iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Basic Information

Integrated Annotations

Tag

Content

UUCD2 ID

IUUC-Ath-006581

UUCD1 version

UUC-ArT-00651

Ensembl Protein ID

AT2G19410.2

UniProt Accession

Q8S8S7; PUB34_ARATH

Genbank Protein ID

AAM14871.1; AEC06878.1

Protein Name

U-box domain-containing protein 34; Plant U-box protein 34; E3 ubiquitin ligase; RING-type E3 ubiquitin transferase; Serine/threonine-protein kinase

Genbank Nucleotide ID

AC003058; CP002685

Gene Name

PUB34; At2g19410; F27F23.21

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
AT2G19410	AT2G19410.3	AT2G19410.3
AT2G19410	AT2G19410.1	AT2G19410.1
AT2G19410	AT2G19410.2	AT2G19410.2

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
Post-translational Modifications (PTMs)
dbPPT
Protein Expression/Proteomics

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/U-box	7.50e-22	78.1	746	815

Active Site

Position(s)	Description	Evidence
564	Proton acceptor	ECO:0000255\|PROSITE-ProRule:PRU00159, ECO:0000255\|PROSITE-ProRule:PRU10027}

Domain Profile

E3 activity/RING/U-box

   S: 2    vpeeflCpIslelMrdPvvlpsGitydrssIekwlasggktcPvtrqplteedlvPnltlrrliqawceen 72
            p+++ CpI  e+M++P ++++G ty+r++I  wl++ +  +Pvtrq+l++ +l+Pn+tlr+ i +w ++ 
   Q: 746  APSHYFCPILREIMEEPEIAADGFTYERKAILAWLEKHNI-SPVTRQKLDHFKLTPNHTLRSAIRDWKSRV 815
           6999*******************************99999.**************************9886 PP

Organism

Arabidopsis thaliana

Functional Description
(View)

Functions as an E3 ubiquitin ligase.

Protein Sequence
(Fasta)

MVVMLTQEMS GGGGPKAEEG QLFVAVAVKG LIGDKLGGAG SRRAVRWAVD NLLPKADKFV 60
MIHVIPTITS IPTPTGDRLP VEEVEESVVE MYVRDVKKEY ETVFVPFLKM CKSTRSTKCK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGTGGTGA TGCTGACGCA AGAAATGAGT GGCGGTGGTG GTCCAAAGGC GGAAGAGGGT 60
CAGCTGTTTG TGGCGGTGGC CGTGAAGGGT TTGATCGGAG ACAAATTAGG CGGTGCAGGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0723--Serine/threonine-protein kinase
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR014729--Rossmann-like_a/b/a_fold
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR008271--Ser/Thr_kinase_AS
IPR003613--Ubox_domain
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST
PS51698--U_BOX

Pfam

PF07714--Pkinase_Tyr
PF04564--U-box

SMART

SM00220--S_TKc
SM00504--Ubox

Gene Ontology

GO:0005524--F:ATP binding
GO:0004674--F:protein serine/threonine kinase activity
GO:0004842--F:ubiquitin-protein transferase activity

KEGG

ath:AT2G19410

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001187	Ailuropoda melanoleuca	32.38	6.00e-28	119.00
IUUC-Aca-004389	Anolis carolinensis	29.61	2.00e-19	91.30
IUUC-Aly-006459	Arabidopsis lyrata	88.18	0.00e+00	1434.00
IUUC-Ame-011785	Astyanax mexicanus	29.51	2.00e-24	106.00
IUUC-Bta-013545	Bos taurus	32.38	8.00e-28	118.00
IUUC-Bol-015378	Brassica oleracea	85.71	0.00e+00	1354.00
IUUC-Bra-017021	Brassica rapa	85.40	0.00e+00	1357.00
IUUC-Cja-019696	Callithrix jacchus	33.45	2.00e-29	123.00
IUUC-Cfa-020080	Canis familiaris	29.89	4.00e-23	102.00
IUUC-Cpo-021993	Cavia porcellus	33.10	8.00e-29	122.00
IUUC-Csa-024243	Chlorocebus sabaeus	33.10	7.00e-29	122.00
IUUC-Csv-026102	Ciona savignyi	30.80	6.00e-26	111.00
IUUC-Dre-027645	Danio rerio	31.36	3.00e-24	106.00
IUUC-Dno-029095	Dasypus novemcinctus	33.45	6.00e-30	125.00
IUUC-Dme-032210	Drosophila melanogaster	27.78	2.00e-20	94.40
IUUC-Eca-033782	Equus caballus	31.48	1.00e-22	101.00
IUUC-Fca-036250	Felis catus	32.38	2.00e-28	120.00
IUUC-Gmo-039264	Gadus morhua	31.65	2.00e-24	107.00
IUUC-Ggo-045471	Gorilla gorilla	33.10	4.00e-29	122.00
IUUC-Hsa-046936	Homo sapiens	33.10	4.00e-29	122.00
IUUC-Itr-048231	Ictidomys tridecemlineatus	33.10	2.00e-29	123.00
IUUC-Loc-052411	Lepisosteus oculatus	29.05	2.00e-25	110.00
IUUC-Laf-053926	Loxodonta africana	30.56	1.00e-22	101.00
IUUC-Mcc-055733	Macaca mulatta	33.10	7.00e-29	122.00
IUUC-Mga-059270	Meleagris gallopavo	26.07	9.00e-17	82.00
IUUC-Mmr-061210	Microcebus murinus	30.56	1.00e-22	102.00
IUUC-Mdo-062516	Monodelphis domestica	32.03	3.00e-28	120.00
IUUC-Mmu-064082	Mus musculus	32.74	9.00e-29	121.00
IUUC-Mpu-065934	Mustela putorius furo	32.74	1.00e-28	121.00
IUUC-Mlu-068137	Myotis lucifugus	32.74	2.00e-26	114.00
IUUC-Nle-068969	Nomascus leucogenys	30.56	2.00e-22	101.00
IUUC-Opr-070869	Ochotona princeps	30.91	2.00e-20	94.40
IUUC-Ont-071274	Oreochromis niloticus	30.00	2.00e-25	110.00
IUUC-Oan-073100	Ornithorhynchus anatinus	26.07	8.00e-17	82.40
IUUC-Ocu-074350	Oryctolagus cuniculus	32.74	2.00e-28	120.00
IUUC-Ola-086581	Oryzias latipes	29.29	2.00e-25	110.00
IUUC-Oga-088351	Otolemur garnettii	32.74	4.00e-29	123.00
IUUC-Oar-089467	Ovis aries	29.52	6.00e-23	102.00
IUUC-Ptr-091607	Pan troglodytes	33.10	4.00e-29	122.00
IUUC-Pan-092403	Papio anubis	33.10	5.00e-29	122.00
IUUC-Psi-093760	Pelodiscus sinensis	31.36	5.00e-24	105.00
IUUC-Pma-094398	Petromyzon marinus	30.58	5.00e-19	89.70
IUUC-Pab-098396	Pongo abelii	33.10	5.00e-29	122.00
IUUC-Pca-100945	Procavia capensis	30.35	4.00e-18	86.70
IUUC-Rno-105688	Rattus norvegicus	32.74	1.00e-28	121.00
IUUC-Ssc-115332	Sus scrofa	32.38	3.00e-28	119.00
IUUC-Tsy-119216	Tarsius syrichta	26.07	1.00e-16	80.90
IUUC-Tbe-127643	Tupaia belangeri	32.72	5.00e-28	118.00
IUUC-Ttr-128550	Tursiops truncatus	32.51	1.00e-27	117.00
IUUC-Vpa-130800	Vicugna pacos	30.68	2.00e-17	84.30
IUUC-Xtr-132108	Xenopus tropicalis	31.43	2.00e-21	97.80

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence