iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Fca-036460

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AANG02117226

Gene Name

STUB1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFCAG00000008311.2	ENSFCAT00000008313.2	ENSFCAP00000007706.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/U-box	8.60e-27	93.0	223	296

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/U-box

   S: 1    evpeeflCpIslelMrdPvvlpsGitydrssIekwlasggktcPvtrqplteedlvPnltlrrliqawceenss 74
           ++p+++++ Is+elMr+P+++psGitydr+ Ie++l++ g+ +Pvtr+plt+e+l+Pnl+++++i+a+++en++
   Q: 223  DIPDYLCGKISFELMREPCITPSGITYDRKDIEEHLQRVGHFDPVTRSPLTQEQLIPNLAMKEVIDAFISENGW 296
           69********************************************************************9986 PP

Organism

Felis catus

Protein Sequence
(Fasta)

GQIGLGVTGG GPHPGGPPPR REAPPHTWQG NRLFVGRKYP EAAACYGRAI TRNPLVAVYY 60
TNRALCYLKM QQHEQALADC RRALELDGQS VKAHFFLGQC QLEMESYDEA IANLQRAYNL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGGCAGATCG GGTTGGGGGT CACGGGTGGT GGACCTCACC CGGGGGGCCC GCCCCCACGC 60
CGCGAGGCCC CGCCCCACAC GTGGGAAGCC CTCACCACCC GCTTGCACGC CGGCAGCCGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0802--TPR repeat

Interpro

IPR023114--Elongated_TPR_rpt_dom
IPR013026--TPR-contain_dom
IPR011990--TPR-like_helical_dom
IPR019734--TPR_repeat
IPR003613--Ubox_domain
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50005--TPR
PS50293--TPR_REGION
PS51698--U_BOX

Pfam

PF04564--U-box

SMART

SM00028--TPR
SM00504--Ubox

Gene Ontology

GO:0005829--C:cytosol
GO:0005783--C:endoplasmic reticulum
GO:0070062--C:extracellular exosome
GO:0042405--C:nuclear inclusion body
GO:0005654--C:nucleoplasm
GO:0000151--C:ubiquitin ligase complex
GO:0030018--C:Z disc
GO:1904264--F:ubiquitin protein ligase activity involved in ERAD pathway
GO:0034450--F:ubiquitin-ubiquitin ligase activity
GO:0071218--P:cellular response to misfolded protein
GO:0030968--P:endoplasmic reticulum unfolded protein response
GO:0006515--P:misfolded or incompletely synthesized protein catabolic process
GO:0032091--P:negative regulation of protein binding
GO:0030512--P:negative regulation of transforming growth factor beta receptor signaling pathway
GO:0090035--P:positive regulation of chaperone-mediated protein complex assembly
GO:0032436--P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0051443--P:positive regulation of ubiquitin-protein transferase activity
GO:0051865--P:protein autoubiquitination
GO:0070534--P:protein K63-linked ubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0031943--P:regulation of glucocorticoid metabolic process
GO:0031647--P:regulation of protein stability
GO:0030579--P:ubiquitin-dependent SMAD protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000537	Aegilops tauschii	36.90	1.00e-38	152.00
IUUC-Aml-001350	Ailuropoda melanoleuca	99.60	7.00e-148	515.00
IUUC-Atr-003168	Amborella trichopoda	33.64	9.00e-31	126.00
IUUC-Apl-003736	Anas platyrhynchos	89.24	2.00e-133	467.00
IUUC-Aca-004751	Anolis carolinensis	88.28	2.00e-142	498.00
IUUC-Aly-006292	Arabidopsis lyrata	33.82	1.00e-41	163.00
IUUC-Ath-007012	Arabidopsis thaliana	33.95	6.00e-41	160.00
IUUC-Acl-008025	Aspergillus clavatus	30.94	7.00e-35	140.00
IUUC-Afl-008721	Aspergillus flavus	30.63	3.00e-31	128.00
IUUC-Afu-008853	Aspergillus fumigatus	31.91	4.00e-34	138.00
IUUC-Ani-009349	Aspergillus nidulans	31.01	1.00e-33	136.00
IUUC-Ang-009674	Aspergillus niger	32.27	1.00e-30	126.00
IUUC-Aor-010014	Aspergillus oryzae	30.19	6.00e-28	117.00
IUUC-Ate-010467	Aspergillus terreus	28.32	1.00e-24	106.00
IUUC-Ame-011215	Astyanax mexicanus	60.29	4.00e-89	320.00
IUUC-Bgr-011971	Blumeria graminis	30.22	3.00e-24	105.00
IUUC-Bta-013025	Bos taurus	99.63	6.00e-161	559.00
IUUC-Bci-013945	Botrytis cinerea	39.51	1.00e-14	73.90
IUUC-Bdi-014483	Brachypodium distachyon	37.63	4.00e-44	171.00
IUUC-Bol-015676	Brassica oleracea	34.94	1.00e-43	170.00
IUUC-Bra-017897	Brassica rapa	32.06	1.00e-29	123.00
IUUC-Cel-018323	Caenorhabditis elegans	41.03	4.00e-55	207.00
IUUC-Cja-019657	Callithrix jacchus	96.69	1.00e-159	555.00
IUUC-Cfa-020470	Canis familiaris	99.13	2.00e-135	474.00
IUUC-Cpo-022033	Cavia porcellus	97.43	2.00e-159	554.00
IUUC-Cre-022896	Chlamydomonas reinhardtii	27.56	6.00e-27	114.00
IUUC-Csa-023038	Chlorocebus sabaeus	97.79	6.00e-153	533.00
IUUC-Cin-025381	Ciona intestinalis	52.88	2.00e-87	315.00
IUUC-Cgl-026524	Colletotrichum gloeosporioides	32.00	6.00e-38	150.00
IUUC-Dre-027610	Danio rerio	80.15	2.00e-131	461.00
IUUC-Dno-030087	Dasypus novemcinctus	98.16	3.00e-161	560.00
IUUC-Dor-031029	Dipodomys ordii	91.18	5.00e-143	499.00
IUUC-Dse-031275	Dothistroma septosporum	31.12	3.00e-26	112.00
IUUC-Dme-031856	Drosophila melanogaster	57.72	1.00e-92	332.00
IUUC-Ete-033087	Echinops telfairi	94.19	2.00e-134	471.00
IUUC-Eca-033512	Equus caballus	98.40	1.00e-146	511.00
IUUC-Eeu-034763	Erinaceus europaeus	93.48	5.00e-99	352.00
IUUC-Fal-037441	Ficedula albicollis	88.53	8.00e-147	512.00
IUUC-Fox-038028	Fusarium oxysporum	30.45	5.00e-37	147.00
IUUC-Fso-038323	Fusarium solani	31.88	2.00e-27	115.00
IUUC-Gmo-038511	Gadus morhua	77.94	8.00e-127	446.00
IUUC-Ggr-039964	Gaeumannomyces graminis	32.98	2.00e-26	112.00
IUUC-Gga-040854	Gallus gallus	88.53	6.00e-146	509.00
IUUC-Gac-042175	Gasterosteus aculeatus	77.57	3.00e-123	434.00
IUUC-Gma-044046	Glycine max	36.30	3.00e-42	165.00
IUUC-Ggo-044512	Gorilla gorilla	97.79	6.00e-153	533.00
IUUC-Hsa-046872	Homo sapiens	97.79	6.00e-153	533.00
IUUC-Hvu-047661	Hordeum vulgare	35.61	2.00e-39	155.00
IUUC-Itr-048871	Ictidomys tridecemlineatus	96.69	8.00e-159	552.00
IUUC-Lch-049988	Latimeria chalumnae	80.59	3.00e-128	451.00
IUUC-Lpe-050693	Leersia perrieri	34.41	7.00e-42	163.00
IUUC-Loc-052195	Lepisosteus oculatus	79.61	5.00e-117	413.00
IUUC-Lma-053207	Leptosphaeria maculans	30.10	7.00e-28	119.00
IUUC-Laf-054584	Loxodonta africana	97.06	3.00e-160	557.00
IUUC-Mcc-054689	Macaca mulatta	97.79	6.00e-153	533.00
IUUC-Meu-055998	Macropus eugenii	91.61	9.00e-77	280.00
IUUC-Mor-057116	Magnaporthe oryzae	32.97	1.00e-37	149.00
IUUC-Mtr-057684	Medicago truncatula	33.58	1.00e-37	149.00
IUUC-Mga-059332	Meleagris gallopavo	89.64	6.00e-133	466.00
IUUC-Mmr-061377	Microcebus murinus	97.06	2.00e-151	527.00
IUUC-Mdo-061963	Monodelphis domestica	92.31	2.00e-141	494.00
IUUC-Mmu-063146	Mus musculus	97.43	6.00e-151	526.00
IUUC-Mac-064932	Musa acuminata	34.47	3.00e-28	117.00
IUUC-Mpu-066418	Mustela putorius furo	99.63	6.00e-162	562.00
IUUC-Mlu-067066	Myotis lucifugus	98.90	5.00e-162	563.00
IUUC-Nfi-068601	Neosartorya fischeri	31.91	6.00e-34	137.00
IUUC-Ncr-068761	Neurospora crassa	41.67	4.00e-17	81.60
IUUC-Nle-069374	Nomascus leucogenys	97.79	6.00e-153	533.00
IUUC-Opr-070765	Ochotona princeps	90.71	2.00e-100	357.00
IUUC-Ont-071996	Oreochromis niloticus	80.88	7.00e-126	442.00
IUUC-Oba-075967	Oryza barthii	35.79	6.00e-43	167.00
IUUC-Obr-076440	Oryza brachyantha	34.98	9.00e-32	132.00
IUUC-Ogl-076959	Oryza glaberrima	35.94	1.00e-43	169.00
IUUC-Ogu-078247	Oryza glumaepatula	36.07	2.00e-40	159.00
IUUC-Oin-079616	Oryza indica	35.94	1.00e-43	169.00
IUUC-Olo-081083	Oryza longistaminata	30.82	5.00e-30	124.00
IUUC-Ome-081935	Oryza meridionalis	29.06	3.00e-21	97.80
IUUC-Oni-082535	Oryza nivara	36.07	2.00e-40	159.00
IUUC-Opu-083794	Oryza punctata	35.36	2.00e-42	166.00
IUUC-Oru-085153	Oryza rufipogon	35.79	1.00e-42	166.00
IUUC-Osa-085936	Oryza sativa	34.04	2.00e-15	75.50
IUUC-Ola-087081	Oryzias latipes	79.41	1.00e-129	455.00
IUUC-Olu-087790	Ostreococcus lucimarinus	31.14	5.00e-30	124.00
IUUC-Oga-088331	Otolemur garnettii	97.43	1.00e-152	531.00
IUUC-Oar-089987	Ovis aries	90.07	1.00e-143	502.00
IUUC-Ptr-090855	Pan troglodytes	97.79	6.00e-153	533.00
IUUC-Pan-092801	Papio anubis	91.91	6.00e-151	526.00
IUUC-Psi-093393	Pelodiscus sinensis	88.45	2.00e-132	464.00
IUUC-Pma-094680	Petromyzon marinus	68.50	2.00e-109	388.00
IUUC-Pno-094913	Phaeosphaeria nodorum	33.57	8.00e-33	133.00
IUUC-Ppa-095976	Physcomitrella patens	33.33	1.00e-41	163.00
IUUC-Pfo-096850	Poecilia formosa	78.68	2.00e-122	431.00
IUUC-Pab-097963	Pongo abelii	97.79	6.00e-153	533.00
IUUC-Pop-098805	Populus trichocarpa	43.88	9.00e-25	106.00
IUUC-Pca-100788	Procavia capensis	97.43	4.00e-161	560.00
IUUC-Ppe-101221	Prunus persica	34.44	1.00e-42	166.00
IUUC-Pva-103076	Pteropus vampyrus	98.90	2.00e-161	560.00
IUUC-Pte-104237	Pyrenophora teres	31.87	4.00e-32	131.00
IUUC-Pyt-104468	Pyrenophora triticirepentis	31.87	3.00e-32	132.00
IUUC-Rno-105204	Rattus norvegicus	97.43	3.00e-151	527.00
IUUC-Sha-106579	Sarcophilus harrisii	87.11	3.00e-128	450.00
IUUC-Smo-109525	Selaginella moellendorffii	35.45	2.00e-40	158.00
IUUC-Sit-110665	Setaria italica	35.00	3.00e-43	168.00
IUUC-Sly-111473	Solanum lycopersicum	37.36	2.00e-43	169.00
IUUC-Stu-112353	Solanum tuberosum	36.16	2.00e-41	162.00
IUUC-Sbi-114250	Sorghum bicolor	37.04	1.00e-43	169.00
IUUC-Ssc-115416	Sus scrofa	98.90	2.00e-161	561.00
IUUC-Tgu-117272	Taeniopygia guttata	94.44	7.00e-57	211.00
IUUC-Tru-117777	Takifugu rubripes	79.78	3.00e-124	437.00
IUUC-Tni-120572	Tetraodon nigroviridis	81.25	3.00e-125	441.00
IUUC-Tca-121149	Theobroma cacao	38.89	4.00e-48	184.00
IUUC-Tre-122230	Trichoderma reesei	31.99	1.00e-30	126.00
IUUC-Tvi-122678	Trichoderma virens	35.04	3.00e-40	158.00
IUUC-Tae-122986	Triticum aestivum	35.79	7.00e-42	163.00
IUUC-Tur-126009	Triticum urartu	34.30	1.00e-37	150.00
IUUC-Tme-126948	Tuber melanosporum	35.27	4.00e-39	154.00
IUUC-Ttr-129031	Tursiops truncatus	98.90	3.00e-161	560.00
IUUC-Vda-130023	Verticillium dahliae	32.23	7.00e-38	150.00
IUUC-Vvi-131091	Vitis vinifera	40.80	6.00e-25	106.00
IUUC-Xtr-132871	Xenopus tropicalis	83.88	5.00e-127	446.00
IUUC-Xma-134220	Xiphophorus maculatus	79.04	8.00e-123	432.00
IUUC-Yli-134462	Yarrowia lipolytica	28.47	2.00e-26	112.00
IUUC-Zma-135773	Zea mays	36.00	3.00e-44	171.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence