iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
DNA & RNA Element
microRNA	RAID2
Protein-protein Interaction
IID	iRefIndex	PINA	Mentha
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
ULD/UDP/UBQ/UBQ_PIM	29.76	1.00e-32	137.00	IUUC-Bta-013014
ULD/UDP/UBQ/UBQ_PIM	31.72	9.00e-41	164.00	IUUC-Gga-040353
ULD/UDP/UBQ/UBQ_PIM	30.48	1.00e-46	184.00	IUUC-Dme-031980
E3 activity/RBR	28.73	4.00e-43	173.00	IUUC-Hsa-046016
ULD/UDP/UBQ/UBQ_PIM	28.73	4.00e-43	173.00	IUUC-Hsa-046016
ULD/UDP/UBQ/UBQ_PIM	27.44	7.00e-42	168.00	IUUC-Mmu-063561
ULD/UDP/UBQ/UBQ_PIM	26.14	2.00e-16	84.00	IUUC-Rno-105556

Active Site

Position(s)	Description	Evidence
355	N/A	{ECO:0000256\|PIRSR:PIRSR037880-1}

Organism

Caenorhabditis elegans

Protein Sequence
(Fasta)

MSDEISILIQ DRKTGQRRNL TLNINITGNI EDLTKDVEKL TEIPSDELEV VFCGKKLSKS 60
TIMRDLSLTP ATQIMLLRPK FNSHNENGAT TAKITTDSSI LGSFYVWCKN CDDVKRGKLR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTAATGTTTA AAACTGCAAG CAGGCCCGCT AGCAGGAAAT TTTTTTGTTA ATTTCTAAGT 60
CAAATTTTCA GCTCTCATGA AGCATGTCTG ATGAAATCTC TATATTAATA CAAGATAGAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0677--Repeat
KW-0808--Transferase
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR016150--Casein_kin_II_reg-sub_b-sht
IPR031127--E3_UB_ligase_RBR
IPR002867--IBR_dom
IPR003977--Parkin
IPR029071--Ubiquitin-rel_dom
IPR000626--Ubiquitin_dom

PROSITE

PS50053--UBIQUITIN_2

Pfam

PF01485--IBR

PRINTS

PR01475--PARKIN

SMART

SM00647--IBR

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005829--C:cytosol
GO:0005741--C:mitochondrial outer membrane
GO:0043025--C:neuronal cell body
GO:0000151--C:ubiquitin ligase complex
GO:0046872--F:metal ion binding
GO:0031624--F:ubiquitin conjugating enzyme binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008340--P:determination of adult lifespan
GO:0000422--P:mitophagy
GO:0030336--P:negative regulation of cell migration
GO:1901075--P:negative regulation of engulfment of apoptotic cell
GO:0032436--P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0051865--P:protein autoubiquitination
GO:0000209--P:protein polyubiquitination
GO:0016567--P:protein ubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0009636--P:response to toxic substance

KEGG

cel:CELE_K08E3.7

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001814	Ailuropoda melanoleuca	24.82	5.00e-18	83.60
IUUC-Apl-003304	Anas platyrhynchos	31.61	5.00e-41	159.00
IUUC-Aca-004908	Anolis carolinensis	42.62	2.00e-12	62.80
IUUC-Ame-011856	Astyanax mexicanus	28.29	6.00e-47	180.00
IUUC-Bta-013014	Bos taurus	24.24	1.00e-28	119.00
IUUC-Cja-019579	Callithrix jacchus	34.07	2.00e-23	100.00
IUUC-Cfa-020461	Canis familiaris	24.19	8.00e-16	76.30
IUUC-Cpo-022251	Cavia porcellus	25.82	1.00e-18	85.10
IUUC-Csa-023112	Chlorocebus sabaeus	25.82	2.00e-18	85.10
IUUC-Cho-024504	Choloepus hoffmanni	27.27	6.00e-17	80.90
IUUC-Dre-028202	Danio rerio	26.89	5.00e-40	157.00
IUUC-Dno-028946	Dasypus novemcinctus	44.26	1.00e-13	66.60
IUUC-Dor-030508	Dipodomys ordii	22.39	9.00e-16	76.30
IUUC-Dme-031980	Drosophila melanogaster	30.02	3.00e-51	194.00
IUUC-Ete-032281	Echinops telfairi	27.59	6.00e-09	54.30
IUUC-Eca-033228	Equus caballus	25.36	2.00e-18	84.70
IUUC-Fal-037507	Ficedula albicollis	27.25	2.00e-44	172.00
IUUC-Gmo-038744	Gadus morhua	29.96	4.00e-28	117.00
IUUC-Gga-040353	Gallus gallus	26.75	1.00e-42	166.00
IUUC-Gac-042519	Gasterosteus aculeatus	29.47	3.00e-40	158.00
IUUC-Hsa-046016	Homo sapiens	28.07	4.00e-45	174.00
IUUC-Itr-048744	Ictidomys tridecemlineatus	25.44	3.00e-36	144.00
IUUC-Loc-052389	Lepisosteus oculatus	27.25	9.00e-41	159.00
IUUC-Mcc-054933	Macaca mulatta	29.22	1.00e-45	176.00
IUUC-Meu-055963	Macropus eugenii	23.53	6.00e-16	77.00
IUUC-Mmr-061566	Microcebus murinus	29.82	6.00e-21	92.80
IUUC-Mdo-061952	Monodelphis domestica	44.83	6.00e-13	63.50
IUUC-Mmu-063561	Mus musculus	26.59	7.00e-44	170.00
IUUC-Mpu-065799	Mustela putorius furo	25.09	9.00e-17	79.30
IUUC-Mlu-068134	Myotis lucifugus	25.08	4.00e-24	103.00
IUUC-Nle-070078	Nomascus leucogenys	26.43	1.00e-18	85.90
IUUC-Opr-070541	Ochotona princeps	27.41	1.00e-40	159.00
IUUC-Ont-071743	Oreochromis niloticus	26.08	2.00e-40	159.00
IUUC-Ola-086426	Oryzias latipes	32.35	2.00e-22	96.70
IUUC-Oga-088867	Otolemur garnettii	27.75	7.00e-46	176.00
IUUC-Oar-089365	Ovis aries	25.97	2.00e-26	112.00
IUUC-Ptr-091371	Pan troglodytes	28.07	5.00e-45	174.00
IUUC-Pan-092443	Papio anubis	26.49	2.00e-18	84.70
IUUC-Psi-093851	Pelodiscus sinensis	27.98	4.00e-18	83.60
IUUC-Pfo-097194	Poecilia formosa	26.44	5.00e-44	170.00
IUUC-Pab-097999	Pongo abelii	21.32	5.00e-16	77.00
IUUC-Pca-100410	Procavia capensis	25.73	6.00e-26	110.00
IUUC-Pva-102300	Pteropus vampyrus	24.00	2.00e-27	115.00
IUUC-Rno-105556	Rattus norvegicus	25.45	2.00e-18	84.70
IUUC-Ssc-116435	Sus scrofa	26.37	3.00e-19	87.80
IUUC-Tgu-117489	Taeniopygia guttata	27.47	1.00e-42	166.00
IUUC-Tru-117927	Takifugu rubripes	32.29	3.00e-42	164.00
IUUC-Tsy-119372	Tarsius syrichta	32.21	2.00e-40	159.00
IUUC-Tni-120043	Tetraodon nigroviridis	31.03	1.00e-40	159.00
IUUC-Tbe-127539	Tupaia belangeri	24.50	7.00e-34	136.00
IUUC-Ttr-129149	Tursiops truncatus	26.65	2.00e-44	171.00
IUUC-Vpa-130439	Vicugna pacos	24.34	1.00e-24	106.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence