iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Fca-035659

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AANG02070895

Gene Name

KLHL8

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFCAG00000013928.3	ENSFCAT00000013933.3	ENSFCAP00000012916.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	3.00e-17	62.8	66	131
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	1.80e-09	36.8	165	196

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgklde 67
           +Dv+l+vg + +++hk+vLa   ++F+a+fl+e+ e k +  +ei+d + ++ ++l+kF+Y+++l++
   Q: 66   CDVTLKVGSKLISCHKLVLACVIPYFRAMFLSEMAEAK-QTLIEIRDFDGDAIEDLVKFVYSSRLTL 131
           9************************************9.*************************986 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfilkhFk 32
           ++Ncl++++fA+ ++  dL+d a+ +++ hF+
   Q: 165  PSNCLAVRAFAESHNRIDLMDMADQYACEHFT 196
           89*****************************7 PP

Organism

Felis catus

Protein Sequence
(Fasta)

MASESVNAKQ ARNHCTKGKR QQHQQIKNRS SISDGDGEDS FIFEANEAWK DFHGSLLRFY 60
ENGELCDVTL KVGSKLISCH KLVLACVIPY FRAMFLSEMA EAKQTLIEIR DFDGDAIEDL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCGCGCGCTT CTCCCGCCGC GCTAGAGGCC GCCGTTCTCG GGGCTGAGCC GAGAGGAAGC 60
CCGGCGCCCG CCAGGGCTCT ACGGGGCCGC GCAGGAGGGC GCGCGTCCGT CGGGTGCTCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR030605--KLHL8
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0005654--C:nucleoplasm
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process

KEGG

fca:101096725

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001443	Ailuropoda melanoleuca	99.35	0.00e+00	1262.00
IUUC-Atr-002726	Amborella trichopoda	35.08	1.00e-42	168.00
IUUC-Apl-003978	Anas platyrhynchos	90.16	0.00e+00	1164.00
IUUC-Aca-004958	Anolis carolinensis	85.48	0.00e+00	1088.00
IUUC-Ame-011139	Astyanax mexicanus	81.91	0.00e+00	1070.00
IUUC-Bta-013142	Bos taurus	97.25	0.00e+00	1233.00
IUUC-Bdi-014143	Brachypodium distachyon	39.58	3.00e-43	169.00
IUUC-Cel-018551	Caenorhabditis elegans	42.27	1.00e-130	460.00
IUUC-Cja-019650	Callithrix jacchus	97.58	0.00e+00	1264.00
IUUC-Cfa-021046	Canis familiaris	99.52	0.00e+00	1259.00
IUUC-Cpo-022445	Cavia porcellus	94.51	0.00e+00	1177.00
IUUC-Csa-023642	Chlorocebus sabaeus	98.39	0.00e+00	1275.00
IUUC-Cho-025012	Choloepus hoffmanni	79.90	0.00e+00	894.00
IUUC-Dre-027723	Danio rerio	82.27	0.00e+00	1061.00
IUUC-Dno-028964	Dasypus novemcinctus	97.27	0.00e+00	1036.00
IUUC-Dor-030899	Dipodomys ordii	83.44	4.00e-137	481.00
IUUC-Ete-032815	Echinops telfairi	93.54	0.00e+00	1219.00
IUUC-Eca-034162	Equus caballus	98.06	0.00e+00	1222.00
IUUC-Eeu-034660	Erinaceus europaeus	95.15	0.00e+00	1208.00
IUUC-Fal-037619	Ficedula albicollis	90.47	0.00e+00	1174.00
IUUC-Gmo-038546	Gadus morhua	85.10	0.00e+00	1056.00
IUUC-Ggr-040041	Gaeumannomyces graminis	31.29	2.00e-07	49.70
IUUC-Gga-040770	Gallus gallus	90.81	0.00e+00	1144.00
IUUC-Gac-042557	Gasterosteus aculeatus	78.56	0.00e+00	1043.00
IUUC-Gma-043533	Glycine max	30.83	1.00e-37	151.00
IUUC-Ggo-044741	Gorilla gorilla	98.06	0.00e+00	1272.00
IUUC-Hsa-046025	Homo sapiens	97.90	0.00e+00	1271.00
IUUC-Itr-048541	Ictidomys tridecemlineatus	98.54	0.00e+00	1110.00
IUUC-Lpe-051276	Leersia perrieri	33.33	2.00e-39	157.00
IUUC-Loc-052834	Lepisosteus oculatus	82.88	0.00e+00	1010.00
IUUC-Laf-054513	Loxodonta africana	97.58	0.00e+00	1239.00
IUUC-Mcc-054707	Macaca mulatta	98.23	0.00e+00	1271.00
IUUC-Meu-056779	Macropus eugenii	90.35	0.00e+00	1164.00
IUUC-Mga-059676	Meleagris gallopavo	90.65	0.00e+00	1143.00
IUUC-Mmr-061359	Microcebus murinus	96.77	0.00e+00	1219.00
IUUC-Mdo-062527	Monodelphis domestica	89.41	0.00e+00	1159.00
IUUC-Mmu-063112	Mus musculus	93.00	0.00e+00	1217.00
IUUC-Mac-064682	Musa acuminata	35.93	5.00e-42	166.00
IUUC-Mpu-065800	Mustela putorius furo	98.87	0.00e+00	1256.00
IUUC-Mlu-067536	Myotis lucifugus	96.58	0.00e+00	1186.00
IUUC-Nle-069397	Nomascus leucogenys	98.06	0.00e+00	1271.00
IUUC-Opr-070599	Ochotona princeps	96.48	0.00e+00	1036.00
IUUC-Ont-072580	Oreochromis niloticus	81.95	0.00e+00	1058.00
IUUC-Oan-073180	Ornithorhynchus anatinus	91.76	0.00e+00	1177.00
IUUC-Ocu-074026	Oryctolagus cuniculus	97.42	0.00e+00	1217.00
IUUC-Obr-076181	Oryza brachyantha	32.03	5.00e-36	146.00
IUUC-Ola-086776	Oryzias latipes	80.88	0.00e+00	1019.00
IUUC-Oga-088651	Otolemur garnettii	97.26	0.00e+00	1228.00
IUUC-Oar-089567	Ovis aries	96.12	0.00e+00	1209.00
IUUC-Ptr-091564	Pan troglodytes	98.06	0.00e+00	1272.00
IUUC-Pan-092578	Papio anubis	98.39	0.00e+00	1275.00
IUUC-Psi-093635	Pelodiscus sinensis	89.26	0.00e+00	1108.00
IUUC-Pma-094660	Petromyzon marinus	61.82	0.00e+00	761.00
IUUC-Pfo-097507	Poecilia formosa	80.52	0.00e+00	988.00
IUUC-Pab-098025	Pongo abelii	98.06	0.00e+00	1272.00
IUUC-Pca-101046	Procavia capensis	87.40	0.00e+00	635.00
IUUC-Ppe-101154	Prunus persica	32.90	3.00e-38	153.00
IUUC-Pva-102359	Pteropus vampyrus	98.18	0.00e+00	910.00
IUUC-Rno-105750	Rattus norvegicus	93.72	0.00e+00	1197.00
IUUC-Sha-107513	Sarcophilus harrisii	92.42	0.00e+00	1199.00
IUUC-Sly-111482	Solanum lycopersicum	31.52	2.00e-41	163.00
IUUC-Stu-112032	Solanum tuberosum	32.68	7.00e-43	168.00
IUUC-Sar-113616	Sorex araneus	70.99	3.00e-118	419.00
IUUC-Ssc-116205	Sus scrofa	97.85	0.00e+00	1047.00
IUUC-Tgu-117435	Taeniopygia guttata	90.63	0.00e+00	1167.00
IUUC-Tru-118709	Takifugu rubripes	81.43	0.00e+00	1055.00
IUUC-Tsy-119466	Tarsius syrichta	98.91	0.00e+00	1111.00
IUUC-Tni-119988	Tetraodon nigroviridis	81.13	0.00e+00	1048.00
IUUC-Tae-124761	Triticum aestivum	34.80	5.00e-39	156.00
IUUC-Tbe-127704	Tupaia belangeri	97.26	0.00e+00	1070.00
IUUC-Ttr-128892	Tursiops truncatus	98.27	0.00e+00	929.00
IUUC-Vpa-130545	Vicugna pacos	98.63	0.00e+00	1056.00
IUUC-Xtr-132289	Xenopus tropicalis	83.82	0.00e+00	1034.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence