iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ago-007875

Ensembl Protein ID

AAS50783

UniProt Accession

Q75DK8; Q75DK8_ASHGO

Genbank Protein ID

AAS50783.2

Protein Name

ABR013Wp

Genbank Nucleotide ID

AE016815

Gene Name

AGOS_ABR013W

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
AGOS_ABR013W	AAS50783	AAS50783

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	1.50e-72	242.7	1078	1422

Active Site

Position(s)	Description	Evidence
1391	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 6    kkrlevefvgEegldlgGvtreflallskelqnpdlglflysen.....dketlqpnpdsglknp.ehlklFeflGrllgkalqdgrlldlplsksfyk 98
            ++le+e+++E g+++ G+t+ef+a +ske+ +++lg++  s+       +  l+p+p s   n  +  +lF+ lG++++ ++ d+r+ld +++++f+ 
   Q: 1078 PSVLEIEYQDEVGIGM-GPTLEFYASVSKEFARKSLGMWHGSSVpgddfLDGLLFPAPLSPKRNGaKIYELFTHLGTFVARSMLDNRILDFRFNRVFFD 1175
           5799************.**********************544444333667788888888755446999****************************** PP
   S: 99   lllgk..........klsl.edleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVtneNkeeYvklvveyrlkegi 186
           l+ +           + +l e l  +dp+l+ksl +++e + +  + ++++l+f+     ++ ++ + L++gG+n+pVt +N+e Yv +v+++ l +g+
   Q: 1176 LMHTAarreeldfahPAKLlESLRLIDPQLAKSLAFVREPR-NWPDLESMALSFT-----VPGYDFD-LVEGGANTPVTAANAELYVARVLDAFLGSGV 1267
           **666556666666578877******************984.5556666788887.....5666666.******************************* PP
   S: 187  keqveafreGfneviplellslFteeelellicGe.eeidvedlkketkykggytedspaiqwFwevleefsseerkafLqFvTgssrlPlgGfaelkp 284
           ++q+ af eGf++ +p ++l ++t+ el+ l     e+++ve+l + ++ ++gy+ dsp+++ ++ v+ +f+++ r+ fLqF+Tgs++lP+gGf++lkp
   Q: 1268 RQQLRAFMEGFSRAFPYSSLLVLTPDELSELYGRVeEDWSVETLYSYITADHGYSMDSPTLHDLIAVMAAFDQHHRRLFLQFLTGSPKLPVGGFKNLKP 1366
           *****************************99877789************************************************************** PP
   S: 285  rlfvirk.....dasddrlPssnTCfnyLkLPeYsskeilkekLlyAieet.kgFe 334
            l+v+ k      + d+ lPs++TC+nyLkLP+Yss e+l+ ++  Ai+e+  +F 
   Q: 1367 HLTVVLKhpegdLSPDQYLPSVMTCANYLKLPKYSSREVLRARIVHAIHEGsGAFL 1422
           *********9966667**********************************977775 PP

Organism

Ashbya gossypii

Protein Sequence
(Fasta)

MNRGDEEYDQ DGDYAVSGME DFGETQLDSQ ESGDDDSNAE YSYPEEEGDY SNYYNEYGDE 60
DAEEDAEEEE REDTEAVGRG PGGRPDRWVS SLQELLGTLA QGLEARRAGE DGGARRVNLA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAATCGAG GGGACGAGGA GTACGACCAG GACGGGGACT ACGCCGTCAG CGGGATGGAG 60
GACTTCGGGG AGACGCAACT GGACAGCCAG GAATCCGGAG ACGACGACAG CAACGCGGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR011989--ARM-like
IPR016024--ARM-type_fold
IPR000569--HECT_dom

PROSITE

PS50237--HECT

Pfam

PF00632--HECT

SMART

SM00119--HECTc

Gene Ontology

GO:0005737--C:cytoplasm
GO:0004842--F:ubiquitin-protein transferase activity
GO:0010994--P:free ubiquitin chain polymerization
GO:0051974--P:negative regulation of telomerase activity

KEGG

ago:AGOS_ABR013W

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000750	Aegilops tauschii	35.95	2.00e-83	302.00
IUUC-Aml-001502	Ailuropoda melanoleuca	36.20	1.00e-82	300.00
IUUC-Atr-002821	Amborella trichopoda	35.24	2.00e-84	306.00
IUUC-Apl-003531	Anas platyrhynchos	34.83	3.00e-75	275.00
IUUC-Aca-004521	Anolis carolinensis	40.11	5.00e-32	132.00
IUUC-Aly-005962	Arabidopsis lyrata	35.99	5.00e-83	301.00
IUUC-Ath-006636	Arabidopsis thaliana	35.78	5.00e-83	301.00
IUUC-Acl-008242	Aspergillus clavatus	41.52	2.00e-124	439.00
IUUC-Afl-008736	Aspergillus flavus	40.95	8.00e-123	433.00
IUUC-Afu-008812	Aspergillus fumigatus	43.00	8.00e-127	446.00
IUUC-Ani-009407	Aspergillus nidulans	41.18	7.00e-125	440.00
IUUC-Ang-009763	Aspergillus niger	39.58	2.00e-115	409.00
IUUC-Aor-009941	Aspergillus oryzae	37.57	6.00e-136	476.00
IUUC-Ate-010459	Aspergillus terreus	39.33	6.00e-103	367.00
IUUC-Ame-011761	Astyanax mexicanus	36.58	2.00e-83	303.00
IUUC-Bgr-012265	Blumeria graminis	40.19	2.00e-122	432.00
IUUC-Bta-013070	Bos taurus	36.20	9.00e-83	300.00
IUUC-Bci-013890	Botrytis cinerea	47.17	1.00e-123	436.00
IUUC-Bdi-014046	Brachypodium distachyon	35.69	4.00e-82	298.00
IUUC-Bol-015942	Brassica oleracea	34.56	9.00e-78	283.00
IUUC-Bra-016849	Brassica rapa	34.56	4.00e-78	285.00
IUUC-Cel-018153	Caenorhabditis elegans	32.21	6.00e-68	251.00
IUUC-Cja-019046	Callithrix jacchus	36.20	2.00e-82	299.00
IUUC-Cfa-020521	Canis familiaris	36.01	4.00e-82	298.00
IUUC-Cpo-021639	Cavia porcellus	35.87	2.00e-82	300.00
IUUC-Cre-022767	Chlamydomonas reinhardtii	35.91	2.00e-74	271.00
IUUC-Csa-023231	Chlorocebus sabaeus	36.20	2.00e-82	299.00
IUUC-Cho-024380	Choloepus hoffmanni	37.16	3.00e-67	249.00
IUUC-Cin-025482	Ciona intestinalis	32.32	7.00e-71	259.00
IUUC-Csv-026121	Ciona savignyi	33.40	7.00e-73	267.00
IUUC-Cgl-026716	Colletotrichum gloeosporioides	41.75	3.00e-126	444.00
IUUC-Cne-026857	Cryptococcus neoformans	44.94	7.00e-106	377.00
IUUC-Cme-027226	Cyanidioschyzon merolae	32.02	9.00e-61	227.00
IUUC-Dre-028174	Danio rerio	36.26	2.00e-82	299.00
IUUC-Dno-029954	Dasypus novemcinctus	37.91	3.00e-30	126.00
IUUC-Dor-030939	Dipodomys ordii	32.49	1.00e-65	243.00
IUUC-Dse-031444	Dothistroma septosporum	43.06	3.00e-127	448.00
IUUC-Dme-031739	Drosophila melanogaster	29.57	3.00e-59	223.00
IUUC-Ete-032345	Echinops telfairi	30.33	2.00e-55	209.00
IUUC-Eca-033229	Equus caballus	36.20	1.00e-82	300.00
IUUC-Eeu-035205	Erinaceus europaeus	36.20	1.00e-80	293.00
IUUC-Fca-036444	Felis catus	36.20	2.00e-82	300.00
IUUC-Fal-037131	Ficedula albicollis	36.06	4.00e-83	301.00
IUUC-Fox-038035	Fusarium oxysporum	42.02	3.00e-125	440.00
IUUC-Fso-038320	Fusarium solani	41.49	4.00e-124	437.00
IUUC-Gmo-039497	Gadus morhua	36.65	3.00e-83	301.00
IUUC-Ggr-040057	Gaeumannomyces graminis	47.09	5.00e-121	427.00
IUUC-Gga-041021	Gallus gallus	36.20	2.00e-83	302.00
IUUC-Gac-042474	Gasterosteus aculeatus	36.65	2.00e-83	302.00
IUUC-Gma-043715	Glycine max	33.70	2.00e-76	279.00
IUUC-Ggo-044855	Gorilla gorilla	36.20	2.00e-82	299.00
IUUC-Hsa-046147	Homo sapiens	36.20	1.00e-82	300.00
IUUC-Hvu-047811	Hordeum vulgare	37.10	3.00e-84	305.00
IUUC-Itr-048131	Ictidomys tridecemlineatus	36.20	1.00e-82	300.00
IUUC-Kpa-049098	Komagataella pastoris	38.58	7.00e-139	486.00
IUUC-Lch-049818	Latimeria chalumnae	35.46	9.00e-81	293.00
IUUC-Lpe-051017	Leersia perrieri	35.92	3.00e-80	292.00
IUUC-Loc-051777	Lepisosteus oculatus	36.84	1.00e-83	303.00
IUUC-Lma-052990	Leptosphaeria maculans	41.56	5.00e-123	434.00
IUUC-Laf-053727	Loxodonta africana	35.87	2.00e-82	299.00
IUUC-Mcc-055799	Macaca mulatta	36.20	2.00e-82	299.00
IUUC-Meu-056065	Macropus eugenii	33.41	2.00e-60	226.00
IUUC-Mor-057054	Magnaporthe oryzae	38.69	1.00e-118	419.00
IUUC-Mpo-057417	Magnaporthe poae	40.47	4.00e-120	424.00
IUUC-Mtr-057849	Medicago truncatula	35.07	1.00e-79	290.00
IUUC-Mla-058870	Melampsora laricipopulina	41.70	4.00e-97	348.00
IUUC-Mga-059580	Meleagris gallopavo	33.21	3.00e-33	135.00
IUUC-Mvi-060507	Microbotryum violaceum	38.13	8.00e-107	380.00
IUUC-Mmr-060816	Microcebus murinus	35.81	3.00e-81	295.00
IUUC-Mdo-062866	Monodelphis domestica	33.56	2.00e-61	229.00
IUUC-Mmu-063906	Mus musculus	35.62	2.00e-80	292.00
IUUC-Mac-065046	Musa acuminata	33.56	2.00e-82	299.00
IUUC-Mpu-066199	Mustela putorius furo	36.20	1.00e-82	300.00
IUUC-Mlu-067110	Myotis lucifugus	35.81	8.00e-81	294.00
IUUC-Nfi-068482	Neosartorya fischeri	42.67	5.00e-126	444.00
IUUC-Ncr-068906	Neurospora crassa	47.59	6.00e-125	440.00
IUUC-Nle-069410	Nomascus leucogenys	36.20	2.00e-82	299.00
IUUC-Opr-070401	Ochotona princeps	38.10	9.00e-36	144.00
IUUC-Ont-072100	Oreochromis niloticus	36.26	3.00e-83	301.00
IUUC-Oan-073121	Ornithorhynchus anatinus	36.01	2.00e-81	295.00
IUUC-Ocu-074623	Oryctolagus cuniculus	36.20	1.00e-82	300.00
IUUC-Oba-075380	Oryza barthii	36.69	7.00e-82	296.00
IUUC-Obr-076915	Oryza brachyantha	35.34	3.00e-78	285.00
IUUC-Ogl-076926	Oryza glaberrima	36.69	6.00e-82	297.00
IUUC-Ogu-078892	Oryza glumaepatula	36.90	3.00e-82	298.00
IUUC-Oin-079256	Oryza indica	35.10	7.00e-78	284.00
IUUC-Olo-081086	Oryza longistaminata	36.40	2.00e-79	288.00
IUUC-Ome-081422	Oryza meridionalis	34.91	1.00e-78	286.00
IUUC-Oni-083047	Oryza nivara	37.30	4.00e-83	301.00
IUUC-Opu-083641	Oryza punctata	36.29	2.00e-81	295.00
IUUC-Oru-084439	Oryza rufipogon	36.90	3.00e-82	298.00
IUUC-Osa-085617	Oryza sativa	36.90	5.00e-81	292.00
IUUC-Ola-087173	Oryzias latipes	36.45	2.00e-82	299.00
IUUC-Olu-087871	Ostreococcus lucimarinus	33.74	3.00e-74	270.00
IUUC-Oga-087908	Otolemur garnettii	36.01	1.00e-81	296.00
IUUC-Oar-090277	Ovis aries	36.20	6.00e-83	301.00
IUUC-Ptr-091543	Pan troglodytes	36.20	1.00e-82	300.00
IUUC-Pan-092243	Papio anubis	36.20	2.00e-82	299.00
IUUC-Psi-093150	Pelodiscus sinensis	35.87	4.00e-82	298.00
IUUC-Pno-094891	Phaeosphaeria nodorum	41.67	3.00e-123	434.00
IUUC-Ppa-095181	Physcomitrella patens	35.14	1.00e-78	285.00
IUUC-Pfo-096267	Poecilia formosa	36.65	3.00e-84	305.00
IUUC-Pab-098072	Pongo abelii	36.20	2.00e-82	299.00
IUUC-Pop-099190	Populus trichocarpa	35.51	2.00e-82	299.00
IUUC-Pca-100311	Procavia capensis	36.01	1.00e-82	300.00
IUUC-Ppe-101284	Prunus persica	34.97	6.00e-82	298.00
IUUC-Pva-102215	Pteropus vampyrus	33.33	1.00e-69	257.00
IUUC-Pgr-103694	Puccinia graminis	36.76	8.00e-98	350.00
IUUC-Ptt-103916	Puccinia triticina	40.33	5.00e-90	324.00
IUUC-Pte-104346	Pyrenophora teres	42.44	5.00e-126	444.00
IUUC-Pyt-104508	Pyrenophora triticirepentis	42.28	1.00e-125	442.00
IUUC-Rno-105315	Rattus norvegicus	36.20	2.00e-82	299.00
IUUC-Sce-106273	Saccharomyces cerevisiae	44.28	0.00e+00	1078.00
IUUC-Sha-106835	Sarcophilus harrisii	36.01	2.00e-81	296.00
IUUC-Sja-107943	Schizosaccharomyces japonicus	36.50	6.00e-113	400.00
IUUC-Spo-108081	Schizosaccharomyces pombe	44.94	3.00e-107	381.00
IUUC-Ssl-108560	Sclerotinia sclerotiorum	41.11	5.00e-125	441.00
IUUC-Smo-109590	Selaginella moellendorffii	37.13	7.00e-85	307.00
IUUC-Sit-110717	Setaria italica	35.62	2.00e-83	303.00
IUUC-Sly-111557	Solanum lycopersicum	36.06	6.00e-84	304.00
IUUC-Stu-112896	Solanum tuberosum	36.19	1.00e-73	269.00
IUUC-Sar-113224	Sorex araneus	37.57	6.00e-61	228.00
IUUC-Sbi-113884	Sorghum bicolor	36.05	5.00e-86	310.00
IUUC-Sre-114993	Sporisorium reilianum	38.98	2.00e-118	419.00
IUUC-Ssc-115535	Sus scrofa	34.95	1.00e-70	260.00
IUUC-Tgu-117167	Taeniopygia guttata	40.11	1.00e-32	133.00
IUUC-Tru-118669	Takifugu rubripes	36.65	2.00e-83	302.00
IUUC-Tsy-119373	Tarsius syrichta	30.41	9.00e-48	184.00
IUUC-Tni-120049	Tetraodon nigroviridis	52.24	3.00e-35	140.00
IUUC-Tca-121779	Theobroma cacao	34.36	1.00e-81	296.00
IUUC-Tre-122195	Trichoderma reesei	43.09	4.00e-126	444.00
IUUC-Tvi-122650	Trichoderma virens	42.19	7.00e-125	440.00
IUUC-Tae-123120	Triticum aestivum	36.19	7.00e-83	300.00
IUUC-Tur-126295	Triticum urartu	35.76	5.00e-83	301.00
IUUC-Tme-126964	Tuber melanosporum	42.53	4.00e-124	437.00
IUUC-Tbe-128149	Tupaia belangeri	33.99	5.00e-48	185.00
IUUC-Ttr-128165	Tursiops truncatus	36.06	9.00e-83	300.00
IUUC-Uma-129365	Ustilago maydis	45.42	1.00e-108	387.00
IUUC-Vda-129725	Verticillium dahliae	47.28	1.00e-125	442.00
IUUC-Vpa-130678	Vicugna pacos	36.20	1.00e-82	300.00
IUUC-Vvi-131539	Vitis vinifera	35.17	5.00e-83	301.00
IUUC-Xtr-132636	Xenopus tropicalis	36.31	3.00e-81	295.00
IUUC-Xma-133458	Xiphophorus maculatus	36.65	3.00e-84	305.00
IUUC-Yli-134481	Yarrowia lipolytica	42.79	4.00e-121	427.00
IUUC-Zma-135657	Zea mays	34.65	7.00e-84	304.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence