iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oar-090386

Ensembl Protein ID

ENSOARP00000005593.1

UniProt Accession

W5P590; W5P590_SHEEP

Genbank Protein ID

ENSOARP00000005593

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AMGL01024520

Gene Name

OPTN

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOARG00000005206.1	ENSOART00000005680.1	ENSOARP00000005593.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/Alpha-Helix/UBAN	2.40e-24	85.2	448	504

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/UBAN

   S: 1    keelletvevLkqQveiYkeDFqaERadRErlneekeeLqeqveklqkqvsklndsl 57
           +e++let+ vL++Q+e+Y++DF+aERa+RE+++eeke+L+ q+++l+k++++++d++
   Q: 448  QEKDLETMAVLRAQMEVYCSDFHAERAAREKIHEEKEQLALQLAVLLKENNAFEDGG 504
           6899**************************************************986 PP

Organism

Ovis aries

Protein Sequence
(Fasta)

MSHQPLSCLT EKGDSPSETT GNGPPNLAHP NLDTFTPHEL LQQMRELLIE NHQLKEAMKL 60
NNQAMKGRFE ELSAWTEKQK EERLYFETQS KEAKERLTAL SLENEKLKQE LGKLTGKTER 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGCCTGCCGG GGGGGCTGCC TGCCGAGGGG CGGGGCCCGG GGGGGGGGGG CNNNNNNNNN 60
NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN NNNNNNNNNN 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR032419--CC2-LZ_dom
IPR021063--NEMO_N
IPR032939--Optineurin
IPR034735--ZF_CCHC_NOA

PROSITE

PS51801--ZF_CCHC_NOA

Pfam

PF16516--CC2-LZ
PF11577--NEMO

Gene Ontology

GO:0031410--C:cytoplasmic vesicle
GO:0005829--C:cytosol
GO:0048471--C:perinuclear region of cytoplasm
GO:0005802--C:trans-Golgi network
GO:0050829--P:defense response to Gram-negative bacterium
GO:0090161--P:Golgi ribbon formation
GO:0043001--P:Golgi to plasma membrane protein transport
GO:0016236--P:macroautophagy
GO:0043124--P:negative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0001920--P:negative regulation of receptor recycling
GO:0061734--P:parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization
GO:1904417--P:positive regulation of xenophagy
GO:0000042--P:protein targeting to Golgi

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002037	Ailuropoda melanoleuca	81.08	0.00e+00	813.00
IUUC-Apl-003812	Anas platyrhynchos	56.03	6.00e-145	507.00
IUUC-Aca-004625	Anolis carolinensis	53.18	4.00e-142	498.00
IUUC-Bta-013240	Bos taurus	97.91	0.00e+00	1063.00
IUUC-Cja-019911	Callithrix jacchus	83.07	0.00e+00	838.00
IUUC-Cfa-020330	Canis familiaris	85.89	0.00e+00	865.00
IUUC-Cpo-021753	Cavia porcellus	80.03	0.00e+00	817.00
IUUC-Csa-023662	Chlorocebus sabaeus	83.59	0.00e+00	844.00
IUUC-Cho-024574	Choloepus hoffmanni	66.41	1.00e-123	436.00
IUUC-Cme-027299	Cyanidioschyzon merolae	36.99	1.70e-02	34.30
IUUC-Dre-027720	Danio rerio	41.25	2.00e-92	333.00
IUUC-Dno-029079	Dasypus novemcinctus	79.62	0.00e+00	769.00
IUUC-Dor-030890	Dipodomys ordii	80.14	0.00e+00	817.00
IUUC-Ete-032568	Echinops telfairi	77.90	0.00e+00	686.00
IUUC-Eca-033528	Equus caballus	85.81	0.00e+00	874.00
IUUC-Eeu-035219	Erinaceus europaeus	74.87	0.00e+00	796.00
IUUC-Fca-035852	Felis catus	83.62	0.00e+00	874.00
IUUC-Fal-036862	Ficedula albicollis	58.41	6.00e-141	494.00
IUUC-Gmo-038735	Gadus morhua	37.64	3.00e-71	262.00
IUUC-Gga-040939	Gallus gallus	55.77	5.00e-145	508.00
IUUC-Gac-041580	Gasterosteus aculeatus	43.42	3.00e-93	335.00
IUUC-Ggo-045034	Gorilla gorilla	75.04	0.00e+00	758.00
IUUC-Hsa-046624	Homo sapiens	82.90	0.00e+00	836.00
IUUC-Itr-048288	Ictidomys tridecemlineatus	75.43	0.00e+00	794.00
IUUC-Lch-049720	Latimeria chalumnae	50.00	2.00e-78	285.00
IUUC-Loc-052185	Lepisosteus oculatus	44.33	2.00e-100	359.00
IUUC-Laf-054079	Loxodonta africana	81.29	0.00e+00	819.00
IUUC-Mcc-055674	Macaca mulatta	84.47	0.00e+00	843.00
IUUC-Meu-056769	Macropus eugenii	79.29	2.00e-67	249.00
IUUC-Mga-060203	Meleagris gallopavo	57.12	3.00e-137	481.00
IUUC-Mmr-061492	Microcebus murinus	82.06	0.00e+00	815.00
IUUC-Mdo-063051	Monodelphis domestica	74.02	0.00e+00	775.00
IUUC-Mmu-063409	Mus musculus	77.44	0.00e+00	863.00
IUUC-Mpu-065907	Mustela putorius furo	78.40	0.00e+00	840.00
IUUC-Mlu-066957	Myotis lucifugus	82.06	0.00e+00	783.00
IUUC-Ncr-068766	Neurospora crassa	33.33	3.70e-02	33.10
IUUC-Nle-069973	Nomascus leucogenys	82.41	0.00e+00	827.00
IUUC-Opr-071049	Ochotona princeps	74.78	0.00e+00	709.00
IUUC-Ont-071915	Oreochromis niloticus	43.36	9.00e-89	320.00
IUUC-Oan-072965	Ornithorhynchus anatinus	71.58	0.00e+00	751.00
IUUC-Ocu-074029	Oryctolagus cuniculus	72.23	0.00e+00	634.00
IUUC-Ola-087019	Oryzias latipes	42.67	4.00e-86	312.00
IUUC-Oga-088613	Otolemur garnettii	82.44	0.00e+00	832.00
IUUC-Ptr-091619	Pan troglodytes	82.56	0.00e+00	831.00
IUUC-Pan-092178	Papio anubis	82.82	0.00e+00	827.00
IUUC-Psi-093214	Pelodiscus sinensis	60.76	3.00e-157	548.00
IUUC-Pfo-096901	Poecilia formosa	40.18	6.00e-82	298.00
IUUC-Pab-097560	Pongo abelii	75.47	0.00e+00	721.00
IUUC-Pca-100853	Procavia capensis	72.89	6.00e-121	427.00
IUUC-Pva-102255	Pteropus vampyrus	82.47	0.00e+00	776.00
IUUC-Rno-105812	Rattus norvegicus	78.33	0.00e+00	836.00
IUUC-Sha-107225	Sarcophilus harrisii	77.21	6.00e-151	526.00
IUUC-Sit-110549	Setaria italica	29.09	3.20e-01	29.30
IUUC-Sar-113736	Sorex araneus	70.15	2.00e-127	449.00
IUUC-Ssc-115422	Sus scrofa	91.81	0.00e+00	966.00
IUUC-Tgu-116924	Taeniopygia guttata	57.01	3.00e-142	498.00
IUUC-Tru-117695	Takifugu rubripes	39.05	1.00e-82	300.00
IUUC-Tsy-119090	Tarsius syrichta	79.55	1.00e-147	516.00
IUUC-Tni-120645	Tetraodon nigroviridis	41.03	8.00e-85	307.00
IUUC-Tbe-127970	Tupaia belangeri	70.38	4.00e-132	464.00
IUUC-Ttr-129244	Tursiops truncatus	90.62	0.00e+00	912.00
IUUC-Vpa-130313	Vicugna pacos	89.41	0.00e+00	863.00
IUUC-Xtr-132115	Xenopus tropicalis	43.67	1.00e-93	337.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence