iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oga-088774

Ensembl Protein ID

ENSOGAP00000020816.1

UniProt Accession

H0XXH3; H0XXH3_OTOGA

Genbank Protein ID

ENSOGAP00000020816

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAQR03150388

Gene Name

HIC1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOGAG00000034845.1	ENSOGAT00000030320.1	ENSOGAP00000020816.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_Other: BTB	1.10e-12	48.1	47	106

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_Other: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveik.d.vqpevfrallkFlYtgkl 65
           +Dvi+vv++  f+ahk vLaasS ++++l  +        +  +++ d v+p vfr +l+F+Ytg+l
   Q: 47   CDVIIVVQNALFRAHKNVLAASSAYLKSLVVH-------DNLLNLDhDmVSPAVFRLVLDFIYTGRL 106
           9*****************************77.......4566677678****************98 PP

Organism

Otolemur garnettii

Protein Sequence
(Fasta)

MTFPEADILL KSGECAGQTM LDTMEAPGHS RQLLLQLNNQ RTKGFLCDVI IVVQNALFRA 60
HKNVLAASSA YLKSLVVHDN LLNLDHDMVS PAVFRLVLDF IYTGRLADGA EAAAAASVAP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGACTTTTC CTGAAGCGGA CATTTTACTT AAATCGGGTA ACTGTCTCCG AAAGGGTCAC 60
TTCGTCAGAA CAGTGTTCTC CTCGGAAGCC CCCAGCACCC AGCCCGTGTG CCCAGTGGGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000210--BTB/POZ_dom
IPR023413--GFP-like
IPR028424--HIC1
IPR004039--Rubredoxin-type_fold
IPR011333--SKP1/BTB/POZ
IPR013087--Znf_C2H2_type
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50097--BTB
PS00028--ZINC_FINGER_C2H2_1
PS50157--ZINC_FINGER_C2H2_2

Pfam

PF00651--BTB

SMART

SM00225--BTB
SM00355--ZnF_C2H2

Gene Ontology

GO:0005829--C:cytosol
GO:0005654--C:nucleoplasm
GO:0046872--F:metal ion binding
GO:0043565--F:sequence-specific DNA binding
GO:0003700--F:transcription factor activity, sequence-specific DNA binding
GO:0008630--P:intrinsic apoptotic signaling pathway in response to DNA damage
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0030178--P:negative regulation of Wnt signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001347	Ailuropoda melanoleuca	90.66	7.00e-153	533.00
IUUC-Aca-004680	Anolis carolinensis	76.04	1.00e-68	254.00
IUUC-Ame-010967	Astyanax mexicanus	60.24	7.00e-94	338.00
IUUC-Bta-013567	Bos taurus	96.57	2.00e-162	566.00
IUUC-Cja-019621	Callithrix jacchus	98.94	8.00e-47	178.00
IUUC-Cfa-020731	Canis familiaris	95.09	0.00e+00	923.00
IUUC-Cpo-021326	Cavia porcellus	91.82	0.00e+00	882.00
IUUC-Csa-023645	Chlorocebus sabaeus	96.04	0.00e+00	892.00
IUUC-Dno-028900	Dasypus novemcinctus	94.59	0.00e+00	870.00
IUUC-Fal-036980	Ficedula albicollis	62.90	6.00e-112	397.00
IUUC-Gga-040708	Gallus gallus	59.62	0.00e+00	628.00
IUUC-Ggo-044591	Gorilla gorilla	99.70	7.00e-140	490.00
IUUC-Hsa-046769	Homo sapiens	96.32	0.00e+00	877.00
IUUC-Itr-048627	Ictidomys tridecemlineatus	93.78	0.00e+00	880.00
IUUC-Lch-049412	Latimeria chalumnae	53.72	0.00e+00	633.00
IUUC-Loc-051883	Lepisosteus oculatus	63.47	2.00e-93	336.00
IUUC-Laf-053358	Loxodonta africana	92.60	7.00e-168	583.00
IUUC-Mcc-054981	Macaca mulatta	95.94	0.00e+00	853.00
IUUC-Meu-056181	Macropus eugenii	70.83	1.00e-115	409.00
IUUC-Mga-059592	Meleagris gallopavo	73.54	2.00e-102	366.00
IUUC-Mmr-061560	Microcebus murinus	94.26	0.00e+00	843.00
IUUC-Mdo-062511	Monodelphis domestica	66.76	4.00e-172	597.00
IUUC-Mmu-064258	Mus musculus	93.76	0.00e+00	884.00
IUUC-Mpu-065911	Mustela putorius furo	94.68	0.00e+00	888.00
IUUC-Mlu-067575	Myotis lucifugus	78.76	2.00e-122	432.00
IUUC-Ont-072493	Oreochromis niloticus	65.55	5.00e-80	292.00
IUUC-Ola-086584	Oryzias latipes	61.34	3.00e-89	322.00
IUUC-Ptr-090491	Pan troglodytes	99.59	1.00e-121	429.00
IUUC-Pma-094179	Petromyzon marinus	70.51	4.00e-31	125.00
IUUC-Pfo-096282	Poecilia formosa	58.86	5.00e-87	315.00
IUUC-Pab-098488	Pongo abelii	96.27	9.00e-174	603.00
IUUC-Pca-100667	Procavia capensis	95.76	3.00e-148	518.00
IUUC-Pva-102421	Pteropus vampyrus	93.86	0.00e+00	879.00
IUUC-Rno-105528	Rattus norvegicus	92.03	0.00e+00	874.00
IUUC-Sar-113478	Sorex araneus	98.76	2.00e-119	423.00
IUUC-Ssc-115420	Sus scrofa	92.59	0.00e+00	857.00
IUUC-Tgu-116642	Taeniopygia guttata	59.84	0.00e+00	629.00
IUUC-Tru-118583	Takifugu rubripes	60.44	3.00e-85	309.00
IUUC-Xtr-132210	Xenopus tropicalis	59.17	0.00e+00	665.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence