iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oga-087979

Ensembl Protein ID

ENSOGAP00000005428.2

UniProt Accession

H0WTF1; H0WTF1_OTOGA

Genbank Protein ID

ENSOGAP00000005428

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAQR03055854

Gene Name

MYLIP

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOGAG00000006071.2	ENSOGAT00000006073.2	ENSOGAP00000005428.2

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	98.20	0.00e+00	885.00	IUUC-Hsa-046869

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Otolemur garnettii

Protein Sequence
(Fasta)

MLCYVTRPDA VLMEVEVEAK ANGEDCLNQV CRRLGIIEVD YFGLQFTGSK GESLWLNLRN 60
RISQQMDGLA PYRLKLRVKF FVEPHLILQE QTRHIFFLHI KEALLAGHLL CSPEQAVELS 120

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Nucleotide Sequence
(Fasta)

CCGGGCTTGG TGTCCAAGCT GTGCCGAAGC GGCAGCCCCC AGCGCACCAA AGAGGAGGCG 60
GCTGTGGCGG CAGCGGCGGC CCCAGCCATG CTGTGCTATG TGACGAGGCC GGACGCGGTG 120

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Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR019749--Band_41_domain
IPR000798--Ez/rad/moesin-like
IPR014352--FERM/acyl-CoA-bd_prot_3-hlx
IPR019748--FERM_central
IPR000299--FERM_domain
IPR018979--FERM_N
IPR018980--FERM_PH-like_C
IPR011993--PH_dom-like
IPR029071--Ubiquitin-rel_dom
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50057--FERM_3
PS50089--ZF_RING_2

Pfam

PF09380--FERM_C
PF00373--FERM_M
PF09379--FERM_N

PRINTS

PR00935--BAND41
PR00661--ERMFAMILY

SMART

SM00295--B41
SM01196--FERM_C

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005856--C:cytoskeleton
GO:0019898--C:extrinsic component of membrane
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0042632--P:cholesterol homeostasis
GO:0010989--P:negative regulation of low-density lipoprotein particle clearance
GO:0007399--P:nervous system development
GO:0045732--P:positive regulation of protein catabolic process
GO:0031648--P:protein destabilization
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0032803--P:regulation of low-density lipoprotein particle receptor catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001425	Ailuropoda melanoleuca	95.91	0.00e+00	814.00
IUUC-Apl-003704	Anas platyrhynchos	91.41	0.00e+00	774.00
IUUC-Aca-004645	Anolis carolinensis	89.66	0.00e+00	778.00
IUUC-Ame-011401	Astyanax mexicanus	75.23	0.00e+00	655.00
IUUC-Bta-012752	Bos taurus	94.21	0.00e+00	707.00
IUUC-Cja-019734	Callithrix jacchus	97.53	0.00e+00	853.00
IUUC-Cfa-020145	Canis familiaris	96.58	0.00e+00	744.00
IUUC-Cpo-021436	Cavia porcellus	95.79	0.00e+00	719.00
IUUC-Csa-024248	Chlorocebus sabaeus	98.20	0.00e+00	857.00
IUUC-Cho-024528	Choloepus hoffmanni	83.82	0.00e+00	679.00
IUUC-Cin-025748	Ciona intestinalis	36.33	6.00e-47	180.00
IUUC-Csv-025837	Ciona savignyi	38.43	1.00e-90	327.00
IUUC-Dre-027847	Danio rerio	76.01	0.00e+00	669.00
IUUC-Dno-029860	Dasypus novemcinctus	94.74	0.00e+00	696.00
IUUC-Dor-030664	Dipodomys ordii	83.60	0.00e+00	709.00
IUUC-Dse-031509	Dothistroma septosporum	43.14	4.00e-09	57.00
IUUC-Dme-031990	Drosophila melanogaster	31.23	9.00e-38	151.00
IUUC-Ete-032496	Echinops telfairi	76.41	1.00e-149	522.00
IUUC-Eca-033674	Equus caballus	95.32	0.00e+00	870.00
IUUC-Eeu-035048	Erinaceus europaeus	87.87	0.00e+00	779.00
IUUC-Fca-036547	Felis catus	95.67	0.00e+00	813.00
IUUC-Fal-037504	Ficedula albicollis	91.85	0.00e+00	761.00
IUUC-Fox-037905	Fusarium oxysporum	28.79	3.00e-03	34.30
IUUC-Gmo-038660	Gadus morhua	74.71	3.00e-154	538.00
IUUC-Gga-040123	Gallus gallus	92.13	0.00e+00	809.00
IUUC-Gac-042073	Gasterosteus aculeatus	72.77	0.00e+00	632.00
IUUC-Ggo-045387	Gorilla gorilla	98.20	0.00e+00	859.00
IUUC-Hsa-046869	Homo sapiens	98.20	0.00e+00	867.00
IUUC-Itr-047917	Ictidomys tridecemlineatus	95.06	0.00e+00	833.00
IUUC-Lch-049990	Latimeria chalumnae	82.70	0.00e+00	776.00
IUUC-Loc-051908	Lepisosteus oculatus	75.89	0.00e+00	675.00
IUUC-Lma-053223	Leptosphaeria maculans	52.50	2.00e-08	55.10
IUUC-Laf-053915	Loxodonta africana	94.83	0.00e+00	833.00
IUUC-Mcc-054865	Macaca mulatta	97.98	0.00e+00	855.00
IUUC-Meu-056826	Macropus eugenii	85.06	3.00e-73	269.00
IUUC-Mga-059827	Meleagris gallopavo	91.46	0.00e+00	730.00
IUUC-Mmr-060734	Microcebus murinus	97.98	0.00e+00	877.00
IUUC-Mdo-062988	Monodelphis domestica	94.61	0.00e+00	860.00
IUUC-Mmu-064415	Mus musculus	96.18	0.00e+00	805.00
IUUC-Mpu-066118	Mustela putorius furo	96.05	0.00e+00	719.00
IUUC-Mlu-067131	Myotis lucifugus	94.83	0.00e+00	829.00
IUUC-Nle-070112	Nomascus leucogenys	98.43	0.00e+00	858.00
IUUC-Opr-071193	Ochotona princeps	93.17	0.00e+00	793.00
IUUC-Ont-072635	Oreochromis niloticus	74.50	0.00e+00	646.00
IUUC-Oan-073266	Ornithorhynchus anatinus	90.14	0.00e+00	754.00
IUUC-Ocu-074903	Oryctolagus cuniculus	93.93	0.00e+00	839.00
IUUC-Ola-087533	Oryzias latipes	71.82	7.00e-177	613.00
IUUC-Oar-089747	Ovis aries	94.23	0.00e+00	780.00
IUUC-Ptr-090732	Pan troglodytes	98.43	0.00e+00	860.00
IUUC-Pan-092032	Papio anubis	98.20	0.00e+00	857.00
IUUC-Psi-093296	Pelodiscus sinensis	90.93	0.00e+00	784.00
IUUC-Pma-094351	Petromyzon marinus	51.40	7.00e-33	133.00
IUUC-Pfo-097183	Poecilia formosa	73.97	4.00e-175	607.00
IUUC-Pab-098177	Pongo abelii	97.98	0.00e+00	857.00
IUUC-Pca-100734	Procavia capensis	92.58	0.00e+00	830.00
IUUC-Pva-102778	Pteropus vampyrus	96.15	0.00e+00	818.00
IUUC-Rno-106039	Rattus norvegicus	95.96	0.00e+00	837.00
IUUC-Sha-106869	Sarcophilus harrisii	93.99	0.00e+00	800.00
IUUC-Sar-113587	Sorex araneus	65.14	1.00e-148	519.00
IUUC-Ssc-116212	Sus scrofa	95.51	0.00e+00	837.00
IUUC-Tgu-116871	Taeniopygia guttata	91.61	0.00e+00	758.00
IUUC-Tru-117925	Takifugu rubripes	73.21	0.00e+00	675.00
IUUC-Tsy-118815	Tarsius syrichta	95.43	0.00e+00	793.00
IUUC-Tni-120007	Tetraodon nigroviridis	73.65	0.00e+00	642.00
IUUC-Tbe-127381	Tupaia belangeri	93.18	0.00e+00	662.00
IUUC-Ttr-129025	Tursiops truncatus	80.53	0.00e+00	645.00
IUUC-Vpa-130164	Vicugna pacos	92.12	2.00e-149	521.00
IUUC-Xtr-132800	Xenopus tropicalis	82.47	0.00e+00	742.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence