iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Psi-093484

Ensembl Protein ID

ENSPSIP00000005780.1

UniProt Accession

K7FCM0; K7FCM0_PELSI

Genbank Protein ID

ENSPSIP00000005780

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGCU01075885

Gene Name

KLHL22

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPSIG00000005376.1	ENSPSIT00000005814.1	ENSPSIP00000005780.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_Other: BTB	1.10e-18	67.3	51	115

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_Other: BTB

   S: 2    DvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgklde 67
           Dv+lvv+g+ ++ah+i Laas+++F+ +f ++l+e+  +++v+i++v++ ++  +l+F+Yt++l++
   Q: 51   DVVLVVEGKPIEAHRILLAASCDYFRGMFAGGLREMG-QEEVHIHGVSYNAMCKILSFIYTSELEL 115
           9***********************************9.*************************986 PP

Organism

Pelodiscus sinensis

Protein Sequence
(Fasta)

MAEDQELTQT CKTPWETSLQ QCSSHTYRSA QHSQSLLSGL VSLRDSGILF DVVLVVEGKP 60
IEAHRILLAA SCDYFRGMFA GGLREMGQEE VHIHGVSYNA MCKILSFIYT SELELSLNNV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNGGTGA 60
GACGCGGCTC GCTCCCTCAG CCGCCTGCAG GGGAAAGAAA CGGCAGGAGG CAGGTCTGGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR030575--KLHL22
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0005813--C:centrosome
GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0005737--C:cytoplasm
GO:0072686--C:mitotic spindle
GO:0005827--C:polar microtubule
GO:0051301--P:cell division
GO:0000070--P:mitotic sister chromatid segregation
GO:0007094--P:mitotic spindle assembly checkpoint
GO:0006513--P:protein monoubiquitination

KEGG

pss:102444744

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002097	Ailuropoda melanoleuca	78.68	0.00e+00	1041.00
IUUC-Apl-004081	Anas platyrhynchos	85.27	0.00e+00	1146.00
IUUC-Aca-005015	Anolis carolinensis	66.83	0.00e+00	884.00
IUUC-Ame-011712	Astyanax mexicanus	57.47	0.00e+00	744.00
IUUC-Bta-012594	Bos taurus	77.59	0.00e+00	1051.00
IUUC-Cja-019752	Callithrix jacchus	78.39	0.00e+00	860.00
IUUC-Cfa-020884	Canis familiaris	79.00	0.00e+00	1069.00
IUUC-Cpo-021711	Cavia porcellus	78.84	0.00e+00	1066.00
IUUC-Csa-023211	Chlorocebus sabaeus	79.15	0.00e+00	1069.00
IUUC-Dre-028395	Danio rerio	59.55	0.00e+00	773.00
IUUC-Dno-030096	Dasypus novemcinctus	78.53	0.00e+00	1068.00
IUUC-Dor-030709	Dipodomys ordii	78.65	1.00e-175	609.00
IUUC-Dme-031924	Drosophila melanogaster	28.73	2.00e-56	213.00
IUUC-Eca-033388	Equus caballus	78.68	0.00e+00	1066.00
IUUC-Eeu-034616	Erinaceus europaeus	70.53	0.00e+00	945.00
IUUC-Fca-035815	Felis catus	79.00	0.00e+00	1068.00
IUUC-Fal-037311	Ficedula albicollis	86.18	0.00e+00	1095.00
IUUC-Gmo-039571	Gadus morhua	52.60	1.00e-162	566.00
IUUC-Gga-040992	Gallus gallus	85.42	0.00e+00	1148.00
IUUC-Gac-042041	Gasterosteus aculeatus	59.01	0.00e+00	703.00
IUUC-Ggo-045141	Gorilla gorilla	74.76	0.00e+00	1009.00
IUUC-Hsa-045984	Homo sapiens	79.15	0.00e+00	1071.00
IUUC-Itr-048890	Ictidomys tridecemlineatus	79.00	0.00e+00	1071.00
IUUC-Lch-049700	Latimeria chalumnae	62.50	0.00e+00	773.00
IUUC-Loc-052141	Lepisosteus oculatus	63.48	0.00e+00	857.00
IUUC-Laf-053487	Loxodonta africana	79.05	0.00e+00	1060.00
IUUC-Mcc-054682	Macaca mulatta	80.93	0.00e+00	881.00
IUUC-Meu-055937	Macropus eugenii	72.57	0.00e+00	967.00
IUUC-Mga-059953	Meleagris gallopavo	85.42	0.00e+00	1148.00
IUUC-Mmr-061743	Microcebus murinus	79.00	0.00e+00	1068.00
IUUC-Mdo-062328	Monodelphis domestica	79.15	0.00e+00	1063.00
IUUC-Mmu-063979	Mus musculus	77.81	0.00e+00	1042.00
IUUC-Mpu-066750	Mustela putorius furo	79.15	0.00e+00	1070.00
IUUC-Mlu-066960	Myotis lucifugus	78.68	0.00e+00	1063.00
IUUC-Nle-069690	Nomascus leucogenys	79.68	0.00e+00	955.00
IUUC-Opr-071059	Ochotona princeps	73.08	0.00e+00	972.00
IUUC-Ont-072004	Oreochromis niloticus	58.66	0.00e+00	706.00
IUUC-Oan-073172	Ornithorhynchus anatinus	63.08	0.00e+00	767.00
IUUC-Ocu-074310	Oryctolagus cuniculus	76.49	6.00e-127	446.00
IUUC-Ola-086599	Oryzias latipes	57.39	0.00e+00	710.00
IUUC-Oga-087980	Otolemur garnettii	78.53	0.00e+00	1061.00
IUUC-Oar-089956	Ovis aries	65.13	0.00e+00	775.00
IUUC-Ptr-090598	Pan troglodytes	79.75	0.00e+00	959.00
IUUC-Pan-092387	Papio anubis	81.13	0.00e+00	882.00
IUUC-Pma-094224	Petromyzon marinus	52.94	0.00e+00	637.00
IUUC-Pfo-096149	Poecilia formosa	59.14	0.00e+00	732.00
IUUC-Pab-098097	Pongo abelii	79.31	0.00e+00	1073.00
IUUC-Pca-100118	Procavia capensis	80.54	2.00e-178	619.00
IUUC-Pva-103174	Pteropus vampyrus	76.03	5.00e-126	444.00
IUUC-Rno-105350	Rattus norvegicus	78.48	0.00e+00	1019.00
IUUC-Sha-106817	Sarcophilus harrisii	80.15	8.00e-133	467.00
IUUC-Sar-113490	Sorex araneus	81.05	4.00e-166	577.00
IUUC-Ssc-115827	Sus scrofa	78.21	0.00e+00	1061.00
IUUC-Tgu-116748	Taeniopygia guttata	87.07	0.00e+00	966.00
IUUC-Tru-118644	Takifugu rubripes	56.13	0.00e+00	724.00
IUUC-Tsy-118888	Tarsius syrichta	73.84	0.00e+00	868.00
IUUC-Tni-120060	Tetraodon nigroviridis	53.75	7.00e-177	613.00
IUUC-Ttr-129183	Tursiops truncatus	78.83	0.00e+00	952.00
IUUC-Xtr-132780	Xenopus tropicalis	72.71	0.00e+00	972.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence