselvtsedwelileicdliqetkegakdalralrkrinnknphvalraLtlLdscvsnCgkkfhvevaskdlleelrellknenepk 89
           ats+l+ ++dwe+il+icdli++ +++ak+a+ +++k++n+knphval+aL++++s+v+nCg+++h+eva+k+++eel+ellk+++e++
   Q: 15   ATSQLLLETDWESILQICDLIRQGDTQAKYAVSSIKKKVNDKNPHVALYALEVMESVVKNCGQTVHDEVANKQTMEELKELLKRQAEVN 103
           799************************************************************************************** PP
   S: 90   vieKlkalivsWadelknepalslivaliktlkeeGlefp 129
           v++K+++li++Wa++++nep++++++++++ +k eG++fp
   Q: 104  VRNKILYLIQAWAHAFRNEPKYKVVQDTYQIMKVEGHVFP 143
           ***************************************8 PP

Organism

Mustela putorius furo

Protein Sequence
(Fasta)

MGRGSGTFER LLDKATSQLL LETDWESILQ ICDLIRQGDT QAKYAVSSIK KKVNDKNPHV 60
ALYALEVMES VVKNCGQTVH DEVANKQTME ELKELLKRQA EVNVRNKILY LIQAWAHAFR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN 60
NNNNNNNNNN NNTCACCAAC AGCGTCTTCC CGACGCCCGA CGGCCCCAGC AGCAGACACA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR008942--ENTH_VHS
IPR024641--HRS_helical
IPR017073--Ubi-bd_Hrs_VPS27
IPR003903--UIM_dom
IPR002014--VHS_dom
IPR000306--Znf_FYVE
IPR017455--Znf_FYVE-rel
IPR011011--Znf_FYVE_PHD
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50330--UIM
PS50179--VHS
PS50178--ZF_FYVE

Pfam

PF01363--FYVE
PF12210--Hrs_helical
PF00790--VHS

SMART

SM00064--FYVE
SM00288--VHS

Gene Ontology

GO:0005829--C:cytosol
GO:0005769--C:early endosome
GO:0070062--C:extracellular exosome
GO:0005764--C:lysosome
GO:0046872--F:metal ion binding
GO:0010324--P:membrane invagination
GO:0046426--P:negative regulation of JAK-STAT cascade
GO:1903543--P:positive regulation of exosomal secretion
GO:0010628--P:positive regulation of gene expression
GO:0072657--P:protein localization to membrane
GO:0006622--P:protein targeting to lysosome
GO:0043405--P:regulation of MAP kinase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001518	Ailuropoda melanoleuca	91.07	0.00e+00	1070.00
IUUC-Apl-003662	Anas platyrhynchos	81.68	0.00e+00	990.00
IUUC-Aca-004940	Anolis carolinensis	82.82	0.00e+00	1163.00
IUUC-Ago-007931	Ashbya gossypii	30.33	6.00e-27	115.00
IUUC-Acl-008274	Aspergillus clavatus	31.41	1.00e-39	158.00
IUUC-Afl-008521	Aspergillus flavus	34.39	7.00e-41	162.00
IUUC-Afu-008774	Aspergillus fumigatus	32.41	2.00e-41	163.00
IUUC-Ani-009445	Aspergillus nidulans	32.96	3.00e-41	163.00
IUUC-Ang-009863	Aspergillus niger	33.21	1.00e-42	167.00
IUUC-Ate-010444	Aspergillus terreus	35.16	3.00e-42	166.00
IUUC-Ame-011111	Astyanax mexicanus	77.46	0.00e+00	932.00
IUUC-Bgr-012087	Blumeria graminis	34.64	2.00e-43	170.00
IUUC-Bta-012506	Bos taurus	91.91	0.00e+00	1186.00
IUUC-Bci-013782	Botrytis cinerea	32.72	9.00e-42	165.00
IUUC-Cel-018493	Caenorhabditis elegans	52.61	2.00e-68	254.00
IUUC-Cja-019998	Callithrix jacchus	86.83	0.00e+00	1077.00
IUUC-Cfa-020615	Canis familiaris	92.97	0.00e+00	1149.00
IUUC-Cpo-022019	Cavia porcellus	89.76	0.00e+00	1204.00
IUUC-Cre-022770	Chlamydomonas reinhardtii	42.65	1.00e-10	61.60
IUUC-Csa-023596	Chlorocebus sabaeus	90.01	0.00e+00	1074.00
IUUC-Cin-025488	Ciona intestinalis	46.32	5.00e-128	451.00
IUUC-Csv-025802	Ciona savignyi	49.26	2.00e-114	406.00
IUUC-Cgl-026560	Colletotrichum gloeosporioides	36.11	7.00e-41	162.00
IUUC-Cne-026847	Cryptococcus neoformans	35.09	5.00e-38	152.00
IUUC-Dre-028353	Danio rerio	77.28	0.00e+00	910.00
IUUC-Dno-029005	Dasypus novemcinctus	85.38	0.00e+00	1115.00
IUUC-Dor-030280	Dipodomys ordii	87.21	0.00e+00	1123.00
IUUC-Dse-031238	Dothistroma septosporum	38.71	5.00e-43	169.00
IUUC-Dme-031952	Drosophila melanogaster	45.61	4.00e-97	348.00
IUUC-Ete-032235	Echinops telfairi	97.27	9.00e-134	470.00
IUUC-Eca-033873	Equus caballus	93.38	0.00e+00	1179.00
IUUC-Eeu-034652	Erinaceus europaeus	96.65	1.00e-105	377.00
IUUC-Fca-036563	Felis catus	93.97	0.00e+00	1196.00
IUUC-Fal-036649	Ficedula albicollis	82.10	0.00e+00	1035.00
IUUC-Fox-037962	Fusarium oxysporum	33.09	3.00e-39	157.00
IUUC-Fso-038396	Fusarium solani	34.43	1.00e-39	158.00
IUUC-Gmo-039510	Gadus morhua	73.35	0.00e+00	939.00
IUUC-Ggr-039938	Gaeumannomyces graminis	33.33	4.00e-39	156.00
IUUC-Gga-040201	Gallus gallus	80.95	0.00e+00	1103.00
IUUC-Gac-041459	Gasterosteus aculeatus	75.65	0.00e+00	946.00
IUUC-Ggo-044573	Gorilla gorilla	91.17	0.00e+00	1165.00
IUUC-Hsa-046009	Homo sapiens	91.17	0.00e+00	1206.00
IUUC-Itr-049065	Ictidomys tridecemlineatus	91.17	0.00e+00	1223.00
IUUC-Kpa-049327	Komagataella pastoris	30.13	2.00e-33	137.00
IUUC-Lch-049944	Latimeria chalumnae	74.61	5.00e-153	533.00
IUUC-Loc-051850	Lepisosteus oculatus	77.87	0.00e+00	1018.00
IUUC-Lma-053252	Leptosphaeria maculans	35.65	1.00e-41	164.00
IUUC-Laf-053346	Loxodonta africana	82.91	0.00e+00	1036.00
IUUC-Mcc-055789	Macaca mulatta	90.04	0.00e+00	1137.00
IUUC-Meu-056329	Macropus eugenii	70.33	7.00e-160	557.00
IUUC-Mor-057205	Magnaporthe oryzae	34.59	1.00e-38	154.00
IUUC-Mpo-057295	Magnaporthe poae	33.76	1.00e-39	158.00
IUUC-Mla-058849	Melampsora laricipopulina	32.90	1.00e-32	135.00
IUUC-Mga-059361	Meleagris gallopavo	80.42	0.00e+00	1033.00
IUUC-Mvi-060561	Microbotryum violaceum	32.18	5.00e-40	159.00
IUUC-Mmr-061122	Microcebus murinus	93.15	0.00e+00	1017.00
IUUC-Mdo-062171	Monodelphis domestica	87.87	0.00e+00	1185.00
IUUC-Mmu-063952	Mus musculus	90.00	0.00e+00	1245.00
IUUC-Mlu-066996	Myotis lucifugus	83.30	2.00e-151	529.00
IUUC-Nfi-068539	Neosartorya fischeri	32.09	1.00e-41	164.00
IUUC-Ncr-068726	Neurospora crassa	39.19	2.00e-40	160.00
IUUC-Nle-070148	Nomascus leucogenys	85.92	0.00e+00	1046.00
IUUC-Opr-070833	Ochotona princeps	71.65	0.00e+00	787.00
IUUC-Ont-071261	Oreochromis niloticus	77.14	0.00e+00	954.00
IUUC-Oan-073684	Ornithorhynchus anatinus	71.11	9.00e-158	549.00
IUUC-Ola-087570	Oryzias latipes	74.34	0.00e+00	963.00
IUUC-Oga-089087	Otolemur garnettii	85.73	0.00e+00	1045.00
IUUC-Oar-089534	Ovis aries	92.18	0.00e+00	1187.00
IUUC-Ptr-091654	Pan troglodytes	85.92	0.00e+00	1056.00
IUUC-Pan-092652	Papio anubis	90.27	0.00e+00	1142.00
IUUC-Pno-095125	Phaeosphaeria nodorum	38.53	4.00e-43	169.00
IUUC-Pfo-096757	Poecilia formosa	76.59	0.00e+00	928.00
IUUC-Pab-097788	Pongo abelii	92.54	0.00e+00	822.00
IUUC-Pca-100145	Procavia capensis	77.18	0.00e+00	893.00
IUUC-Pva-102965	Pteropus vampyrus	85.10	0.00e+00	1109.00
IUUC-Pgr-103609	Puccinia graminis	34.69	1.00e-33	137.00
IUUC-Ptt-103865	Puccinia triticina	35.20	3.00e-34	140.00
IUUC-Pte-104095	Pyrenophora teres	35.40	2.00e-42	167.00
IUUC-Pyt-104668	Pyrenophora triticirepentis	35.87	6.00e-42	166.00
IUUC-Rno-105125	Rattus norvegicus	89.65	0.00e+00	1150.00
IUUC-Sce-106192	Saccharomyces cerevisiae	28.38	5.00e-27	116.00
IUUC-Sha-107066	Sarcophilus harrisii	89.09	0.00e+00	1154.00
IUUC-Sja-107931	Schizosaccharomyces japonicus	32.66	7.00e-43	168.00
IUUC-Spo-108220	Schizosaccharomyces pombe	36.68	3.00e-37	149.00
IUUC-Stu-112464	Solanum tuberosum	45.90	1.00e-13	72.00
IUUC-Sar-113393	Sorex araneus	92.11	5.00e-107	381.00
IUUC-Sre-114986	Sporisorium reilianum	38.57	4.00e-43	169.00
IUUC-Tgu-117505	Taeniopygia guttata	81.77	0.00e+00	1035.00
IUUC-Tru-118494	Takifugu rubripes	76.29	0.00e+00	989.00
IUUC-Tsy-119626	Tarsius syrichta	97.94	2.00e-53	203.00
IUUC-Tni-120174	Tetraodon nigroviridis	72.32	0.00e+00	981.00
IUUC-Tre-122191	Trichoderma reesei	33.82	2.00e-40	160.00
IUUC-Tvi-122318	Trichoderma virens	33.33	3.00e-41	163.00
IUUC-Tme-126914	Tuber melanosporum	34.75	2.00e-44	174.00
IUUC-Ttr-129095	Tursiops truncatus	92.60	0.00e+00	1224.00
IUUC-Uma-129475	Ustilago maydis	37.05	4.00e-40	159.00
IUUC-Vda-129908	Verticillium dahliae	32.87	1.00e-35	144.00
IUUC-Xtr-131900	Xenopus tropicalis	76.95	0.00e+00	1046.00
IUUC-Xma-133124	Xiphophorus maculatus	76.63	0.00e+00	972.00
IUUC-Yli-134682	Yarrowia lipolytica	35.43	3.00e-33	136.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence