iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSSCG00000012273.3	ENSSSCT00000013421.3	ENSSSCP00000013061.3
ENSSSCG00000012273.3	ENSSSCT00000034750.1	ENSSSCP00000028691.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	8.00e-112	374.0	262	888

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgye 88
           +Gl+NlgNtC+mNS+LQcLsn+p+l+e++l+ ++ e+ln  np ++kge+++++++l+++ w+++++++ p+ ++++++++a++f gy+
   Q: 262  CGLTNLGNTCFMNSALQCLSNVPQLTEYFLKnRYLEELNFCNPLGMKGEIAEAYADLVKQAWSGHHRSIVPHVFKTKVGHFASQFLGYQ 350
           7*****************************999******************************************************** PP
   S: 89   qqDaqEflaflldqleeelkkeknkpkeeeeeedkselsde...aeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlsl 174
           q+D+qE+l+flld+l+e+l++ k+k++ e+++++ +  ++    a++++k++n+s+i+d+F+g +ks+++c++c+nvs++++pf++ls+
   Q: 351  QHDSQELLSFLLDGLHEDLNRVKKKEYVELCDAAGRPDQEVaqeAWQNHKRRNDSVIVDTFHGLFKSTLVCPDCGNVSVTFDPFCYLSV 439
           *****************************998874333322555********************************************* PP
   S: 175  pvpgkeetkke.............................................................................. 185
           p+p ++++ +e                                                                              
   Q: 440  PLPVSHKRVMEvffvsmdprrkpeqhrlvvpkkgkisdlcvalakhtgvspermmvadvfshrfykiyqleeslssildrddifiyevs 528
           ******99988****************************************************************************** PP
   S: 186  ......................................................................................... 185
                                                                                                    
   Q: 529  graaigensredvvlpiylrertpardynnsyyglmlfghpllvsvprdrlswdalyhillyrlsryvtrpssddeddgdekdledkdt 617
           ***************************************************************************************** PP
   S: 186  ......................................................................................... 185
                                                                                                    
   Q: 618  lpkpghvagsssqdpgleqagpssgvaggsrapvdnspgpshwpqrarrkhlftlqtvnsngtsdrstfnedthgvsfssqpyiaidwe 706
           ***************************************************************************************** PP
   S: 186  ...............................slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeq 243
                                           lq+c+e ft+ e+le+en +yc++ck++q a+kkl+l+ lPe+Li+hLkRfs+++  
   Q: 707  pemkkryydeveaegyvkhdcvgyvlkkapvRLQECIELFTTVETLEKENPWYCPTCKQHQLATKKLDLWMLPETLIIHLKRFSYTK-- 793
           ***********************************************************************************8866.. PP
   S: 244  ksrekinkkvefple.Ldlspfctspeekqke.kkkYeLiavvvHsGslssGHYvayvkn.ekgkWllfdDskVtevkeeevleetgst 329
            srek+++ vefp++ Ld s+f+++p+++++   +kY+Liav +H+G+l+ GHY++++ n ++g+W +fdD++V++v+e+++++   + 
   Q: 794  FSREKLDTLVEFPIRdLDFSEFVIKPQNESAPeLYKYDLIAVSNHYGGLRDGHYTTFACNkDSGQWHYFDDNSVSPVTENQIES---KA 879
           89*********************999887754489*********************988834566*******************...** PP
   S: 330  aYvlfYkrr 338
           aYvlfY+r+
   Q: 880  AYVLFYQRQ 888
           *******96 PP

Organism

Sus scrofa

Protein Sequence
(Fasta)

XSGGRTAMAA VAASPAAAAE DQELQREAVP GLESQRRQIE NGENGRGRPL QAGESWFLVE 60
QHWYQKWEEY VQGGDQDSST SPGCINNAGL FEDQVNWRLK KGLVEGEDYV LLPAAAWHYL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAGTGGAGGG CGAACGGCTA TGGCGGCGGT CGCAGCGAGT CCAGCGGCTG CGGCCGAGGA 60
CCAAGAGCTA CAGCGCGAAG CGGTGCCGGG CCTCGAGAGC CAGCGGCGCC AGATCGAAAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome

Interpro

IPR006615--Pept_C19_DUSP
IPR001394--Peptidase_C19_UCH
IPR028135--Ub_USP-typ
IPR029346--USP_C
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS51283--DUSP
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF06337--DUSP
PF14836--Ubiquitin_3
PF00443--UCH
PF14533--USP7_C2

SMART

SM00695--DUSP

Gene Ontology

GO:0005829--C:cytosol
GO:0005654--C:nucleoplasm
GO:0005634--C:nucleus
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001760	Ailuropoda melanoleuca	92.30	0.00e+00	1692.00
IUUC-Aca-004532	Anolis carolinensis	64.59	0.00e+00	1159.00
IUUC-Afu-008878	Aspergillus fumigatus	38.73	6.00e-56	213.00
IUUC-Ate-010323	Aspergillus terreus	36.87	4.00e-57	217.00
IUUC-Bta-013284	Bos taurus	92.42	0.00e+00	1632.00
IUUC-Cel-018257	Caenorhabditis elegans	32.14	4.00e-95	343.00
IUUC-Cja-019746	Callithrix jacchus	82.83	0.00e+00	1496.00
IUUC-Cfa-020134	Canis familiaris	93.38	0.00e+00	1700.00
IUUC-Cpo-022535	Cavia porcellus	76.56	0.00e+00	1449.00
IUUC-Csa-023828	Chlorocebus sabaeus	83.94	0.00e+00	1532.00
IUUC-Dno-028853	Dasypus novemcinctus	89.90	0.00e+00	1425.00
IUUC-Dor-030384	Dipodomys ordii	80.16	0.00e+00	1447.00
IUUC-Eca-033271	Equus caballus	93.57	0.00e+00	1667.00
IUUC-Fca-036012	Felis catus	92.79	0.00e+00	1711.00
IUUC-Fso-038291	Fusarium solani	44.49	3.00e-64	241.00
IUUC-Gac-042574	Gasterosteus aculeatus	55.98	0.00e+00	915.00
IUUC-Hsa-046551	Homo sapiens	83.94	0.00e+00	1532.00
IUUC-Itr-048915	Ictidomys tridecemlineatus	80.71	0.00e+00	1454.00
IUUC-Kpa-049332	Komagataella pastoris	33.04	2.00e-70	261.00
IUUC-Laf-054561	Loxodonta africana	85.71	0.00e+00	1596.00
IUUC-Mcc-054881	Macaca mulatta	83.72	0.00e+00	1531.00
IUUC-Meu-056749	Macropus eugenii	83.96	0.00e+00	942.00
IUUC-Mla-058848	Melampsora laricipopulina	41.71	2.00e-72	267.00
IUUC-Mvi-060324	Microbotryum violaceum	31.77	7.00e-81	295.00
IUUC-Mmr-061400	Microcebus murinus	85.67	0.00e+00	1560.00
IUUC-Mdo-062470	Monodelphis domestica	82.66	0.00e+00	810.00
IUUC-Mmu-063241	Mus musculus	76.84	0.00e+00	1421.00
IUUC-Mpu-066507	Mustela putorius furo	93.59	0.00e+00	1740.00
IUUC-Mlu-066961	Myotis lucifugus	82.87	0.00e+00	1505.00
IUUC-Nle-069284	Nomascus leucogenys	83.83	0.00e+00	1534.00
IUUC-Ont-071847	Oreochromis niloticus	59.36	0.00e+00	1005.00
IUUC-Oan-073387	Ornithorhynchus anatinus	72.72	0.00e+00	1266.00
IUUC-Ocu-074066	Oryctolagus cuniculus	83.06	0.00e+00	1496.00
IUUC-Ola-086500	Oryzias latipes	55.12	0.00e+00	940.00
IUUC-Oga-088424	Otolemur garnettii	84.94	0.00e+00	1544.00
IUUC-Oar-089732	Ovis aries	89.31	0.00e+00	1618.00
IUUC-Pan-092292	Papio anubis	84.36	0.00e+00	1528.00
IUUC-Pab-098779	Pongo abelii	76.07	0.00e+00	1311.00
IUUC-Pca-100851	Procavia capensis	86.51	0.00e+00	922.00
IUUC-Pva-103244	Pteropus vampyrus	90.00	0.00e+00	1629.00
IUUC-Ptt-103847	Puccinia triticina	36.29	2.00e-64	241.00
IUUC-Rno-105100	Rattus norvegicus	77.63	0.00e+00	1429.00
IUUC-Sha-107502	Sarcophilus harrisii	82.23	0.00e+00	932.00
IUUC-Sja-107752	Schizosaccharomyces japonicus	35.80	3.00e-81	296.00
IUUC-Spo-108291	Schizosaccharomyces pombe	32.11	2.00e-74	273.00
IUUC-Smo-108686	Selaginella moellendorffii	38.57	4.00e-113	401.00
IUUC-Sar-113704	Sorex araneus	75.47	0.00e+00	798.00
IUUC-Tru-117788	Takifugu rubripes	58.90	0.00e+00	961.00
IUUC-Tsy-119414	Tarsius syrichta	76.38	0.00e+00	1073.00
IUUC-Tni-120107	Tetraodon nigroviridis	50.86	3.00e-161	561.00
IUUC-Tvi-122422	Trichoderma virens	41.91	6.00e-58	219.00
IUUC-Tbe-128081	Tupaia belangeri	86.96	0.00e+00	984.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence