iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Dre-028264

Ensembl Protein ID

ENSDARP00000045244.4

UniProt Accession

Q4VBS0; Q4VBS0_DANRE

Genbank Protein ID

AAH95338.1; AAI65444.1

Protein Name

Inhibitor of growth protein

Genbank Nucleotide ID

CR388038; BC165444

Gene Name

ing4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSDARG00000030716.4	ENSDART00000045245.4	ENSDARP00000045244.4

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	1.40e-09	38.9	198	245

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedekslveCek..Cr.ewfHpaClklsveeelpnsekwiCpkCrs 53
           ++C +C++ + +e  ++ C++  C+ ewfH+aC++l+   ++p+ + w+Cp+C++
   Q: 198  TYC-LCHQVSYGE--MIGCDNtdCSiEWFHFACVGLT---TKPRGK-WYCPRCSQ 245
           69*.*******99..*****999999***********...899996.******97 PP

Organism

Danio rerio

Protein Sequence
(Fasta)

MAAGMYLEHY LDSIENLPFE LQRNFQLMRD LDQRTEDLKG QIDSLAREYT ANARTLSSEQ 60
KLSLLRQIQQ SYGKCKEFGD DKVQLAMQTY EMVDKHIRRL DTDLARFEAD LKEKQIESTD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGAAGAACCT TTGTTTGTGT TTGTCAAGAT GGCGGCTGGA ATGTATCTAG AGCACTATTT 60
GGACAGTAAG ACTATTGTCT TCATTTTGAT ATTTATCCCC ACAAATAAAC ATCGTCCGTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0156--Chromatin regulator
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR028647--ING4
IPR028651--ING_fam
IPR024610--ING_N_histone_binding
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF12998--ING

SMART

SM01408--ING
SM00249--PHD

Gene Ontology

GO:0005634--C:nucleus
GO:0008270--F:zinc ion binding
GO:0016573--P:histone acetylation
GO:0008285--P:negative regulation of cell proliferation
GO:0043065--P:positive regulation of apoptotic process

KEGG

dre:322113

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001338	Ailuropoda melanoleuca	79.28	8.00e-107	379.00
IUUC-Apl-004097	Anas platyrhynchos	79.60	6.00e-108	383.00
IUUC-Aca-004593	Anolis carolinensis	82.87	8.00e-114	402.00
IUUC-Ame-011133	Astyanax mexicanus	95.60	8.00e-145	505.00
IUUC-Bta-012699	Bos taurus	79.28	4.00e-108	384.00
IUUC-Cja-019988	Callithrix jacchus	81.27	8.00e-102	363.00
IUUC-Cfa-021282	Canis familiaris	81.27	1.00e-101	362.00
IUUC-Cpo-022011	Cavia porcellus	81.67	2.00e-110	391.00
IUUC-Csa-023203	Chlorocebus sabaeus	81.27	8.00e-102	363.00
IUUC-Cin-025479	Ciona intestinalis	60.67	1.00e-80	292.00
IUUC-Csv-026288	Ciona savignyi	54.31	3.00e-76	278.00
IUUC-Dno-029766	Dasypus novemcinctus	78.00	1.00e-94	339.00
IUUC-Dor-031136	Dipodomys ordii	70.17	2.00e-82	298.00
IUUC-Eca-033565	Equus caballus	81.27	9.00e-110	389.00
IUUC-Eeu-034948	Erinaceus europaeus	69.76	3.00e-90	324.00
IUUC-Fca-036368	Felis catus	81.27	7.00e-102	363.00
IUUC-Fal-037120	Ficedula albicollis	79.20	9.00e-107	379.00
IUUC-Gmo-038982	Gadus morhua	88.05	6.00e-131	459.00
IUUC-Gga-040771	Gallus gallus	82.87	8.00e-114	402.00
IUUC-Gac-042184	Gasterosteus aculeatus	87.80	1.00e-128	451.00
IUUC-Ggo-045559	Gorilla gorilla	81.27	8.00e-102	363.00
IUUC-Hsa-046852	Homo sapiens	81.27	8.00e-102	363.00
IUUC-Itr-047978	Ictidomys tridecemlineatus	81.67	4.00e-110	390.00
IUUC-Loc-052334	Lepisosteus oculatus	73.12	4.00e-105	374.00
IUUC-Laf-054057	Loxodonta africana	81.27	7.00e-102	363.00
IUUC-Mcc-055212	Macaca mulatta	78.49	9.00e-102	362.00
IUUC-Meu-056511	Macropus eugenii	79.83	2.00e-100	358.00
IUUC-Mga-059967	Meleagris gallopavo	80.32	4.00e-107	380.00
IUUC-Mmr-060843	Microcebus murinus	80.48	3.00e-107	380.00
IUUC-Mdo-062357	Monodelphis domestica	80.48	6.00e-109	386.00
IUUC-Mmu-064093	Mus musculus	81.67	2.00e-110	391.00
IUUC-Mpu-066923	Mustela putorius furo	70.52	5.00e-80	290.00
IUUC-Mlu-067754	Myotis lucifugus	79.13	2.00e-108	385.00
IUUC-Nle-069062	Nomascus leucogenys	81.27	8.00e-102	363.00
IUUC-Opr-070207	Ochotona princeps	76.05	2.00e-94	338.00
IUUC-Ont-072446	Oreochromis niloticus	88.40	3.00e-123	434.00
IUUC-Ocu-074235	Oryctolagus cuniculus	81.27	8.00e-102	363.00
IUUC-Ola-086429	Oryzias latipes	84.40	2.00e-123	434.00
IUUC-Oga-089123	Otolemur garnettii	81.27	7.00e-102	363.00
IUUC-Oar-089524	Ovis aries	79.28	4.00e-108	384.00
IUUC-Ptr-090908	Pan troglodytes	81.27	7.00e-102	363.00
IUUC-Pan-092837	Papio anubis	79.28	9.00e-107	379.00
IUUC-Psi-093828	Pelodiscus sinensis	81.70	6.00e-103	366.00
IUUC-Ppa-096009	Physcomitrella patens	35.43	3.00e-36	145.00
IUUC-Pfo-096617	Poecilia formosa	88.00	4.00e-131	460.00
IUUC-Pab-097978	Pongo abelii	79.83	5.00e-91	327.00
IUUC-Pca-100475	Procavia capensis	54.00	5.00e-72	264.00
IUUC-Ppe-101441	Prunus persica	35.02	6.00e-38	150.00
IUUC-Pva-102325	Pteropus vampyrus	81.27	9.00e-110	389.00
IUUC-Rno-105178	Rattus norvegicus	81.67	1.00e-116	412.00
IUUC-Sha-106773	Sarcophilus harrisii	80.48	6.00e-109	387.00
IUUC-Sre-115124	Sporisorium reilianum	59.32	8.00e-22	99.00
IUUC-Ssc-115797	Sus scrofa	76.52	1.00e-90	325.00
IUUC-Tgu-117270	Taeniopygia guttata	82.87	8.00e-114	402.00
IUUC-Tru-118253	Takifugu rubripes	87.70	4.00e-131	460.00
IUUC-Tbe-127558	Tupaia belangeri	79.28	8.00e-107	379.00
IUUC-Ttr-128300	Tursiops truncatus	80.73	6.00e-51	194.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence