iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Bra-016853

Ensembl Protein ID

Bra021231.1-P

UniProt Accession

M4DXI5; M4DXI5_BRARP

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
Bra021231	Bra021231.1	Bra021231.1-P

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	5.30e-107	359.1	691	1031

Active Site

Position(s)	Description	Evidence
999	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 2    ksdlkkrlevefvg.....EegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlldl 90
           ++dl+  ++v+fv+     E+g+d gG++++f+++++ + ++ ++glf  +e+ +++l+pnp sg+ + +hl++F+flG ll+ka+++g l+dl
   Q: 691  EDDLRGPIRVTFVNelgveEAGIDGGGIFKDFMEKITLAAFDVQYGLF--KETVDHMLYPNPGSGMIHGQHLQFFHFLGSLLAKAMFEGILVDL 782
           6899999*******9999999***************************..5566889999999999999************************* PP
   S: 91   plsksfyklllgkklsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVtneNkeeYvklvveyrlke 184
           p++++f+++l +k   l+dl+++dpely++l ++k++ + di++  l+l f + ++++ge++eeeL+pgG++++Vtn+N   +++lv ++rl+ 
   Q: 783  PFATFFLSKLKQKYNYLNDLPSLDPELYRHLIFLKRY-KGDISD--LELYFVILNNEYGERTEEELLPGGKDMRVTNKNVITFIHLVSNHRLNF 873
           *************9999********************.668887..69999999**************************************** PP
   S: 185  gikeqveafreGfneviplellslFteeelellicGe.eeidvedlkketkykggytedspaiqwFwevleefsseerkafLqFvTgssrlPlg 277
           +i++q  +f +Gf+++ip e++++F+e+el++li+G+ +++d++dl+++t+y ggy++ + +i++Fwev+++fs e++k+fL+FvTg+sr Pl 
   Q: 874  QIRQQSSHFLRGFQQLIPREWIDMFNEHELQVLISGSaDSLDIDDLRENTNYSGGYNAGHYVIDMFWEVMKSFSTENQKKFLKFVTGCSRGPLL 967
           *************************************9******************************************************** PP
   S: 278  Gfaelkprlfvirk......dasddrlPssnTCfnyLkLPeYsskeilkekLlyAieetkgFels 336
           Gf++l+p  f+i++      +++ drlP+s TC+n+LkLP+Y+ske+l+ kL+yAi+ ++gF+ls
   Q: 968  GFKYLEPA-FCIQRaggsvsNEAVDRLPTSATCMNLLKLPPYQSKEQLETKLMYAISAEAGFDLS 1031
           ******88.888888***988888**************************************985 PP

Organism

Brassica rapa

Protein Sequence
(Fasta)

MFFSGDPSTR KRVDLGGRST KEGDARKLLE QTKMERNRRL LQKKHNSAAL KIQKVFRGRR 60
STAIVRSKVR RDFCETYGDN CQNVDRHCFE PASSFLPQFL FFFKAQSSGD FVMLVETCRL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTTTTTCT CCGGCGATCC GTCGACTCGG AAGCGTGTCG ATTTAGGTGG CCGGAGCACC 60
AAGGAAGGAG ATGCCCGCAA GCTTCTTGAG CAGACCAAGA TGGAGCGCAA TCGTCGTCTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000569--HECT_dom
IPR000048--IQ_motif_EF-hand-BS

PROSITE

PS50237--HECT
PS50096--IQ

Pfam

PF00632--HECT

SMART

SM00119--HECTc

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001355	Ailuropoda melanoleuca	46.60	2.00e-105	377.00
IUUC-Apl-003731	Anas platyrhynchos	47.57	5.00e-110	392.00
IUUC-Aca-005248	Anolis carolinensis	47.09	5.00e-109	389.00
IUUC-Ame-010769	Astyanax mexicanus	41.04	6.00e-76	278.00
IUUC-Bta-012841	Bos taurus	47.33	1.00e-107	384.00
IUUC-Bci-013743	Botrytis cinerea	39.10	6.00e-82	299.00
IUUC-Bol-015390	Brassica oleracea	97.48	0.00e+00	2024.00
IUUC-Cja-019743	Callithrix jacchus	46.08	3.00e-104	372.00
IUUC-Cfa-021031	Canis familiaris	46.60	8.00e-106	378.00
IUUC-Cpo-022401	Cavia porcellus	46.60	1.00e-105	377.00
IUUC-Cre-022725	Chlamydomonas reinhardtii	44.61	9.00e-98	350.00
IUUC-Csa-024107	Chlorocebus sabaeus	46.12	5.00e-105	375.00
IUUC-Cho-024750	Choloepus hoffmanni	48.83	2.00e-93	337.00
IUUC-Cme-027265	Cyanidioschyzon merolae	40.45	5.00e-105	375.00
IUUC-Dre-028196	Danio rerio	47.33	2.00e-108	386.00
IUUC-Dno-029024	Dasypus novemcinctus	47.09	6.00e-107	382.00
IUUC-Eca-033828	Equus caballus	46.84	1.00e-106	380.00
IUUC-Fca-035907	Felis catus	46.60	1.00e-105	377.00
IUUC-Fal-037389	Ficedula albicollis	47.33	3.00e-109	389.00
IUUC-Ggr-039941	Gaeumannomyces graminis	39.91	4.00e-83	303.00
IUUC-Gga-040310	Gallus gallus	47.33	7.00e-109	388.00
IUUC-Ggo-045031	Gorilla gorilla	46.36	2.00e-105	377.00
IUUC-Hsa-045880	Homo sapiens	46.36	2.00e-105	377.00
IUUC-Kpa-049307	Komagataella pastoris	37.03	1.00e-68	254.00
IUUC-Loc-052218	Lepisosteus oculatus	46.99	1.00e-106	380.00
IUUC-Mcc-055127	Macaca mulatta	46.36	1.00e-105	377.00
IUUC-Mla-059124	Melampsora laricipopulina	45.30	1.00e-95	343.00
IUUC-Mga-059581	Meleagris gallopavo	47.33	4.00e-109	389.00
IUUC-Mmr-061360	Microcebus murinus	46.60	1.00e-105	377.00
IUUC-Mdo-062194	Monodelphis domestica	47.33	5.00e-108	385.00
IUUC-Mmu-064189	Mus musculus	46.60	6.00e-105	375.00
IUUC-Mac-065275	Musa acuminata	59.32	0.00e+00	1024.00
IUUC-Mpu-066439	Mustela putorius furo	46.84	1.00e-106	381.00
IUUC-Mlu-068228	Myotis lucifugus	47.33	9.00e-108	384.00
IUUC-Nle-069687	Nomascus leucogenys	46.08	3.00e-104	372.00
IUUC-Ont-071836	Oreochromis niloticus	47.23	1.00e-107	384.00
IUUC-Oan-072800	Ornithorhynchus anatinus	47.57	4.00e-109	389.00
IUUC-Ocu-074587	Oryctolagus cuniculus	46.60	8.00e-106	378.00
IUUC-Ola-087209	Oryzias latipes	46.27	4.00e-107	382.00
IUUC-Olu-087699	Ostreococcus lucimarinus	48.50	5.00e-101	360.00
IUUC-Oga-088776	Otolemur garnettii	46.36	1.00e-104	374.00
IUUC-Oar-089441	Ovis aries	47.33	8.00e-108	385.00
IUUC-Ptr-091273	Pan troglodytes	46.36	2.00e-105	377.00
IUUC-Pan-091981	Papio anubis	46.36	2.00e-105	377.00
IUUC-Pma-094738	Petromyzon marinus	38.19	3.00e-109	389.00
IUUC-Pno-095132	Phaeosphaeria nodorum	36.39	2.00e-58	220.00
IUUC-Pfo-097511	Poecilia formosa	47.23	2.00e-108	386.00
IUUC-Pca-100987	Procavia capensis	47.24	2.00e-100	360.00
IUUC-Pgr-103513	Puccinia graminis	43.56	2.00e-92	334.00
IUUC-Ptt-103967	Puccinia triticina	41.58	1.00e-82	301.00
IUUC-Pte-104105	Pyrenophora teres	38.28	1.00e-79	291.00
IUUC-Pyt-104449	Pyrenophora triticirepentis	38.28	3.00e-79	290.00
IUUC-Sja-107889	Schizosaccharomyces japonicus	36.46	2.00e-96	347.00
IUUC-Spo-108097	Schizosaccharomyces pombe	37.41	1.00e-99	357.00
IUUC-Sar-113687	Sorex araneus	42.46	6.00e-61	228.00
IUUC-Tgu-116729	Taeniopygia guttata	47.09	2.00e-108	387.00
IUUC-Tru-118068	Takifugu rubripes	47.47	3.00e-107	383.00
IUUC-Tsy-118942	Tarsius syrichta	50.96	4.00e-72	266.00
IUUC-Tme-127102	Tuber melanosporum	38.72	4.00e-80	293.00
IUUC-Tbe-127351	Tupaia belangeri	45.87	3.00e-88	320.00
IUUC-Xtr-132094	Xenopus tropicalis	46.84	7.00e-107	381.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence