iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Aca-004768

Ensembl Protein ID

ENSACAP00000012866.3

UniProt Accession

H9GJL5; H9GJL5_ANOCA

Protein Name

Uncharacterized protein

Gene Name

MAP3K10

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSACAG00000013081.3	ENSACAT00000013123.3	ENSACAP00000012866.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	2.60e-15	56.1	28	81

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 8    vlydyeaqnddeLtlkkGdvvlvi...ekeeqdegWlkgvkelegkrGlfPenFve 60
           + +dyea+ ++eLtl++Gd v+v+   +  + degW+ g  +l+ k G+fP+n+v+
   Q: 28   AVFDYEATAEEELTLRRGDRVEVLskdSTVSGDEGWWTG--KLQDKVGIFPSNYVT 81
           89**********************66666678*******..8************97 PP

Organism

Anolis carolinensis

Protein Sequence
(Fasta)

MEPACKETQD SIGAWNTGPM TPNPVWMAVF DYEATAEEEL TLRRGDRVEV LSKDSTVSGD 60
EGWWTGKLQD KVGIFPSNYV TSNHKYTQIQ GSLTCPPPLE ISFQELELDE IIGVGGFGKV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTGCCTGCCA GGCGCGCCTC CCTCCTCCTC CTGCCCAGCC GGGCACCAGC TGACAGGTCC 60
TCCCGCGACG GCTGCAAGGG AGGGATTGCG GGGAAGGAGG GACCCCCGGA GCCTTGCCAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR011009--Kinase-like_dom
IPR015785--MAP3K10
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR008271--Ser/Thr_kinase_AS
IPR001452--SH3_domain

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST
PS50002--SH3

Pfam

PF07714--Pkinase_Tyr
PF14604--SH3_9

PRINTS

PR00452--SH3DOMAIN
PR00109--TYRKINASE

SMART

SM00220--S_TKc
SM00326--SH3

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005524--F:ATP binding
GO:0004706--F:JUN kinase kinase kinase activity
GO:0003714--F:transcription corepressor activity
GO:0007257--P:activation of JUN kinase activity
GO:0043433--P:negative regulation of sequence-specific DNA binding transcription factor activity
GO:0045892--P:negative regulation of transcription, DNA-templated
GO:0018105--P:peptidyl-serine phosphorylation
GO:0018107--P:peptidyl-threonine phosphorylation
GO:0043065--P:positive regulation of apoptotic process
GO:0007224--P:smoothened signaling pathway

KEGG

acs:100565973

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001187	Ailuropoda melanoleuca	76.08	0.00e+00	804.00
IUUC-Bdi-014195	Brachypodium distachyon	32.87	1.00e-22	101.00
IUUC-Cja-019696	Callithrix jacchus	77.06	0.00e+00	777.00
IUUC-Cpo-021993	Cavia porcellus	78.41	0.00e+00	802.00
IUUC-Csa-024243	Chlorocebus sabaeus	76.12	0.00e+00	768.00
IUUC-Cho-024961	Choloepus hoffmanni	70.18	5.00e-85	308.00
IUUC-Dre-028573	Danio rerio	75.46	0.00e+00	829.00
IUUC-Dno-029095	Dasypus novemcinctus	74.49	0.00e+00	760.00
IUUC-Dor-030866	Dipodomys ordii	64.20	5.00e-180	624.00
IUUC-Dme-032210	Drosophila melanogaster	50.26	9.00e-144	504.00
IUUC-Eca-033782	Equus caballus	73.65	1.00e-122	434.00
IUUC-Fca-036250	Felis catus	75.31	0.00e+00	789.00
IUUC-Gmo-038497	Gadus morhua	75.86	0.00e+00	812.00
IUUC-Gac-042509	Gasterosteus aculeatus	71.49	0.00e+00	824.00
IUUC-Ggo-045471	Gorilla gorilla	73.14	0.00e+00	727.00
IUUC-Hsa-046936	Homo sapiens	76.95	0.00e+00	764.00
IUUC-Itr-048231	Ictidomys tridecemlineatus	77.72	0.00e+00	786.00
IUUC-Loc-052286	Lepisosteus oculatus	75.54	0.00e+00	857.00
IUUC-Mcc-055733	Macaca mulatta	73.69	0.00e+00	763.00
IUUC-Meu-056762	Macropus eugenii	70.65	1.00e-168	586.00
IUUC-Mdo-062516	Monodelphis domestica	69.93	0.00e+00	854.00
IUUC-Mmu-064082	Mus musculus	65.32	0.00e+00	908.00
IUUC-Mpu-065934	Mustela putorius furo	76.95	0.00e+00	795.00
IUUC-Mlu-068137	Myotis lucifugus	65.55	0.00e+00	845.00
IUUC-Opr-070869	Ochotona princeps	76.24	5.00e-162	565.00
IUUC-Ont-072492	Oreochromis niloticus	70.74	0.00e+00	854.00
IUUC-Ocu-074350	Oryctolagus cuniculus	75.45	0.00e+00	771.00
IUUC-Oba-075594	Oryza barthii	34.88	2.00e-22	100.00
IUUC-Obr-076837	Oryza brachyantha	35.38	1.00e-24	107.00
IUUC-Ogl-077631	Oryza glaberrima	34.88	2.00e-22	101.00
IUUC-Ogu-078578	Oryza glumaepatula	34.88	2.00e-22	101.00
IUUC-Oin-079434	Oryza indica	34.88	2.00e-22	100.00
IUUC-Olo-080520	Oryza longistaminata	34.88	1.00e-22	101.00
IUUC-Oni-082833	Oryza nivara	34.88	2.00e-22	100.00
IUUC-Oru-084926	Oryza rufipogon	34.88	2.00e-22	101.00
IUUC-Osa-086179	Oryza sativa	34.88	2.00e-22	100.00
IUUC-Ola-087224	Oryzias latipes	70.16	0.00e+00	847.00
IUUC-Oga-088351	Otolemur garnettii	76.82	0.00e+00	821.00
IUUC-Oar-089467	Ovis aries	64.74	0.00e+00	632.00
IUUC-Ptr-091607	Pan troglodytes	76.95	0.00e+00	764.00
IUUC-Pan-092403	Papio anubis	75.84	0.00e+00	759.00
IUUC-Psi-093760	Pelodiscus sinensis	64.44	0.00e+00	678.00
IUUC-Pfo-096104	Poecilia formosa	69.05	0.00e+00	834.00
IUUC-Pab-098396	Pongo abelii	76.95	0.00e+00	763.00
IUUC-Rno-105688	Rattus norvegicus	65.29	0.00e+00	919.00
IUUC-Sha-107470	Sarcophilus harrisii	56.51	3.00e-168	585.00
IUUC-Smo-109331	Selaginella moellendorffii	28.92	1.00e-25	110.00
IUUC-Sit-110451	Setaria italica	32.14	4.00e-23	103.00
IUUC-Ssc-115332	Sus scrofa	76.92	0.00e+00	795.00
IUUC-Tru-117692	Takifugu rubripes	68.73	0.00e+00	855.00
IUUC-Tsy-119412	Tarsius syrichta	87.96	8.00e-53	201.00
IUUC-Tni-120689	Tetraodon nigroviridis	67.60	0.00e+00	827.00
IUUC-Ttr-128550	Tursiops truncatus	75.28	0.00e+00	822.00
IUUC-Xtr-132108	Xenopus tropicalis	65.37	0.00e+00	1041.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence