iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Bta-012514

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

DAAA02045436

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSBTAG00000008762.5	ENSBTAT00000011545.5	ENSBTAP00000011545.5

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	8.60e-81	272.0	795	1155

Active Site

Position(s)	Description	Evidence
1129	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 4    dlkkrlevefvgEegldlgGvtreflallskelqnpdlglf.......lysendketlqpnpdsglknpehlklFeflGrllgkalq 83
           d ++ ++++f+gEe+++++G++r+fl+++++elq+++l+l+       ++++++k+ l+p+p ++     +++l +flG+llg+a++
   Q: 795  DPTYAFNIRFTGEEVHGTSGSFRHFLWQVCRELQSSSLSLLllcpssaVNKNKGKYILTPSPITY----GEEQLLHFLGQLLGIAIR 877
           5667789*********************************9999999888888***********9....789*************** PP
   S: 84   dgrlldlplsksfyklllgkklsl.edleevdpelyks.lkeikenaesdieelgldltfs..vseei...............lget 151
            + +l+l+l +sf+k+l+g++l+  +dl+e d  +y++ +k+ + n+e+++e+l+++++++  +  ++                 + 
   Q: 878  ADVPLPLDLLPSFWKTLVGEPLDPdQDLQEADVLTYNYvKKFESINDETELEALCAEIASQhlA--TEspegpnkpccrftylTMTG 962
           **************************************56666677799999999999999532..334699*********655555 PP
   S: 152  keeeLkpgGenipVtneNkeeYvklvveyrlke.gikeqveafreGfneviplellslFteeelellicGeeeidvedlkketkykg 237
           +e+eL+++G++ipV++eNk+ Y  ++ ++rl+e +  e+v+a+r+G+  +ipl+ll+++++ e+el +cG ++i++e lk++t+y+ 
   Q: 963  EEVELCSRGRHIPVAWENKDIYAAAIRSLRLRElQNVECVTAVRAGLGAIIPLQLLTMLSPLEMELRTCGLPYINLEFLKAHTMYQV 1049
           6667*****************************9***************************************************** PP
   S: 238  gytedspaiqwFwevleefsseerkafLqFvTgssrlPl......gGfaelk....prlfvirk...dasddrlPssnTCfnyLkLP 311
           g++e++++i++Fw +le+f +ee ++f++F+++++r+P+      gG ++ +    p+++  ++    + d+r+++++TC++++kLP
   Q: 1050 GLMETDQHIEFFWGALEMFAQEELCKFIKFACNQERIPFtcpckdGGPDTAHvppyPMKIAPPDgtaGSPDSRYIRVETCMFMIKLP 1136
           *********************************************99999999988888888889955555**************** PP
   S: 312  eYsskeilkekLlyAieet 330
           +Yss ei+ ekL++Ai+++
   Q: 1137 QYSSLEIMLEKLRCAIHYR 1155
           ****************986 PP

Organism

Bos taurus

Protein Sequence
(Fasta)

MEGCLAVAEV TLPTNMSVTA SGVTSATAPN LSDSSSSSSS SPGQTPQSPS LLSKRKKVKM 60
KREKASSSGK RQSSRSVDSD PAVLSIGGSK PEDMLWFHRA LTLLIILRHL TRKDPQGLGV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGAGGGCT GCCTGGCGGT GGCCGAGGTG ACCCTGCCCA CCAACATGAG TGTCACCGCC 60
AGCGGGGTGA CGTCAGCAAC TGCCCCAAAC CTCAGCGACT CGTCCTCCTC CTCATCGTCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000569--HECT_dom

PROSITE

PS50237--HECT

Pfam

PF00632--HECT

SMART

SM00119--HECTc

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002256	Ailuropoda melanoleuca	97.33	0.00e+00	1900.00
IUUC-Apl-004161	Anas platyrhynchos	90.35	0.00e+00	1820.00
IUUC-Aca-005341	Anolis carolinensis	87.04	0.00e+00	1747.00
IUUC-Ame-011574	Astyanax mexicanus	76.88	0.00e+00	1610.00
IUUC-Cja-019148	Callithrix jacchus	96.90	0.00e+00	1947.00
IUUC-Cfa-020499	Canis familiaris	97.85	0.00e+00	1886.00
IUUC-Cpo-021894	Cavia porcellus	93.64	0.00e+00	1922.00
IUUC-Csa-023079	Chlorocebus sabaeus	97.24	0.00e+00	1958.00
IUUC-Cho-024415	Choloepus hoffmanni	89.15	0.00e+00	677.00
IUUC-Dre-027452	Danio rerio	74.84	0.00e+00	1443.00
IUUC-Dno-029595	Dasypus novemcinctus	96.13	0.00e+00	1939.00
IUUC-Dor-030849	Dipodomys ordii	88.93	0.00e+00	1515.00
IUUC-Ete-032563	Echinops telfairi	90.64	0.00e+00	1189.00
IUUC-Eca-034202	Equus caballus	97.42	0.00e+00	1838.00
IUUC-Eeu-035175	Erinaceus europaeus	98.01	0.00e+00	1087.00
IUUC-Fca-036295	Felis catus	97.33	0.00e+00	1936.00
IUUC-Fal-037003	Ficedula albicollis	88.23	0.00e+00	1014.00
IUUC-Gmo-038579	Gadus morhua	82.04	0.00e+00	1124.00
IUUC-Gga-040961	Gallus gallus	90.18	0.00e+00	1813.00
IUUC-Gac-041899	Gasterosteus aculeatus	84.72	0.00e+00	1154.00
IUUC-Ggo-045099	Gorilla gorilla	97.24	0.00e+00	2020.00
IUUC-Hsa-046331	Homo sapiens	97.50	0.00e+00	2001.00
IUUC-Itr-048190	Ictidomys tridecemlineatus	97.16	0.00e+00	1913.00
IUUC-Lch-050062	Latimeria chalumnae	80.16	2.00e-159	554.00
IUUC-Loc-052630	Lepisosteus oculatus	76.56	0.00e+00	1430.00
IUUC-Laf-053394	Loxodonta africana	96.12	0.00e+00	1974.00
IUUC-Mcc-055763	Macaca mulatta	97.33	0.00e+00	1958.00
IUUC-Meu-056039	Macropus eugenii	86.30	0.00e+00	1712.00
IUUC-Mga-059500	Meleagris gallopavo	89.59	0.00e+00	1799.00
IUUC-Mmr-060868	Microcebus murinus	95.00	0.00e+00	1926.00
IUUC-Mdo-062772	Monodelphis domestica	92.25	0.00e+00	1868.00
IUUC-Mmu-063606	Mus musculus	94.92	0.00e+00	1881.00
IUUC-Mpu-065860	Mustela putorius furo	97.76	0.00e+00	1913.00
IUUC-Mlu-067376	Myotis lucifugus	97.20	0.00e+00	1837.00
IUUC-Nle-069693	Nomascus leucogenys	96.81	0.00e+00	1993.00
IUUC-Ont-072470	Oreochromis niloticus	79.44	0.00e+00	1671.00
IUUC-Oan-073693	Ornithorhynchus anatinus	88.24	0.00e+00	1846.00
IUUC-Ocu-074032	Oryctolagus cuniculus	94.40	0.00e+00	1930.00
IUUC-Oga-088546	Otolemur garnettii	96.90	0.00e+00	1919.00
IUUC-Oar-089643	Ovis aries	93.12	0.00e+00	771.00
IUUC-Ptr-090504	Pan troglodytes	97.50	0.00e+00	1999.00
IUUC-Pan-092543	Papio anubis	97.33	0.00e+00	1960.00
IUUC-Psi-093952	Pelodiscus sinensis	85.11	0.00e+00	1822.00
IUUC-Pfo-096356	Poecilia formosa	79.11	0.00e+00	1674.00
IUUC-Pab-098240	Pongo abelii	97.59	0.00e+00	1962.00
IUUC-Pca-100994	Procavia capensis	95.20	0.00e+00	1203.00
IUUC-Pva-102263	Pteropus vampyrus	96.73	0.00e+00	1895.00
IUUC-Rno-104888	Rattus norvegicus	94.32	0.00e+00	1877.00
IUUC-Sha-106944	Sarcophilus harrisii	90.18	0.00e+00	1864.00
IUUC-Sar-113556	Sorex araneus	86.62	0.00e+00	967.00
IUUC-Ssc-116187	Sus scrofa	98.36	0.00e+00	1937.00
IUUC-Tgu-116655	Taeniopygia guttata	89.85	0.00e+00	1764.00
IUUC-Tru-118093	Takifugu rubripes	76.21	0.00e+00	1362.00
IUUC-Tni-119665	Tetraodon nigroviridis	71.09	6.00e-138	483.00
IUUC-Tbe-127962	Tupaia belangeri	94.40	0.00e+00	787.00
IUUC-Ttr-128819	Tursiops truncatus	92.08	0.00e+00	1798.00
IUUC-Vpa-130482	Vicugna pacos	98.39	2.00e-66	249.00
IUUC-Xtr-132222	Xenopus tropicalis	81.50	0.00e+00	1835.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence