iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mdo-062453

UUCD1 version

UUC-MoD-00588

Ensembl Protein ID

ENSMODP00000013078.3

UniProt Accession

F6YTJ2; F6YTJ2_MONDO

Protein Name

Uncharacterized protein

Gene Name

RNF14

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000010433.3	ENSMODT00000013316.3	ENSMODP00000013078.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RBR	3.90e-54	184.2	220	433

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RBR

   S: 1    CkvCllelsveeltvlleCehtfCkeClkqylelkikegqvteiscpaaecpekleeseikellveeelykryekllleevveadaalkw 90
           C++C++e+  +e++++leC+h++Ck+Clk+y+e++i++gqv++++cp+++c++ +++ ++ke lveeel++ry++lll+++++ +a++ +
   Q: 220  CNICFCEKLGSECMYFLECRHVYCKACLKDYFEIQIRDGQVHCLNCPEPKCSSVATPGQVKE-LVEEELFARYDRLLLQSTLDLMADVVY 308
           **************************************************************.7************************** PP
   S: 91   cpapdCslvvllekeaekleve.cekcgkefCveCkeewHeglsCkelkeklakteeek........................eeaeske 155
           cp+p+C+++v++e+     ++  c++c+ +fC+ Ck ++H  + Ck ++ekl + ++e+                        ee+eske
   Q: 309  CPRPCCQTPVMQEPG---CTMGiCSSCNYAFCTLCKMTYHGVSPCKVTAEKLIDLRNEYlgadeankrfleqrygkrviqkalEEMESKE 395
           *************95...33337***********************************9******************************* PP
   S: 156  lleanskkCpkCkvyieknegCnhmtCakCkaefCwlC 193
           +le+nsk+Cp+C + iek +gCn+mtC+ C+++fCw+C
   Q: 396  WLEKNSKSCPCCGTHIEKLDGCNKMTCTGCMQYFCWIC 433
           ************************************** PP

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

MSSEDREAQE DELLALASIY DEDEFKKAES VQGGETRICL DLPQNFKIFV SGNPTECLQN 60
GGFEYTICFL PPLVLNFELP PDYPSTSPPA FTLSGKWLSP TQLTALCKHL DNLWEEHRGC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCATAAT TAAACCTATG ACTATACCTA TCTTAGATAA ATCCTTATGT ATTATCCTAT 60
AGACTCATTC TGGATCCTGT AATCTCACAT ACAAATCTCA CATTTGGTAA TGAAGGGTAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0677--Repeat
KW-0808--Transferase
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR016150--Casein_kin_II_reg-sub_b-sht
IPR031127--E3_UB_ligase_RBR
IPR002867--IBR_dom
IPR006575--RWD-domain
IPR016135--UBQ-conjugating_enzyme/RWD
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50908--RWD
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF01485--IBR
PF05773--RWD

SMART

SM00647--IBR
SM00591--RWD

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0000151--C:ubiquitin ligase complex
GO:0031624--F:ubiquitin conjugating enzyme binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0032436--P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0045893--P:positive regulation of transcription, DNA-templated
GO:0000209--P:protein polyubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0060765--P:regulation of androgen receptor signaling pathway
GO:0007165--P:signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001130	Aegilops tauschii	29.00	3.00e-56	213.00
IUUC-Aml-001458	Ailuropoda melanoleuca	90.83	0.00e+00	831.00
IUUC-Atr-002560	Amborella trichopoda	29.68	2.00e-49	190.00
IUUC-Apl-003680	Anas platyrhynchos	87.94	0.00e+00	823.00
IUUC-Aca-005000	Anolis carolinensis	75.44	0.00e+00	699.00
IUUC-Aly-006288	Arabidopsis lyrata	30.62	7.00e-59	221.00
IUUC-Ath-006719	Arabidopsis thaliana	30.80	8.00e-59	221.00
IUUC-Acl-008213	Aspergillus clavatus	24.44	4.00e-34	139.00
IUUC-Afl-008433	Aspergillus flavus	25.06	1.00e-34	141.00
IUUC-Afu-008772	Aspergillus fumigatus	25.71	2.00e-36	147.00
IUUC-Ani-009249	Aspergillus nidulans	25.52	5.00e-34	139.00
IUUC-Ang-009757	Aspergillus niger	28.14	2.00e-40	160.00
IUUC-Aor-009963	Aspergillus oryzae	24.67	8.00e-34	139.00
IUUC-Ate-010460	Aspergillus terreus	24.74	9.00e-35	141.00
IUUC-Ame-011312	Astyanax mexicanus	59.25	3.00e-151	528.00
IUUC-Bgr-012052	Blumeria graminis	22.60	4.00e-33	135.00
IUUC-Bta-013529	Bos taurus	89.91	0.00e+00	829.00
IUUC-Bci-013729	Botrytis cinerea	23.99	5.00e-31	129.00
IUUC-Bdi-014940	Brachypodium distachyon	30.95	9.00e-53	201.00
IUUC-Bra-016998	Brassica rapa	30.65	1.00e-56	214.00
IUUC-Cel-018547	Caenorhabditis elegans	31.42	1.00e-56	213.00
IUUC-Cja-019791	Callithrix jacchus	89.47	0.00e+00	830.00
IUUC-Cfa-020403	Canis familiaris	90.57	0.00e+00	835.00
IUUC-Cpo-022229	Cavia porcellus	87.34	0.00e+00	791.00
IUUC-Cre-022601	Chlamydomonas reinhardtii	34.42	8.00e-30	122.00
IUUC-Csa-024115	Chlorocebus sabaeus	90.35	0.00e+00	832.00
IUUC-Cho-024911	Choloepus hoffmanni	91.01	0.00e+00	840.00
IUUC-Cin-025578	Ciona intestinalis	42.24	9.00e-100	357.00
IUUC-Csv-026355	Ciona savignyi	40.57	4.00e-88	318.00
IUUC-Cgl-026439	Colletotrichum gloeosporioides	20.04	5.00e-28	119.00
IUUC-Cne-026782	Cryptococcus neoformans	23.40	2.00e-26	114.00
IUUC-Dre-027380	Danio rerio	58.46	3.00e-157	548.00
IUUC-Dno-029640	Dasypus novemcinctus	91.25	0.00e+00	837.00
IUUC-Dor-030681	Dipodomys ordii	89.91	0.00e+00	826.00
IUUC-Dse-031208	Dothistroma septosporum	23.61	3.00e-34	140.00
IUUC-Ete-033122	Echinops telfairi	62.38	6.00e-147	513.00
IUUC-Eca-033755	Equus caballus	89.47	0.00e+00	819.00
IUUC-Eeu-035034	Erinaceus europaeus	90.41	2.00e-67	249.00
IUUC-Fca-036461	Felis catus	90.57	0.00e+00	833.00
IUUC-Fal-037516	Ficedula albicollis	86.62	0.00e+00	823.00
IUUC-Fso-038307	Fusarium solani	22.00	7.00e-28	119.00
IUUC-Gmo-039563	Gadus morhua	58.81	2.00e-158	551.00
IUUC-Ggr-039920	Gaeumannomyces graminis	22.60	1.00e-25	111.00
IUUC-Gga-040331	Gallus gallus	85.75	0.00e+00	795.00
IUUC-Gac-042164	Gasterosteus aculeatus	59.04	2.00e-161	561.00
IUUC-Gma-044080	Glycine max	31.96	3.00e-64	239.00
IUUC-Ggo-045257	Gorilla gorilla	90.13	0.00e+00	833.00
IUUC-Hsa-046887	Homo sapiens	90.13	0.00e+00	832.00
IUUC-Hvu-047317	Hordeum vulgare	28.76	1.00e-45	177.00
IUUC-Itr-048199	Ictidomys tridecemlineatus	89.91	0.00e+00	829.00
IUUC-Lch-050155	Latimeria chalumnae	66.81	1.00e-172	598.00
IUUC-Lpe-051669	Leersia perrieri	26.28	2.00e-38	153.00
IUUC-Loc-051779	Lepisosteus oculatus	61.64	2.00e-161	561.00
IUUC-Lma-052969	Leptosphaeria maculans	24.16	6.00e-31	128.00
IUUC-Laf-053488	Loxodonta africana	88.60	0.00e+00	845.00
IUUC-Mcc-054701	Macaca mulatta	90.35	0.00e+00	833.00
IUUC-Meu-056577	Macropus eugenii	93.45	2.00e-149	522.00
IUUC-Mor-057157	Magnaporthe oryzae	23.06	2.00e-30	127.00
IUUC-Mpo-057518	Magnaporthe poae	21.64	2.00e-30	127.00
IUUC-Mtr-058125	Medicago truncatula	29.14	2.00e-53	203.00
IUUC-Mga-059906	Meleagris gallopavo	86.18	0.00e+00	795.00
IUUC-Mvi-060374	Microbotryum violaceum	31.86	5.00e-32	132.00
IUUC-Mmr-061786	Microcebus murinus	91.01	0.00e+00	836.00
IUUC-Mmu-063521	Mus musculus	86.14	0.00e+00	748.00
IUUC-Mac-065119	Musa acuminata	28.93	5.00e-44	172.00
IUUC-Mpu-066274	Mustela putorius furo	90.35	0.00e+00	832.00
IUUC-Mlu-067202	Myotis lucifugus	86.18	0.00e+00	785.00
IUUC-Nfi-068564	Neosartorya fischeri	24.62	8.00e-35	141.00
IUUC-Ncr-068823	Neurospora crassa	23.29	2.00e-33	137.00
IUUC-Nle-068987	Nomascus leucogenys	90.35	0.00e+00	834.00
IUUC-Opr-070453	Ochotona princeps	88.60	0.00e+00	810.00
IUUC-Ont-072611	Oreochromis niloticus	58.95	5.00e-165	573.00
IUUC-Oan-073738	Ornithorhynchus anatinus	87.94	0.00e+00	815.00
IUUC-Ocu-074396	Oryctolagus cuniculus	88.82	0.00e+00	818.00
IUUC-Oba-075472	Oryza barthii	30.27	1.00e-48	187.00
IUUC-Obr-076277	Oryza brachyantha	29.61	1.00e-50	194.00
IUUC-Ogl-077046	Oryza glaberrima	29.96	2.00e-47	183.00
IUUC-Ogu-078634	Oryza glumaepatula	30.27	5.00e-49	189.00
IUUC-Oin-080080	Oryza indica	28.67	2.00e-48	186.00
IUUC-Olo-080828	Oryza longistaminata	27.77	7.00e-47	182.00
IUUC-Ome-081387	Oryza meridionalis	28.03	1.00e-50	194.00
IUUC-Oni-082934	Oryza nivara	30.27	4.00e-49	189.00
IUUC-Opu-083719	Oryza punctata	29.16	2.00e-45	176.00
IUUC-Oru-084518	Oryza rufipogon	30.27	5.00e-49	189.00
IUUC-Ola-087312	Oryzias latipes	59.31	7.00e-164	570.00
IUUC-Olu-087661	Ostreococcus lucimarinus	29.27	1.00e-50	194.00
IUUC-Oga-089129	Otolemur garnettii	91.21	0.00e+00	834.00
IUUC-Oar-089839	Ovis aries	89.69	0.00e+00	828.00
IUUC-Ptr-091626	Pan troglodytes	90.35	0.00e+00	834.00
IUUC-Pan-092798	Papio anubis	90.35	0.00e+00	833.00
IUUC-Psi-093253	Pelodiscus sinensis	87.28	0.00e+00	825.00
IUUC-Pma-094512	Petromyzon marinus	55.84	1.00e-150	526.00
IUUC-Pno-094937	Phaeosphaeria nodorum	22.65	1.00e-30	127.00
IUUC-Ppa-095211	Physcomitrella patens	30.52	1.00e-59	224.00
IUUC-Pfo-097049	Poecilia formosa	54.26	1.00e-143	502.00
IUUC-Pab-097911	Pongo abelii	90.35	0.00e+00	835.00
IUUC-Pop-099841	Populus trichocarpa	29.98	1.00e-54	207.00
IUUC-Pca-100814	Procavia capensis	70.39	7.00e-174	603.00
IUUC-Ppe-101972	Prunus persica	29.98	8.00e-55	207.00
IUUC-Pva-103038	Pteropus vampyrus	89.25	0.00e+00	820.00
IUUC-Pgr-103277	Puccinia graminis	26.79	4.00e-39	155.00
IUUC-Ptt-103855	Puccinia triticina	26.28	3.00e-38	152.00
IUUC-Pte-104113	Pyrenophora teres	24.16	8.00e-29	121.00
IUUC-Pyt-104619	Pyrenophora triticirepentis	24.73	3.00e-29	123.00
IUUC-Rno-106003	Rattus norvegicus	85.81	0.00e+00	752.00
IUUC-Sce-106287	Saccharomyces cerevisiae	27.27	2.00e-21	97.10
IUUC-Sha-106652	Sarcophilus harrisii	99.56	0.00e+00	940.00
IUUC-Spo-108167	Schizosaccharomyces pombe	30.84	4.00e-55	208.00
IUUC-Smo-109393	Selaginella moellendorffii	30.52	5.00e-53	202.00
IUUC-Sit-110529	Setaria italica	32.44	2.00e-48	187.00
IUUC-Sly-111829	Solanum lycopersicum	30.60	1.00e-56	214.00
IUUC-Stu-112811	Solanum tuberosum	29.93	1.00e-55	211.00
IUUC-Sar-113259	Sorex araneus	86.33	4.00e-133	468.00
IUUC-Sbi-114591	Sorghum bicolor	29.94	6.00e-39	155.00
IUUC-Sre-115227	Sporisorium reilianum	25.52	1.00e-39	157.00
IUUC-Ssc-115293	Sus scrofa	88.82	0.00e+00	818.00
IUUC-Tgu-117335	Taeniopygia guttata	87.50	0.00e+00	827.00
IUUC-Tru-118458	Takifugu rubripes	58.46	5.00e-160	557.00
IUUC-Tsy-119475	Tarsius syrichta	90.78	0.00e+00	746.00
IUUC-Tni-119827	Tetraodon nigroviridis	58.37	1.00e-159	556.00
IUUC-Tca-121023	Theobroma cacao	31.36	8.00e-57	215.00
IUUC-Tre-121965	Trichoderma reesei	22.88	3.00e-33	136.00
IUUC-Tvi-122564	Trichoderma virens	21.36	2.00e-29	124.00
IUUC-Tae-124793	Triticum aestivum	31.43	2.00e-44	173.00
IUUC-Tur-126258	Triticum urartu	29.13	1.00e-44	174.00
IUUC-Tbe-127227	Tupaia belangeri	94.03	1.00e-71	263.00
IUUC-Ttr-128984	Tursiops truncatus	67.11	4.00e-167	580.00
IUUC-Uma-129565	Ustilago maydis	24.40	5.00e-35	142.00
IUUC-Vpa-130301	Vicugna pacos	91.01	0.00e+00	836.00
IUUC-Vvi-131244	Vitis vinifera	31.55	7.00e-58	218.00
IUUC-Xtr-132880	Xenopus tropicalis	63.26	1.00e-174	605.00
IUUC-Xma-134055	Xiphophorus maculatus	58.91	5.00e-162	564.00
IUUC-Yli-134342	Yarrowia lipolytica	29.19	7.00e-47	181.00
IUUC-Zma-135021	Zea mays	31.55	5.00e-41	162.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence