iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mpu-065974

Ensembl Protein ID

ENSMPUP00000012978.1

UniProt Accession

M3YNS1; M3YNS1_MUSPF

Genbank Protein ID

ENSMPUP00000012978

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEYP01006122

Gene Name

CUL9

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMPUG00000013074.1	ENSMPUT00000013187.1	ENSMPUP00000012978.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/Cullin	1.50e-130	436.8	1300	1819

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/Cullin

   S: 66   LktynreWekfreqlkvlrkifayldrtyvkkskkvsevrkLaldlwrkeivedikkrllelllklieaeRkgeavdrrllsgvves 152
           L    ++W+ freql++ +++f      y+ +           +++w+++i+ed +krll+l+ +l++ +R+++++++r+l++++++
   Q: 1300 LGPKPTFWPLFREQLCRRTCLF------YTIR-----------AQAWSRDIAED-RKRLLQLCPRLNRVLRHEQNFADRFLPDDEAA 1368
           5555689***************......9999...........***********.******************************** PP
   S: 153  lveLslnklaiykesFEakfleatqefykaesaeflqe.nevdeYlkkvearlneeeeraaryleestetkLlevvekeliakhles 238
                   +a++k+++Ea++++ +q++++++ + +++  + +d+Yl++++++  + +++a ++++++++++Ll++ve+   +     
   Q: 1369 --------QALGKTCWEALVSPLVQNITSPDTEGVSSLgWLLDQYLEQRQSSQDPLSRAAPFASRVRRLCHLLVHVEPPPEP----- 1442
           ........**************************************************************************..... PP
   S: 239  llaelvallrdkktedlsrmykLlsrvln..gleellkeleshikeqgkaaltaeekekdpkkyVerllelknklqklvseaFnnda 323
             ++ +++   +k+++ ++ +   s  l+  +l+++++++ s+++ q++++l+a++++ d   +V+r+++l+++lq++ se+F+++a
   Q: 1443 --SPEPSTRSISKNSKTRDRSPGPSAALPssSLRNITQCWLSVVQGQVSRFLAAAWRAPD---FVPRYCKLYEHLQRAGSELFGPRA 1524
           ..9***********************99999*****************************...************************ PP
   S: 324  kFlkaldkafetfvnknsvlkaakspEllAryiDqlLrks.skglteeeleaqldkvllvfkyisekdv...FekyYkkhLakRLls 406
           +F+ al+++f+ +++++s+l+aa+ +E++Ar+iDq+++++ ++g+ + e++ +l+++l+ ++++s++++   Fe++Y++++a+RLls
   Q: 1525 AFTVALRSGFSGALLQQSFLTAAHISEQFARHIDQQIQGGlVGGAPGVEMLGRLQRHLEPIMVLSGLELattFEHFYQHYMADRLLS 1611
           *************************************************************************************** PP
   S: 407  gksasseaEesviekLkeecgaeftskL.erMfqdlkvSedlnrqFk.................................eekente 459
             + ss++E++v+e++    g++f+++L ++M+++l++Se+l+rqF+                                 +eke   
   Q: 1612 --VGSSWLEGAVLEQI----GLCFPNRLpQQMLRSLSTSEELQRQFHlfqlqrldqqlleqeneeeqgleeeeeeaeeeeAEKELFI 1692
           ..**************....*********************************************************999999999* PP
   S: 460  esesvelsvlvLsagaWpta..set..ekvsLPaelektiekfeefY........lekhsgRkLqWqhtlgraelkaelkkgkyelq 534
           e+ s+++s+lvLs+++Wp++  +    ++ +LP+e+++++++f++fY        l+++++R+LqW++ lgrael++    g ++l+
   Q: 1693 EDSSPTVSILVLSPRCWPVSpfCYLyhPRKCLPTEFCDALDRFSNFYsqsqnhpvLDMGPHRRLQWTW-LGRAELQF----GDQTLH 1774
           *******************99866566*****************************************.********....****** PP
   S: 535  VstfQmavLLafnnsekvsveelkkatelpeeeLrrtlqsLvssk 579
           Vst+Qm++LL+fn++e+vsve+l k ++l +e+L ++l +L+s +
   Q: 1775 VSTVQMWLLLYFNQTEEVSVETLLKNSDLTPELLLQALLPLTSDN 1819
           ******************************************976 PP

Organism

Mustela putorius furo

Protein Sequence
(Fasta)

MVGERRTGDL MVPLGPRLQA YPEELIRQRP GHDGHPEYLI RWSVLKCGEV GRVGVEEGKT 60
EHILMWLSAP EVYANCPMLL GERALSKGPQ HEPAGGSGSF PRDPGGLDDT AMGEMEADVR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCGCGCCCCG CGCGCAGCGG CGCGGCCACT ACGCATGCTC CACTCGCGCG TCCTTCCGCC 60
ACGCTCGGGT GTGGGCTGCT GGGGCCCCCG TAGAAGCCGG GCCGCGCCCG CCCTGGCCGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR004939--APC_su10/DOC_dom
IPR011989--ARM-like
IPR016024--ARM-type_fold
IPR016150--Casein_kin_II_reg-sub_b-sht
IPR021097--CPH_domain
IPR031222--CUL9
IPR016157--Cullin_CS
IPR016158--Cullin_homology
IPR001373--Cullin_N
IPR019559--Cullin_neddylation_domain
IPR008979--Galactose-bd-like
IPR002867--IBR_dom
IPR014722--Rib_L2_dom2
IPR011991--WHTH_DNA-bd_dom
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS01256--CULLIN_1
PS50069--CULLIN_2
PS51284--DOC
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF03256--ANAPC10
PF11515--Cul7
PF00888--Cullin
PF10557--Cullin_Nedd8
PF01485--IBR

SMART

SM01337--APC10
SM00884--Cullin_Nedd8
SM00647--IBR

Gene Ontology

GO:0031461--C:cullin-RING ubiquitin ligase complex
GO:0005829--C:cytosol
GO:0008270--F:zinc ion binding
GO:0000226--P:microtubule cytoskeleton organization
GO:0016567--P:protein ubiquitination
GO:0007088--P:regulation of mitotic nuclear division
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001405	Ailuropoda melanoleuca	96.05	0.00e+00	4553.00
IUUC-Apl-003458	Anas platyrhynchos	64.88	0.00e+00	761.00
IUUC-Aca-004815	Anolis carolinensis	54.73	0.00e+00	1581.00
IUUC-Ame-010611	Astyanax mexicanus	50.64	0.00e+00	2257.00
IUUC-Bta-012877	Bos taurus	89.43	0.00e+00	4133.00
IUUC-Cja-019255	Callithrix jacchus	90.54	0.00e+00	4205.00
IUUC-Cfa-020119	Canis familiaris	95.52	0.00e+00	4487.00
IUUC-Cpo-022473	Cavia porcellus	83.72	0.00e+00	3754.00
IUUC-Csa-024157	Chlorocebus sabaeus	91.17	0.00e+00	4198.00
IUUC-Cho-024879	Choloepus hoffmanni	85.94	0.00e+00	910.00
IUUC-Cin-025402	Ciona intestinalis	38.04	1.00e-105	378.00
IUUC-Dno-028904	Dasypus novemcinctus	88.73	0.00e+00	4128.00
IUUC-Dor-030112	Dipodomys ordii	87.27	0.00e+00	1317.00
IUUC-Ete-032516	Echinops telfairi	81.68	0.00e+00	1347.00
IUUC-Eca-034394	Equus caballus	91.95	0.00e+00	4216.00
IUUC-Eeu-035166	Erinaceus europaeus	88.83	0.00e+00	2162.00
IUUC-Fca-035740	Felis catus	94.65	0.00e+00	4417.00
IUUC-Fal-036672	Ficedula albicollis	51.23	0.00e+00	1527.00
IUUC-Gga-040154	Gallus gallus	60.76	0.00e+00	889.00
IUUC-Ggo-045570	Gorilla gorilla	90.97	0.00e+00	4163.00
IUUC-Hsa-046690	Homo sapiens	91.05	0.00e+00	4150.00
IUUC-Itr-048680	Ictidomys tridecemlineatus	89.91	0.00e+00	4241.00
IUUC-Loc-052706	Lepisosteus oculatus	55.04	0.00e+00	1808.00
IUUC-Mcc-055727	Macaca mulatta	91.17	0.00e+00	4231.00
IUUC-Meu-056074	Macropus eugenii	75.96	0.00e+00	1488.00
IUUC-Mga-059683	Meleagris gallopavo	53.55	1.00e-100	360.00
IUUC-Mmr-060869	Microcebus murinus	90.53	0.00e+00	4246.00
IUUC-Mdo-062902	Monodelphis domestica	74.14	0.00e+00	3311.00
IUUC-Mmu-063991	Mus musculus	84.60	0.00e+00	3912.00
IUUC-Nle-069292	Nomascus leucogenys	91.69	0.00e+00	2690.00
IUUC-Opr-071020	Ochotona princeps	86.04	0.00e+00	2127.00
IUUC-Ont-071953	Oreochromis niloticus	50.65	0.00e+00	2172.00
IUUC-Oan-073534	Ornithorhynchus anatinus	59.01	0.00e+00	2068.00
IUUC-Ocu-074244	Oryctolagus cuniculus	88.39	0.00e+00	4106.00
IUUC-Ola-087072	Oryzias latipes	51.41	0.00e+00	2217.00
IUUC-Oga-088310	Otolemur garnettii	87.77	0.00e+00	4160.00
IUUC-Oar-090174	Ovis aries	89.50	0.00e+00	4076.00
IUUC-Ptr-091410	Pan troglodytes	91.17	0.00e+00	4136.00
IUUC-Pan-091856	Papio anubis	91.39	0.00e+00	2678.00
IUUC-Pma-094192	Petromyzon marinus	45.67	0.00e+00	1403.00
IUUC-Pfo-096773	Poecilia formosa	55.19	0.00e+00	938.00
IUUC-Pab-098635	Pongo abelii	91.96	0.00e+00	2905.00
IUUC-Pca-100539	Procavia capensis	89.54	0.00e+00	1331.00
IUUC-Pva-102813	Pteropus vampyrus	87.80	0.00e+00	1685.00
IUUC-Rno-106105	Rattus norvegicus	84.93	0.00e+00	3935.00
IUUC-Sha-106896	Sarcophilus harrisii	76.43	0.00e+00	1147.00
IUUC-Ssl-108406	Sclerotinia sclerotiorum	26.83	9.00e-08	51.60
IUUC-Sar-113132	Sorex araneus	81.03	0.00e+00	1268.00
IUUC-Ssc-116000	Sus scrofa	91.43	0.00e+00	4226.00
IUUC-Tgu-116915	Taeniopygia guttata	62.73	1.00e-140	493.00
IUUC-Tru-118013	Takifugu rubripes	54.78	0.00e+00	1539.00
IUUC-Tsy-119037	Tarsius syrichta	80.21	0.00e+00	1097.00
IUUC-Tni-120062	Tetraodon nigroviridis	51.20	0.00e+00	2253.00
IUUC-Ttr-128780	Tursiops truncatus	88.75	0.00e+00	2716.00
IUUC-Vpa-130086	Vicugna pacos	87.37	0.00e+00	673.00
IUUC-Xtr-132882	Xenopus tropicalis	50.58	0.00e+00	1831.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence