iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSG00000106443.15	ENST00000521747.5	ENSP00000428601.1
ENSG00000106443.15	ENST00000403050.7	ENSP00000385795.3
ENSG00000106443.15	ENST00000634607.1	ENSP00000489535.1

Annotation

Cancer Mutation
TCGA	ICGC	COSMIC	CGAP
IntOGen
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress	TCGA	ICGC
COSMIC	THPA	HPM
DNA & RNA Element
UTRdb	AREsite	circBase	circRNADb
CircNet	miRTarBase	microRNA	TRANSFAC
RepTar	SomamiR	miRcode	RAID2
Protein-protein Interaction
HINT	InWeb_IM
Disease-associated Variation
ClinVar	GWASdb
Post-translational Modifications (PTMs)
PHOSIDA	BioGRID	mUbiSiDa
DNA Methylation
TCGA	ICGC
Protein Expression/Proteomics
THPA	HPM	GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	6.50e-17	63.1	870	920

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 3    vClvCgeggedekslveCekCrewfHpaClklsveeelpnsek..wiCpkCrs 53
            C+ C+ +g++e +lv+C++Cr ++H++Cl ++  ++ p+++   wiC++C+s
   Q: 870  ECATCKGTGDNE-NLVRCDECRLCYHFGCLDPP-LKKSPKQTGygWICQECDS 920
           6********977.7*******************.77777776679******86 PP

Organism

Homo sapiens

Protein Sequence
(Fasta)

MDRSSKRRQV KPLAASLLEA LDYDSSDDSD FKVGDASDSE GSGNGSEDAS KDSGEGSCSD 60
SEENILEEEL NEDIKVKEEQ LKNSAEEEVL SSEKQLIKME KKEEEENGER PRKKKEKEKE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACTTCCTTTT CAGAGCTGTA TCCGGGTCGC TGCTTTCCCT ATTGTCTGAG GCAGCCGCCC 60
TCGCGCTGTG CAATTTCTGG TCTTTCGTTG CTTCTGGTCC AGGCTAATAA AGTTTTTCTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR034732--EPHD
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51805--EPHD
PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF00628--PHD

SMART

SM00249--PHD

Gene Ontology

GO:0008270--F:zinc ion binding

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001978	Ailuropoda melanoleuca	97.37	0.00e+00	1494.00
IUUC-Apl-003491	Anas platyrhynchos	94.40	0.00e+00	1329.00
IUUC-Aca-004470	Anolis carolinensis	90.86	0.00e+00	1301.00
IUUC-Ame-011188	Astyanax mexicanus	82.18	0.00e+00	1053.00
IUUC-Bta-012312	Bos taurus	95.59	0.00e+00	1389.00
IUUC-Cel-018258	Caenorhabditis elegans	28.32	1.00e-47	184.00
IUUC-Cja-019931	Callithrix jacchus	99.05	0.00e+00	1527.00
IUUC-Cfa-021102	Canis familiaris	98.77	0.00e+00	1467.00
IUUC-Csa-023396	Chlorocebus sabaeus	98.85	0.00e+00	1469.00
IUUC-Cin-025300	Ciona intestinalis	34.85	5.00e-75	275.00
IUUC-Csv-026365	Ciona savignyi	59.65	4.00e-16	75.90
IUUC-Dre-028450	Danio rerio	82.17	0.00e+00	1044.00
IUUC-Dno-029245	Dasypus novemcinctus	96.60	0.00e+00	1387.00
IUUC-Dme-031650	Drosophila melanogaster	38.88	2.00e-118	420.00
IUUC-Ete-032829	Echinops telfairi	84.04	0.00e+00	1197.00
IUUC-Eca-033527	Equus caballus	98.97	0.00e+00	1470.00
IUUC-Eeu-035092	Erinaceus europaeus	85.14	0.00e+00	1047.00
IUUC-Fal-037349	Ficedula albicollis	93.53	0.00e+00	1330.00
IUUC-Gmo-038924	Gadus morhua	80.95	0.00e+00	1027.00
IUUC-Gga-040604	Gallus gallus	93.41	0.00e+00	1360.00
IUUC-Gac-041895	Gasterosteus aculeatus	79.72	0.00e+00	1021.00
IUUC-Ggo-044724	Gorilla gorilla	93.41	0.00e+00	1339.00
IUUC-Lch-050481	Latimeria chalumnae	92.26	0.00e+00	1245.00
IUUC-Loc-052530	Lepisosteus oculatus	84.72	0.00e+00	1258.00
IUUC-Laf-053683	Loxodonta africana	97.31	0.00e+00	1436.00
IUUC-Mcc-055254	Macaca mulatta	98.60	0.00e+00	1467.00
IUUC-Meu-056124	Macropus eugenii	72.46	0.00e+00	948.00
IUUC-Mmr-061716	Microcebus murinus	99.61	0.00e+00	1479.00
IUUC-Mmu-064063	Mus musculus	98.06	0.00e+00	1419.00
IUUC-Mpu-065850	Mustela putorius furo	96.49	0.00e+00	1404.00
IUUC-Mlu-067977	Myotis lucifugus	98.16	0.00e+00	1336.00
IUUC-Nle-070024	Nomascus leucogenys	99.13	0.00e+00	1480.00
IUUC-Opr-070669	Ochotona princeps	83.80	0.00e+00	1111.00
IUUC-Ont-072407	Oreochromis niloticus	73.42	0.00e+00	1148.00
IUUC-Oga-088503	Otolemur garnettii	99.58	0.00e+00	1342.00
IUUC-Oar-090254	Ovis aries	97.26	0.00e+00	1515.00
IUUC-Ptr-090811	Pan troglodytes	100.00	0.00e+00	1342.00
IUUC-Psi-093869	Pelodiscus sinensis	94.41	0.00e+00	1370.00
IUUC-Pma-094703	Petromyzon marinus	61.40	0.00e+00	759.00
IUUC-Pfo-097375	Poecilia formosa	83.80	0.00e+00	1021.00
IUUC-Pab-098645	Pongo abelii	100.00	0.00e+00	1475.00
IUUC-Pca-100931	Procavia capensis	88.28	0.00e+00	950.00
IUUC-Pva-102902	Pteropus vampyrus	94.19	0.00e+00	1432.00
IUUC-Rno-105725	Rattus norvegicus	97.49	0.00e+00	1371.00
IUUC-Sha-107008	Sarcophilus harrisii	92.45	0.00e+00	1365.00
IUUC-Sar-113710	Sorex araneus	89.63	0.00e+00	1031.00
IUUC-Ssc-116271	Sus scrofa	97.54	0.00e+00	1399.00
IUUC-Tru-117706	Takifugu rubripes	82.15	0.00e+00	1085.00
IUUC-Tsy-118886	Tarsius syrichta	99.23	0.00e+00	1460.00
IUUC-Tni-120623	Tetraodon nigroviridis	81.05	0.00e+00	999.00
IUUC-Tbe-127618	Tupaia belangeri	86.46	3.00e-135	476.00
IUUC-Ttr-129058	Tursiops truncatus	94.45	0.00e+00	1372.00
IUUC-Vpa-130327	Vicugna pacos	96.90	0.00e+00	1465.00
IUUC-Xtr-132030	Xenopus tropicalis	78.11	0.00e+00	1240.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence