iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mdo-062720

UUCD1 version

UUC-MoD-00595

Ensembl Protein ID

ENSMODP00000015001.2

UniProt Accession

F7BA11; F7BA11_MONDO

Protein Name

Uncharacterized protein

Gene Name

CISH

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000011974.2	ENSMODT00000015276.2	ENSMODP00000015001.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box	4.20e-14	52.3	205	250

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box

   S: 3    klwllrseprSLqhLCRlaIrrclgsqrlkaidkLPLPksLkdYLlyedyq 53
           +++++ ++ +SLqhLCRl+I++++       +d+LPLPk++ dYL+++++q
   Q: 205  QPFVRKNSAPSLQHLCRLTINKLTAE-----VDQLPLPKRIGDYLRQYPFQ 250
           678999******************99.....8****************986 PP

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

MIFCIQGPHP LLEEERIGRL TLAGLTVGLP EPVMQPLSVT PFQEEEEAPP LTENELPQVR 60
DPEEDLLCIA KTFTYLRESG WYWGSLTAFE AKQHLQKMPE GTFLVRDSTH PSYLFTLSVK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTCATTTCAA CGAGCTGCAG CCACAGGATA GGTCTTGTCT CCTGGGCTCC GGAATCCTCT 60
TGCTCATTTG ATCCTGGACC GGCTGCCAAG CTGGTGGTGC TGAACCTCTG GCCTGGCCTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR028425--CIS
IPR000980--SH2
IPR001496--SOCS_box

PROSITE

PS50001--SH2
PS50225--SOCS

Pfam

PF00017--SH2
PF07525--SOCS_box

PRINTS

PR00401--SH2DOMAIN

SMART

SM00252--SH2
SM00253--SOCS
SM00969--SOCS_box

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005886--C:plasma membrane
GO:0004860--F:protein kinase inhibitor activity
GO:0019221--P:cytokine-mediated signaling pathway
GO:0035556--P:intracellular signal transduction
GO:0046627--P:negative regulation of insulin receptor signaling pathway
GO:0046426--P:negative regulation of JAK-STAT cascade
GO:0006469--P:negative regulation of protein kinase activity
GO:0007205--P:protein kinase C-activating G-protein coupled receptor signaling pathway
GO:0016567--P:protein ubiquitination

KEGG

mdo:100028873

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001189	Ailuropoda melanoleuca	70.75	6.00e-91	327.00
IUUC-Aca-004372	Anolis carolinensis	71.37	2.00e-101	361.00
IUUC-Ame-010787	Astyanax mexicanus	45.63	2.00e-51	195.00
IUUC-Bta-012826	Bos taurus	68.63	2.00e-96	345.00
IUUC-Cja-020004	Callithrix jacchus	69.44	6.00e-89	320.00
IUUC-Cfa-020150	Canis familiaris	69.20	4.00e-89	320.00
IUUC-Csa-023173	Chlorocebus sabaeus	66.67	4.00e-87	314.00
IUUC-Dno-028956	Dasypus novemcinctus	68.36	7.00e-93	333.00
IUUC-Dor-030148	Dipodomys ordii	60.00	2.00e-80	291.00
IUUC-Ete-032313	Echinops telfairi	67.97	4.00e-86	310.00
IUUC-Eca-033422	Equus caballus	69.38	6.00e-97	346.00
IUUC-Eeu-034806	Erinaceus europaeus	68.13	4.00e-85	307.00
IUUC-Fca-036374	Felis catus	69.77	3.00e-96	344.00
IUUC-Fal-036801	Ficedula albicollis	71.65	2.00e-98	351.00
IUUC-Gmo-038483	Gadus morhua	42.05	5.00e-36	144.00
IUUC-Gga-040891	Gallus gallus	72.44	5.00e-95	340.00
IUUC-Ggo-045511	Gorilla gorilla	69.84	3.00e-88	318.00
IUUC-Hsa-046678	Homo sapiens	69.11	7.00e-93	333.00
IUUC-Itr-048397	Ictidomys tridecemlineatus	68.99	7.00e-97	346.00
IUUC-Lch-050555	Latimeria chalumnae	58.04	2.00e-73	268.00
IUUC-Laf-054141	Loxodonta africana	68.60	6.00e-98	350.00
IUUC-Mcc-055401	Macaca mulatta	67.06	7.00e-87	313.00
IUUC-Meu-056592	Macropus eugenii	91.46	1.00e-117	415.00
IUUC-Mga-059515	Meleagris gallopavo	72.47	8.00e-91	326.00
IUUC-Mmr-060848	Microcebus murinus	70.12	1.00e-91	329.00
IUUC-Mmu-063348	Mus musculus	68.60	6.00e-100	356.00
IUUC-Mpu-065834	Mustela putorius furo	69.77	2.00e-92	331.00
IUUC-Mlu-067687	Myotis lucifugus	67.97	7.00e-86	309.00
IUUC-Nle-069277	Nomascus leucogenys	69.11	1.00e-93	335.00
IUUC-Ont-071890	Oreochromis niloticus	45.41	8.00e-37	146.00
IUUC-Oan-073672	Ornithorhynchus anatinus	77.56	1.00e-105	375.00
IUUC-Ocu-073875	Oryctolagus cuniculus	67.73	6.00e-89	320.00
IUUC-Ola-087140	Oryzias latipes	47.97	2.00e-27	114.00
IUUC-Oga-087943	Otolemur garnettii	68.22	4.00e-93	333.00
IUUC-Oar-090194	Ovis aries	69.20	7.00e-93	333.00
IUUC-Ptr-090934	Pan troglodytes	69.44	2.00e-88	318.00
IUUC-Pan-092121	Papio anubis	67.57	4.00e-91	327.00
IUUC-Psi-093733	Pelodiscus sinensis	74.09	3.00e-102	364.00
IUUC-Pfo-096313	Poecilia formosa	49.23	1.00e-44	172.00
IUUC-Pab-098439	Pongo abelii	69.50	3.00e-93	334.00
IUUC-Pca-101010	Procavia capensis	68.99	3.00e-97	347.00
IUUC-Pva-103112	Pteropus vampyrus	67.05	8.00e-94	336.00
IUUC-Rno-105917	Rattus norvegicus	68.60	5.00e-91	327.00
IUUC-Sha-106954	Sarcophilus harrisii	90.55	9.00e-126	442.00
IUUC-Sar-113001	Sorex araneus	69.32	4.00e-89	320.00
IUUC-Ssc-115922	Sus scrofa	70.21	4.00e-50	189.00
IUUC-Tgu-117338	Taeniopygia guttata	73.68	5.00e-96	343.00
IUUC-Tru-118511	Takifugu rubripes	43.18	8.00e-32	129.00
IUUC-Tsy-119434	Tarsius syrichta	69.32	2.00e-90	325.00
IUUC-Ttr-128340	Tursiops truncatus	57.09	9.00e-64	236.00
IUUC-Vpa-130443	Vicugna pacos	69.41	2.00e-100	357.00
IUUC-Xtr-131784	Xenopus tropicalis	56.23	1.00e-73	269.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence