iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mdo-062328

UUCD1 version

UUC-MoD-00361

Ensembl Protein ID

ENSMODP00000017856.3

UniProt Accession

F6WKC8; F6WKC8_MONDO

Protein Name

Uncharacterized protein

Gene Name

KLHL22

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000014290.3	ENSMODT00000018185.3	ENSMODP00000017856.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_Other: BTB	3.50e-19	69.1	110	174

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_Other: BTB

   S: 2    DvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgklde 67
           Dv+lvv+g++++ah+i Laas+++F+ +f ++l+e++ +++v i++v++ ++ ++l+F+Yt++l++
   Q: 110  DVVLVVEGKQIEAHRILLAASCDYFRGMFAGGLREME-QEEVLIHGVSYNAMCQILNFIYTSELEL 174
           9***********************************8.*************************986 PP

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

MLVFPASLQP VANMPSPQYR PCLHPSGEIF AFMFSALPTP RNSDEHHWIN RWLVAALFGM 60
AEDQEPPQLG QVPPEPMAQH CNSNTYRSAQ HSQSLLSGLL ALRDSGILFD VVLVVEGKQI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAAGGAATGC AGAGACCCAG AGAAGCCAGC CATGTTAGTC TTTCCAGCCA GTTTGCAGCC 60
AGTGGCAAAT ATGCCCAGCC CACAATACAG GCCATGCCTT CATCCATCTG GAGAGATATT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR030575--KLHL22
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0005813--C:centrosome
GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0005737--C:cytoplasm
GO:0072686--C:mitotic spindle
GO:0005827--C:polar microtubule
GO:0051301--P:cell division
GO:0000070--P:mitotic sister chromatid segregation
GO:0007094--P:mitotic spindle assembly checkpoint
GO:0006513--P:protein monoubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002097	Ailuropoda melanoleuca	82.76	0.00e+00	1084.00
IUUC-Apl-004081	Anas platyrhynchos	78.84	0.00e+00	1046.00
IUUC-Aca-005015	Anolis carolinensis	66.24	0.00e+00	859.00
IUUC-Ame-011712	Astyanax mexicanus	58.27	0.00e+00	730.00
IUUC-Bta-012594	Bos taurus	80.88	0.00e+00	1072.00
IUUC-Cja-019752	Callithrix jacchus	81.93	0.00e+00	885.00
IUUC-Cfa-020884	Canis familiaris	82.76	0.00e+00	1109.00
IUUC-Cpo-021711	Cavia porcellus	82.60	0.00e+00	1105.00
IUUC-Csa-023211	Chlorocebus sabaeus	83.07	0.00e+00	1108.00
IUUC-Dre-028395	Danio rerio	59.42	0.00e+00	757.00
IUUC-Dno-030096	Dasypus novemcinctus	83.23	0.00e+00	1119.00
IUUC-Dor-030709	Dipodomys ordii	81.89	0.00e+00	635.00
IUUC-Eca-033388	Equus caballus	82.45	0.00e+00	1103.00
IUUC-Eeu-034616	Erinaceus europaeus	73.67	0.00e+00	971.00
IUUC-Fca-035815	Felis catus	82.76	0.00e+00	1107.00
IUUC-Fal-037311	Ficedula albicollis	80.00	0.00e+00	1005.00
IUUC-Gmo-039571	Gadus morhua	53.55	7.00e-162	563.00
IUUC-Gga-040992	Gallus gallus	79.00	0.00e+00	1048.00
IUUC-Gac-042041	Gasterosteus aculeatus	57.94	0.00e+00	703.00
IUUC-Ggo-045141	Gorilla gorilla	77.90	0.00e+00	1038.00
IUUC-Hsa-045984	Homo sapiens	83.07	0.00e+00	1109.00
IUUC-Itr-048890	Ictidomys tridecemlineatus	82.60	0.00e+00	1109.00
IUUC-Lch-049700	Latimeria chalumnae	60.28	0.00e+00	753.00
IUUC-Loc-052141	Lepisosteus oculatus	61.44	0.00e+00	813.00
IUUC-Laf-053487	Loxodonta africana	83.04	0.00e+00	1106.00
IUUC-Mcc-054682	Macaca mulatta	83.66	0.00e+00	901.00
IUUC-Meu-055937	Macropus eugenii	86.52	0.00e+00	1129.00
IUUC-Mga-059953	Meleagris gallopavo	79.00	0.00e+00	1048.00
IUUC-Mmr-061743	Microcebus murinus	83.23	0.00e+00	1110.00
IUUC-Mmu-063979	Mus musculus	81.30	0.00e+00	1076.00
IUUC-Mpu-066750	Mustela putorius furo	82.92	0.00e+00	1110.00
IUUC-Mlu-066960	Myotis lucifugus	82.60	0.00e+00	1105.00
IUUC-Nle-069690	Nomascus leucogenys	83.78	0.00e+00	990.00
IUUC-Opr-071059	Ochotona princeps	77.15	0.00e+00	1011.00
IUUC-Ont-072004	Oreochromis niloticus	60.03	0.00e+00	713.00
IUUC-Oan-073172	Ornithorhynchus anatinus	64.90	0.00e+00	757.00
IUUC-Ocu-074310	Oryctolagus cuniculus	81.72	2.00e-131	461.00
IUUC-Ola-086599	Oryzias latipes	57.10	0.00e+00	718.00
IUUC-Oga-087980	Otolemur garnettii	82.76	0.00e+00	1107.00
IUUC-Oar-089956	Ovis aries	67.75	0.00e+00	793.00
IUUC-Ptr-090598	Pan troglodytes	83.66	0.00e+00	993.00
IUUC-Pan-092387	Papio anubis	83.46	0.00e+00	902.00
IUUC-Psi-093484	Pelodiscus sinensis	79.15	0.00e+00	1063.00
IUUC-Pma-094224	Petromyzon marinus	50.50	5.00e-176	610.00
IUUC-Pfo-096149	Poecilia formosa	56.30	0.00e+00	717.00
IUUC-Pab-098097	Pongo abelii	83.23	0.00e+00	1110.00
IUUC-Pca-100118	Procavia capensis	82.70	0.00e+00	635.00
IUUC-Pva-103174	Pteropus vampyrus	82.40	2.00e-133	469.00
IUUC-Rno-105350	Rattus norvegicus	80.97	0.00e+00	1059.00
IUUC-Sha-106817	Sarcophilus harrisii	96.63	8.00e-159	553.00
IUUC-Sar-113490	Sorex araneus	85.13	1.00e-173	602.00
IUUC-Ssc-115827	Sus scrofa	82.60	0.00e+00	1097.00
IUUC-Tgu-116748	Taeniopygia guttata	81.75	0.00e+00	903.00
IUUC-Tru-118644	Takifugu rubripes	56.93	0.00e+00	709.00
IUUC-Tsy-118888	Tarsius syrichta	77.40	0.00e+00	898.00
IUUC-Tni-120060	Tetraodon nigroviridis	55.57	5.00e-176	610.00
IUUC-Ttr-129183	Tursiops truncatus	82.56	0.00e+00	973.00
IUUC-Xtr-132780	Xenopus tropicalis	68.99	0.00e+00	917.00
IUUC-Xma-133062	Xiphophorus maculatus	55.31	0.00e+00	718.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence