iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress	GXD
DNA & RNA Element
AREsite	microRNA	TRANSFAC	RepTar
RAID2
Protein-protein Interaction
HINT
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box	3.50e-13	50.3	184	228

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box

   S: 4    lwllrseprSLqhLCRlaIrrclgsqrlkaidkLPLPksLkdYLlyedy 52
           lw ++s++ SLq+LC++a+++c++ + +   dkLPLP +L+++L+++++
   Q: 184  LW-RPSKVLSLQELCCRAVVSCTPGHLV---DKLPLPVALRSHLKSFSM 228
           67.99********************888...***************976 PP

Organism

Mus musculus

Protein Sequence
(Fasta)

MMSSLGSPVR AYDFLLKFLL VGDSDVGKGE ILASLQDGAA ESPYGHPAGI DHKTTTILLD 60
GRRVKLQLWD TSGQGRFCTI FRSYSRGAQG VVLVYDIANR WSFDGINRWI KEIDEHAPGV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TGTCAAGCTC CCCCGACCGG TGGAGCGTTC GAGGGGCCCG CGGCGCTCGG GGACCCTCCG 60
CCGCCTGCGC GCAGCCTTGG GCCGGTATGG GCGGGGTGGC TGGGCCGGCA TGATGAGCTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR027417--P-loop_NTPase
IPR005225--Small_GTP-bd_dom
IPR001806--Small_GTPase
IPR001496--SOCS_box

PROSITE

PS50225--SOCS

Pfam

PF00071--Ras
PF07525--SOCS_box

SMART

SM00253--SOCS
SM00969--SOCS_box

Gene Ontology

GO:0005622--C:intracellular
GO:0005525--F:GTP binding
GO:0016567--P:protein ubiquitination
GO:0007264--P:small GTPase mediated signal transduction

KEGG

mmu:217371

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Apl-003206	Anas platyrhynchos	88.41	1.00e-126	445.00
IUUC-Aca-005004	Anolis carolinensis	86.99	1.00e-135	475.00
IUUC-Ame-011456	Astyanax mexicanus	83.81	5.00e-142	496.00
IUUC-Bta-012683	Bos taurus	88.13	1.00e-147	514.00
IUUC-Cja-018870	Callithrix jacchus	84.17	4.00e-139	486.00
IUUC-Cfa-020527	Canis familiaris	90.48	3.00e-114	404.00
IUUC-Cpo-021644	Cavia porcellus	92.91	1.00e-148	518.00
IUUC-Csa-023150	Chlorocebus sabaeus	93.17	1.00e-157	548.00
IUUC-Cho-024716	Choloepus hoffmanni	90.24	2.00e-86	310.00
IUUC-Dre-028614	Danio rerio	83.15	7.00e-140	489.00
IUUC-Eca-033492	Equus caballus	91.81	2.00e-129	454.00
IUUC-Fca-035705	Felis catus	90.48	9.00e-127	445.00
IUUC-Gga-040925	Gallus gallus	87.41	3.00e-148	517.00
IUUC-Ggo-045012	Gorilla gorilla	83.45	1.00e-138	485.00
IUUC-Hsa-046747	Homo sapiens	92.81	1.00e-156	545.00
IUUC-Loc-052325	Lepisosteus oculatus	85.66	7.00e-146	509.00
IUUC-Laf-053340	Loxodonta africana	89.57	4.00e-149	520.00
IUUC-Mcc-054711	Macaca mulatta	90.75	2.00e-153	534.00
IUUC-Mga-059204	Meleagris gallopavo	87.41	7.00e-148	516.00
IUUC-Mpu-066352	Mustela putorius furo	89.66	6.00e-126	442.00
IUUC-Nle-070096	Nomascus leucogenys	92.09	4.00e-155	540.00
IUUC-Opr-070662	Ochotona princeps	88.85	3.00e-147	513.00
IUUC-Ont-072397	Oreochromis niloticus	81.75	4.00e-137	480.00
IUUC-Ocu-074559	Oryctolagus cuniculus	90.65	2.00e-143	501.00
IUUC-Olo-080270	Oryza longistaminata	36.36	4.00e-12	65.90
IUUC-Oga-088133	Otolemur garnettii	92.09	2.00e-155	541.00
IUUC-Oar-089702	Ovis aries	86.09	2.00e-119	421.00
IUUC-Ptr-090544	Pan troglodytes	93.10	3.00e-146	511.00
IUUC-Pan-092812	Papio anubis	93.17	1.00e-157	548.00
IUUC-Psi-093120	Pelodiscus sinensis	87.77	4.00e-150	523.00
IUUC-Pab-098735	Pongo abelii	93.17	1.00e-157	548.00
IUUC-Pva-102361	Pteropus vampyrus	90.80	1.00e-136	478.00
IUUC-Rno-105063	Rattus norvegicus	98.57	5.00e-165	573.00
IUUC-Sar-113518	Sorex araneus	85.16	4.00e-127	447.00
IUUC-Ssc-115719	Sus scrofa	89.55	9.00e-142	495.00
IUUC-Tsy-119011	Tarsius syrichta	89.47	8.00e-103	365.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence